scholarly journals A rare cause of osteomyelitis of distal phalanx: Candida lusitaniae

2021 ◽  
Vol 32 (2) ◽  
pp. 556-559
Author(s):  
Erdinc Acar ◽  
Ugur Bezirgan
Keyword(s):  
Candida Species ◽  
Specific Treatment ◽  
Middle Finger ◽  
Definitive Diagnosis ◽  
Distal Phalanx ◽  
Left Hand ◽  
The Third ◽  
First Case ◽  
Candida Lusitaniae

Osteomyelitis of the phalanx caused by Candida species are rare. A 49-year-old female patient was admitted to an external center with a splinter injury of the third phalanx of the middle finger of her left hand about 45 days ago. She was referred to our clinic with persistent pain and discharge, despite four-week antibiotherapy. Debridement and curettage were performed and partial excision of the distal phalanx at an appropriate level was done. Her complaints gradually resolved postoperatively with prescribed antibiotics for the pathogen identified as Candida lusitaniae based on the intraoperative cultures. At her three-month follow-up visit, treatment yielded near-excellent results. To the best of our knowledge, this is the first case of osteomyelitis of the distal phalanx caused by Candida lusitaniae in the literature, highlighting the importance of definitive diagnosis and pathogen-specific treatment, rather than empirical treatment, to achieve favorable results with cure.

scholarly journals Bilateral Multiple Metacarpal Head Avascular Necrosis: A Case Report

2016 ◽  
Vol 101 (9-10) ◽  
pp. 473-477 ◽  
Author(s):  
Wengang Li ◽  
Biao Liu ◽  
Jun Song ◽  
Yan Liu ◽  
Haoyu Liu ◽  
...  
Keyword(s):  
Avascular Necrosis ◽  
Middle Finger ◽  
Left Hand ◽  
The Third ◽  
Metacarpal Head ◽  
Right Hand ◽  
Satisfactory Clinical Result ◽  
Slight Limitation ◽  
The Right

Avascular necrosis of the metacarpal head is a rare disease. We herein report a case with varying degrees of lesions in the third and fourth metacarpal heads of the right hand and the third metacarpal head of the left hand. The patient was a 37-year-old male right-handed mechanical worker who presented with persistent dull pain in the right hand after labor work for more than a year. The 3 lesions in this patient were treated differently based on their clinical imaging manifestations. The neurologic function of the right hand recovered by the 18-month follow-up; only a slight limitation remained in the right middle finger. This is the first report of 1 patent who received 2 different treatment methods simultaneously and both provided a satisfactory clinical result.

Penile Lymphoepithelioma-Like Carcinoma: A Rare Case With PD-L1 Expression

2021 ◽  
pp. 106689692098834
Author(s):  
Raquel Machado-Neves ◽  
Bernardo Teixeira ◽  
Elsa Fonseca ◽  
Pedro Valente ◽  
Joaquim Lindoro ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Tumor Cells ◽  
Rare Case ◽  
Malignant Tumors ◽  
Squamous Cell Carcinomas ◽  
The Third ◽  
The Past ◽  
First Case ◽  
Lymphoplasmacytic Infiltrate

Most malignant tumors of the penis are squamous cell carcinomas (SCC), being divided in 2 groups, one human papillomavirus (HPV)-related and another non-HPV-related, with lymphoepithelioma-like carcinoma (LELC) being one of the rarest HPV-related SCC. In this article, we report a case of a 50-year-old man who presented testicular swelling and pain for the past 3 months. A penile mass was identified, and the patient was submitted to a total penectomy. The penectomy specimen showed an ulcerated lesion at the glans reaching the cavernous bodies. Microscopic examination showed undifferentiated epithelial cells with syncytial growth pattern mix with a dense lymphoplasmacytic infiltrate, consistent with LELC. The tumor cells expressed p16 and all 3 different clones of PDL1 (22C3, SP263, and SP142). The patient is alive and well with a follow-up of 3 months. To our knowledge, this is the third LELC of the penis reported in literature and the first case reported with PDL1 expression.

