scholarly journals HISTOLOGICAL CONSEQUENCES OF CONSUMPTION OF ENERGY DRINK ON RENAL TUBULES

2021 ◽  
Vol 71 (5) ◽  
pp. 1736-40
Author(s):  
Ammara Rasheed ◽  
Imtiaz Aslam ◽  
Raafea Tafweez ◽  
Muhammad Rizwan Bashir Kiani ◽  
Muhammad Kamran Ameer ◽  
...  
Keyword(s):  
Body Weight ◽  
Energy Drink ◽  
Albino Rats ◽  
P Value ◽  
Renal Tubules ◽  
Chi Square ◽  
Qualitative Variables ◽  
Chi Square Test ◽  
The Mean ◽  
Post Hoc

Objective: To investigate the outcomes of energy drink on renal tubules of albino rats. Study Design: Laboratory-based experimental study. Place and Duration of Study: King Edward Medical University, Lahore from Aug 2018 to Dec 2019. Methodology: Group A and B were experimental groups received 1.5ml/kg and 2.2ml/kg body weight of energy drink, respectively. Group C received 1ml/kg body weight of distilled water. Comparison among groups was made by applying One-Way ANOVA for quantitative variables. Tukey’ test was used for post hoc analysis. For qualitative variables, chi-square test was applied to make comparison among groups Results: The mean initial and final weight of animals was around 152.7 ± 5.3g and 171.9 ± 5.1g, respectively. The mean paired kidney weight, relative tissue weight index, length and width of kidneys for all three groups were found insignificant. Microscopic examination showed tubular vacuolization in groups A and B showing p-value of 0.027. Conclusion: Consumption of energy drinks results in histopathological injury of epithelial cells of renal tubules.

scholarly journals Role of Early Tracheostomy in the Management of Severe Head Injury

2019 ◽  
Vol 23 (3) ◽  
pp. 188-192
Author(s):  
ABDUL MAJID ◽  
MUHAMMAD FAROOQ ◽  
MUHAMMAD SHAKIR ◽  
ZUBAIR MUSTAFA KHAN ◽  
SAJID IQBAL
Keyword(s):  
Controlled Trial ◽  
Head Injuries ◽  
P Value ◽  
Chi Square ◽  
Early Tracheostomy ◽  
Qualitative Variables ◽  
Chi Square Test ◽  
The Mean ◽  
Complications And Mortality

Objective: The objective of this study was to compare the role of early and late tracheostomy in patients presenting with severe head injuries.Material and Methods: This randomized controlled trial study was conducted in the department of neurosurgery, Lahore General Hospital Lahore from March 2018 to August 2018, after taking approval from the ethical committee. A total of one hundred and thirty patients was divided randomly into early (within three days) and late(after three days) tracheostomy groups. After tracheostomy, data regarding acute physiology, age and chronic health evaluation II (APACHE II), the total number of days since ventilation, tracheostomy, weaning, discharge from ICU and hospital, complications and mortality were noted. All the data was entered and analyzed with SPSS23.0. Quantitative variables were presented as mean and standard deviation, qualitative variables were presented as numbers and percentage. The Chi-square test was applied. A p-value of ≤0.05 was considered significant.Results: The mean age of the patients was 33.13 ± 2.53 years. There were 84 males (64.61%) and 46 females (35.38%) in the study. The duration of mechanical ventilation, ICU stay and stay in hospital for early and late tracheostomy groups were 25.68 ± 2.94 vs. 33.37 ± 3.32 days, 29.42 ± 2.97 vs. 38.54 ± 3.80 days and 37.20 ± 2.98 vs. 47.15 ± 3.84 days respectively. Four patients (3.08%) and seven patients (5.38%) suffered from mortality.Conclusion: Early tracheostomy among the patients presenting with severe head injuries was associated with a better outcome than late tracheostomy.

