scholarly journals A Notorious Mimicker Nasal Melanoma: A Case Report

2021 ◽  
Vol 1 (1) ◽  
pp. 30-32
Author(s):  
Shankar Bastakoti ◽  
Dej Kumar Gautam ◽  
Suraj Raj Upreti ◽  
Nandita Jha ◽  
Ishan Dhungana
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Malignant Melanoma ◽  
Poor Prognosis ◽  
Incisional Biopsy ◽  
Vascular Neoplasm ◽  
Sinonasal Carcinoma ◽  
Poorly Differentiated ◽  
Age And Sex ◽  
Hmb 45

Melanomas arising in the nasal cavity or paranasal sinus are rare and have a poor prognosis and is more aggressive than cutaneous counter part. The incidence rate reaches its peak when the patients are in the 5th to 8th decades of life, and the disease is slightly more common in males than females; age and sex do not affect the prognosis. We present a case with histologically deceiving features which was proven Malignant Melanoma by application of Immunohistochemistry. On sinoscopic examination, a mass noted of which incisional biopsy was obtained. Histologically, poorly differentiated Sinonasal carcinoma and Malignant Vascular Neoplasm was differential diagnosis. On immunohistochemistry, strong expression of SOX-10, Melan-A, HMB-45 was observed and p63, CK-7, CK20, Synaptophysin, CD56, CD138, CD45, S100, Desmin, Myogenin were all non-immunoreactive. Thus Malignant Melanoma was final diagnosis.Awareness of melanoma mimickers is very important for clinicians in general, and

scholarly journals Primary Colorectal Adenocarcinoma Metastatic to the Breast: Case Report and Review of Nineteen Cases

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Rodney E. Shackelford ◽  
Pushpa Allam-Nandyala ◽  
Marilyn M. Bui ◽  
John V. Kiluk ◽  
Nicole Nicosia Esposito
Keyword(s):  
Colon Cancer ◽  
Case Report ◽  
Malignant Melanoma ◽  
Poor Prognosis ◽  
Colorectal Adenocarcinoma ◽  
Medical Literature ◽  
Rare Event ◽  
Poorly Differentiated ◽  
Disseminated Disease ◽  
Breast Malignancies

Metastases to the breast from extramammary primaries are uncommon and account for 0.5–6% of all breast malignancies (Georgiannos et al., 2001, and Vizcaíno et al., 2001). Malignant melanoma, lymphoma, and lung and gastric carcinomas are the most frequently encountered nonmammary metastases to the breast in adults (Georgiannos et al., 2001, and Chaignaud et al., 1994). Primary colorectal adenocarcinoma (CRC) metastatic to the breast is extremely rare, with the medical literature having only 19 recorded cases. Typically CRC metastatic to the breast is indicative of widely disseminated disease and a poor prognosis. Here we present a case of poorly differentiated colon cancer metastatic to the breast and review the current literature on this rare event.

scholarly journals Recurrent Oral Eosinophilic Ulcers of the Oral Mucosa. A Case Report

2018 ◽  
Vol 12 (1) ◽  
pp. 19-23
Author(s):  
Norberto Sugaya ◽  
Fernanda Martignago ◽  
Decio Pinto ◽  
Dante Migliari
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Autoimmune Disease ◽  
Oral Mucosa ◽  
White Woman ◽  
Recurrent Aphthous Stomatitis ◽  
Incisional Biopsy ◽  
Oral Herpes ◽  
Main Culprit ◽  
Proper Diagnosis

Objective: This article describes a case of an Oral Eosinophilic Ulcer (OEU) in an otherwise healthy 31-year-old white woman. Introduction: The importance of reporting this case was the presence of recurrent episodes with lesions appearing in different areas of the oral mucosa, a type of manifestation not commonly associated with this disease. A typical manifestation of OEU occurs as a single ulceration that goes into healing after an incisional biopsy, a procedure usually required for a proper diagnosis of the disease. In spite of trauma being suggested as the main culprit of OEU, the exact pathogenesis mechanism of this disease remains controversial. Case report: The pattern of the present case contradicts the usually common course of the disease, as the patient had experienced many recurrent episodes for almost 2.5 years, with the recurrences occurring even after biopsies performed during some of the relapses. Differential diagnosis included recurrent aphthous stomatitis, recurrent intra-oral herpes, autoimmune disease, Crohn’s disease and malignancy. Conclusion: Fortunately, the patient has been free of any recurrences for 1.5 years since the last biopsy was taken at the time she came to our clinic seeking treatment.

