A Study to Compare and Correlate the Status of Maturation in Growing Individuals Using Chronological Age Dental Maturation and Cervical Vertebrae Maturation

Objective: The relationship between dental and skeletal development levels was determined in individuals with cleft lip and palate and a control group comprising individuals without cleft lip and palate. Design: Retrospective, cross-sectional study. Setting: A university clinic specializing in orthodontic and pedodontic care. Patients: A total of 198 patients with cleft lip and palate (99 females, 11.66 ± 2.36 years; 99 males, 12.44 ± 2.33 years) and 198 patients without cleft lip and palate (99 females, 11.88 ± 2.26 years; 99 males, 12.99 ± 2.25 years). Interventions: None. Main Outcome Measures: The Demirjian method and cervical vertebra maturation method were used to evaluate panoramic and lateral cephalometric radiographs, respectively. The Fishman maturation predictors were determined from hand-wrist radiographs. Results: Statistically significant correlations were found between the chronological age and the dental age in both the groups ( P < .05). Significant correlations between skeletal maturation indicators and dental maturation indicators were observed in both groups and sexes ( P < .05), with a stronger correlation among teeth with incomplete dental maturation. Dental age was found to be significantly lower (female, P = .001; male, P = .001) in individuals with cleft lip and palate (female, 11.71 ± 2.58 years; male, 12.51 ± 2.62 years) compared to those in the control group (female, 12.95 ± 2.47 years; male, 13.64 ± 2.37 years). Conclusions: A high correlation between the results of the evaluated radiographic methods and chronological age supports their use for accurate age estimation in the patients with cleft lip and palate.

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Chronological Age in Different Bone Development Stages: A Retrospective Comparative Study

Children ◽

10.3390/children8020142 ◽

2021 ◽

Vol 8 (2) ◽

pp. 142

Author(s):

Abel Emanuel Moca ◽

Luminița Ligia Vaida ◽

Rahela Tabita Moca ◽

Anamaria Violeta Țuțuianu ◽

Călin Florin Bochiș ◽

...

Keyword(s):

Retrospective Study ◽

Comparative Study ◽

Bone Development ◽

Skeletal Maturity ◽

Cervical Vertebrae ◽

Chronological Age ◽

Exclusion Criteria ◽

Development Stages ◽

Retrospective Comparative Study ◽

Cervical Vertebral Maturation

The assessment of an individual’s development by investigating the skeletal maturity is of much use in various medical fields. Skeletal maturity can be estimated by evaluating the morphology of the cervical vertebrae. The aim of this study was to conduct comparisons of the chronological age in different bone development stages. The retrospective study was conducted based on lateral cephalometric radiographs belonging to patients with ages between 6 and 15.9 years, from Romania. For the assessment of skeletal maturity, the Cervical Vertebral Maturation (CVM) method was used. In total, 356 radiographs were selected, but after applying the exclusion criteria, 252 radiographs remained in the study (178 girls and 74 boys). Different mean chronological age values were obtained for the general sample, as well as for the two genders. The chronological age started to be significantly different at the CS4 stage. Patients with CS4, CS5, and CS6 stages had a significantly higher chronological age compared to patients with CS1, CS2, and CS3 stages. It was noted that patients with CS1 and CS2 stages were more frequently boys, while patients with the CS5 stage were more frequently girls.

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Development and validation of a formula for objective assessment of cervical vertebral bone age

Progress in Orthodontics ◽

10.1186/s40510-020-00338-0 ◽

2020 ◽

Vol 21 (1) ◽

Author(s):

Raghavan Chandrasekar ◽

Shyamala Chandrasekhar ◽

K. K. Shantha Sundari ◽

Poornima Ravi

Keyword(s):

