scholarly journals Report of an unusually Huge Fibroepithelial Polyp managed with Diode Laser

2015 ◽  
Vol 6 (2) ◽  
pp. 52-55
Author(s):  
Rithesh Kulal ◽  
Shashwati Paul ◽  
Anuroopa Pudukulangara ◽  
Savita Sambashivaiah
Keyword(s):  
Diode Laser ◽  
Unusual Case ◽  
Histopathological Examination ◽  
Benign Tumors ◽  
Fibroepithelial Polyp ◽  
Neoplastic Lesions ◽  
Histological Variant ◽  
Malignant Lesions ◽  
Laser Excision ◽  
Functional Problems

ABSTRACT Fibromas are benign tumors that are composed of fibrous connective tissue. Fibroepithelial polyp (FEP) is a histological variant of fibroma that causes esthetic and functional problems. They may arise anywhere in the oral cavity, but are more commonly seen in the gingiva, tongue, and lip. Generally small and painless, they rarely continue to grow and might resemble other malignant lesions. This article reports an unusual case of a huge intraoral FEP that presented as a cauliflower-shaped lesion mimicking other neoplastic lesions. Laser excision was carried out following which histopathological examination revealed it as an inflamed FEP with ulceration. How to cite this article Paul S, Pudukulangara A, Kulal R, Sambashivaiah S. Report of an unusually Huge Fibroepithelial Polypmanagedwith Diode Laser. JHealth Sci Res 2015;6(2):52-55.

scholarly journals A histopathological review of nephrectomy specimens with an emphasis on pathological assessment of prognostic indicators in malignant lesions

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 492-501
Author(s):  
Shubha P. Bhat ◽  
Krishna Prasad H.V. ◽  
Rajeev T.P. ◽  
Kishan Prasad H.L. ◽  
Teerthanath Srinivas ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Malignant Tumour ◽  
Prognostic Indicators ◽  
Wilms Tumour ◽  
Malignant Tumours ◽  
Neoplastic Lesions ◽  
Kidney Lesion ◽  
Microscopic Features ◽  
Malignant Lesions ◽  
Pathological Assessment

Introduction and Aim: Various non-neoplastic and neoplastic lesions occur in the kidney. Pathological assessment of gross and microscopic features in nephrectomy specimens is essential for diagnosis and predicts the prognosis in malignant tumours. Materials and Methods: Case records of 46 nephrectomy specimens received between two-year periods were retrieved. Detailed gross and histopathological and immunohistochemical features were studied, and malignant tumours were analysed using CAP protocol. Results: Out of 46 nephrectomy specimens, 17 were non-neoplastic and 29 neoplastic. Males constituted 32 cases and females 14 cases. The commonest non-neoplastic kidney lesion was chronic pyelonephritis with hydronephrosis (29%). The mixed epithelial and stromal tumour was the frequently encountered benign tumour (50%). Renal cell carcinoma was the most common malignant tumour in adults (70%) and Wilms tumour in children (4%). Conclusion: Histopathological examination of nephrectomy specimens helps in diagnosing, staging, and planning the management.

scholarly journals A CLINICO -PATHOLOGICAL STUDY OF NEOPLASTIC AND NON-NEOPLASTIC OVARIAN LESIONS.

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Reena Verma ◽  
Dr. Kulwant Singh ◽  
Dr. Swaran Kaur ◽  
Dr. Rajiv Mahendru ◽  
Dr. Deepti Agarwal ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Abnormal Uterine Bleeding ◽  
Final Diagnosis ◽  
Reproductive Organs ◽  
Malignant Tumours ◽  
Patient Age ◽  
Patient Âgé ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Gross Examination

