scholarly journals Ketamine exhibits anti-gastric cancer activity via induction of apoptosis and attenuation of PI3K/Akt/mTOR

2020 ◽  
Vol 16 (5) ◽  
pp. 1140-1149
Author(s):  
Shiling Zhao ◽  
Lin Shao ◽  
Yingwei Wang ◽  
Qingtao Meng ◽  
Jinning Yu
2017 ◽  
Vol 2017 ◽  
pp. 1-11
Author(s):  
Chen Yu ◽  
Ai-Jun Ji ◽  
Jian-Wei Lu ◽  
Shi-Jia Liu ◽  
Yu Sun

San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) or a combination of SLPE and 5-Fu. Our results indicate that the inhibition of tumor growth by SLPE might be due to a block in the cell cycle and the induction of apoptosis. These results suggest that SLPE might be useful in the treatment of gastric cancer.


2018 ◽  
Vol 33 (2) ◽  
pp. 111-117 ◽  
Author(s):  
Reza Nasr ◽  
Hadi Hasanzadeh ◽  
Ali Khaleghian ◽  
Abdolvahab Moshtaghian ◽  
Alireza Emadi ◽  
...  

Heliyon ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. e03561 ◽  
Author(s):  
Oyebamiji Abel Kolawole ◽  
Fadare Olatomide A ◽  
Semire Banjo

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