Chemical Composition of Oroxylum indicum: A Review

Author(s):  
Yogita Chowdhary

Root bark of sonapatha is an astringent, tonic, anti-diarrhoeal, diuretic, anodyne, and is used to cure dropsy. It is an ingredient of ‘dashamoolarishta’ of Ayurvedic medicine. Stem bark is anti-rheumatic. An infusion of bark powder is diaphoretic. Tender fruits have spas- molytic, carminative, and stomachic properties, while seeds are purgative.it is a medium-sized, soft-wooded tree attaining a height of 10–16 m. Stem bark is dull brown in colour; leaves are broad, 60–120 cm in length and pinnately compound. Leaflets are ovate, wavy, and acuminate. Leaf fall occurs during winter season (January) each year. The tree is recognized by ternately bipinnate leaves. The root bark contains chrysin, baicalein, dehydrobaicalein, and orozylin. Stem bark possesses flavonoids such as oroxylin, baicalein, scutelarin and 7-rutinoside, chrysin, and p-coumaric acid. Heartwood yields β-sitosterol and isoflavone-prunetin. Root bark of sonapatha is an astringent, tonic, anti-diarrhoeal, diuretic, anodyne, and is used to cure dropsy. It is an ingredient of ‘dashamoolarishta’ of Ayurvedic medicine. Stem bark is anti-rheumatic. An infusion of bark powder is diaphoretic. Tender fruits have spas- molytic, carminative, and stomachic properties, while seeds are purgative. It is a medium-sized, soft-wooded tree attaining a height of 10–16 m. Stem bark is dull brown in colour; leaves are broad, 60–120 cm in length and pinnately compound. Leaflets are ovate, wavy, and acuminate. Leaf fall occurs during winter season (January) each year. The tree is recognized by ternately bipinnate leaves. The root bark contains chrysin, baicalein, dehydrobaicalein, and orozylin. Stem bark possesses flavonoids such as oroxylin, baicalein, scutelarin.

2021 ◽  
Vol 16 (3) ◽  
Author(s):  
Sarvesh Kumar ◽  
Renu Chaudhary ◽  
Prashant Arya ◽  
Sanjeev Kumar ◽  
Payal Verma ◽  
...  

Oroxylumindicum is a night bloomer and is pollinated naturally by bats. O. indicum, is used as one of the important ingredients in most commonly used Ayurvedic preparation, named as “Dasamula”. Stem bark has anti-rheumatic properties. Bark powder infusion are diaphoretic. The Tender fruits are spasmodic carminative, and stomachic while the seeds are purgative. Root bark of sonapatha is an astringent, tonic, anti-diarrhoeal, diuretic, anodyne, and is used to cure dropsy. The Flavonoids Chrysin, oroxylin-A, Scutella in and baicalein have been found in the stem bark and leaves of this plant. This plant’s seed are said to carry ellagic acid. In the current scenario, the investigation’s scope is critical for commercializing this plant and knowing the physiological function of bioactive chemicals during the development of diverse organs. It may allow for the standardization of physiological maturity, which is necessary for getting high-quality raw materials for the design and manufacture of health-beneficial medications.


2019 ◽  
Vol 35 (6) ◽  
pp. 1678-1689 ◽  
Author(s):  
Kafui Kpegba ◽  
Kodjo Eloh ◽  
Kodjo Selom Evenamede ◽  
Yaovi-Gameli Afanyibo ◽  
Abdelhakim Elomri ◽  
...  

In Togo, the abusive use of the root of Cassia sieberiana D.C. in traditional medicine, contributes gradually to the rarefaction of the species. The general objective of this study is to promote the use of vital organs of Cassia sieberiana in traditional medicine in Togo. The identification of secondary metabolites of the extracts (cyclohexane, dichloromethane and methanol) was carried out by GC-MS and by CL-MS / MS. The antibiotic susceptibility test was performed according to the well diffusion method and the MICs and MBCs according to the tube dilution method. Compounds such as sitosterol α-acetate, β-sitosterol, emodin, chaetochromine, luteolin, (±) -catechin, naringenin 5-O-rhamnoside, guibourtinidol- (4 alpha-> 6) -catechin and (-) - epiafzelechin are found in the root and in the stem bark. The identified molecules give the different methanolic extracts, an antibacterial effect on all the germs tested. At the end of this study, it appears that the chemical composition of the stem bark is almost similar to that of the root bark. The leaves would be better placed for the treatment of bacteria tested.


2021 ◽  
pp. 1-7
Author(s):  
Didjour Albert Kambiré ◽  
Jean Brice Boti ◽  
Zana Adama Ouattara ◽  
Acafou Yapi Thierry ◽  
Nelly Barat ◽  
...  

2015 ◽  
Vol 110 ◽  
pp. 36-44 ◽  
Author(s):  
Jun Tao ◽  
Leiming Zhang ◽  
Jian Gao ◽  
Han Wang ◽  
Faihe Chai ◽  
...  