Cervical Vertebrae ◽

Objective Assessment ◽

Bone Age ◽

Chronological Age ◽

Strong Positive Correlation ◽

Vertebral Bone ◽

Indian Patients ◽

South Indian ◽

Lateral Cephalograms ◽

Significant Difference

Abstract Background and aim Determination of skeletal maturity and bone age from cervical vertebrae has been well documented. Most methods described use subjective evaluation of morphological characteristics of cervical vertebrae and may be prone to variability and error. A few objective methods have also been developed, specific for certain populations and genders. The aim of this study was to establish and validate an objective method to determine cervical vertebral bone age from lateral cephalometric radiographs, for Asian South Indian patients of both genders. Methods Ninety boys and 90 girls between 9 and 15 years of age were recruited, and their lateral cephalograms were taken. Using measurements made from the third and fourth cervical vertebrae, a formula to determine cervical vertebral bone age was derived using stepwise regression analysis. To validate the formula, a separate sample of 30 boys and 30 girls was chosen, and hand-wrist radiographs and lateral cephalograms were obtained. Cervical vertebral bone age (CVBA) was determined by applying the formula derived. Bone age was also calculated using the Tanner-Whitehouse 3 method. The bone ages determined by both methods were compared to each other and chronological age, using one-way ANOVA, Tukey’s post hoc analysis, and Pearson’s correlation coefficient. Results The formulae derived in the current study to determine CVBA differed for both genders. No statistically significant difference was found between CVBA, bone age derived by the Tanner-Whitehouse 3 method, and chronological age for both boys (p value = 0.425) and girls (p value = 0.995). A moderate to strong positive correlation was found between CVBA, bone age, and chronological age. Conclusion The formulae derived in this study were validated and are reliable for objectively determining cervical vertebral bone age and skeletal maturation from lateral cephalograms for Asian South Indian patients of both genders.

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The role of cervical vertebrae maturation in defining the chronological age of Down syndrome children

Dental Journal (Majalah Kedokteran Gigi) ◽

10.20473/j.djmkg.v50.i4.p220-225 ◽

2017 ◽

Vol 50 (4) ◽

pp. 220

Author(s):

Aggiani Dewi Rahmawati ◽

Iwan Ahmad ◽

Arlette Suzy Setyawan

Keyword(s):

Down Syndrome ◽

Normal Development ◽

Cervical Vertebrae ◽

T Test ◽

Skeletal Age ◽

Physiological Age ◽

Chronological Age ◽

Control Group ◽

Dental Age ◽

Children With Down Syndrome

Background: The difficulty of determining chronological age is increased in individuals with conditions that may affect normal development. Some systemic conditions in children, for example Down syndrome, may cause abnormal physiological maturation. Skeletal and dental age are considered the most apt physiological age indicators in determining chronological age. Purpose: This study aimed to compare and analyze the relationship between two developmental parameters (dental history and skeletal age) as indicators of the chronological age of children with Down syndrome. Methods: The study design was cross-sectional with a paired t-test to analyze the differences in chronological and dental age of the samples. The radiograph selection was based on purposive sampling. The study material consisted of 30 panoramic radiographs and lateral cephalometrics of 6-14 years old children with Down syndrome and those experiencing normal development (control group) divided into two groups of 15 subjects who attended the Pediatric Dentistry Polyclinic, RSGM, Universitas Padjadjaran. Statistical analysis employed a t-test to determine the difference between chronological and dental age, while a Spearman rank correlation was used to evaluate the correlation between dental and skeletal age. Results: The results showed there to be no statistical difference between chronological and dental age, where p > 0.05, but a significant relationship between dental and skeletal age in children diagnosed with Down syndrome, where p = 0.05. Conclusion: It is concluded that dental age identified by means of the Nolla method is closer to chronological age than skeletal age using the cervical vertebrae maturation method.

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Correlation between Cervical Vertebrae Maturation and Chronological Age: A Radiographic Study

World Journal of Dentistry ◽

10.5005/jp-journals-10015-1470 ◽

2017 ◽

Vol 8 (5) ◽

pp. 382-385

Author(s):

Santhakumar Madhu

Keyword(s):

Cervical Vertebrae ◽

Chronological Age ◽

Radiographic Study

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Dental age assessment on panoramic radiographs: Comparison between two generations of young Finnish subjects

Journal of International Medical Research ◽

10.1177/0300060518801437 ◽

2018 ◽

Vol 47 (1) ◽

pp. 311-324 ◽

Cited By ~ 1

Author(s):

Flavia A. Birchler ◽

Stavros Kiliaridis ◽

Christophe Combescure ◽

Johanna Julku ◽

Pertti M. Pirttiniemi ◽

...

