scholarly journals Management of Luteal Phase Defect in Adolescent Girls

2012 ◽  
Vol 4 (1) ◽  
pp. 10-11 ◽  
Author(s):  
Indranil Dutta ◽  
Dilip Kumar Dutta

ABSTRACT Objective To find out the effect of dydrogesterone drug on menstral cycle of adolescent girl. Study design A total of 50 adolescent girl (16-19 years) who were suffering from irregular menstruation were recruited for this study from April 2008 to February 2009, at JNM Hospital, Kalyani, West Bengal, India. Results Menstrul cycle was found to be regular within 6 months of treatment along with the reduction of endometrial thickness. Conclusion Dydrogesterone was found to be safest drug to regularize menstrual cycle of adolescent girl suffering from menstrual irregularity due to luteal phase defect. How to cite this article Dutta DK, Dutta I. Management of Luteal Phase Defect in Adolescent Girls. J South Asian Feder Obst Gynae 2012;4(1):10-11.

1998 ◽  
Vol 116 (3) ◽  
pp. 1734-1737 ◽  
Author(s):  
Jorge Haddad Filho ◽  
Agnaldo Pereira Cedenho ◽  
Vilmon de Freitas

CONTEXT: Endometrial maturation, important in the diagnosis of infertile couples, has been evaluated since 1950 using the Noyes criteria. Nevertheless, there is no consensus regarding the most suitable period of the luteal phase for performing the biopsy. OBJETIVE: This study evaluated the correlation between the histological dating of two endometrial biopsies performed in the same menstrual cycle, on luteal phase days six and ten. DESIGN: Prospective study. SETTING: Human Reproduction Division of the Federal University of São Paulo, referral center. PATIENTS:Twenty-five women complaining of infertility had their menstrual cycles monitored by ultrasound and LH plasma levels, to obtain evidence of ovulation. PROCEDURES: Endometrial biopsies were performed on luteal phase days LH+6 and LH+10 (luteal phase day 1 = LH+1 = the day that follows LH peak). Dating was done according to morphometric criteria, in which an endometrium sample is considered out of phase if the minimum maturation delay is one day. On day LH+6, blood was drawn for plasma progesterone level determination. RESULTS: All patients had an ovulatory cycle (mean LH peak: 47.4 U/L; mean follicular diameter on LH peak day: 18.9 mm; mean endometrial thickness on LH peak day: 10.3 mm; mean plasma progesterone level on day LH+6: 14.4 ng/ml). 14 patients had both biopsies in phase; 5 patients had out of phase biopsies only on day LH+6; 3 had out of phase biopsies only on day LH+10 and 3 patients had out of phase biopsies on both days. McNemar's test showed no statistical difference between these data (p>33.36%). CONCLUSIONS: The correlation found between the endometrial datings suggests that biopsies performed on either of these two days are suitable for evaluation of endometrial maturation.


2016 ◽  
Vol 23 (07) ◽  
pp. 775-779
Author(s):  
Razia Tarique Qureshi ◽  
Fouzia Rahim ◽  
Gulfreen Haidar

Objectives: To determine the role of metformin in correcting the irregularity ofmenstrual periods and infertility due to PCO. Study Design: Descriptive observational study.Setting: Gynecology Department of PUMHS Nawabshah. Period: 4th February 2010 up toNovember 2011. Patients and methods: Total 329 patients had selected in this series, based onpresence of PCO on ultrasound with 2 or extra following criteria like oligomenorrhea, hirsutism,hyperandrogenism and reversed FSH: LH ratio. Other endocrinal reasons of female infertilityas Cushing syndrome, congenital adrenal hyperplasia, hyperprolectinemia and cases thyroiddisorder had excluded. After detailed history, Metformin was started with dose of 250mgonce a day initially then gradually adjusted to 500mg TD. Weight decreased was encouragedwith diet and the exercise. Cases assessed after six months for checking regularity of theirmenstrual cycle, fertility and the BMI change. Cases those not be success to conceive following6 months, than the ongoing criteria of clomiphene. Women those failed to conceive afteruses of clomiphene citrate, than metformin alone was sustained and fertility had re evaluatedon end of 1 year. Results: 329 cases had selected. Commonest menstrual irregularity wasoligomenorrhea with hypo menorrhea which is seen in 46% of patients. After six months ofmetformin treatment 82% cases assessed improvement of menstrual cycle, while 13% still haveoligomenorrhea. Results found significant (P<0.001) .BMI of all study patients was comparedprior and then treatment and significant results were found (P <0.001). After six months forfertility analysis, complete data was available from 117 patients only. Overall fertility rate was91.1%. Conclusion: Metformin is successful treatment of cases having PCOS.