2011 ◽  
Vol 1 (3) ◽  
pp. 152-157
Author(s):  
Vimal Kumar ◽  
A. K. Chaurasia ◽  
Ashok Naglot ◽  
Reji Gopalakrishnan ◽  
B. J. Gogoi ◽  
...  

The antioxidant activity of extracts of Oroxylum indicum stem bark wasevaluated using different methods. The ethyl acetate extract (EAE) showedthe lowest IC50 value (0.76 mg/ml) with the highest inhibition of DPPH. In theFRAP assay, the hexane extract (HE) showed the highest ferric reducing abilitywhereas the EAE showed better antioxidant ability with lowest IC50 value(0.80mg/ml) in βCL assay. The EAE and HE showed highest ascorbic acidequivalent (6.60 ± 0.22) and trolox equivalent (2.04 ± 0.07) values in antioxidativecapacity of ACW and ACL in PCL assay. During antimicrobial evaluationHE, Chloroform extract (CE) and EAE were found effective against thetested bacteria while the water extract (WE) showed better activity (14.25 ±0.478) against yeast.


Author(s):  
Arunodaya H. S. ◽  
Krishna V. ◽  
Shashikumar R. ◽  
Girish Kumar K.

<p><strong>Objective: </strong>To evaluate the chemical composition, antibacterial and antioxidant properties of stem bark essential oil of <em>Litsea glutinosa </em>C. B. Rob.</p><p><strong>Methods: </strong>The essential oil isolated from stem bark of <em>L. glutinosa </em>and their chemical composition was analyzed by gas chromatography coupled with mass spectrometry detector. The <em>in vitro </em>antibacterial activity of the stem bark essential oil was investigated against eight human pathogenic bacterial clinical isolates using agar disc diffusion method and MIC value was determined by modified resazurin microtitre-plate assay. The antioxidant activity of essential oil was measured by 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH), 2, 2-azinobis-3-ethylbenzothiazoline-6-sulphonate radical cation (ABTS) and β-carotene bleaching assay.</p><p><strong>Results: </strong>GC-MS analysis of stem bark essential oil resulted in the identification of 37 compounds, off which 9,12-octadecadienoic acid (62.57%), hexadecanoic acid (12.68%), stigmast-5-en-3-ol (6.87%) and vitamin E (2.51%) were the main constituents representing 84.63% of the oil. The determination of <em>in vitro</em> antibacterial activity of stem bark essential oil resulted in significant inhibition zone (15.00±0.57 mm) and MIC value (0.15±0.15×10<sup>-2</sup> mg/ml) against the pathogenic bacteria <em>Vibrio cholera</em> followed by <em>Pseudomonas aeruginosa</em> and <em>Salmonella typhi. </em>The results of DPPH radical scavenging (IC<sub>50</sub>:4.540±0.06 µg/ml), ABTS (IC<sub>50</sub>:256.02±0.06 µg/ml) and β-carotene bleaching assay (%I: 78.51±0.42 <strong>%</strong>) showed significant <em>in vitro</em> antioxidant property.</p><p><strong>Conclusion: </strong><em>L. glutinosa</em> stem bark essential oil showed potential antibacterial activity against the <em>Vibrio cholera</em>. The results of this investigation supported the ethnomedical claim of essential oil as a demulcent, antidiarrheal and antioxidant drug.</p>


Author(s):  
Thomas S. K. ◽  
George E. ◽  
Kunjumon M. ◽  
Thankamani I.

Alstonia venenata R. Br. belonging to the family Apocynaceae is a tall evergreen shrub distributed throughout Peninsular India. Stem-bark, root-bark, fruits and leaves are used by many tribal communities and also in Ayurveda. The study investigates the phytochemical composition of hexane, butanol, methanol and water extracts of Alstonia venenata fruits and flowers as well as the TLC profile of hexane extracts of fruits and flowers. Quantitative data of the wet and dry weight, yields from different solvent fractions and percentage yields were noted. The phytochemical analysis revealed the presence of secondary metabolites such as alkaloids, steroids, terpenoids, saponins, flavonoids, tannins and phenolic compounds from the various extracts. Alkaloids were present in all the fractions tested. Methanol extracts of fruits and flowers showed the presence of major phytoconstituents. TLC profile of hexane extracts of fruits and flowers were developed using anisaldehyde sulphuric acid/ceric sulphate (steroids/terpenoids) and Dragendorff’s spray reagents (alkaloids). Petroleum ether: Chloroform: Methanol (5: 4.5: 0.5) showed good resolution for the hexane extracts of fruit and flower when treated with Dragendorff’s spray reagent. Petroleum ether: Chloroform (1:1) was best for the hexane exacts of flowers and fruits when sprayed with ceric sulphate spray reagent


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