Background: Ovarian lesions constitute a complex group with varied clinical behaviour and pathology. The ovaries constitute the internal reproductive organs their lesions can present in childhood to postmenopausal age group Clinical, radiological and gross examination alone cannot distinguish benign from malignant lesions; hence, histopathological examination is needed for their diagnosis and management. Objectives: A Clinico -pathological analysis of non-neoplastic and neoplastic ovarian lesions. Materials and methods:  This descriptive study of one year comprised of 80 ovarian lesions diagnosed in the Department of Pathology, Bhagat Phool Singh Government medical college Sonipat. After thorough gross examination, representative bits were routinely processed and stained with H & E. Tumours were classified as per WHO classification. Results: Out of 80 ovarian lesions received, non-neoplastic lesions constituted 39% (31/80). Benign lesions constituted 45% (36/80) whereas borderline and malignant lesions constituted 5% (4/80) and 11.25% (9/80) respectively.  Among non-neoplastic lesions, follicular cysts (67.7%) constituted the majority followed by corpus luteal cysts and endometriotic cysts. Among neoplastic lesions majority of the tumours were of surface epithelial type (69.38%) followed by germ cell tumours (18.36%).  Bilateral lesions were seen in 17 (26.98%) patients while unilateral lesions were seen in 46 (73.01%) patients.  Patients age varied from 16 to 75 years. For non-neoplastic lesions, patient age varied from 16 to 61 years. For neoplastic lesions patient age ranged from 18-75 years with age range of 18-75 years for benign tumours and 26-66 years for malignant tumours. Abnormal uterine bleeding was the commonest clinical presentation of non-neoplastic lesions. Benign and malignant tumours were most commonly associated with pain abdomen. Conclusion: Ovarian lesions comprise of variety of non-neoplastic and neoplastic lesions. By knowing clinical data, gross features, we can narrow our differential diagnosis and reach to the final diagnosis.  So, early diagnosis and treatment definitely reduce the mortality from ovarian tumours. Keywords: Non-neoplastic, Benign, Malignant, Ovary, Lesions, Cysts, Tumours.

scholarly journals Clinical and histopathological correlation of breast lesions

2018 ◽  
Vol 6 (4) ◽  
pp. 1348
Author(s):  
Kavita Sharma ◽  
S. P. Vyas ◽  
Subhash Dhayal
Keyword(s):  
Invasive Carcinoma ◽  
Histopathological Examination ◽  
Breast Tumors ◽  
Mucinous Carcinoma ◽  
Malignant Tumour ◽  
Benign Tumors ◽  
Histopathological Study ◽  
Breast Lesions ◽  
Malignant Tumours ◽  
Neoplastic Lesions

Background: To study the histopathological features of neoplastic and non neoplastic lesions of breast.  To correlate the pathological findings with clinical parameters.Methods: We have studied total 170 cases of breast lesions over a period of two years in our institute. The specimens were received in histopathology section of our department. Detailed gross examination of specimens was done followed by fixation, thorough sampling, and tissue processing. The different lesions were studied by histopathological examination and analysed. Neoplastic lesions were classified according to the WHO classification.Results: Out of the 170 cases, 128 cases had neoplastic lesions and 41 cases had non-neoplastic lesions, and one case had coexistent neoplastic and nonneoplastic lesions. Out of the total 129 cases with neoplastic lesions, 76 cases had benign breast tumors, 51 cases had malignant breast tumors, and 2 cases had precursor lesions. Fibroadenoma was the most common benign tumour with 62 cases. Invasive carcinoma no special type was the most common malignant tumour with 43 cases. Special subtypes of invasive carcinoma found in our study were mucinous carcinoma (2 case). The most common nonneoplastic lesion was mastitis with 12 cases, followed by duct ectasia and fibrocystic change. There were 6 cases of gynaecomastia. All the tumors involved upper outer quadrant most frequently. The benign tumors were most frequent in second, third and fourth decades, malignant tumours were seen beyond 4th decade. The nonneoplastic lesions were common in 4th decade.Conclusions: Histopathological study is important in the management of breast lesions.

scholarly journals HISTOPATHOLOGICAL SPECTRUM OF SALIVARY GLAND LESIONS WITH CLINICAL CORRELATION

2020 ◽  
pp. 1-3
Author(s):  
Radhika Mucharla ◽  
Ravikanth Kotagiri
Keyword(s):  
Salivary Gland ◽  
Clinical Laboratory ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Final Diagnosis ◽  
Research Centre ◽  
Benign Tumors ◽  
Salivary Gland Tumours ◽  
Chronic Sialadenitis ◽  
Neoplastic Lesions

