scholarly journals Nontuberculous mycobacteria and bronchiectasis

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Oxana Munteanu ◽  
◽  
Victor Botnaru ◽  
Keyword(s):  
Pulmonary Disease ◽  
Patient Management ◽  
Nontuberculous Mycobacteria ◽  
Epidemiological Data ◽  
Republic Of Moldova ◽  
Diagnosis And Management ◽  
Radiological Features ◽  
The Republic ◽  
Optimal Patient Management

Nontuberculous mycobacterial pulmonary disease is an emerging multidisciplinary problem during the last decades, despite the lack of epidemiological data in most countries, including the Republic of Moldova. An increasing interest has been observed in evaluating nontuberculous mycobacteria (NTM) in patients with bronchiectasis, although the dilemma of which of these diseases comes first remains unresolved. This paper reviews several aspects of the correlations between NTM and bronchiectasis including pathogenesis, radiological features, diagnosis and management, emphasizing the necessity for clinicians to have sufficient familiarity of the mycobacteria types to provide optimal patient management.

Prevalence of Multiple Sclerosis in the Republic of Moldova

2016 ◽  
Vol 46 (3) ◽  
pp. 166-172 ◽  
Author(s):  
Cristina Marcoci ◽  
Vitalie Lisnic ◽  
Mihail Gavriliuc ◽  
Olesea Odainic ◽  
Marina Sangheli ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Disease Burden ◽  
Nationwide Survey ◽  
Epidemiological Data ◽  
Age Group ◽  
Disease Modifying Drugs ◽  
Republic Of Moldova ◽  
Mcdonald Criteria ◽  
The Republic ◽  
Crude Prevalence

Background: The occurrence of multiple sclerosis (MS) increases in populations featuring both high and low disease burden, and variations across regions at the same latitude are reported. MS epidemiological data in Eastern Europe are scarce and out of date. We report on sex- and age-specific prevalence of MS in the Republic of Moldova. Methods: Benefitting from a nationwide survey aimed to quantify the MS burden in Moldovans (3,559,541 population in 2012), multiple epidemiological sources were scrutinized. Results: On prevalence day, December 31, 2012, 747 MS patients (McDonald criteria) resided in the study area, yielding a crude prevalence of 20.9 per 100,000 (95% CI 14.7-27.1), 25.7 (95% CI 20.5-30.5) in women and 15.8 (95% CI 12.2-19.3) in men (F:M ratio of 1.63), and standardized estimates of 20.2, 24.3 and 15.5 per 100,000, respectively. Prevalence was highest in the age group 40-49 years (43.9 per 100,000) and higher in rural (72.6%) than in urban (27.4%) areas. Conclusions: This is the first report on sex- and age-specific prevalence of MS in the Republic of Moldova, which was lower than in Europe on average, but consistent with that of neighboring countries, Romania and Ukraine. Moldovans represent a population wherein MS natural history is not yet influenced by use of disease-modifying drugs.

scholarly journals First report of canine ocular thelaziosis in the Republic of Moldova

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Mirabela Oana Dumitrache ◽  
Angela Monica Ionică ◽  
Eugeniu Voinițchi ◽  
Nicolai Chavdar ◽  
Gianluca D’Amico
Keyword(s):  
Epidemiological Data ◽  
Emerging Pathogens ◽  
Intact Male ◽  
Public Health Perspective ◽  
Veterinary Clinic ◽  
First Report ◽  
Transmission Cycle ◽  
Republic Of Moldova ◽  
History Of ◽  
The Republic

Abstract Background Countries of eastern Europe are considered, due to several risk factors, more vulnerable to infections with newly (re)emerging pathogens. During the last decade, in several European countries, reports of autochthonous cases of ocular thelaziosis due to Thelazia callipaeda have been published, posing a great concern from both veterinary and public health perspective. However, in the Republic of Moldova only limited epidemiological data are available regarding zoonotic vector-borne pathogens and, until now, no data exist on the zoonotic nematode T. callipaeda. Methods In September 2018, an 11-year-old dog, mixed-breed, intact male was referred to a private veterinary clinic from Chișinău, Republic of Moldova, with a history of 2 weeks of an ocular condition affecting the right eye. The ophthalmological exam revealed the presence of nematode parasites in the conjunctival sac and under the third eyelid. The collected parasites were identified by morphological techniques and molecular analysis. Results A total of 7 nematodes were collected, and 5 females and 2 males of T. callipaeda were identified morphologically. The BLAST analysis confirmed the low genetic variability of this parasite in Europe. The travel history of the patient allowed us to confirm the autochthonous character of the case. Conclusions To the best of our knowledge, this is the first report of thelaziosis in dogs from the Republic of Moldova, which confirms the spreading trend of T. callipaeda and the existence of an autochthonous transmission cycle of this zoonotic parasite in the country.

Promoting and supporting physical activity and sport among young people in the Republic of Moldova

2018 ◽  
Vol 13 (3) ◽  
pp. 158-164
Author(s):  
Serghei Cebanu ◽  
◽  
Mariana Tutunaru ◽  
Raisa Deleu ◽  
Angela Cazacu-Stratu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Young People ◽  
Republic Of Moldova ◽  
The Republic

Republic of Moldova in the Context of Regional Security Challenges in Eastern Europe

2018 ◽  
pp. 299-304
Author(s):  
Stefan Tibuleac
Keyword(s):  
Eastern Europe ◽  
Security Policy ◽  
Security System ◽  
Regional Security ◽  
Strategic Uncertainty ◽  
European Security ◽  
Republic Of Moldova ◽  
The Republic ◽  
The Impact

This article analyzes the most current security issues for the Republic of Moldova that are part of the regional security context of Eastern Europe –the region that can be considered the epicenter of international tensions through which the„geopolitical line of fracture”passes. The geographical position of the Republic of Moldova makes this state particularly sensitive to any negative trends in theregion. Growing of international tensions creates security threats and complicates economic development. From a historical point of view, Moldova has repeatedly fallen victim by the confrontation of the great powers. Therefore, the Republic of Moldova has a vital interest in preventing a new conflict in Eastern Europe. This article is based on a number of assumptions made by changes in the European security environment, such as the „shift of weight” to the East, strategic uncertainty, increasing the role of non-state actors, the situation in eastern Ukraine, etc. Based on these assumptions, this article makes an attempt to outline the potential role of the Republic of Moldova in the Eastern European security system, taking into account the desideratum for integration of the republic into the European Union. Other relevant factors will be taken into account for shaping the role of the Republic of Moldova in the European security system, namely: the security deficit; the impact of NATO and EU security policy; the rebirth of the project to create a regional defense alliance, etc. This article will largely take into account the military aspects of security. Keywords: Republic of Moldova, national security, Eastern Europe, NATO, Intermarium, defence, threats, risks, challenges

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