Comparison of Early Versus Delayed Showering on Post-Operative Wound Infections

2021 ◽  
Vol 11 (03) ◽  
pp. 125-128
Author(s):  
Salman Habib Abbasi ◽  
Abdul Basit ◽  
Muhammad Farooq ◽  
Fazal Hussain Shah
Keyword(s):  
Controlled Trial ◽  
P Value ◽  
Continuous Variables ◽  
Chi Square ◽  
Surgical Wounds ◽  
Qualitative Variables ◽  
Chi Square Test ◽  
Surgery First ◽  
The Mean ◽  
Clean Contaminated

Objectives: To compare frequency of SSIs with and without early showering after clean and clean contaminated surgical wounds. Study Design and Setting: Randomized controlled trial was conducted at Department of Surgery. HIT Hospital, Taxila from June 2020 to December 2020. Methodology: A total of 130 participants were recruited after taking informed consent. After clean and clean-contaminated surgery, first group was subjected to early showering (48 hours after surgery) while second group was not allowed showering until removal of stiches. Both groups were compared in terms of SSIs. Data was entered into SPSS version 25. The mean and standard deviation were used for the expression of continuous variables while frequency and proportion were used for qualitative variables. Both groups were compared by independent sample t test and chi square test. A p value of <0.05 was considered statistically significant. Results: The mean age of the patients was 39.92 ± 11.42 years and there was male gender dominancy i.e. 74 (56.9%) were males while 56 (43.1%) were females. Clean surgeries were 81 (62.3%) and clean-contaminated proportion was 49 (37.7%). Collectively, 12 (9.2%) patients developed SSIs during clinical followup. There was no difference between groups in terms of age, gender, and wound types (p values 0.680, 0.157 and 0.587 respectively). In shower group, 3 (4.6%) and in nonshower group, 9 (13.8%) patients developed SSIs (p value 0.069). Conclusion: Early postoperative showering can be implemented safely in clean and clean contaminated surgical wounds to minimize SSIs. The results should be evaluated in large RCTs

scholarly journals Effect of ondansetron on spinal induced hypotension in caesarean deliveries

2020 ◽  
Vol 8 (4) ◽  
pp. 193-199
Author(s):  
Pujan Balla ◽  
Anil Shrestha ◽  
Ninadini Shrestha ◽  
Navindra Bista ◽  
Moda Nath Marhatta
Keyword(s):  
Spinal Anesthesia ◽  
Elective Caesarean Section ◽  
P Value ◽  
Chi Square ◽  
Induced Hypotension ◽  
Intergroup Comparison ◽  
Chi Square Test ◽  
The Mean ◽  
Student’S T ◽  
Student’S T Test

Background: Spinal anesthesia is the preferred technique of anesthesia employed for caesarean sections. However, it is very often complicated by hypotension. Different drugs and techniques have been used to prevent the hypotension induced by spinal anesthesia. In this study, the effect of ondansetron on the prevention of hypotension after spinal anesthesia was evaluated. Objectives: To determine the effect of prophylactic ondansetron on prevention of spinal induced hypotension in elective caesarean section. Methodology: Eighty-six parturients planned for elective caesarean deliveries were randomized into two groups of 43 each. Group O received Ondansetron 4 mg (4 ml) and Group S received Normal Saline (4 ml) intravenously 10 minutes prior to spinal anesthesia. Blood pressure, heart rate, phenylephrine requirements, occurrence of nausea and vomiting and APGAR scores of neonates were compared between the groups. Hemodynamic data was analyzed using Student’s t-test for intergroup comparison and ANOVA was used for intragroup comparison. Categorical data was analyzed using Pearson Chi-Square test. For all determinants, p-value <0.05 was considered significant. Results: Occurrence of hypotension in Group O (20.9 %) was significantly lower than in Group S (72.1%) (p < 0.05). The mean arterial pressure was significantly higher in Group O at 2, 6, 8, 12 and 14 minutes (p < 0.05). The use of phenylephrine (37.21 mcg vs. 146.51 mcg, p < 0.05) and occurrence of nausea (11.6%, vs. 41.9% p < 0.002) was significantly lower in ondansetron group. Conclusion: Ondansetron is effective in preventing spinal induced hypotension in elective caesarean sections.

scholarly journals Diagnostic, therapeutic and prognostic aspects of uterine synechiae managed by hysteroscopy in the gyanecological endoscopic surgery and human reproductive teaching hospital

2017 ◽  
Vol 7 (1) ◽  
pp. 56
Author(s):  
Etienne Belinga ◽  
Isidore Tompeen ◽  
Claude Cyrille Noa Ndoua ◽  
Junie Metogo Ntsama ◽  
Sandrine Mendibi ◽  
...  
Keyword(s):  
Past History ◽  
Cross Sectional Study ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Qualitative Variables ◽  
Preoperative Diagnostic ◽  
Chi Square Test ◽  
Human Reproductive ◽  
History Of