Salivary gland tumours account for 2-6.5% of all the neoplasms of the Head and Neck. Histopathology is most important in diagnosis of salivary gland tumors. AIMS and OBJECTIVES : To study age,sex and site distribution of various salivary gland lesions, to study the histomorphologic (gross &microscopic) aspect of these lesions to correlate clinical diagnosis with that of histopathologic features. MATERIALS AND METHODS: The study is conducted in the RAINBOW CLINICAL LABORATORY AND RESEARCH CENTRE, SIDDIPET during the period of September2018 to September 2020. Formalin fixed ,paraffin embedded sections and stained with hematoxylin and eosin slides were studied. RESULTS: Total number of specimens were 54. Out of these 39 were neoplastic (benign 70%,malignant 30%) and 15 were non neoplastic. Among the benign tumors majority are pleomorphic adenoma.Among the malignant tumors, mucoepidermoid carcinoma is the most common. Among the non neoplastic lesions chronic sialadenitis is most common. CONCLUSION: Histopathological examination of salivary gland lesions stands out to be the most important method in establishing the final diagnosis. It helps in differentiating non neoplastic and neoplastic lesions.

scholarly journals Diagnosis of upper gastrointestinal lesions by endoscopy and its correlation with histopathology

2020 ◽  
Vol 8 (2) ◽  
pp. 100-105
Author(s):  
Santhi Kiran D. ◽  
Nagarjuna Kumar Y. R.
Keyword(s):  
Gastrointestinal Tract ◽  
Diagnostic Procedure ◽  
Histopathological Examination ◽  
Wide Spectrum ◽  
Age Groups ◽  
Gastric Cavity ◽  
Gastrointestinal Lesions ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Upper Gastrointestinal

Background: A wide spectrum of lesions can be encountered in the upper gastrointestinal tract (GIT) especially the stomach or the gastric cavity. Endoscopy forms a crucial diagnostic procedure; it gives good diagnostic results in non-neoplastic lesions, endoscopy with biopsy is usually done in neoplastic lesions where the differentiation of benign and malignant lesions cannot be made always. Materials and Methods: This is a retrospective cum prospective study and the duration of this study was 4 yearsfrom January 2015 to December 2019 and the total number of endoscopic procedures performed was 3978. All patients with symptoms pertaining to the upper GIT where Upper Gastro-Intestinal Endoscopy (UGI Endoscopy) is useful in diagnosis were included in this study. All age groups and both the sexes were included. Biopsy was taken wherever there was an indication. Results: In this study, a total of 3978 endoscopies were done, out of which 2689 patients were males (67.6%) and 1289 were females (32.4%), youngest patient age in this study was 13 years and the oldest was 79 years. Most of the lesions were located in the gastric cavity (48% - 1909 cases), followed by esophagus (34%-1353 cases) and least among the three in the duodenum (18%- 716 cases). Out of the 3978 lesions, 134 cases were diagnosed as carcinoma on endoscopy and they were confirmed by histopathological examination. Conclusion: Endoscopy plays a very important role in the diagnosis of upper GIT lesions and it is incomplete without histopathological examination of biopsied tissue in cases of neoplastic lesions

scholarly journals Histopathological Spectrum in Pancreaticoduodenectomy Specimens: Fifteen Year Study from a Tertiary Care Centre in North India

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S60-S60
Author(s):  
S H Siddiqui ◽  
N Kumari ◽  
N Krishnani
Keyword(s):  
Indian Subcontinent ◽  
Tertiary Care ◽  
Pancreatic Head ◽  
North India ◽  
Cystic Neoplasm ◽  
Benign Tumors ◽  
Pancreatic Head Cancer ◽  
Epithelial Tumors ◽  
Neoplastic Lesions ◽  
Malignant Lesions