Low-Grade Mucosa-Associated Lymphoid Tissue Lymphoma Involving the Kidney: Report of 3 Cases and Review of the Literature

2006 ◽  
Vol 130 (1) ◽  
pp. 86-89 ◽  
Author(s):  
Libo Qiu ◽  
Pamela D. Unger ◽  
Robert W. Dillon ◽  
James A. Strauchen
Keyword(s):  
Lymphoid Tissue ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Lymphoid Cells ◽  
Low Grade ◽  
The Third ◽  
First Case ◽  
Abundant Cytoplasm ◽  
History Of

Abstract Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue involving the kidney is rare. We report a series of 3 cases. The first case occurred in an 83-year-old woman who presented with back pain. The second case was a 53-year-old man with a history of sarcoidosis who was found, in the course of evaluation of sarcoidosis, to have a right renal mass. The third case occurred in a 72-year-old man who had a history of periorbital mucosa–associated lymphoid tissue lymphoma and had been treated with surgery and radiation 1 year prior to this presentation. Histologically, all 3 patients showed infiltrate of uniform small-to-medium–sized lymphocytes with irregular nuclear contours and abundant cytoplasm resembling centrocytes or monocytoid lymphoid cells. The first patient received chemotherapy without complications. The second patient underwent a partial nephrectomy and was asymptomatic at the subsequent follow-up. The third patient developed a pulmonary embolism following nephrectomy, and further follow-up is not available.

scholarly journals A Phalangeal Osteoid Osteoma: A Case Report

Pulse ◽  
2016 ◽  
Vol 8 (1) ◽  
pp. 69-72
Author(s):  
Syed Khalequezzaman ◽  
Biva Shrestha Khan ◽  
Bidyut K Saha ◽  
Pankaj Kumar
Keyword(s):  
Osteoid Osteoma ◽  
Complete Resolution ◽  
Surgical Excision ◽  
Middle Finger ◽  
Definitive Diagnosis ◽  
Important Differential Diagnosis ◽  
Local Doctor ◽  
History Of ◽  
Uncommon Condition

Osteoid osteoma is a benign bone forming tumor of the growing skeleton that is most often seen in young men. It represents by pain and radiologic appearance of a nidus surrounded by osteosclerosis that occurs mostly in long bones of the lower extremity. Occurrence of this tumor in the hand is an uncommon condition. A 35 year old right-hand-dominant man presented to our orthopedic and trauma OPD with an approximately 2 year history of right middle finger pain without any history of trauma. He consulted previously with a local doctor and had undergone xray of the hand with no definitive diagnosis. Computed tomography at our institution was consistent with the diagnosis of osteoid osteoma. The patient was treated with surgical excision of the lesion without bone grafting. The diagnosis of osteoid osteoma was confirmed by histopathology. Follow up visit showed complete resolution of pain. In this case demonstrating that osteoid osteoma is an important differential diagnosis in patients with finger pain.Pulse Vol.8 January-December 2015 p.69-72

scholarly journals Symptomatic Medial Bone Excrescence in the Distal Phalanx of the Hallux after the First Metatarsophalangeal Joint Arthrodesis: A Case Report and Radiographic Reviews

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Yuji Maenohara ◽  
Ryutaro Takeda ◽  
Song Ho Chang ◽  
Yasunori Omata ◽  
Sakae Tanaka ◽  
...  
Keyword(s):  
Case Report ◽  
Metatarsophalangeal Joint ◽  
Distal Phalanx ◽  
First Metatarsophalangeal Joint ◽  
First Case ◽  
Significant Difference ◽  
Before And After ◽  
One Year ◽  
Common Manifestation

Medial bone excrescence at the base of the distal phalanx of the hallux is a common manifestation which is rarely painful. In this case report, we described the first case of the excrescence becoming symptomatic one year after a metatarsophalangeal (MTP) joint arthrodesis of the great toe in a 74-year-old female. The medial bony excrescence which was obscure preoperatively became obvious postoperatively in the anteroposterior foot radiographs. The patient was successfully treated by an excision of the excrescence. In order to clarify the pathology of the excrescence, we reviewed the radiographs with respect to the excrescence before and after hallux surgeries including 97 metatarsal osteotomies and 33 MTP joint arthrodesis. The width of the excrescence measured in the anteroposterior foot radiographs displayed substantial increment one month after the hallux surgeries (osteotomy group: 0.9 ± 0.7 vs. 1.5 ± 0.7   mm , p < 0.01 ; arthrodesis group: 1.3 ± 0.8 vs. 1.8 ± 1.0   mm , p < 0.01 ). However, there was no significant difference in the width of the excrescence between one month after surgery and at the most recent follow-up of around 20 months in average after the surgery (osteotomy group: 1.5 ± 0.7 vs. 1.4 ± 0.7   mm , p = 0.62 ; arthrodesis group: 1.8 ± 1.0 vs. 1.8 ± 0.7   mm , p = 0.37 ). The present case and our radiographic review suggested that the postoperative medial bony excrescence was not the result of change of position of the preexisting excrescence. The correction of pronation deformity through hallux surgeries could emphasize the medial bony excrescence and cause symptomatic irritation upon shoe contact.

