Bioactive Natural Medicinal Plants in South Indian Western Ghats and Their Pharmacological Importance

2020 ◽  
Vol 6 (2) ◽  
pp. 62-69
Author(s):  
M. Tamizharasi ◽  
R. Rajila ◽  
D. Beula Shiny ◽  
J. Vijila Jasmin ◽  
T. Kumaran

Awareness of traditional knowledge and medicinal plants can play a key role in the utilization and discovery of natural plant resources. Plants became the basis of medicine system throughout the world for thousands of years and continue to provide mankind with new remedies. Researchers generally agree that natural products from plants and other organisms have been the most consistently successful source for ideas for new drugs. The world health organization estimates that 80% of the population living in the developing countries relies exclusively on traditional medicine for their primary health care. More than half of the world's population still relies entirely on plants for medicines, and plants supply the active ingredients of most traditional medical products. The review shows the south Indian medicinal plant products has been used by people to treat various health ailments.

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1278-1285
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Ibrahim Sbai El Otmani ◽  
Youssef Khayati ◽  
Amal Ait Haj Said

The new SARS-CoV-2 belonging to the coronaviruses family has caused a pandemic affecting millions of people around the world. This pandemic has been declared by the World Health Organization as an international public health emergency. Although several clinical trials involving a large number of drugs are currently underway, no treatment protocol for COVID-19 has been officially approved so far. Here we demonstrate through a search in the scientific literature that the traditional Moroccan pharmacopoeia, which includes more than 500 medicinal plants, is a fascinating and promising source for the research of natural molecules active against SARS-CoV-2. Multiple in-silico and in-vitro studies showed that some of the medicinal plants used by Moroccans for centuries possess inhibitory activity against SARS-CoV or SARS-CoV-2. These inhibitory activities are achieved through the different molecular mechanisms of virus penetration and replication, or indirectly through stimulation of immunity. Thus, the potential of plants, plant extracts and molecules derived from plants that are traditionally used in Morocco and have activity against SARS-CoV-2, could be explored in the search for a preventive or curative treatment against COVID-19. Furthermore, safe plants or plant extracts that are proven to stimulate immunity could be officially recommended by governments as nutritional supplements.


2020 ◽  
Vol 10 (7) ◽  
pp. 2605 ◽  
Author(s):  
Christian Lienhardt ◽  
Mario C. Raviglione

The World Health Organization (WHO) End Tuberculosis (TB) Strategy has set ambitious targets to reduce 2015 TB incidence and deaths by 80% and 90%, respectively, by the year 2030. Given the current rate of TB incidence decline (about 2% per year annually), reaching these targets will require new transformational tools and innovative ways to deliver them. In addition to improved tests for early and rapid detection of TB and universal drug-susceptibility testing, as well as novel vaccines for improved prevention, better, safer, shorter and more efficacious treatments for all forms of TB are needed. Only a handful of new drugs are currently in phase II or III clinical trials, and a few combination regimens are being tested, mainly for drug-resistant TB. In this article, capitalising on an increasingly rich medicine pipeline and taking advantage of new methodological designs with great potential, the main areas where progress is needed for a transformational improvement of treatment of all forms of TB are described.