2012 ◽  
Vol 4 (2) ◽  
pp. 110-112 ◽  
Author(s):  
Deepti Shrivastava ◽  
Shikha Joshi ◽  
Hariharan Chella

ABSTRACT Introduction Puberty menorrhagia is a real trouble among adolescent girls mostly due to problem in hypothalamic-pituitaryovarian axis. Aims and objectives To understand the various causative factors in puberty menorrhagia and to evaluate the role of hormones estrogens, progesterones or combination of both in controlling the excessive menstrual bleeding. Materials and methods It is a study conducted in the Department of Obstetrics and Gynecology at Acharya Vinoba Bhave Rural Hospital, JNMC, Sawangi from January 2009 to December 2010. Study included a total of 50 adolescent girls presenting with complains of menorrhagia. Results About 78% patients had menorrhagia due to immaturity of hypothalamic-pituitary-ovarian axis; 14% had polycystic ovarian disease and 8% had hypothyroidism. Out of 50 patients who were treated with hormones, 26 patients (52%) responded by the end of third month follow-up. Conclusion Majority of the patients showed good response to combined oral contraceptive pills (78%). How to cite this article Joshi S, Chella H, Shrivastava D. Study of Puberty Menorrhagia in Adolescent Girl in a Rural Set-up. J South Asian Feder Obst Gynae 2012;4(2):110-112.


Author(s):  
Devdatt Laxman Pitale

Background: Hyperprolactinemia may be associated with ovulatory dysfunction and resultant subfertility. Hyperprolactinemia affects the pulsatile release of GnRH, which in turn impairs the secretion of FSH and LH. It may also affect the endocrine activity of ovarian follicles, resulting into luteal phase defect and ovulatory dysfunction. Hyperprolactinemia may be associated with infertility in up to one-third of women undergoing infertility workup. Women with hyperprolactinemia are generally treated with dopamine receptor agonists to reduce serum prolactin levels and regularisation of menses. The aim of this study was to study the effectiveness of cabergoline therapy in hyperprolactinaemic infertility.Methods: This prospective study was performed from June 2017 to July 2018 in women with Hyperprolactinemic infertility attending the infertility clinic at INHS Patanjali. In this study, 20 women with hyperprolactinemic infertility who satisfied the inclusion and exclusion criteria were started on four week cabergoline therapy. The effectiveness of therapy was evaluated on the basis of normalization of prolactin levels, regularization of menses, reduction in galactorrhea, successful conception and adverse effects if any.Results: The women on Cabergoline therapy showed marked improvement in menstrual irregularity, near normal prolactin levels and reduced galactorrhea. After the four week Cabergoline therapy the frequency of galactorrhea and irregular menses was reduced in 8 (80%) and 14 (93.3) per cent, of women respectively. Successful conception was achieved in 17 (85%) women after regularization of menses with no any major adverse effects.Conclusions: This study shows the effectiveness of cabergoline therapy both on lowering the serum prolactin levels and successful Conception with no any major adverse effects. Cabergoline therapy is a cost effective and safe option in hyperprolactinaemic infertility.