scholarly journals Case Report: Cardiac Involvement by Lymphoma: Rare but Heterogeneous Condition With Challenging Behaviors

2021 ◽  
Vol 11 ◽  
Author(s):  
Elisa Lucchini ◽  
Marco Merlo ◽  
Mario Ballerini ◽  
Aldostefano Porcari ◽  
Gianfranco Sinagra ◽  
...  
Keyword(s):  
Cardiac Involvement ◽  
Marginal Zone ◽  
Challenging Behaviors ◽  
Marginal Zone Lymphoma ◽  
Unique Case ◽  
The Third ◽  
Cns Prophylaxis ◽  
First Case ◽  
Large B Cell

Cardiac lymphomas are rare extranodal lymphomas involving primarily and secondarily the heart and/or pericardium. Here we describe three cases of cardiac involvement from lymphoma with specific peculiarities: two primary cardiac Diffuse Large B-cell Lymphomas and one secondary involvement from Marginal Zone Lymphoma (MZL). The first case highlights the issue of early CNS relapse and the possible role for CNS prophylaxis; the second case demonstrates the difficulties of interpretation and possible mistakes of different radiologic techniques adopted to evaluate cardiac involvement by lymphoma during follow-up; the third is a unique case of MZL with cardiac involvement. Our aim is to share the findings observed in these cases putting them in relation with data from the literature.

scholarly journals Digital acrometastase as a primary manifestation of a bronchial adenocarcinoma

2018 ◽  
Vol 4 (4) ◽  
pp. 680
Author(s):  
Mounir Rhounimi ◽  
Amine Azirar ◽  
Mohamed Kharmaz ◽  
My Omar Lamrani ◽  
Mohamed Ouadghiri ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Metastases ◽  
Middle Finger ◽  
Distal Phalanx ◽  
Primary Tumors ◽  
Digestive Tube ◽  
Left Hand ◽  
Inflammatory Conditions ◽  
Hands And Feet

<p>Bone metastases of the hands and feet (acrometastases) are rare. Their presentation is variable and is generally confused with certain inflammatory conditions such as rheumatoid arthritis, gout, tenosynovitis, fracture or infection (panartius, osteomyelitis). The etiology of non-digital acrometastases is common to primary tumors with bone metastases (prostate, lung, kidney, breast, thyroid, and digestive tube). However, digital acrometastases are seen almost exclusively during bronchial neoplasia. We describe the case of a 43 year-old man admitted for pain and swelling of the middle finger distal phalanx of the left hand. Etiological assessement was in favor of an unusual secondary localization of bronchial adenocarcinoma. Tumoral causes must always be evoked before any inflammatory digital symptomatology, from where the interest of a good interrogation and a targeted paraclinical assessment. </p>

STUDY OF ADOLESCENT CHILDREN INOCULATED WITH BCG IN EARLY INFANCY

PEDIATRICS ◽  
1950 ◽  
Vol 6 (6) ◽  
pp. 853-861
Author(s):  
MILTON I. LEVINE
Keyword(s):  
Infection Type ◽  
Great Difficulty ◽  
Bcg Vaccine ◽  
Control Group ◽  
Primary Complex ◽  
The Third ◽  
Tuberculin Sensitivity ◽  
First Case ◽  
Subsequent Exposure

