Phytochemical and Pharmacological Properties of Catharanthus roseus (Vinca)

2021 ◽  
Vol 1 (4) ◽  
pp. 429-434
Author(s):  
Gautam Kumar ◽  
Ravi Kumar ◽  
Girendra Kumar Gautam ◽  
Harshit Rana

Vinca alkaloids obtained from Madagascar are a subset of drugs. Generally, they are naturally extracted from the Vinca rosea plant, Catharanthus roseus G, Don and show hyperglycemia activity as well as cytotoxic effects. It is used to treat various diseases such as diabetes, hypertension, cancer, asthma, inflammation, malaria, angiogenesis, brain imbalance, dysentery, and is also used as a disinfectant that occurs due to potent microorganisms. The vinca alkaloids are played an essential role to fight cancer disease. There are some major vinca alkaloids in clinical use: Vinblastin, Vincristine, Vindesine, tabersonine, vinorelbine, and Vinpocetine, etc. The flowers juice of Vinca rosea is utilized to treat several skin problems e.g. acne, eczema, and dermatitis. According to our opinion that it may be help scientists, ayurvedic practitioners, pharmacognosists, botanists, researchers, and students who are active in the field of medicinal plants research.

Author(s):  
Harish Rajak ◽  
Murli Dhar Kharya ◽  
Pradeep Mishra

There are vast numbers of pharmacologically active heterocyclic compounds in regular clinical use. The presence of heterocyclic structures in diverse types of compounds is strongly indicative of the profound effects such structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic drugs. The 1,3,4-oxadiazole nucleus has emerged as one of the potential pharmacophore responsible for diverse pharmacological properties. Medical Literature is flooded with reports of a variety of biological activities of 2,5-Disubstituted-1,3,4-oxadiazoles. The present work is an attempt to summarize and enlist the various reports published on biologically active 2,5-disubstituted-1,3,4-oxadiazoles.


Author(s):  
Fatemeh Hosseinpour-Jaghdani ◽  
Tahoora Shomali ◽  
Sajedeh Gholipour-Shahraki ◽  
Mohammad Rahimi-Madiseh ◽  
Mahmoud Rafieian-Kopaei

AbstractMedicinal plants that are used today have been known by people of ancient cultures around the world and have largely been considered due to their medicinal properties.


Author(s):  
Владимир Александрович Бабиков ◽  
Кристина Алексеевна Тимофеева

В представленной статье рассматриваются особенности экологии лекарственных растений, произрастающих на территории Бичурского района Бурятии, и их применение в традиционной тибетской медицине. На основе собранных сведений назрела необходимость подробного изучения фармакологических свойств изучаемых растений, с учетом мер по охране и сохранению их в флоре Бичурского района. The article deals with the peculiarities of the ecology of medicinal plants growing on the territory of the Bichursky district of Buryatia, and their application in traditional Tibetan medicine. Based on the collected information, there is a need for a detailed study of the pharmacological properties of the studied plants, taking into account measures for the protection and preservation of them in the flora of the Bichursky district.


2011 ◽  
Vol 6 (12) ◽  
pp. 1934578X1100601 ◽  
Author(s):  
Maria del Rosario Jacobo-Salcedo ◽  
Angel Josabad Alonso-Castro ◽  
Luis A. Salazar-Olivo ◽  
Candy Carranza-Alvarez ◽  
Luis Ángel González-Espíndola ◽  
...  

The antimicrobial effects of the Mexican medicinal plants Guazuma ulmifolia, Justicia spicigera, Opuntia joconostle, O. leucotricha, Parkinsonia aculeata, Phoradendron longifolium, P. serotinum, Psittacanthus calyculatus, Tecoma stans and Teucrium cubense were tested against several human multi-drug resistant pathogens, including three Gram (+) and five Gram (-) bacterial species and three fungal species using the disk-diffusion assay. The cytotoxicity of plant extracts on human cancer cell lines and human normal non-cancerous cells was also evaluated using the MTT assay. Phoradendron longifolium, Teucrium cubense, Opuntia joconostle, Tecoma stans and Guazuma ulmifolia showed potent antimicrobial effects against at least one multidrug-resistant microorganism (inhibition zone > 15 mm). Only Justicia spicigera and Phoradendron serotinum extracts exerted active cytotoxic effects on human breast cancer cells (IC50≤30 μg/mL). The results showed that Guazuma ulmifolia produced potent antimicrobial effects against Candida albicans and Acinetobacter lwoffii, whereas Justicia spicigera and Phoradendron serotinum exerted the highest toxic effects on MCF-7 and HeLa, respectively, which are human cancer cell lines. These three plant species may be important sources of antimicrobial and cytotoxic agents.


Author(s):  
Isha Kumari ◽  
Gitika Chaudhary

Nature has gifted humans a vast variety of medicinal plants, which are the rich source of bioactive compounds. Calotropis procera is an important medicinal plant that belongs to the family asclepiadaceae. It is commonly known as madar and milkweed plant in english and arka in hindi. It is mostly found in the tropics of asia and africa. Calotropis procera is a highly valued plant in the folk medication system. Each part of the plant is richly endowed with diverse nature of phytochemical constituents like alkaloids, proteins, vitamins, carbohydrates, saponins, terpenes, and flavonoids, etc. These phytochemicals are significantly associated with various therapeutic and pharmacological properties such as anti-microbial, anti-oxidant, anti-inflammatory, anti-ulcer, antifertility, anti-diarrheal, and spasmolytic. In this review article, the therapeutic and pharmacological value of this important plant has been summarized along with its utilization in the folklore and ayurvedic medicinal system.


2022 ◽  
pp. 179-194
Author(s):  
Sandeep Kumar ◽  
Ahmad Hussain ◽  
Manish Singh Sansi ◽  
Daraksha Iram ◽  
Priyanka ◽  
...  

The medicinal plants have been used by humans since ancient times, and the great civilizations of the world in ancient times were well aware of the benefits brought by the use of medicinal plants. This chapter provides important information regarding medicinal plants that have a wide variety of antioxidative agents ranging from bitter compounds that stimulate digestion system, phenolic compounds for antioxidant and numerous other pharmacological properties, antibacterial, and antifungal to tannins that act as natural antibiotics, diuretic substances, alkaloids, and so forth.


2001 ◽  
Vol 1 (2) ◽  
pp. 74-77
Author(s):  
Sahito S. R. ◽  
T.G. Kazi ◽  
G. H. Kazi ◽  
M. A. Jakhrani ◽  
M .S. Shaikh

2020 ◽  
Vol 147 ◽  
pp. 112198 ◽  
Author(s):  
Abdelhakim Bouyahya ◽  
Omar Belmehdi ◽  
Abdelaziz Benjouad ◽  
Rabii Ameziane El Hassani ◽  
Saaïd Amzazi ◽  
...  

CYTOLOGIA ◽  
2018 ◽  
Vol 83 (3) ◽  
pp. 277-282 ◽  
Author(s):  
Sazada Siddiqui ◽  
Saad Alamri ◽  
Suleiman Al-Rumman ◽  
Mahmood Moustafa

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