Efficacy Analysis of Capsaicin 8% Patch in Neuropathic Peripheral Pain Treatment

Pharmacology ◽  
2018 ◽  
Vol 101 (5-6) ◽  
pp. 290-297 ◽  
Author(s):  
Joana Tenreiro Pinto ◽  
Frederico C. Pereira ◽  
Maria C. Loureiro ◽  
Ricardo Gama ◽  
Hugo L. Fernandes
Keyword(s):  
Neuropathic Pain ◽  
Pain Intensity ◽  
Rating Scale ◽  
Pain Treatment ◽  
Pain Rating ◽  
Treatment Area ◽  
Peripheral Neuropathic Pain ◽  
Numerical Pain Rating Scale ◽  
Topical Capsaicin ◽  
Pain Rating Scale

Background/Aims: Several guidelines for neuropathic pain management and various effective drugs are available; however, neuropathic pain remains undertreated. This retrospective study aimed to evaluate the efficacy of topical capsaicin 8% in peripheral neuropathic pain in a routine clinical setting. Methods: Therapeutic efficacy was evaluated through pain intensity, using numerical pain rating scale at baseline and 7–14 days after each treatment, and using pain treatment area (PTA) assessed immediately before each treatment. Results: A total of 43 patients with either post-herpetic neuralgia or post-traumatic/post-surgical neuropathic pain were enrolled. The median percentage reduction in numerical pain rating scale score and in PTA was –40.0 (–50.0 to –33.3; 95% CI, bootstrap) and –35.1 (–50.9 to 3.4; 95% CI, bootstrap), respectively. Pain intensity and PTA were equally improved and reduced in both treated conditions. Conclusion: This study suggests that topical capsaicin 8% reduces peripheral neuropathic pain as well as treatment pain area.

scholarly journals Effectiveness of Progressive Resisted Exercise along with Conventional Exercise and Conventional Exercise Program alone in Subjects with Text Neck Syndrome

2021 ◽  
pp. 536-542
Author(s):  
Divya Jain ◽  
Swapna Jawade ◽  
Neha Chitale
Keyword(s):  
Neck Pain ◽  
Pain Intensity ◽  
Conventional Therapy ◽  
Rating Scale ◽  
Neck Disability Index ◽  
Exercise Program ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Neck Disability ◽  
Pain Rating Scale

Background: "Text neck" is a term coined to describe the posture created by leaning forward for lengthy periods of time, such as when reading and texting on a cellphone which has been linked to stress injuries. Neck pain, upper back discomfort, shoulder pain, frequent headaches, and greater curvature of the spine are all dangerous indications of text neck. According to a survey, 35% of smartphone users suffer from text neck syndrome. People between the ages of 15 and 18 are more likely to have neck pain. This protocol has been created that describes the design of comparative study to evaluate effectiveness of progressive resisted exercise along with conventional exercise and conventional exercise program alone in text neck syndrome. Methods: The participants (n=80) will be recruited in the study suffering from text neck syndrome and meeting the inclusion criteria. Two groups will be formed such that patients in group A will be treated with conventional therapy and group B will be treated with progressive resisted exercise (PRE) along with conventional therapy. The protocol will cover 4 weeks of treatment. In the rehabilitation period, we will evaluate the pain intensity, strength of neck muscles and functional activity. Our outcome measures will be- Numerical pain rating scale (NPRS) and Neck disability index (NDI). Discussion: Efficacy of the intervention will be evaluated by analyzing the pain intensity by using Numerical pain rating scale (NPRS) and level of functional disability by using Neck disability index (NDI). The result of the study will significantly provide affirmation on either using combination therapy of PRE with conventional exercise or conventional exercise alone.

Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale

Pain ◽  
2001 ◽  
Vol 94 (2) ◽  
pp. 149-158 ◽  
Author(s):  
John T. Farrar ◽  
James P. Young ◽  
Linda LaMoreaux ◽  
John L. Werth ◽  
Michael R. Poole
Keyword(s):  
Chronic Pain ◽  
Pain Intensity ◽  
Rating Scale ◽  
Clinical Importance ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale

scholarly journals Cryotherapy Dan Intensitas Nyeri Pada Injeksi Intrakutan

2019 ◽  
Vol 1 (1) ◽  
pp. 22
Author(s):  
Evelin Malinti ◽  
Febri A Nabuasa
Keyword(s):  
Pain Intensity ◽  
Rating Scale ◽  
Test Design ◽  
Pain Rating ◽  
Purposive Sampling ◽  
Numerical Pain Rating Scale ◽  
Group I ◽  
Post Test ◽  
Intracutaneous Injection ◽  
Pain Rating Scale

CRYOTHERAPY DAN INTENSITAS NYERI PADA INJEKSI INTRAKUTAN Abstrak Cryotherapy merupakan aplikasi terapi suhu rendah atau dingin yang digunakan untuk berbagai keperluan seperti mengurangi pembengkakan pada trauma, peradangan dan mengurangi nyeri. Cryotherapy juga telah digunakan untuk menangani nyeri pada prosedur penyuntikan seperti penyuntikan subkutan dan intravena. Secara khusus penelitian ini bertujuan untuk mengevaluasi perbedaan efek dari cryotherapy kering dan basah pada intensitas nyeri injeksi intrakutan. Metode: yang digunakan dalam penelitian ini adalah quasi ekperimen dengan post-test design. Pemilihan sample menggunakan teknik purposive sampling untuk memperoleh total 54 responden yang dibagi kedalam dua kelompok. Penelitian ini membandingkan intensitas nyeri kedua kelompok menggunakan numerical pain rating scale. Masing-masing kelompok mendapatkan aplikasi cryotherapy pada area penyuntikan selama 5 menit sebelum dilakukan injeksi intrakutan. Kelompok I diberikan aplikasi cryotherapy dalam bentuk es batu dalam plastik es yang dibungkus kantong kain. Kelompok II diberikan aplikasi washlap yang telah dicelupkan dalam air es. Hasil penelitian menunjukkan bahwa rata-rata intensitas nyeri pada kelompok I berada pada kategori nyeri sedang, dan kelompok II berada pada kategori nyeri berat terkontrol. Uji t-independen menunjukkan bahwa terdapat perbedaan signifikan pada intensitas nyeri diantara kedua kelompok (p<0.05). Dengan demikian aplikasi cryotherapy dengan es batu selama 5 menit lebih efektif mengurangi intensitas nyeri pada injeksi intrakutan. Aplikasi cryotherapy dapat dilakukan untuk mengurangi nyeri pada injeksi intrakutan. CRYOTHERAPY AND PAIN INTENSITY ON INTRACUTANEOUS INJECTION  Abstract Cryotherapy is an application of low or cold temperature therapy that is used for various purposes such as reducing swelling in trauma, inflammation and reducing pain. Cryotherapy has also been used to treat pain in injection procedures such as subcutaneous and intravenous injections. In particular, this study aimed to evaluate the differences in the effects of dry and wet cryotherapy on the pain intensity of intracutaneous injection. The method used in this study is quasi experiment with post-test design. The sample selection uses a purposive sampling technique to obtain a total of 54 respondents divided into two groups. This study compared the intensity of pain between the two groups using the numerical pain rating scale. Each group received an application of cryotherapy in the injection area for 5 minutes before intracutaneous injection. Group I was given the application of cryotherapy in the form of ice cubes in ice plastic wrapped in a cloth bag. Group II was given the washlap application which had been dipped in ice water. The results showed that the average pain intensity in group I was in the moderate pain category, and group II was in the category of heavily controlled pain. Independent t-test showed that there were significant differences in pain intensity between the two groups (p <0.05). Thus the application of cryotherapy with ice cube for 5 minutes is more effective in reducing pain intensity in intracutaneous injection. The application of cryotherapy can be done to reduce pain in intracutaneous injection.  

scholarly journals PENGARUH REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (r-TMS) TERHADAP INTENSITAS NYERI PENDERITA CENTRAL POST-STROKE PAIN (CPSP)

2018 ◽  
Vol 35 (4) ◽  
Author(s):  
Dody Perdana Goenadhi ◽  
Jumraini Tammasse ◽  
David Gunawan
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Pain Intensity ◽  
Magnetic Stimulation ◽  
Rating Scale ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Central Pain ◽  
Pain Rating ◽  
Post Stroke ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale

  EFFECTS OF REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (r-TMS) TOWARDS PAIN INTENSITY IN PATIENTS WITH CENTRAL POST-STROKE PAIN (CPSP)ABSTRACTIntroduction: About 2,7% patients have experienced central post-stroke pain (CPSP) after stroke attack. Repetitive transcranial magnetic stimulation (r-TMS) is a nonpharmacological method to overcome CPSP.Aims: To determine the effectiveness of r-TMS to reduce pain intensity in patients with CPSP.Methods: Randomized-controlled trial in Wahidin Sudirohusodo hospital and Inggit clinic from December 2017 until May 2018. Subjects were divided to 2 groups; control, who received standard therapy for CPSP, and treatment, who received standard therapy for CPSP and r-TMS. Repetitive transcranial magnetic stimulation was done using 2000 pulse and 10Hz frequency. Pain intensity was measured with Numerical Pain Rating Scale (NPRS) at baseline, after r-TMS until day 10. Data analysis was done by Mann-Whitney test.Results: As much as 30 subjects were divided into 2 groups (15 control and 15 treatment). The difference in NPRS score after 10 days of treatment was statistically higher in the treatment group compared to the control (6,67 vs 4,67, p=0,002).Discussion: There was a significant reduction in pain intensity in the group given r-TMS for 10 cycles.Keywords: Central pain, NPRS, r-TMS, strokeABSTRAKPendahuluan: Sebanyak 2,7% pasien mengalami central post-stroke pain (CPSP) setelah serangan. Efektivitas repetitive transcranial magnetic stimulation (r-TMS) merupakan salah satu metoda nonfarmakologis untuk mengatasi CPSP.Tujun: Mengetahui efektivitas repetitive transcranial magnetic stimulation (r-TMS) terhadap penurunan intensitas nyeri pada penderita CPSP.Metode: Uji klinis terandomisasi di RSUP Dr. Wahidin Sudirohusodo dan Klinik Inggit dari Desember 2017 hingga Mei 2018. Subjek dibagi menjadi 2 kelompok, kelompok kontrol yang mendapat terapi standar dan kelompok perlakuan yang ditambahkan r-TMS. Repetitive transcranial magnetic stimulation dilakukan sebanyak 2000 pulse dengan frekuensi 10Hz. Nyeri diukur dengan Numerical Pain Rating Scale (NPRS) sebelum dan pascaterapi hingga hari ke-10. Analisis data dilakukan dengan uji Mann-Whitney.Hasil: Didapatkan 30 subjek yang dibagi menjadi 2 kelompok (15 kontrol dan 15 perlakuan). Selisih skor NPRS setelah sepuluh hari terapi lebih besar secara signifikan pada kelompok perlakuan dibandingkan dengan kontrol (6,67 vs 4,67, p=0,002).Diskusi: Terdapat penurunan intensitas nyeri yang signifikan pada kelompok yang diberikan r-TMS selama 10 siklus.Kata kunci: Central pain, NPRS, stroke, r-TMS

scholarly journals Effectiveness of Strengthening and Aerobic Exercises among Geriatrics with Arthritis

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 593-598
Author(s):  
Tamilselvi S ◽  
Anshu Gloria Ekka ◽  
Arul Jothi L
Keyword(s):  
Aerobic Exercise ◽  
Rating Scale ◽  
Nursing Intervention ◽  
Control Group ◽  
Research Approach ◽  
Intensity Level ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale ◽  
Experimental Group

Joint inflammation might be a term regularly acclimated mean any confusion that influences joints. Manifestations for the most part, incorporate joint torment and firmness. Different manifestations may incorporate redness, warmth, growing, the diminished scope of movement of the influenced joints. The aim of the study is to determine the effectiveness of strengthening and aerobic exercise among geriatrics with arthritis. A quantitative research approach with a quasi-experimental research design was used for the present study. A total of 60 arthritis clients who fall in the inclusion criteria were selected by purposive sampling technique, among which 30 samples were in the experimental group and 30 in the control group. The data were collected for both the groups, followed by the pre-test was conducted on the 1st day, the intensity level of pain was assessed by the numerical pain rating scale followed by the exercises which are effective in arthritis are a range of motion exercise, strengthening exercises (hand towel knee exercises, knee flexion, long arc quads), aerobic exercise (brisk walking) was initiated only in the experimental group. The post-test was conducted on 7th day and the level of pain was assessed by a numerical pain rating scale in both the groups. The results revealed that there was a significant reduction in the level of pain at p<0.0001 after the intervention among the experimental group. Thus, the study proves that strengthening and aerobic exercises can be used as an effective nursing intervention for reducing the arthritis pain among the geriatrics and it is easily applicable exercises, and also considered as a less cost-effective. These exercises can be practiced at home without any stress or harm and it has less side effect as compared to that of pharmacological interventions. 