This study consists of a follow-up of 1165 adolescent children of whom 601 had been vaccinated with BCG during infancy. The remainder, 564, had been followed from infancy as controls. Approximately 550 of these cases received roentgenographic examinations which were compared with RGs taken during the first 5 years of life. As was to have been expected, roentgenographic evidence of healed lesions of primary pulmonary tuberculosis was found much more frequently in the control group than those in the group vaccinated by BCG. Of the 298 vaccinated cases which received RGs there were three with evidence of a healed pulmonary primary complex. There were also two cases with re-infection tuberculosis of the lungs. Of the 286 controls, there were 27 showing evidence of healed pulmonary primary complex. There were no cases of re-infection tuberculosis in the control group. A study of the three vaccinated cases which developed evidence of a healed primary pulmonary complex suggests that in two of the cases the BCG vaccine was weak or inadequate while in the third case the child has been exposed and was probably vaccinated in the pre-allergic phase of a human tuberculosis infection. Of the two vaccinated cases that developed signs of a re-infection tuberculosis in adolescence, it is evident in the first case that the allergy following a weak BCG inoculation subsided and the child received a subsequent exposure to open tuberculosis, later with the development of the re-infection tuberculosis. The second case with re-infection tuberculosis showed evidence of having lost the tuberculin allergy approximately three years after inoculation. As yet no evidence is forthcoming on the ability of BCG vaccine given in infancy to diminish the tuberculosis mortality rate among adolescents and young adults. There were no tuberculosis deaths in either group. It is evident that the BCG inoculation has the ability to prevent a pulmonary primary tuberculosis, at least during the period of postvaccination tuberculin allergy. There is no evidence to indicate that BCG given in infancy is capable of preventing reinfection tuberculosis in adolescence. It is yet to be demonstrated that if the post-BCG tuberculin allergy is maintained the re-infection type of tuberculosis will be avoided. It would appear from this study that there is great difficulty in determining the efficacy of BCG unless some method of maintaining the potency be devised and a standard accurate means of inoculation be used. It is suggested by this study that the BCG tuberculin sensitivity be maintained by revaccination whenever the skin reaction becomes negative.

Cluster headache in children and adolescents: Ten years of follow-up in three pediatric cases

Cephalalgia ◽  
2011 ◽  
Vol 31 (13) ◽  
pp. 1409-1414 ◽  
Author(s):  
Marco A Arruda ◽  
Lucas Bonamico ◽  
Cleiber Stella ◽  
Carlos A Bordini ◽  
Marcelo E Bigal
Keyword(s):  
Case Report ◽  
Cluster Headache ◽  
Spontaneous Remission ◽  
Response To Therapy ◽  
Case Examples ◽  
The Third ◽  
First Case ◽  
Long Term Follow Up

Background: Cluster headache (CH) is a rare cause of headache in children. Onset before 12 years of age is unusual, and long-term follow-up of pediatric cases has been not reported. Objectives: To report three cases of CH with onset at childhood and at least ten years of follow-up. Methods: Case report. Results: The first case is that of a 12-year-old boy with episodic CH with unilateral pain and striking, bilateral autonomic manifestations, remitted for over eight years. The second case is unique in that it reports a case of chronic CH in a 13-year-old boy with Down syndrome. The third case is that of a 9-year-old girl with episodic CH with remissions of 2 and 5 years. All cases had prominent autonomic features. The frequency and duration of the attacks were similar to those that have been reported in adults. Good response to indomethacin was obtained in two cases, although tolerability issues occurred in one. Conclusion: Sustained, long-term, medical and/or spontaneous remission occurs in CH of early onset. The phenotype and response to therapy in children, at least in these case examples, are similar to equivalent observations in adult patients with CH.

Monoclonal antibody extravasations: Two case reports and literature review

2020 ◽  
pp. 107815522095000
Author(s):  
Alicia Rodríguez-Alarcón ◽  
David Conde-Estévez
Keyword(s):  
Monoclonal Antibody ◽  
Case Report ◽  
Literature Review ◽  
Case Reports ◽  
Rare Complication ◽  
Specific Treatment ◽  
Intravenous Chemotherapy ◽  
Chemotherapy Administration ◽  
First Case

Introduction Extravasation is a rare complication from intravenous chemotherapy administration. Literature about monoclonal antibody (MoAb) extravasations is scarce and also conflicting in how they are classified. Case report We reported two different cases of MoAb extravasations with cetuximab and nivolumab outcome respectively. The administration site appeared inflamed and patients did not report disturbances. Management and outcome: Both extravasations did not require specific treatment. General unspecific measures suffice to properly manage these extravasations and no sequels were observed after long follow-up. Both patients received all further courses of MoAb without any adverse events. Discussion To our knowledge, we reported the first case-report of nivolumab extravasation in the literature. In addition, the cetuximab extravasation management and outcome was in accordance with previously published reports. Both MoAb may be considered as non-aggressive or neutral. We reviewed published information about MoAb extravasations. In conclusion, not all MoAb should be classified in the same category when extravasated and special precautions are warranted with conjugated MoAb and bevacizumab.

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