scholarly journals Giving up on everything: a case and review of pervasive refusal syndrome

2020 ◽  
pp. 57-59
Author(s):  
Jordan Ho ◽  
Brynn Charron
Keyword(s):  
Female Patient ◽  
Self Care ◽  
Therapeutic Options ◽  
Clinical Knowledge ◽  
Current State ◽  
Pervasive Refusal Syndrome

We present a case of pervasive refusal syndrome (PRS), in which a 11-year-old female patient refused to eat, drink, interact, or self-care in any way.  The patient was kept on IV nutrition and multiple therapeutic options were tried to no effect. After 18 months, the patient spontaneously recovered with no lasting harm, and her symptoms did not recur.  We further discuss the current state of clinical knowledge on PRS, as well as the form that has appeared amongst children in asylum-seeking families in Sweden.

scholarly journals Pervasive refusal syndrome

2004 ◽  
Vol 10 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Bryan Lask
Keyword(s):  
Age Groups ◽  
Self Care ◽  
Well Being ◽  
Treatment Needs ◽  
Resistance To Treatment ◽  
Younger Age ◽  
Pervasive Refusal Syndrome ◽  
Life Threatening

Pervasive refusal syndrome is a severe, pervasive and life-threatening disorder. Most commonly seen in girls between the ages of 8 and 15, although also affecting boys and younger age groups, it is characterised by a profound and pervasive refusal to eat, drink, talk, walk and engage in any form of self-care. A determined resistance to treatment is a striking component of the condition. The causes are unclear, but likely to be complex, multiple and associated with a sense of hopelessness. Treatment needs to be comprehensive and is based on supporting the child in recovering at her own pace, while ensuring physical safety and well-being. The prognosis is good, provided treatment is appropriate, but recovery tends to take a year or more.

scholarly journals Understanding and Targeting the Wnt/β-Catenin Signaling Pathway in Chronic Leukemia

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
S. Thanendrarajan ◽  
Y. Kim ◽  
I. G. H. Schmidt-Wolf
Keyword(s):  
B Cell ◽  
Signaling Pathway ◽  
Solid Tumors ◽  
Wnt Pathway ◽  
Hematological Malignancies ◽  
Therapeutic Options ◽  
Special Focus ◽  
Chronic Leukemia ◽  
Current State ◽  
Experimental Approaches

It has been revealed that the Wnt/β-catenin signaling pathway plays an important role in the development of solid tumors and hematological malignancies, particularly in B-cell neoplasia and leukemia. In the last decade there have been made experimental approaches targeting the Wnt pathway in chronic leukemia. In this paper we provide an overview about the current state of knowledge regarding the Wnt/β-catenin signaling pathway in chronic leukemia with special focus on therapeutic options and strategies.

Self-Administration of Medication in Hospital: A Literature Review

2020 ◽  
Vol 33 (3) ◽  
pp. 249-257
Author(s):  
Toke Vanwesemael ◽  
Koen Boussery ◽  
Tinne Dilles
Keyword(s):  
Literature Review ◽  
Self Care ◽  
Research Practice ◽  
Self Administration ◽  
Current State ◽  
Growing Body ◽  
Definition Of Health ◽  
Definition Of ◽  
Care Deficit ◽  
Deficit Theory

The idea of patients self-administering their medication in hospital is not new; it was first cited in literature in 1959. Up to date, there is a growing body of literature that recognizes the importance of this approach. In this current state of the literature, self-administration of medication in hospital is positioned in the context of the definition of health as proposed by Huber et al. and Orem’s self-care deficit theory: first identify the concept of medication self-administration, as well as the prevalence, existing procedures, tools, and proven effects of interventions; then the findings should point the way forward for research, practice, and policy.

M423 INVESTIGATION OF THE CURRENT STATE REGARDING JAPANESE WOMEN WITH URINARY INCONTINENCE SYMPTOMS AND SELF-CARE ACTIVITY

2012 ◽  
Vol 119 ◽  
pp. S667-S667
Author(s):  
K. Masaki ◽  
S. Ninomiya ◽  
A. Sakamoto ◽  
Y. Endo ◽  
S. Morikawa ◽  
...  
Keyword(s):  
Urinary Incontinence ◽  
Self Care ◽  
Japanese Women ◽  
Current State ◽  
Care Activity

scholarly journals Large granular lymphocytic leukemia: molecular pathogenesis, clinical manifestations, and treatment

