scholarly journals An Exploratory Study of Okara Product on Postprandial Blood Glucose and Serum Insulin Responses

2018 ◽  
Vol 76 (6) ◽  
pp. 156-162
Author(s):  
Satoko Noguchi ◽  
Kohei Suruga ◽  
Kumiko Nakai ◽  
Akihiro Murashima ◽  
Yoshihiro Koshino-Kimura ◽  
...  
Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1115 ◽  
Author(s):  
Mariana O. C. Coelho ◽  
Alistair J. Monteyne ◽  
Ishara D. Kamalanathan ◽  
Vesna Najdanovic-Visak ◽  
Tim J. A. Finnigan ◽  
...  

Circulating uric acid concentrations have been linked to various metabolic diseases. Consumption of large boluses of nucleotides increases serum uric acid concentrations. We investigated the effect of a nucleotide-rich mixed meal on postprandial circulating uric acid, glucose, and insulin responses. Ten healthy adults participated in a randomised, controlled, double-blind, crossover trial in which they consumed a mixed-meal containing either nucleotide-depleted mycoprotein (L-NU) or high-nucleotide mycoprotein (H-NU) on two separate visits. Blood samples were collected in the postabsorptive state and throughout a 24 h postprandial period, and were used to determine circulating uric acid, glucose, and insulin concentrations. Mixed meal ingestion had divergent effects on serum uric acid concentrations across conditions (time x condition interaction; P < 0.001), with L-NU decreasing transiently (from 45 to 240 min postprandially) by ~7% (from 279 ± 16 to 257 ± 14 µmol·L−1) and H-NU resulting in a ~12% increase (from 284 ± 13 to 319 ± 12 µmol·L−1 after 210 min), remaining elevated for 12 h and returning to baseline concentrations after 24 h. There were no differences between conditions in blood glucose or serum insulin responses, nor in indices of insulin sensitivity. The ingestion of a nucleotide-rich mixed-meal increases serum uric acid concentrations for ~12 h, but does not influence postprandial blood glucose or serum insulin concentrations.


1989 ◽  
Vol 61 (2) ◽  
pp. 285-290 ◽  
Author(s):  
K. M. Cunningham ◽  
N. W. Read

1. Three studies were carried out in each of six normal volunteers to investigate how lipid, when given at different stages during the course of a meal, affects gastric emptying and postprandial blood glucose and insulin concentrations.2. The control meal consisted of 300 ml beef consommé (50 kJ, 12 kcal), followed 20 min later by 300 g mashed potato (908 kJ, 217 kcal). In the two test meals, 60 g margarine were incorporated into either the soup or the mashed potato.3. The addition of margarine to either component of the meal delayed gastric emptying of the mashed potato (P< 0.05), but the pattern varied according to the component to which the fat was added.4. Incorporation of fat into the soup increased the lag phase (P< 0.05) but did not influence the slope of emptying of the mashed potato, while incorporation of fat into the mashed potato reduced the slope of emptying of the mashed potato (P< 0.05) but did not influence the lag phase.5. Addition of fat to either component of the meal reduced postprandial blood glucose (P< 0.05) and insulin responses, but when the fat was incorporated in the soup, peak glucose and insulin responses were delayed as well (P< 0.05).6. The results show that the effect of fat on gastric emptying and absorption of nutrients depends on when, in relation to the other components of the meal, the fat is consumed.


2020 ◽  
Vol 88 ◽  
pp. 102963
Author(s):  
Tayler L. Hansen ◽  
Ellen M. Rankins ◽  
Jill M. Bobel ◽  
Meagan McKinney ◽  
Timothy J. Hackmann ◽  
...  

2000 ◽  
Vol 84 (1) ◽  
pp. 19-23 ◽  
Author(s):  
P. J. Wood ◽  
M. U. Beer ◽  
G. Butler

Data from clinical studies established that there was an inverse linear relationship between measures of postprandial blood glucose and insulin responses to an oral glucose load, consumed in a drink, and the logarithm of viscosity of the drink. These data have been re-analysed using concentration and molecular weight as the dependent variables. Molecular weight (M) of the β-glucans used was determined using high-performance size exclusion chromatography equipped with a triple detector system of right angle light scattering, viscometry and refractive index. A significant relationship between changes in peak blood glucose and a combination of logarithm of the concentration and logarithm of M was found.


2020 ◽  
Author(s):  
Kathy Musa-Veloso ◽  
Daniel Noori ◽  
Carolina Venditti ◽  
Theresa Poon ◽  
Jodee Johnson ◽  
...  

ABSTRACT Background Oats are a whole grain cereal with potentially favorable effects on the postprandial glycemic response; however, the effects of oat processing on these glycemic benefits are not well understood. Objectives The study objective was to determine the effects of differently processed oats on the postprandial blood glucose and insulin responses relative to refined grains. Methods Eleven electronic databases were systematically searched to identify studies published up to and including May 2019. Randomized controlled trials comparing the postprandial blood glucose and insulin responses to oats compared with any refined grain were included, so long as the available carbohydrate content of the test meals was similar. Pooled effect sizes were computed using the difference in incremental area under the curves for blood glucose and insulin following the consumption of oats compared with the refined grain control. Results Ten publications were included, with intact oat kernels studied in 3 comparisons, thick oat flakes (&gt;0.6 mm) in 7 comparisons, and thin/quick/instant oat flakes (≤0.6 mm) in 6 comparisons. Compared with the consumption of the refined grain control, the consumption of intact oat kernels was associated with significant reductions in postprandial blood glucose (−45.5 mmol x min/L; 95% CI: −80.1, −10.9 mmol x min/L; P = 0.010) and insulin (−4.5 nmol x min/L; 95% CI: −7.1, −1.8 nmol x min/L; P = 0.001) responses; the consumption of thick oat flakes was associated with significant reductions in postprandial blood glucose (−30.6 mmol x min/L; 95% CI: −40.4, −20.9 mmol x min/L; P &lt; 0.001) and insulin (−3.9 nmol x min/L; 95% CI: −5.3, −2.5 nmol x min/L; P &lt; 0.001) responses; but, the consumption of thin/quick/instant oat flakes was not associated with any effects on the postprandial blood glucose and insulin responses. Conclusions A disruption in the structural integrity of the oat kernel is likely associated with a loss in the glycemic benefits of oats.


1987 ◽  
Vol 72 (2) ◽  
pp. 209-216 ◽  
Author(s):  
I. McL. Welch ◽  
C. Bruce ◽  
S. E. Hill ◽  
N. W. Read

1. Infusion of lipid into the ileum delays the transit of a meal through the stomach and small intestine and could therefore influence the rate and degree of nutrient absorption. 2. Experiments were carried out on human volunteers to investigate the effect of infusion of lipid into either the duodenum or ileum on blood glucose, insulin and gastric emptying after ingestion of a mashed potato meal. 3. Infusions of lipid into either the duodenum or the ileum significantly reduced or abolished the immediate postprandial rises in blood glucose and insulin and significantly delayed gastric emptying. Blood glucose and insulin rose shortly after the lipid infusion terminated. 4. Addition of corn oil to a meal of mashed potato also reduced blood glucose and insulin and delayed gastric emptying. 5. Intestinal lipid can thus modify the glycaemic and insulinaemic responses to a meal, and this modulation probably explains the reduced metabolic responses to a meal containing fat compared with a fat free meal. This principle could be of value in the dietary control of diabetes mellitus.


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