scholarly journals PENGARUH REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (r-TMS) TERHADAP INTENSITAS NYERI PENDERITA CENTRAL POST-STROKE PAIN (CPSP)

Author(s):  
Dody Perdana Goenadhi ◽  
Jumraini Tammasse ◽  
David Gunawan

  EFFECTS OF REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (r-TMS) TOWARDS PAIN INTENSITY IN PATIENTS WITH CENTRAL POST-STROKE PAIN (CPSP)ABSTRACTIntroduction: About 2,7% patients have experienced central post-stroke pain (CPSP) after stroke attack. Repetitive transcranial magnetic stimulation (r-TMS) is a nonpharmacological method to overcome CPSP.Aims: To determine the effectiveness of r-TMS to reduce pain intensity in patients with CPSP.Methods: Randomized-controlled trial in Wahidin Sudirohusodo hospital and Inggit clinic from December 2017 until May 2018. Subjects were divided to 2 groups; control, who received standard therapy for CPSP, and treatment, who received standard therapy for CPSP and r-TMS. Repetitive transcranial magnetic stimulation was done using 2000 pulse and 10Hz frequency. Pain intensity was measured with Numerical Pain Rating Scale (NPRS) at baseline, after r-TMS until day 10. Data analysis was done by Mann-Whitney test.Results: As much as 30 subjects were divided into 2 groups (15 control and 15 treatment). The difference in NPRS score after 10 days of treatment was statistically higher in the treatment group compared to the control (6,67 vs 4,67, p=0,002).Discussion: There was a significant reduction in pain intensity in the group given r-TMS for 10 cycles.Keywords: Central pain, NPRS, r-TMS, strokeABSTRAKPendahuluan: Sebanyak 2,7% pasien mengalami central post-stroke pain (CPSP) setelah serangan. Efektivitas repetitive transcranial magnetic stimulation (r-TMS) merupakan salah satu metoda nonfarmakologis untuk mengatasi CPSP.Tujun: Mengetahui efektivitas repetitive transcranial magnetic stimulation (r-TMS) terhadap penurunan intensitas nyeri pada penderita CPSP.Metode: Uji klinis terandomisasi di RSUP Dr. Wahidin Sudirohusodo dan Klinik Inggit dari Desember 2017 hingga Mei 2018. Subjek dibagi menjadi 2 kelompok, kelompok kontrol yang mendapat terapi standar dan kelompok perlakuan yang ditambahkan r-TMS. Repetitive transcranial magnetic stimulation dilakukan sebanyak 2000 pulse dengan frekuensi 10Hz. Nyeri diukur dengan Numerical Pain Rating Scale (NPRS) sebelum dan pascaterapi hingga hari ke-10. Analisis data dilakukan dengan uji Mann-Whitney.Hasil: Didapatkan 30 subjek yang dibagi menjadi 2 kelompok (15 kontrol dan 15 perlakuan). Selisih skor NPRS setelah sepuluh hari terapi lebih besar secara signifikan pada kelompok perlakuan dibandingkan dengan kontrol (6,67 vs 4,67, p=0,002).Diskusi: Terdapat penurunan intensitas nyeri yang signifikan pada kelompok yang diberikan r-TMS selama 10 siklus.Kata kunci: Central pain, NPRS, stroke, r-TMS