Background: Uterine synechiae refers to a total or partial union of the inner walls of the uterus resulting from endometrial trauma. It is a cause of reproductive failure. Until now, synechia was not optimally treated and has remained understudied in Cameroon. Objective of present study was to Evaluate the diagnostic, therapeutic and prognostic aspects of uterine synechiae treated by hysteroscopy.Methods: We conducted a descriptive cross-sectional study with an analytical component from January 1st 2015 to July 31st 2017 at Yaounde. All patients diagnosed with uterine synechiae and treated with hysteroscopy were our sample. Sampling was consecutive. The chi-square test was used for the comparison of qualitative variables and Fisher's test for ANOVA variance analysis. The comparison of the averages was made by the Student's test. P-value less than 0.05 was considered as statistically significant.Results: Hysteroscopies were indicated for uterine synechiae in 14.50%. Nulliparous were 56.67%. A history of curettage/aspiration was present in 66.66%. All of the patients had a form of infertility and 83.33% had menstrual disorders. Hysterosalpingography showed a better sensitivity (88%). After hysteroscopic treatment, 63.30% had a complete anatomical restitution. There is a significant correlation between the stage of severity of synechia and anatomical restitution (p=0.008; Spearman correlation coefficient=-0.477).Conclusions: Uterine synechiae represent one-sixth of all indications for hysteroscopy and present clinically as menstrual disorder associated with infertility. A past history of uterine curettage is common. Hysterosalpingography has a better preoperative diagnostic sensitivity. Hysteroscopy allows optimal treatment.

scholarly journals Effect of Red Bull on Histology of Renal Mesangium

2021 ◽  
Vol 25 (1) ◽  
pp. 77-82
Author(s):  
Ammara Rasheed ◽  
Mohtasham Hina ◽  
Muhammad Rizwan Bashir Kiani ◽  
Raafea Tafweez ◽  
Imtiaz Aslam ◽  
...  
Keyword(s):  
Body Weight ◽  
Controlled Trial ◽  
Energy Drink ◽  
Male Rats ◽  
P Value ◽  
Vascular Congestion ◽  
Group A ◽  
The Mean ◽  
Medical University ◽  
Red Bull

Objective: To determine the consequences of energy drink (Red bull) on renal mesangium of albino rats.Materials and Methods: This study was carried out at the Anatomy Department of King Edward Medical University, Lahore, from August 2018 to December 2019. It was an experimental randomized controlled trial. Total 90 adult albino male rats, 8-12 weeks old, weighing 130 to 160 grams were taken. Healthy animals were included. Rats were divided into three groups Group A and B experimental groups received 1.5ml/kg and 2.2ml/kg body weight of red bull energy drink, respectively. Group C received 1ml/kg body weight of distilled water.Results: The mean initial and final weight of animals was around 150g and 170g, respectively. The mean paired kidney weight and relative tissue weight index for all three groups were found insignificant. Microscopic examination showed mesangial hypercellularity and vascular congestion in renal cortex of groups A and B, none in group C. These were significant among two experimental groups with a p-value less than 0.001.Conclusion: It was found that the use of energy drinks induces histopathological changes in the renal mesangium.

scholarly journals FACTORS CAUSING RECURRENCE OF INFECTION IN THE CORNEAL GRAFT AFTER THERAPEUTIC PENETRATING KERATOPLASTY

2021 ◽  
pp. 5-6
Author(s):  
Rohit Rohit ◽  
Lokesh Kumar Singh
Keyword(s):  
Risk Factor ◽  
Social Services ◽  
Corneal Graft ◽  
P Value ◽  
Main Risk Factor ◽  
Chi Square ◽  
Department Of Ophthalmology ◽  
Qualitative Variables ◽  
Chi Square Test ◽  
One Year

Aim:-The aim of this study is to analyse the factors causing recurrence of infection in the corneal graft after therapeutic penetrating keratoplasty.Material and Methods:- This study was conducted at Upgraded Department of Ophthalmology, SVBPH,Meerut. This institution performs 120 keratoplasty procedures per year on an average. The study was conducted for a period of one year & 25 patients had reinfection and those who presented with reinfection constituted the sample size complete enumeration.The data thus obtained was compiled and analysed using Statistical Package for Social services (SPSS vs 20). The qualitative variables were analyzed by using frequencies and The qualitative variables were analyzed by using frequencies & percentages & chi square test was used as test of significance.The quantitative variables were presented as measures of central tendency and dispersion. A p value of less than 0.05 was considered as statistically significant Results Initial fungal etiology was the main risk factor for the recurrence of microbial keratitis after TPK in (24%) of the cases followed by persistent epithelial defects (16%),Initial bacterial etiology (12%), Lid abnormalities (8%) ,contact lens use (8%), Secondary ocular hypertension (8%), prior rejection episodes(8%), initial viral etiology (4%) ,peripheral ulcerative keratitis (8%) & suture related problems(4%). Conclusion:- .This study has shown that Fungal keratitis was the main reason for the initial TPK & initial Fungal aetiology was the main risk factor for the reinfection after TPK