Author(s):  
Shehnaz Shaikh

Introduction: Menstrual cycle or menstruation involved discharge of sanguinous fluid and a sloughing of uterine wall. In women menstruation occurs at regular intervals on an average of 28 days, although most women gave a history of regular intervals of 28 to 30 days. About 10% -15% of women showed cycle at the precise 28 ± 2 days intervals when menstrual calendar was utilized. Normally in young women in different phases of ovarian cycles the plasma levels of estrogen vary. Ovulation occurs in the first 12-13th day of menstrual cycle, which is termed estrogen surge and second occurs in mid-luteal phase. During mid cycle or follicular phase of menstrual cycle the plasma concentration of progesterone is very low about 0.9 ng/mL. its level starts rising owing to secretion from the granulose cells. During luteal phase progesterone level reaches its peak value of 18 ng/mL and its level fall to a minimum value toward the end of the cycle. Estrogen affects local and systemic vasodilation. The menstrual cycle envelops two fundamental stages, the follicular stage (FP) and the luteal stage (LP). The follicular stage can part advance into two substages; the early FP, which is characterised with moo concentrations of both the key hormones estrogen and progesterone; and the mid FP where estrogen is tall autonomously from progesterone. The LP is epitomized by tall concentration of both estrogen and progesterone. These two fundamental stages are isolated by a soak surge in luteinizing hormone activating ovulation. These recurrent changes are said to be frequency unsurprising while long time. Aim: The main aim of this study is to evaluate the Cardiorespiratory functions changes during different Phases of Menstrual Cycle.   Material and methods: In this study, 20 with normal weight, 20 with obese and 20 with overage were included and taken them as a sample size. In this study all the young women those were recruited as a sample size are unmarried, undergraduate female student with the between the age group of 18-22years, having regular 28+6 days menstrual cycle for at least last 6months prior to this study. For the collection of data all the participants were instructed to attend the physiology lab department during each of three different phases. Day-2 during menstrual phase, Day-7, during follicular phase and Day-22 during luteal phase and the following parameters were recorded as Anthropometric measurements, measuring of pulse rate and blood pressure and cardiac efficiency test. Result: In general, work out proficiency changed essentially amid the distinctive stages of the menstrual cycle with the most elevated amid luteal stage and least amid menstrualo stage. There was no critical contrast in impact test amid menstrual stage, follicular stage and luteal stage of menstrual cycle among three bunches of people. Conclusion: We have watched noteworthy increment in cardiac and respiratory proficiency within the luteal stage of the menstrual cycle in ordinary weight people. Lower wellness levels were watched in overweight and stout females. In this manner hone of customary work out and admissions of solid slim down which offer assistance in lessening the weight and in turn the BMI will offer assistance in improving the physical wellness of the people. Keywords: Cardiorespiratory, Menstrual cycle, expiratory blast test


Author(s):  
Ritu Gupta ◽  
Ravinder K Gupta ◽  
Vallabh Dogra ◽  
Himani Badyal

Objective: To study the various beliefs and problems regarding menstruation among adolescent girls living in rural border areas. Design- Prospective study. Setting- Pediatric outpatient clinic. Materials and methods- About 200 adolescent girls (11-19 years) living in rural border areas were enrolled for the study. These girls were asked about menarche, duration of the cycle, amount of blood loss and the various menstrual problems. They were also asked about the various beliefs and myths regarding menstruation. The girls having any illness affecting the menstrual cycle or those suffering from neuropsychiatric disorders were excluded from this study. Results- About 51% of the study population was in the age group 17-18 years. About 43.5% of girls attained menarche at the age of 10-12 years. About 51% of girls did not know about menstruation before menarche. Abdominal pain was the most common side effect seen in 41% of girls during menstruation. About 61% of girls considered themselves unclean during menstruation.  Twenty percent avoided schools, 20% avoided kitchen, 12% avoided temples while 10% stayed away from friends/ relatives. Only 33% of girls knew that menstruation stops temporarily after becoming pregnant. Twenty-two percent girls were using sanitary napkins while the rest used different types of clothes during the menstrual cycle. Conclusion- There is a dire need to educate girls regarding menstruation before menarche in the rural border areas. Every mother should discuss in a friendly way regarding various aspects of menstruation.


1975 ◽  
Vol 80 (1_Suppla) ◽  
pp. S20
Author(s):  
I. Gerhard ◽  
M. Röhrich ◽  
K. Klinga ◽  
B. Runnebaum
Keyword(s):  

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