Abstract Introduction/Objective The periampullary region is histologically complex owing to the confluence of three different kinds of epithelia (duodenal, pancreatic, biliary) harbouring four types of cancers. Although anatomical proximity warrants a common surgical approach, overall survival depends largely on the type of surgical indication. Malignant epithelial tumors are the predominant indications, accompanied by a myriad of benign tumors and tumor-like lesions. We reviewed our archival pancreaticoduodenectomies to analyze the spectrum of these lesions. Methods All pancreaticoduodenectomy specimens received in Department of Pathology, from 2005–2019 (15 years) were analyzed for histological spectrum. Results A total of 786 pancreaticoduodenectomies were received with an overall M:F= 2.3:1 and age range 17–91 years. Of these, 94.4% were neoplastic (742 cases) and 5.6% were non-neoplastic. Benign neoplastic lesions (19 cases, 2.4%) included adenomyoma (7 cases, 0.9%), solid-cystic pseudopapillary tumor of pancreas (5 cases, 0.6%), intraductal papillary mucinous neoplasm (2 cases, 0.3%) and one case each of serous cystadenoma, mucinous cystic neoplasm, dermoid cyst, gangliocytic paraganglioma and Peutz-Jeghers polyp. Ampullary adenocarcinoma was the predominant malignant epithelial lesion (609 cases, 77.5%) followed by distal CBD cancer (43 cases, 5.5%), pancreatic head cancer (20 cases, 2.5%), neuroendocrine tumors (22 cases, 2.8%), carcinoma gallbladder (5 cases, 0.6%) and one case of ampullary adenosquamous carcinoma (0.1%). Non-epithelial tumors included 9 cases of GIST (1.1%), 3 of carcinosarcoma and one case each of leiomyosarcoma and lymphoma. Non-neoplastic lesions (3.2%) included 22 cases of chronic pancreatitis and one case each of xanthogranulomatous pancreatitis, lymphoplasmacytic slcerosing pancreatitis and xanthogranulomatous cholecystitis. Ectopic pancreas was rare (2 cases, 0.3%) and 16 cases (2%) were negative for any specific pathology. Conclusion This is the largest data on histological spectrum of pancreaticoduodenectomies from India. The malignant lesions form the major bulk (94%), however benign lesions also account for a substantial percentage of surgical indications. Among malignant lesions, ampullary cancers outreach far above pancreatic cancers in the Indian subcontinent.

scholarly journals A rare association in a patient with non-muscle invasive bladder cancer: ureteral fibroepithelial polyp and ipsilateral renal cell carcinoma: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Serkan Akan ◽  
Caner Ediz
Keyword(s):  
Renal Cell Carcinoma ◽  
Bladder Cancer ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Histopathological Examination ◽  
Left Kidney ◽  
Transitional Cell ◽  
Benign Tumors ◽  
Fibroepithelial Polyp

Abstract Background Fibroepithelial polyps located in the ureter constitute 2–6% of all benign tumors in the urinary system. Distinguishing these lesions from transitional cell carcinoma is essential to avoid unnecessary nephroureterectomy. Case presentation A 59-year-old asymptomatic caucasian male patient was enrolled in follow-up for Ta low-grade transitional cell bladder cancer 4 years ago in our clinic. A suspicious, solid, contrast-enhancing mass 15 × 9 mm in diameter in the anteromedial mid-section of the left kidney, which was causing minimal washout and largely located in the parenchyma, was reported as renal cell carcinoma on computed tomography during routine controls. In the excretory phase, soft-tissue densities of approximately 30 mm in length, which were located in the distal part of the left ureter at a distance of 40 mm from the ureterovesical junction, extending towards the lumen suggested a urethral carcinoma. Urothelial lesion was reported as fibroepithelial polyp after histopathological examination. Partial nephrectomy for the mass, which was reported as renal cell carcinoma in the left kidney, was performed in the first postoperative month. Histopathological examination revealed Fuhrman grade 1 papillary type renal cell carcinoma. No recurrence was observed in the first year after treatment. Conclusions Although our patient had a bladder transitional cell carcinoma and a suspicious renal cell carcinoma mass of 15 mm in the ipsilateral kidney, the patient was safeguarded from unnecessary nephroureterectomy early on by cross-sectional and endoscopic imaging of the ureter.

Premalignant and Malignant Lesions of the Heterotopic Pancreas in the Esophagus: a Case Report and Review of the Literature

2015 ◽  
Vol 24 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Jan Ulrych ◽  
Vladimir Fryba ◽  
Helena Skalova ◽  
Zdenek Krska ◽  
Tomas Krechler ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Unusual Case ◽  
Accurate Diagnosis ◽  
Heterotopic Pancreas ◽  
Premalignant Lesions ◽  
Resected Specimen ◽  
Review Of The Literature ◽  
Severe Dysphagia ◽  
Malignant Lesions

Heterotopic pancreas is a congenital pathology of the gastrointestinal tract, particularly rare in the esophagus. Both symptomatology and findings during preoperative examinations are non-specific and therefore do not often lead to an accurate diagnosis, which is usually revealed only by histopathological assessment of a resected specimen. We report an unusual case of a patient suffering from severe dysphagia caused by heterotopic pancreas in the distal esophagus with chronic inflammation and foci of premalignant changes. This article also reviews 14 adult cases of heterotopic pancreas in the esophagus previously reported in the literature, with the aim of determining the clinical features of this disease and possible complications including rare premalignant lesions and malignant transformation. Especially with regard to those complications, we suggest that both symptomatic and incidentally found asymptomatic lesions should be resected.