scholarly journals Inflammatory markers in Covid-19 Patients: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Golnaz Vaseghi ◽  
Marjan Mansourian ◽  
Raheleh Karimi ◽  
Kiyan Heshmat-Ghahdarijani ◽  
Paria Rouhi ◽  
...  
Keyword(s):  
Inflammatory Markers ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
P Value ◽  
Chi Square ◽  
Effect Model ◽  
Chi Square Test ◽  
History Of ◽  
The Mean

AbstractIntroductionDiagnosis of COVID-19 is based on clinical manifestation, history of exposure, positive findings on chest CT and laboratory tests. It has been shown that inflammation plays a role in pathogenesis of COVID-19.MethodWe used the necessary transformations to convert the median and IQR to mean and SD Random-effect model using Der Simonian, and Laird methods was used if heterogeneity between studies was significant, the homogeneity among studies was assessed with I2 Statistic, values above 50%, and for the chi-square test, P-values <0.1 was supposed statistically significantResultsTwelve studies were included in the analysis that all of which were conducted in China in the year 2020. The result of combining 12 articles with 772 participants showed that the pooled estimate of the mean of lymphocyte with 95% CI was (Mean: 1.01; 95% CI (0.76-1.26); p-value<0.001). About WBC the pooled result of 9 studies with 402 participants was (Mean: 5.11; 95% CI (3.90-6.32); p-value<0.001) Also the pooled mean estimate of 9 studies with 513 patients for the ratio of Neutrophil/lymphocyte was (Mean: 3.62; 95% CI (1.48-5.77); p-value=0.001). The pooled mean from the combination of 7 studies with 521 patients on CRP was (Mean: 28.75; 95% CI (8.04-49.46).ConclusionInflammatory Markers increase in patients with Covid-19, which can be a good indicator to find patients.

Comparative Study of Organizational Measures on Helmet Use Rate in Trang Hospital Personnel

2021 ◽  
Vol 104 (2) ◽  
pp. 247-251
Keyword(s):  
Video Camera ◽  
P Value ◽  
Policy Measure ◽  
Chi Square ◽  
Helmet Use ◽  
Before And After ◽  
Chi Square Test ◽  
Policy Measures ◽  
The Mean ◽  
A Prospective Study

Objective: To compare the efficacy of organizational measures on helmet use rate of the motorcycle driver and rider in Trang Hospital. Materials and Methods: The present study was a prospective study comparing the helmet use rate before and after the measures including helmet policy, supportive and incentive organizational measure, and penalizing organizational measure. The personnel of Trang Hospital included 1,441 people. There were 637 drive-only personnel, 143 ride-only personnel and 443 drive-ride personnel. The helmet use rate was collected at the front gate of the hospital by closed circuit video camera monitoring during 07:00 am to 08:30 am every day for one week before and after the various measures. The mean helmet use rates were compared by the chi-square test was considered significant at the p value of less than 0.05. Results: The increased rate of helmet use in driver after the supportive and incentive organizational measure and the penalizing organizational measure compared to the helmet use rate before the policy measures were statistically significant (p<0.001). Unlike the increased rate of helmet use in driver and rider after the policy measure compared to the helmet use rate before the policy measure were not statistically significant (p=0.220, 0.470, consecutively). The increased helmet use of the rider after the penalizing organizational measure was statistically significant when compared to the helmet use rate before the policy (p<0.001), and the supportive and incentive measure (p=0.019). However, the increased rate of helmet use in driver after the penalizing organizational measure compared to the helmet use rate after the supportive and incentive organizational measure were not statistically significant (p=0.990). Conclusion: Only the policy measure has not significantly increased the rate of helmet use in both drivers and riders. The supportive and incentive organizational measure have significantly increased the helmet use rate in the drivers, but not significantly increased the rate of helmet use in the riders. However, the penalizing organizational measure has significantly increased the rate of helmet use in the riders, but not significantly increased the rate of helmet use in the drivers. Keywords: Helmet implementation, Organizational measure, Head injury prevention, Motorcycle accident, Helmet use rate

scholarly journals EFFICACY OF THROMBOLYSIS (STREPTOKINASE) IN DIABETIC AND NON-DIABETIC PATIENTS PRESENTING WITH ACUTE ST ELEVATION MI & COMPARISON OF THEIR ANGIOGRAPHIC PROFILE.