scholarly journals Effectiveness of Cryotherapy on Pain Reduction During Arteriovenous Fistula Puncture Among Patients Undergoing Hemodialysis

2020 ◽  
Vol 11 (3) ◽  
pp. 4314-4317
Author(s):  
Thamu Priyadharshini N T
Keyword(s):  
Rating Scale ◽  
Life Support ◽  
Pain Reduction ◽  
Control Group ◽  
Pain Rating ◽  
Av Fistula ◽  
Numerical Pain Rating Scale ◽  
Significant Difference ◽  
Pain Rating Scale ◽  
Experimental Group

Dialysis is performed as critical life support when the patient is suffering acute and chronic kidney failure. The study focus on to determine effectiveness of on pain reduction during AV fistula puncture among patients undergoing . The population comprised of patients in . Experimental Research design was utilized for this study. The investigators assess the pain on AV fistula puncture among the patients with the assistance of numerical pain rating scale, Sixty samples (30 experimental group and 30 control group)were selected by probability simple random (Numerical table method)sampling technique, the data was gathered through the Numerical Pain Rating scale and demographic variables. The pain on AV fistula puncture of the experimental group and control group were calculated by paired’ test for experimental group (‘t’ = 18) and in control group, (‘t’ =1.5). This proves that there is a significant difference in test and post test levels of pain on AV fistula puncture in the experimental group at 0.05 levels. It indicated that the given was effective. The implication of the findings indicated that given was effective for pain reduction during AV fistula puncture among patients. : , pain on AV fistula puncture, patients. implication of the findings indicated that given was effective for pain reduction during AV fistula puncture among patients.

scholarly journals EFEKTIVITAS DAN EFEK SAMPING PENGGUNAAN GABAPENTIN PADA PASIEN NEUROPATI DIABETIK DI RSUP DR. WAHIDIN SUDIROHUSODO MAKASSAR

2018 ◽  
Vol 22 (2) ◽  
pp. 44-47
Author(s):  
Zhulhajsyirah Zhulhajsyirah ◽  
Elly Wahyudin ◽  
Jumriani Tammas
Keyword(s):  
Rating Scale ◽  
P Value ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale

Penelitian ini bertujuan untuk mengetahui dan menganalisis efektivitas  penggunaan gabapentin  terhadap penurunan derajat nyeri pada  pasien neuropati diabetik di  RSUP Wahidin Sudirohusodo Makassar  yang diukur dengan menggunakan instrumen  Numerical Pain Rating Scale (NPRS) efek samping  penggunaan  gabapentin   pada  pasien neuropati diabetik di  RSUP DR. Wahidin Sudirohusodo Makassar. Penelitian ini dilaksanakan di Poliklinik Saraf dan Poliklinik Endokrin Instalasi Rawat Jalan RSUP DR. Wahidin Sudirohusodo Makassar pada bulan april-juni 2018. Jenis penelitian ini adalah penelitian observasional non eksperimental dengan  desain penelitian  cros sectional. Metode yang digunakan dalam penelitian ini adalah dengan melakukan wawancara dan pengukuran skala nyeri pada pasien neuropati diabetik. Data dianalisis dengan menggunakan analisis statistik uji Wicoxon Signed Ranks Test. Hasil penelitian menunjukkan bahwa efek terapi gabapentin sebelum dan sesudah   pemberian pada 21 pasien neuropati diabetik menunjukkan adanya penurunan skala nyeri  dengan penurunan rata-rata sebesar 2,14 dengan nilai  p-value<0,05 yang berarti  berbeda secara signifikan dalam menurunkan nyeri neuropati. Sedangkan Efek Samping yang terjadi setelah pemberian gabapentin yaitu, mengantuk dan pusing 14%, mengantuk 29%, pusing 5% dan tidak mengalami efek samping 52%.

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