A prospective observational study on the effectiveness of risk of malignancy index score (RMI 3) in a tertiary care centre in Eastern India

2020 ◽  
Vol 11 (5) ◽  
pp. 54-60
Author(s):  
Apurba Mandal ◽  
Shibram Chattopadhyay ◽  
Sushanta Mondal ◽  
Arunava Biswas
Keyword(s):  
Ovarian Cancer ◽  
Adnexal Mass ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Ca 125 ◽  
Tertiary Care Centre ◽  
Gynecology And Obstetrics ◽  
Risk Of Malignancy ◽  
Malignant Lesions

Background: Adnexal mass is a common presentation in today’s gynecological practice. The incidence of ovarian cancer is increasing day by day and diagnosis is often difficult to be made pre operatively with inadequate surgical exploration is a regular occurrence. Aims and Objectives: To assess and validate the importance of RMI-3 score as pre-operative diagnostic tool of differentiating benign from malignant adnexal mass for starting first line therapy of ovarian cancer and to find out the incidences of ovarian malignancy among study population. Material and Methods: The study was conducted in the Department of Gynecology and Obstetrics on (n=115) patients attending GOPD and indoor with adnexal mass fulfilling the inclusion and exclusion criteria using purposive sampling technique. All the selected cases underwent ultrasonography and serum CA- 125 level estimation necessary for calculating RMI score. A score of >200 was taken as suggestive of malignancy and confirmatory diagnosis was performed by histopathological examination obtained from staging laparotomy of adnexal mass. The individual scores were then correlated with final outcomes with statistical analyses. Results: The study revealed benign ovarian tumors are more under 50 years (78.46%) and patients with normal BMI are diagnosed with maximum of malignancy (n = 28). History of tubal ligation carried less risk of malignancy (p<0.0001). Histologically malignant tumors found mostly in 71.4% postmenopausal group whereas 94.1% benign pathology were present in perimenopausal group and there is no association found between parity and histopathology (p=0.058). Bilateral (p=0.013), multilocular (p=0.000) tumors with solid areas (p<0.0001) and thick papillary projections (p<0.0001) had statistically significant association with malignant lesions. RMI score (>200) had more efficacy than serum CA-125 level (>46) in differentiating malignant lesions from benign one in terms of specificity (96% vs 83.87%) and positive predictive value (95% vs 79.17%). Conclusions: RMI-3 score is a simple, reliable and effective tool in differentiating benign from malignant adnexal masses thereby help in quick referral and management of cases with increase chances of survival of the patients.

scholarly journals Multimodality imaging review of focal renal lesions

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Jonathan Lyske ◽  
Rishi Philip Mathew ◽  
Christopher Hutchinson ◽  
Vimal Patel ◽  
Gavin Low
Keyword(s):  
Malignant Tumors ◽  
Multimodality Imaging ◽  
Lymphoproliferative Disease ◽  
Benign Tumors ◽  
Main Body ◽  
Imaging Features ◽  
Focal Lesions ◽  
Renal Lesions ◽  
Positron Emission ◽  
Neoplastic Lesions

Abstract Background Focal lesions of the kidney comprise a spectrum of entities that can be broadly classified as malignant tumors, benign tumors, and non-neoplastic lesions. Malignant tumors include renal cell carcinoma subtypes, urothelial carcinoma, lymphoma, post-transplant lymphoproliferative disease, metastases to the kidney, and rare malignant lesions. Benign tumors include angiomyolipoma (fat-rich and fat-poor) and oncocytoma. Non-neoplastic lesions include infective, inflammatory, and vascular entities. Anatomical variants can also mimic focal masses. Main body of the abstract A range of imaging modalities are available to facilitate characterization; ultrasound (US), contrast-enhanced ultrasound (CEUS), computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography (PET), each with their own strengths and limitations. Renal lesions are being detected with increasing frequency due to escalating imaging volumes. Accurate diagnosis is central to guiding clinical management and determining prognosis. Certain lesions require intervention, whereas others may be managed conservatively or deemed clinically insignificant. Challenging cases often benefit from a multimodality imaging approach combining the morphology, enhancement and metabolic features. Short conclusion Knowledge of the relevant clinical details and key imaging features is crucial for accurate characterization and differentiation of renal lesions.

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