2021 ◽  
pp. 1-5
Author(s):  
Ashish Chauhan ◽  
Rajeev Kumar Gupta ◽  
V.V. Agarwal
Keyword(s):  
Fibrinolytic Therapy ◽  
P Value ◽  
Diabetic Patients ◽  
Chi Square ◽  
Acute Stemi ◽  
Atypical Symptoms ◽  
Triple Vessel Disease ◽  
Qualitative Variables ◽  
Chi Square Test ◽  
St Elevation

BACKGROUND: To determine the efficacy of streptokinase in diabetic versus non-diabetic patients presenting with acute ST Elevation Myocardial Infarction (STEMI). METHOD AND RESULTS: This is a hospital based observational study conducted in the department of Cardiology, S.M.S. MEDICAL COLLEGE and associated hospital, Jaipur, Rajasthan between March 2016 to August 2017. Two hundred one consecutive patients of acute STEMI admitted to the Cardiology department were enrolled in the study to maintain 95% CI and 80% power of study. Patients with acute STEMI within 12 hours of chest pain without contraindications to fibrinolytic therapy (streptokinase) were included. ECG was done before and at 90 minutes after the start of streptokinase. ST-segment resolution equal to or more than 70% at 90 minutes on ECG was taken as successful reperfusion. The data was analysed by using software SPSS version 10. The quantitative variables were presented as mean and standard deviation while qualitative variables as frequency and percentage. Chi square test was used to estimate significance and p-value of <0.05 was considered significant. Out of 201 patients, 127(63.2%) were non-diabetics and 74(36.8%) were diabetics. The age of presentation of these patients was 32-75yr (meanage=55.59yr). Of these patients, 80% (N=160) were male and 20% (N=40) were female. Among the 74 diabetic patients, streptokinase was not effective in any patients. So streptokinase is non-efficacious in diabetic patients. Among the 127 non diabetic patients, streptokinase was effective in 79 (62.2%). Among the risk factors, smoking and hypertension were found in 84.6% and 62.7% of the patients respectively. So, we found smoking as the most common risk factor followed by HTN and DM in our patients. HTN was found significantly more in diabetic patients (94.59%) vs (44.09% in non-diabetic patients). On angiography, 58.7% patients had SVD, 34.8% had DVD and 6.5% had TVD. Five (2.5%) of these were found to have LM disease. Coronary angiography showed SVD, DVD, TVD in 44(59.46%), 17(22.97%) and 13(17.57%) of diabetic vs 74(58.27%), 53(41.73%) and 0(0%) of non-diabetic patients. So, triple vessel disease is significantly higher in diabetic patients. CONCLUSION: This study shows that streptokinase is significantly more efficacious in non-diabetics as compare to diabetic patients presenting with acute STEMI. It is more efficacious in male than female (M=47.82%; F=5%). We found that the window period of presentation was significantly higher in diabetic patient because of atypical symptoms that may lead to a delay in seeking medical advice and streptokinase was significantly more efficacious in non-diabetics as compare to diabetic patients.

scholarly journals Testing The Mean For Business Data: Should One Use The Z-Test, T-Test, F-Test, The Chi-Square Test, Or The P-Value Method?

2006 ◽  
Vol 3 (7) ◽  
Author(s):  
Jiajuan Liang ◽  
William S. Pan
Keyword(s):  
Categorical Data ◽  
T Test ◽  
P Value ◽  
F Test ◽  
Chi Square ◽  
P Values ◽  
Chi Square Test ◽  
The Mean ◽  
The Relationship ◽  
Two Populations

In testing the mean of a population or comparing the means from two populations. There are several statistics available: the t-test, z-test, F-test and the chi-square test. Both the t-test and the z-test are usually used for continuous populations, and the chi-square test is used for categorical data. The F-test is used for comparing more than two means. In this paper we will discuss: 1) the conditions on using these tests; 2) the relationship among these test; and 3) illustration of the p-values of these tests by graphs. Some concluding remarks will be provided.

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