Author(s):  
Susan B. Rifkin

In 1978, at an international conference in Kazakhstan, the World Health Organization (WHO) and the United Nations Children’s Fund put forward a policy proposal entitled “Primary Health Care” (PHC). Adopted by all the World Health Organization member states, the proposal catalyzed ideas and experiences by which governments and people began to change their views about how good health was obtained and sustained. The Declaration of Alma-Ata (as it is known, after the city in which the conference was held) committed member states to take action to achieve the WHO definition of health as “state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.” Arguing that good health was not merely the result of biomedical advances, health-services provision, and professional care, the declaration stated that health was a human right, that the inequality of health status among the world’s populations was unacceptable, and that people had a right and duty to become involved in the planning and implementation of their own healthcare. It proposed that this policy be supported through collaboration with other government sectors to ensure that health was recognized as a key to development planning. Under the banner call “Health for All by the Year 2000,” WHO and the United Nations Children’s Fund set out to turn their vision for improving health into practice. They confronted a number of critical challenges. These included defining PHC and translating PHC into practice, developing frameworks to translate equity into action, experiencing both the potential and the limitations of community participation in helping to achieve the WHO definition of health, and seeking the necessary financing to support the transformation of health systems. These challenges were taken up by global, national, and nongovernmental organization programs in efforts to balance the PHC vision with the realities of health-service delivery. The implementation of these programs had varying degrees of success and failure. In the future, PHC will need to address to critical concerns, the first of which is how to address the pressing health issues of the early 21st century, including climate change, control of noncommunicable diseases, global health emergencies, and the cost and effectiveness of humanitarian aid in the light of increasing violent disturbances and issues around global governance. The second is how PHC will influence policies emerging from the increasing understanding that health interventions should be implemented in the context of complexity rather than as linear, predictable solutions.


2014 ◽  
Vol 2014 ◽  
pp. 1-20 ◽  
Author(s):  
Si-Yuan Pan ◽  
Gerhard Litscher ◽  
Si-Hua Gao ◽  
Shu-Feng Zhou ◽  
Zhi-Ling Yu ◽  
...  

In recent years, increasing numbers of people have been choosing herbal medicines or products to improve their health conditions, either alone or in combination with others. Herbs are staging a comeback and herbal “renaissance” occurs all over the world. According to the World Health Organization, 75% of the world’s populations are using herbs for basic healthcare needs. Since the dawn of mankind, in fact, the use of herbs/plants has offered an effective medicine for the treatment of illnesses. Moreover, many conventional/pharmaceutical drugs are derived directly from both nature and traditional remedies distributed around the world. Up to now, the practice of herbal medicine entails the use of more than 53,000 species, and a number of these are facing the threat of extinction due to overexploitation. This paper aims to provide a review of the history andstatus quoof Chinese, Indian, and Arabic herbal medicines in terms of their significant contribution to the health promotion in present-day over-populated and aging societies. Attention will be focused on the depletion of plant resources on earth in meeting the increasing demand for herbs.


2009 ◽  
Vol 51 (5) ◽  
pp. 247-253 ◽  
Author(s):  
José Angelo L. Lindoso ◽  
Ana Angélica B.P. Lindoso

Poverty is intrinsically related to the incidence of Neglected Tropical Diseases (NTDs). The main countries that have the lowest human development indices (HDI) and the highest burdens of NTDs are located in tropical and subtropical regions of the world. Among these countries is Brazil, which is ranked 70th in HDI. Nine out of the ten NTDs established by the World Health Organization (WHO) are present in Brazil. Leishmaniasis, tuberculosis, dengue fever and leprosy are present over almost the entire Brazilian territory. More than 90% of malaria cases occur in the Northern region of the country, and lymphatic filariasis and onchocerciasis occur in outbreaks in a particular region. The North and Northeast regions of Brazil have the lowest HDIs and the highest rates of NTDs. These diseases are considered neglected because there is not important investment in projects for the development of new drugs and vaccines and existing programs to control these diseases are not sufficient. Another problem related to NTDs is co-infection with HIV, which favors the occurrence of severe clinical manifestations and therapeutic failure. In this article, we describe the status of the main NTDs currently occurring in Brazil and relate them to the HDI and poverty.


2021 ◽  
Vol 2 (02) ◽  
pp. 94-103
Author(s):  
Maria Bibi ◽  
Samiullah Khan ◽  
Attiq-Ur-Rehman Kakar ◽  
Naqeebullah Khan ◽  
Abdul Hakeem Tareen ◽  
...  

