scholarly journals Drug utilization pattern and rational drug use at orthopedics and traumatology outpatient clinics: A cross-sectional study

2021 ◽  
Vol 32 (3) ◽  
pp. 759-766
Author(s):  
İhsan Özdamar ◽  
Emine Nur Özdamar
Author(s):  
Sonal M. Parekar ◽  
Girish K. Maindarkar ◽  
Vishal V. Maindarkar

Background: Drug utilization study is essential, as safe and effective therapeutic regimen in paediatric population is challenging. Pattern of use of drugs in pediatrics vary as compared to adults, also there is limited data available. The objective of this study was to study drug utilization pattern in pediatric patients attending pediatric outpatient department of Maindarkar pediatric hospital, Latur.Methods: A cross sectional study was carried out for a period of six months from September 2019 to February 2020, by analysing a total 1000 prescriptions of patients who had visited the OPD of Maindarkar pediatric hospital. Prescriptions were selected by simple random sampling method.Results: In our study, out of the total of 1000 prescriptions, 244 (24.4%) were of neonates, 556 (55.6%) were of infants (1 month to 1 year) and 200 (20%) were of children above 1 year. 547 (54.7%) prescriptions were of male patients and 453 (45.3%) were of female patients. The most frequent classes of drugs prescribed were nonsteroidal anti-inflammatory drugs 704 (70.4%), followed by drugs used for respiratory disorders 655 (65.5%) and supplements (60%). Antimicrobials were prescribed in 498 (49.8%) prescriptions. The average number of drugs per prescription was 2.45. About two third of all the prescribed drugs (74.41%) were from national essential medicine list. Most of the prescriptions had oral drug formulation 825 (82.5%) followed by inhalational 208 (20.8%) followed by injectables 150 (15%). All the drugs were prescribed by brand names.Conclusions: Our study helps health-care system to understand, interpret and improve prescribing, administration, to minimize adverse events and promote rational use of medicines.


Author(s):  
Siddharth Pravin Agrawal ◽  
Suhani V. Patel ◽  
Supriya Malhotra ◽  
Pankaj R. Patel

Background: Osteoporosis (OP) is a silently progressing metabolic bone disease that results in loss of mineralized bone and subsequent fractures with minor trauma. Fracture related pain and physical inability to perform activities of daily living can lead to psychological consequences that impair Quality of Life (QoF). However, much less is known about Indian scenario. Hence, our study becomes imperative. Aim of this study to the drug utilization pattern and to analyze Quality of life of postmenopausal women suffering from osteoporosis.Methods: An analytical cross-sectional study was done on 91 post-menopausal osteoporotic women. Drug utilization pattern was evaluated. Pre-validated QUALEFFO-31 questionnaire was administered to each patient to record patient’s perceived QoL. Scores were calculated according to the algorithm. Higher scores indicated poor QoL. The collected data was analyzed with SPSS software (version 23)and p value ≤0.05 was considered as statistically significant.Results: The mean age group of presenting patients was 56.2±6.6 years. All the patients received Calcium and vitamin D supplements and non-steroidal anti-inflammatory drugs for pain relief. But only 33% of the patients received any one of the bisphosphonates (BP). For analysis, patients were grouped into Group-1(n=60) who did not and Group-2 (n=31) who did receive a BP. QOL analysis showed that pain domain was affected the most. Also, patients in Group 2 reported worse score in all the domains in comparison to Group 1 (P<0.05). It is likely that BP might need more time to show considerable effect or because it was added only to those patients who already had more complaints and could afford the high cost.Conclusion: BP in spite of being the drug of choice for OP is used less commonly in India. OP causes pain and physical debilitation with detrimental effect on mental health. Longer duration prospective studies are needed to study the association of QoL and use of BP in OP patients.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Niguse Meles Alema ◽  
Getachew Semagn ◽  
Shetey Melesse ◽  
Ephrem Mebrahtu Araya ◽  
Hagazi Gebremedhin ◽  
...  

Abstract Background A vigilant prescription of drugs during pregnancy can potentially safeguard the growing fetus from the deleterious effect of the drug while attempting to manage the mother’s health problems. There is a paucity of information about the drug utilization pattern in the area of investigation. Hence, this study was implemented to investigate the pattern of drug utilization and its associated factors among pregnant women in Adigrat general hospital, Northern Ethiopia. Methods An institution-based cross-sectional study was conducted among randomly selected 314 pregnant women who attended obstetrics-gynecology and antenatal care units of the hospital. Relevant data were retrieved from the pregnant women’s medical records and registration logbook. The drugs prescribed were categorized based on the United States Food and Drug Administration (US-FDA) fetal harm classification system. Data analysis was done using SPSS version 20 statistical software. Multivariate logistic regression was employed to analyze the association of the explanatory variables with the medication use, and p < 0.05 was declared statistically significant. Results The overall prescribed drug use in this study was found to be 87.7%. A considerable percentage of the study participants (41.4%) were prescribed with supplemental drugs (iron folate being the most prescribed drug) followed by antibiotics (23.4%) and analgesics (9.2%). According to the US-FDA drug’s risk classification, 42.5, 37, 13, and 7% of the drugs prescribed were from categories A, B, C, and D or X respectively. Prescribed drug use was more likely among pregnant women who completed primary [AOR = 5.34, 95% CI (1.53–18.6)] and secondary education [AOR = 4.1, 95% CI (1.16–14)], who had a history of chronic illness [AOR = 7.9, 95% CI (3.14–19.94)] and among multigravida women [AOR = 2.9, 95% CI (1.57 5.45)]. Conclusions The finding of this study revealed that a substantial proportion of pregnant women received drugs with potential harm to the mother and fetus. Reasonably, notifying health practitioners to rely on up-to-date treatment guidelines strictly is highly demanded. Moreover, counseling and educating pregnant women on the safe and appropriate use of medications during pregnancy are crucial to mitigate the burden that the mother and the growing fetus could face.


