scholarly journals A Cross-sectional Descriptive Study of Dermoscopy in various Nail Diseases at a Tertiary Care Center

2017 ◽  
Vol 1 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Manas Chatterjee ◽  
Shekhar Neema ◽  
Dipali Rathod ◽  
Meena Bhaskar Makhecha ◽  
Tishya Singh

ABSTRACT Introduction Nail diseases may often possess a challenge for the treating dermatologist, as they may primarily be affected without any skin involvement and sometimes may present with subtle changes which can be easily missed by the naked eye. The macroscopic nail changes can be assessed very well with a naked eye, however, the important minutiae may be assessed with a dermoscope. Aim To study the characteristic dermoscopic findings in various nail diseases. Materials and methods A total of 250 patients (males-130, females-120) with clinically evident nail diseases were enrolled in this cross-sectional descriptive study. After a thorough clinical examination, patients were subjected to dermoscopic examination of all 20 nails. Chi-square test or Fisher's exact test (in a very few patients of nail diseases) were used for statistical analysis, with a significance threshold of p < 0.05. Results Nail psoriasis (n = 45) was the commonest nail disease found in which the most common dermoscopic feature was circular punctate depressions (64.5%). Onychomycosis (n = 40) was the next common disease in which yellowish discoloration (100%) was commonly seen in all patients and rough scaly surface (100%) in the total dystrophic type. In pitted keratolysis (n = 19) transverse brown bands (57.9%) were most commonly seen as was the case in eczemas. Lichen planus (n = 14) was associated with longitudinal fissuring (64.3%) most commonly. Trachyonychia (n = 5) was associated with longitudinal fissuring (100%) in all cases. The most common dermoscopic feature of alopecia areata (n = 4) was circular punctate depressions (75%). Systemic scleroderma (n = 4) typically showed giant capillaries (75%) as the most common feature. Conclusion A meticulous search with the dermoscope, furnishes minuscule details of the nail unit that can be diagnostic of several nail diseases at an early stage before dystrophy sets in. However, further studies are required to validate these findings. Clinical significance Dermoscopy is a noninvasive complementary tool which aids in diagnosis of nail diseases more quickly and can also be used for monitoring the evolution, therapeutic response, and prognosis of these diseases. How to cite this article Rathod D, Makhecha MB, Chatterjee M, Singh T, Neema S. A Cross-sectional Descriptive Study of Dermoscopy in various Nail Diseases at a Tertiary Care Center. Int J Dermoscop 2017;1(1):11-19.

2021 ◽  
Vol 86 ◽  
pp. 97-102
Author(s):  
Hatice Yuksel ◽  
Gorkem Tutal Gursoy ◽  
Ebru Bilge Dirik ◽  
Safiye Gul Kenar ◽  
Hesna Bektas ◽  
...  

Author(s):  
Subrata Kumar Das ◽  
Saptadipa Das

<p class="abstract"><strong>Background:</strong> The aim was to evaluate the parameters of metabolic syndrome (MS) in patients of alopecia areata and to investigate the possibility of an existing relationship between MS and alopecia areata (AA).</p><p class="abstract"><strong>Methods:</strong> This cross-sectional observational study included 50 patients with AA who attended OPD of department of dermatology at a tertiary care center during a period of 1 year. Clinical and laboratory parameters were noted in each patient.<strong></strong></p><p class="abstract"><strong>Results:</strong> This study included 50 patients with AA (33 males and 17 females). In the present study maximum number of patients belonged to the age group 20-30 years with 23 patients, followed by 30-40 years with 17  patients. Most of the study subjects, 17 were college students and number of employees were 15. Out of 50 patients 44  had patch(es) and 2 patient had alopecia totalis. In this study out of 50 patients, 38 had mild AA, 7 had AA and 5 patients had severe AA. No significant derangement of clinical and laboratory parameters of MS observed in patients of AA.</p><p class="abstract"><strong>Conclusions:</strong> In the present study we did not observe any significant derangement of clinical and laboratory parameters of  MS  in patients of alopecia areata.</p>


2021 ◽  
Vol 12 (2) ◽  
pp. 120-129
Author(s):  
Romita Bachaspatimayum ◽  
Zamzachin Guite ◽  
Thangjam Bijayanti Devi

Background: Genital ulcers are defined as breaches in the continuity of the genital mucosa and/or skin. Sexually transmitted infections (STIs) that cause genital ulcer disease (GUD) are syphilis, chancroid, donovanosis, lymphogranuloma venereum (LGV), and herpes genitalis. This study aimed to investigate the clinical and laboratory profiles of STI-related genital ulcers. Materials and Methods: A cross-sectional two-year study was conducted on patients attending the Outpatient Department of Dermatology, Venereology and Leprosy in a tertiary care center in northeastern India. Selected were 95 patients who presented themselves with STI-related genital ulcers. Detailed history taking and examination were conducted with basic tests to assist the diagnosis. Results: The male-to-female ratio was 3.32:1, and the most common site was the glans and prepuce in males (28.77%) and the labia majora and minora in females (36.36%). 96.84% of patients had superficial ulcers. The KOH mount was positive in 26 patients. The Tzanck smear was positive in 31 patients. RPR was positive in four. HIV was positive in eleven. Herpes genitalis (96.84%) was the most common GUD. Mixed STIs were attested in 41.05% of patients. Conclusion: GUD can take various forms of presentation. The available laboratory tests should be utilized. The possibility of mixed infections should always be kept in mind.


2018 ◽  
Vol 21 (2) ◽  
pp. 169-176 ◽  
Author(s):  
Annemarie Bösch ◽  
Julia Wager ◽  
Boris Zernikow ◽  
Ralf Thalemann ◽  
Heidi Frenzel ◽  
...  

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