Hematology ◽  
2012 ◽  
Vol 2012 (1) ◽  
pp. 652-659 ◽  
Author(s):  
Dan Zhang ◽  
Thomas P. Loughran
Keyword(s):  
Clinical Manifestations ◽  
Lymphocytic Leukemia ◽  
Therapeutic Options ◽  
Term Survival ◽  
Therapeutic Modalities ◽  
Activation Induced Cell Death ◽  
Chronic Antigenic Stimulation ◽  
Current State ◽  
Prospective Trials ◽  
Lgl Leukemia

Abstract Large granular lymphocyte (LGL) leukemia represents a spectrum of rare lymphoproliferative diseases defined by clonal amplification of either CD3+ cytotoxic T-lymphocytes or CD3− natural killer cells. This chapter focuses on the T-cell form of LGL leukemia. Clinical features include neutropenia, anemia, and rheumatoid arthritis. LGL leukemia is thought to arise from chronic antigenic stimulation, with the long-term survival of LGL being promoted by constitutive activation of multiple survival signaling pathways, such as the JAK/STAT3, sphingolipid, and Ras/MEK/ERK pathways. Therefore, these lead to global deregulation of apoptosis and resistance to normal pathways of activation-induced cell death. The majority of LGL leukemia patients eventually need treatment. Treatment of leukemic LGL is based on immunosuppressive therapy, primarily using low doses of methotrexate or cyclophosphamide. However, no standard therapy has been established because of the lack of large, prospective trials. In addition, because some patients are refractory to currently available treatments and none of these therapeutic modalities can cure LGL leukemia, new therapeutic options are needed. Understanding the current state of the pathogenesis of LGL leukemia may provide insights into novel therapeutic options.

Fatal Bleeding Due to a Heparin-Like Anticoagulant in a 37-Year-Old Woman Suffering From Systemic Mastocytosis

2008 ◽  
Vol 14 (3) ◽  
pp. 360-364 ◽  
Author(s):  
Christoph Sucker ◽  
Georg Mansmann ◽  
Stefan Steiner ◽  
Norbert Gattermann ◽  
Anette Schmitt-Graeff ◽  
...  
Keyword(s):  
Female Patient ◽  
Clinical Presentation ◽  
Systemic Mastocytosis ◽  
Therapeutic Options ◽  
Refractory Disease ◽  
Fatal Bleeding ◽  
Laboratory Procedures

A 37-year-old female patient with systemic mastocytosis who was admitted with severe unexplained bleeding symptoms is studied. Laboratory procedures established the diagnosis of a patient-derived—heparin-like anticoagulant as a very rare hemostatic abnormality predisposing to bleeding. The patient died from refractory disease despite therapy with protamine, initiation of chemotherapy, and supportive measures. The case illustrates the clinical presentation and diagnosis of heparin-like anticoagulants. Etiology, pathophysiology, and therapeutic options are discussed.

scholarly journals Headache Attributed to Temporomandibular Disorders. Case Report

2020 ◽  
pp. 121-130
Author(s):  
Andrés Cervantes Chavarría ◽  
Adriana Espinoza Chacón
Keyword(s):  
Case Report ◽  
Physical Therapy ◽  
Temporomandibular Joint ◽  
Diagnostic Criteria ◽  
Female Patient ◽  
Temporomandibular Disorders ◽  
Clinical Case ◽  
Myofascial Pain ◽  
Self Care ◽  
Diagnostic Process

The goal of this article was to review the most common temporomandibular disorders according to the Diagnostic Criteria for Temporomandibular disorders (DC/TMD) emphasizing in the criteria for headache attributed to TMD. By presenting a clinical case that shows the characteristics of a patient with masticatory myofascial pain, arthralgia of the temporomandibular joint and headache attributed to TMD. A case of a 34-year-old female patient is presented, the diagnostic process and its approach: self-care, modification of parafunctional habits and behaviors, physical therapy and pharmacological support.

scholarly journals Hernia gástrica atascada en ventana pericardio-peritoneal. Una rara complicación

2020 ◽  
Vol 112 (2) ◽  
pp. 193-196
Author(s):  
José A Acevedo ◽  
◽  
Julio G. Caballero ◽  
Alejandra Lencinas ◽  
Martín Córdoba ◽  
...  
Keyword(s):  
Pericardial Effusion ◽  
Female Patient ◽  
Aspiration Pneumonia ◽  
Clinical Presentation ◽  
Therapeutic Options ◽  
Peritoneal Window

We report the case of a 73-year- old female patient with vomiting, aspiration pneumonia and constitutional symptoms. The imaging tests showed total gastric herniation in the pericardial sac through a pericardio-peritoneal window previously created. The case was solved with surgery. The therapeutic options for persistent pericardial effusion are considered. Intrapericardial gastric hernia as a complication, its clinical presentation, intraoperative findings, complementary tests and treatment are discussed.

Sign in / Sign up

Export Citation Format

Share Document