2021 ◽  
pp. 20-23
Author(s):  
Giridhar Dasegowda ◽  
Girish M Bengalorkar ◽  
Salma Sadaf ◽  
Priyanka Prasanna Kumar Belaguthi ◽  
Sanjiti Mirmire ◽  
...  

Background: Stroke is not only one of the leading causes of morbidity and mortality worldwide but is also a topic of major public health concern in developing countries with a prevalence of 44 - 559 per 100,000 people. This study focuses on risk factors, socioeconomic distribution, drug utilization pattern, rehabilitation of patients and possible solutions to the encountered problems. Methods: Patients admitted to ESIC MC & PGIMSR, Bangalore were included in this cross-sectional study. A complete prole of patients diagnosed with stroke was obtained. On analysing the data obtained from 51 patients Results: under study, it was noted that ischemic stroke was the highest (84.31%), and stroke in males (70.59%) was higher than among females (29.41%) with highest occurrences between 55-70 years of age (41.18%). A large number of people were found to have >=3 risk factors (72.54%), including hypertension (78.43%), alcoholism (50.98%), diabetes mellitus (49.02%), smoking (47.05%), and dyslipidemia (27.45%). It was found that an average patient is prescribed 3.01 drugs in generic name and 4.68 in brand name (p<0.05). The study also highlighted the inadequacy of physiotherapy (39.21%), speech-therapy (11.76%) and occupational-therapy (0%). An understanding of risk factors and drug prescription strategies fol Conclusion: lowed by physicians across different socioeconomic groups helps to ne tune management strategies in accordance with guidelines, to provide a better quality of life to patients.


Author(s):  
Angel Maria Augustine ◽  
Dessai Sneha Shamrao ◽  
Sujan Basnet ◽  
Anchan Namita Bhoja ◽  
Javedh Shareef

Objective: This study was carried out to assess the drug utilization pattern of calcium, Vitamin D supplements, and anti-osteoporosis drugs in patients with osteoporotic fracture in an Indian teaching hospital.Methods: A cross-sectional study was carried out for 6 months in outpatients receiving treatment from the orthopedic department of an Indian teaching hospital. Demographic details, comorbidities, types of fracture, laboratory parameters, and drug therapy were collected from the patient case records who met the study criteria and documented in the data collection form. All the collected details were later analyzed using descriptive statistics.Results: A total of 73 patient’s prescriptions were reviewed, in which 45.2% were male and 54.8% were female. Majority of the patients were in the age group of 50–60 years with mean age of 63.52±11.06 years. Hypertension (27.16%) was the highest comorbidity identified in the study followed by diabetes (18.51%) and coronary artery disease (14.81%). Of the total patients, 65.75% were prescribed with calcium and Vitamin D supplements and 2.73% received bisphosphonates.Conclusion: The study shows the pattern of drug use in elderly with osteoporotic fractures. Since calcium and Vitamin D are vital for treating osteoporotic fractures, adequate monitoring of serum levels of calcium and Vitamin D3 may help to prescribe doses with desired need and safety level.


2005 ◽  
Vol 39 (3) ◽  
pp. 527-532 ◽  
Author(s):  
Claudia Vacca ◽  
José Orozco ◽  
Albert Figueras ◽  
Dolors Capellà

BACKGROUND: Appropriate dispensing is one of the steps for rational drug use, so it is generally advised that the dispenser should have relevant and updated knowledge, skills, and attitudes. OBJECTIVE: To assess pharmacies and nonprofessional employees' (NEs) skills and knowledge, as well as their response to several specific case simulations in Bogotá, Colombia. METHODS: A descriptive cross-sectional study was performed on a random sample of 371 pharmacies in Bogotá. Information from each pharmacy was obtained using 2 approaches: (1) direct interview to collect data on organizational aspects of the store and characteristics of NEs, and (2) simulation (both by direct interview and by telephone) to assess dispensing responses in 6 simulated clinical cases. RESULTS: More than half of the simulated clinical situations resulted in inappropriate dispensing (direct simulations 57%; telephone simulations 55%). The proportion of correct answers to theoretical questions regarding a specific therapeutic problem during interviews was higher than the response when a simulation presented that same case and a dispensing act was expected. The educational background of the NEs included in the study points to a specific problem: two-thirds of the individuals selling medicines had completed only secondary-level education and only 2% of the sample had a pharmacist as technical director. Continuing education courses were either directly organized by drug manufacturers (one-third of the courses attended by pharmacists) or sponsored by them (more than an additional one-third). CONCLUSIONS: NEs should be considered part of the therapeutic chain and, if appropriately updated or instructed, could play a very important role in the always difficult promotion of rational drug use. Public health institutions and universities should be more actively involved in the provision of independent, unbiased, and essential information on common therapeutic problems, safety concerns, and new drug prescription restrictions.


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