Keyword(s):

Meta Analysis ◽

Chronological Age ◽

Dental Development ◽

Healthy Children ◽

Dental Age ◽

Age Assessment ◽

Dental Maturation ◽

Panoramic Radiographs ◽

Two Generations ◽

Maxilla And Mandible

Objective To analyse the accuracy of a meta-analysis-based dental age assessment (DAA) method in Finnish paediatric patients and to compare the dental development between two generations of Finnish children. Methods Panoramic radiographs of Finnish Caucasian healthy children from two generations (early: born 1981–1984; subsequent: born 1996–2008) were analysed. All developing teeth on the left maxilla and mandible as well as the third permanent molars were analysed following Demirjian’s classification. For each patient, dental age was calculated and compared with chronological age. Dental maturation patterns between the two groups were compared. Results The study included 200 Finnish Caucasian healthy children from two generations (early: aged 7–13 years; subsequent: aged 6–15 years). In the early generation, DAA underestimated the chronological age by a mean of 3.15 years. The underestimation was only 0.11 years in patients < 10 years, but 3.86 years in patients ≥ 10 years. In the subsequent generation, the dental age was overestimated by a mean of 0.34 years; by 0.40 years in patients < 10 years and by 0.08 years in patients ≥ 10 years. Conclusions The present DAA method is applicable to current Finnish children. Differences in dental development between two generations of Finnish children were detected.

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Correlation between Chronological Age, Cervical Vertebral Maturation and Fishman’s Skeletal Maturity Indicators in Central India Population

Orthodontic Journal of Nepal ◽

10.3126/ojn.v9i2.28415 ◽

2019 ◽

Vol 9 (2) ◽

pp. 52-56

Author(s):

Natasha Patil ◽

Neha Maheshwari ◽

Rohit Sharma ◽

Shashank Soni ◽

Ashish Kushwah

Keyword(s):

Skeletal Maturity ◽

Cervical Vertebrae ◽

Rank Correlation ◽

Cervical Vertebra ◽

Central India ◽

Growth Period ◽

Growth Spurt ◽

Chronological Age ◽

Spearman Rank Correlation Analysis ◽

Cervical Vertebral Maturation

Introduction: Skeletal maturity indicators are very important indicators when diagnosing and panning the treatment in growing population. Cervical Vertebrae Method (CVM) and Fishman’s Skeletal Maturity Indicators are two commonly used methods for the diagnosis and treatment planning. The aim of the study was to investigate the correlation between cervical vertebral maturation (CVM)and Fishman’s hand-wrist skeletal maturity indicator and chronological age by including subjects within the range of circumpubertal growth spurt in Central India. Materials & Method: One Twenty Five contemporary hand-wrist and lateral cephalometric radiographs from population of Central India were randomly selected and analyzed. All subjects were within the circumpubertal period i.e. female subjects were between 10 and 15 years of age, and the male subjects were between 12 and 17 years of age. The hand-wrist bone analysis was evaluated using the method developed by Fishman whereas cervical vertebra bone analysis was evaluated using the method developed by Baccetti and co-workers. These two methods and chronological age were correlated using the Spearman rank correlation analysis. Result: CVM was significantly correlated with hand-wrist maturation (r=0.8868). However low correlation was found between the CVM and chronological age( r =0.7139) and little correlation was found between the HWM and chronological age ( r =0.6892). Conclusion: CVM is a valid indicator of skeletal growth during the circumpubertal growth period and has a high correlation with the HWM for the Central India population. However chronological age is not suitable to measure skeletal maturity as shown by the low correlations found between the chronological age and both CVM and HWM.

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