Background: Medicinal plants have been used to treat various diseases for several years throughout the world. Xylanthemum macropodum is a medicinal plant with a vast application as a home remedy in Balochistan. Objective: The current study was conducted to determine the levels of essential and non-essential elements in Xylanthemum macropodum collected from Quetta (Balochistan, Pakistan). Methods: Analysis was conducted for eleven elements by using atomic absorption spectrophotometer and flame photometer. Results: The essential and non-essential elements that were detected in Xylanthemum macropodum are K, Na, Ca, Fe, Cu, Co, Ni, Mn, Cr, Cd and Pb, respectively. The result of the concentration of determined elements are in the order of K> Na> Ca> Fe> Cu> Co> Ni> Mn> Cd> Cr> Pb in Xylanthemum macropodum 3000> 1600> 790.25> 92.36> 85.31> 49.24> 40.94> 20.94> 6.655> 1.61> 1.18 µg/g respectively. Conclusions: Mn, Na and Pb were found within the permissible limit given by World Health Organization, while Ca, Cu, Fe, Ni, Cd and Cr were beyond the permissible limits. However, there is no permissible limit for K and Co.


Author(s):  
Onder Otlu ◽  
Ceyhun Bereketoglu ◽  
Tugba Raika Kiran ◽  
Aysun Bay Karabulut

The 2019-nCoV (new Corona Virus) outbreak was announced by the World Health Organization (WHO), the International Emergency Public Health Organization, on January 30, 2020, and WHO reported the 2019-nCoV pathogen to SARSCoV-2 and Corona virus Disease 2019 on 12 February. (COVID2019). COVID-19 was officially recognized as a Pandemic by WHO on March 11, 2020. Plants have been used all over the world as traditional medicine for centuries to treat many chronic infections, including viral diseases. In recent years, scientists have been trying to verify the potential of functional compounds to protect human health and cure diseases with their research on functional and nutraceutical foods. Traditional medicinal plants have a long history supported by many researches such as maintaining a healthy life, toxins taken in daily life, fighting and preventing diseases, and longevity. Studies on the antiviral, antiinflammatory and antioxidant properties of ethnomedical plants and natural phytochemicals can be considered as a great potential drug source against various ailments as well as Covid-19 treatment. Based on this study, plant extracts increase immunity with the increase in the number of white blood cells and lymphocytes in viral infections such as Covid-19, which can lead to fatal consequences, regulating the production and release of proinflammatory cytokines, showing an anti-inflammatory effect with a decrease in the C-reactive protein and erythrocyte sedimentation rate, It appears to have a positive effect such as interfering with the development and potential antiviral agent activity. In this study, phytochemicals and effects associated with COVID-19 infection were reviewed.


Author(s):  
Richard D.W. Hain ◽  
Satbir Singh Jassal

Communication skills amongst professionals all centre on the basic ideology of teamworking. The World Health Organization affirms that primary health should involve all related sectors working together, including education and social services, in addition to health care, and that efforts should be made to coordinate these sectors. This chapter explores how best to ensure effective communication in the care of a terminally ill child through team theory and by examining the challenges of teamwork. General guidance for establishing successful teamwork is also given.


2020 ◽  
Vol 8 ◽  
Author(s):  
Luiza F. O. Gervazoni ◽  
Gabrielle B. Barcellos ◽  
Taiana Ferreira-Paes ◽  
Elmo E. Almeida-Amaral

Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the World Health Organization as a neglected tropical disease that is responsible for millions of deaths worldwide. Although there are many possible treatments for leishmaniasis, these treatments remain mostly ineffective, expensive, and long treatment, as well as causing side effects and leading to the development of resistance. For novel and effective treatments to combat leishmaniasis, many research groups have sought to utilize natural products. In addition to exhibiting potential as therapeutic compounds, natural products may also contribute to the development of new drugs based on their chemical structures. This review presents the most promising natural products, including crude extracts and isolated compounds, employed against Leishmania spp.


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