Author(s):  
Divya Jain ◽  
Swapna Jawade ◽  
Neha Chitale

Background: "Text neck" is a term coined to describe the posture created by leaning forward for lengthy periods of time, such as when reading and texting on a cellphone which has been linked to stress injuries. Neck pain, upper back discomfort, shoulder pain, frequent headaches, and greater curvature of the spine are all dangerous indications of text neck. According to a survey, 35% of smartphone users suffer from text neck syndrome. People between the ages of 15 and 18 are more likely to have neck pain. This protocol has been created that describes the design of comparative study to evaluate effectiveness of progressive resisted exercise along with conventional exercise and conventional exercise program alone in text neck syndrome. Methods: The participants (n=80) will be recruited in the study suffering from text neck syndrome and meeting the inclusion criteria. Two groups will be formed such that patients in group A will be treated with conventional therapy and group B will be treated with progressive resisted exercise (PRE) along with conventional therapy. The protocol will cover 4 weeks of treatment. In the rehabilitation period, we will evaluate the pain intensity, strength of neck muscles and functional activity. Our outcome measures will be- Numerical pain rating scale (NPRS) and Neck disability index (NDI). Discussion: Efficacy of the intervention will be evaluated by analyzing the pain intensity by using Numerical pain rating scale (NPRS) and level of functional disability by using Neck disability index (NDI). The result of the study will significantly provide affirmation on either using combination therapy of PRE with conventional exercise or conventional exercise alone.


2017 ◽  
Vol 10 (4) ◽  
pp. 862-864 ◽  
Author(s):  
Mélanie Cogné ◽  
Cédric Gil-Jardiné ◽  
Pierre-Alain Joseph ◽  
Dominique Guehl ◽  
Bertrand Glize

Pain ◽  
2001 ◽  
Vol 94 (2) ◽  
pp. 149-158 ◽  
Author(s):  
John T. Farrar ◽  
James P. Young ◽  
Linda LaMoreaux ◽  
John L. Werth ◽  
Michael R. Poole

2019 ◽  
Vol 1 (1) ◽  
pp. 22
Author(s):  
Evelin Malinti ◽  
Febri A Nabuasa

CRYOTHERAPY DAN INTENSITAS NYERI PADA INJEKSI INTRAKUTAN Abstrak Cryotherapy merupakan aplikasi terapi suhu rendah atau dingin yang digunakan untuk berbagai keperluan seperti mengurangi pembengkakan pada trauma, peradangan dan mengurangi nyeri. Cryotherapy juga telah digunakan untuk menangani nyeri pada prosedur penyuntikan seperti penyuntikan subkutan dan intravena. Secara khusus penelitian ini bertujuan untuk mengevaluasi perbedaan efek dari cryotherapy kering dan basah pada intensitas nyeri injeksi intrakutan. Metode: yang digunakan dalam penelitian ini adalah quasi ekperimen dengan post-test design. Pemilihan sample menggunakan teknik purposive sampling untuk memperoleh total 54 responden yang dibagi kedalam dua kelompok. Penelitian ini membandingkan intensitas nyeri kedua kelompok menggunakan numerical pain rating scale. Masing-masing kelompok mendapatkan aplikasi cryotherapy pada area penyuntikan selama 5 menit sebelum dilakukan injeksi intrakutan. Kelompok I diberikan aplikasi cryotherapy dalam bentuk es batu dalam plastik es yang dibungkus kantong kain. Kelompok II diberikan aplikasi washlap yang telah dicelupkan dalam air es. Hasil penelitian menunjukkan bahwa rata-rata intensitas nyeri pada kelompok I berada pada kategori nyeri sedang, dan kelompok II berada pada kategori nyeri berat terkontrol. Uji t-independen menunjukkan bahwa terdapat perbedaan signifikan pada intensitas nyeri diantara kedua kelompok (p<0.05). Dengan demikian aplikasi cryotherapy dengan es batu selama 5 menit lebih efektif mengurangi intensitas nyeri pada injeksi intrakutan. Aplikasi cryotherapy dapat dilakukan untuk mengurangi nyeri pada injeksi intrakutan. CRYOTHERAPY AND PAIN INTENSITY ON INTRACUTANEOUS INJECTION  Abstract Cryotherapy is an application of low or cold temperature therapy that is used for various purposes such as reducing swelling in trauma, inflammation and reducing pain. Cryotherapy has also been used to treat pain in injection procedures such as subcutaneous and intravenous injections. In particular, this study aimed to evaluate the differences in the effects of dry and wet cryotherapy on the pain intensity of intracutaneous injection. The method used in this study is quasi experiment with post-test design. The sample selection uses a purposive sampling technique to obtain a total of 54 respondents divided into two groups. This study compared the intensity of pain between the two groups using the numerical pain rating scale. Each group received an application of cryotherapy in the injection area for 5 minutes before intracutaneous injection. Group I was given the application of cryotherapy in the form of ice cubes in ice plastic wrapped in a cloth bag. Group II was given the washlap application which had been dipped in ice water. The results showed that the average pain intensity in group I was in the moderate pain category, and group II was in the category of heavily controlled pain. Independent t-test showed that there were significant differences in pain intensity between the two groups (p <0.05). Thus the application of cryotherapy with ice cube for 5 minutes is more effective in reducing pain intensity in intracutaneous injection. The application of cryotherapy can be done to reduce pain in intracutaneous injection.  


