Compositional Analyses and Cytotoxic Activity of Star Anise (Illicium Verum) Essential Oils in Vietnam

By means of the gas chromatography-mass spectrometry (GC/MS) method, 21 volatile components have been identified in the essential oils of fruits and the leaves of star anise (Illicium verum Hook. f., Illiciaceae) in Vietnam, in which, essential oil of star anise fruits has 18 components, essential oil of star anise leaves has 16 components, with content have been determined more than 98.60% total compounds of essential oil. The major compound was identified as trans- anethole with 87.05% in leaves essential oil and 90.12% in fruits essential oil. The in vitro anti-cancer activity of star anise essential oil was evaluated by cytotoxicity assay. The results showed that the essential oil obtained from leaves of star anise inhibited the grow of liver cancer cell (IC50 = 10.22 µg/ml) and colon cancer cell (IC50 = 6.26 µg/ml). The essential oil obtained from fruits of star anise inhibited the grow of liver cancer cell and colon cancer cell with the IC50 values of 5.93 and 3.20 µg/ml, respectively.

Download Full-text

In Vitro Cytotoxicity and Apoptotic Assay of Eucalyptus globulus Essential Oil in Colon and Liver Cancer Cell Lines

Journal of Gastrointestinal Cancer ◽

10.1007/s12029-021-00601-5 ◽

2021 ◽

Author(s):

Hajar Khazraei ◽

Seyedeh Azra Shamsdin ◽

Mozhdeh Zamani

Keyword(s):

Liver Cancer ◽

Essential Oil ◽

Cell Lines ◽

Cancer Cell ◽

Eucalyptus Globulus ◽

Cancer Cell Lines ◽

In Vitro Cytotoxicity ◽

Liver Cancer Cell

Download Full-text

Essential oil of Origanum majorana L., Illicium verum Hook. f. and Cinnamomum zeylanicum Blume: chemical and antimicrobial characterization

Revista Brasileira de Plantas Medicinais ◽

10.1590/s1516-05722011000200013 ◽

2011 ◽

Vol 13 (2) ◽

pp. 209-214 ◽

Cited By ~ 9

Author(s):

J.M Freire ◽

M.G Cardoso ◽

L.R Batista ◽

M.A Andrade

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Minimal Inhibitory Concentration ◽

Inhibitory Concentration ◽

Inhibitory Effect ◽

Cinnamomum Zeylanicum ◽

E Coli ◽

Star Anise ◽

Illicium Verum ◽

Origanum Majorana

Essential oils of Origanum majorana L. (marjoram), Illicium verum Hook. f. (star-anise) and Cinnamomum zeylanicum Blume (cinnamon) were obtained by steam distillation using a modified Clevenger device. The antimicrobial activity of each oil was evaluated against the bacteria Staphylococcus aureus, Escherichia coli and the fungi Aspergillus flavus and Aspergillus parasiticus by observing their growth and/or mycelial inhibition through comparison with the standard dish (without oil). The essential oils were analyzed using a gas chromatograph coupled to a mass spectrometer for identification and coupled to a flame ionization detector for quantification. The major constituents of marjoram, star-anise and cinnamon essential oils were 4-terpineol, trans-anetole and cinnamic aldehyde, respectively. In in vitro tests, essential oils of marjoram and cinnamon promoted an inhibitory effect on the bacteria S. aureus and E. coli, while the essential oil of star-anise presented activity only against E. coli. Marjoram, star-anise and cinnamon oils were effective against the studied fungi, presenting an inhibitory effect. The minimal inhibitory concentration for the mycelial growth of A. parasiticus was 1 and 0.01 µL mL-1 for star-anise and cinnamon oils, respectively. The minimal inhibitory concentration for A. parasiticus was 0.25, 2 and 2 µL mL-1 for cinnamon, star-anise and marjoram oils, respectively.

Download Full-text