Pharmacology ◽  
2018 ◽  
Vol 101 (5-6) ◽  
pp. 290-297 ◽  
Author(s):  
Joana Tenreiro Pinto ◽  
Frederico C. Pereira ◽  
Maria C. Loureiro ◽  
Ricardo Gama ◽  
Hugo L. Fernandes

Background/Aims: Several guidelines for neuropathic pain management and various effective drugs are available; however, neuropathic pain remains undertreated. This retrospective study aimed to evaluate the efficacy of topical capsaicin 8% in peripheral neuropathic pain in a routine clinical setting. Methods: Therapeutic efficacy was evaluated through pain intensity, using numerical pain rating scale at baseline and 7–14 days after each treatment, and using pain treatment area (PTA) assessed immediately before each treatment. Results: A total of 43 patients with either post-herpetic neuralgia or post-traumatic/post-surgical neuropathic pain were enrolled. The median percentage reduction in numerical pain rating scale score and in PTA was –40.0 (–50.0 to –33.3; 95% CI, bootstrap) and –35.1 (–50.9 to 3.4; 95% CI, bootstrap), respectively. Pain intensity and PTA were equally improved and reduced in both treated conditions. Conclusion: This study suggests that topical capsaicin 8% reduces peripheral neuropathic pain as well as treatment pain area.


Author(s):  
Azza B. Hammad ◽  
Rasha E. Elsharkawy ◽  
Ghada S. Abdel Azim

Abstract Background Clinical applications of transcranial magnetic stimulation (TMS) have shown promising results in the treatment of headache disorders, with migraine being one of the most encountered. Objective To assess the role of low-frequency repetitive transcranial magnetic stimulation as a preventive treatment of migraine (with and without aura) and correlate the results with the serum level of the inflammatory biomarker (neurokinin A). Methods Forty patients, with age ranging from 15 to 55 years, diagnosed with migraine (30 migraine without aura and 10 with aura) and 20 apparently healthy individuals, who were age and sex matched with the patient group, were included in this study. A low-frequency (1 Hz) rTMS protocol was applied for all patients for five consecutive days interictally. Assessment of pain intensity using visual analogue scale and frequency and duration of attacks as well as number of pills taken by patients as an abortive treatment according to the Basic Diagnostic Headache Diary for 4 weeks before and 4 weeks after TMS sessions was done. In addition, the Migraine Disability Assessment scale (MIDAS) was applied to assess the severity and degree of disability caused by migraine. Measurement of neurokinin A serum level was done by using ELISA for all patients before and after TMS and for control group once. Results There was a significant reduction in pain intensity, frequency and duration of migraine attacks, migraine disability scores, and number of pills taken as abortive treatment for attacks after rTMS (P < 0.001). Also, serum level of neurokinin A in the patients was significantly reduced after rTMS (P < 0.001). Conclusion Low-frequency rTMS is an effective prophylactic treatment for migraine with and without aura.


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