Squamous Cell Carcinoma of the Penis with Pulmonary Metastasis and Paraneoplastic Hypertrophic Osteopathy in a Dog

2017 ◽  
Vol 53 (5) ◽  
pp. 277-280
Author(s):  
Victoria Jenkins ◽  
Carlos Henrique de Mello Souza ◽  
Louis-Phillippe de Lorimier ◽  
Evandro de Toledo-Piza
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Complete Resolution ◽  
Poor Prognosis ◽  
Palliative Treatment ◽  
Clinical Signs ◽  
Incisional Biopsy ◽  
Intact Male

ABSTRACT Squamous cell carcinoma of the penis was diagnosed by incisional biopsy of a penile mass in a 12 yr old intact male beagle dog presenting with hemorrhagic discharge from the prepuce. Penile amputation, orchiectomy with scrotal ablation, and scrotal urethrostomy were performed. Hypertrophic osteopathy secondary to pulmonary metastatic disease occurred 10 mo after the surgery. Palliative treatment with piroxicam was administered and led to complete resolution of the clinical signs of the pain. Sixteen months following surgery, the dog presented with significant dyspnea and anorexia and was euthanized due to poor prognosis. This case report describes a rare penile tumor, squamous cell carcinoma. Consequent paraneoplastic hypertrophic osteopathy and its palliative treatment are also reviewed.

Aggressive Pregnancy Tumor Mimicking A Malignant Neoplasm: A Case Report

2009 ◽  
Vol 10 (6) ◽  
pp. 72-78 ◽  
Author(s):  
Khansa Ababneh ◽  
Taiseer Al-Khateeb
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Alveolar Bone ◽  
Malignant Neoplasm ◽  
Pyogenic Granuloma ◽  
Alveolar Bone Loss ◽  
Incisional Biopsy ◽  
Spontaneous Bleeding ◽  
Important Differential Diagnosis ◽  
Soft Tissue Masses

Abstract Aim The aim of this report is to present the management of an aggressive, highly proliferative pregnancy tumor with clinical and radiographic characteristics highly suggestive of a malignant neoplasm. Background Pregnancy tumor is a benign hyperplastic gingival lesion occurring during pregnancy that is indistinguishable from a pyogenic granuloma arising in nonpregnant females, or in males. The lesion usually grows over a few months and tends to bleed. Case Description A 28-year-old woman at four months of gestation was referred for a massive gingival swelling (5.5 cm in greatest diameter) on the mandibular left side. The lesion was painful and continued to grow very rapidly over a threeweek period, with spontaneous bleeding, and it interfered with speech and mastication. Advanced alveolar bone loss also was found beneath the lesion. A malignant process was suspected, and an incisional biopsy revealed a pregnancy tumor. The lesion was excised under general anesthesia during the pregnancy with no untoward reactions. Summary Pregnancy tumor represents an important differential diagnosis of oral masses and can behave in a very aggressive fashion, mimicking a malignant tumor. Clinical Significance This lesion should always be included in the differential diagnosis of soft tissue masses in a pregnant woman even if the lesion is clinically very aggressive. It is acceptable practice to excise aggressive variants of this lesion during pregnancy to avoid distressing side effects. Citation Ababneh K, Al-Khateeb T. Aggressive Pregnancy Tumor Mimicking a Malignant Neoplasm: A Case Report. J Contemp Dent Pract [Internet]. 2009 Nov; 10(6):072-078. Available from: http://www.thejcdp.com/journal/view/ volume10-issue6-ababneh.

scholarly journals Malignant melanoma of the bladder: A case report

2014 ◽  
Vol 8 (1-2) ◽  
pp. 54 ◽  
Author(s):  
Hamide Sayar ◽  
Seyda Erdogan ◽  
Fulya Adamhasan ◽  
Esma Gurbuz ◽  
Mehmet Fatih İnci
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Immunohistochemical Staining ◽  
Correct Diagnosis ◽  
Primary Lesion ◽  
Histological Features ◽  
Malignant Melanomas ◽  
Metastatic Lesions ◽  
S 100 ◽  
Hmb 45

Primary malignant melanoma of the bladder is very rare. Rather than being a primary lesion, malignant melanomas of the bladder are more commonly metastatic lesions. The histopathological appearance largely does not differ from that of melanoma at other body sites. It is often difficult to discriminate whether a bladder melanoma is primary or metastatic. Therefore, a careful review of histological features and performing necessary immunohistochemical staining procedures for S-100 protein and HMB-45 are very important in achieving a correct diagnosis. We report a case of hypomelanotic malignant melanoma of the bladder. Despite the variety of therapies available for primary melanomas of the bladder, the prognosis is still poor.

scholarly journals Coexisting Malignant Melanoma and Blue Nevus of the Uterine Cervix: An Unusual Combination

2012 ◽  
Vol 2012 ◽  
pp. 1-7
Author(s):  
David Parada ◽  
Karla B. Peña ◽  
Frances Riu
Keyword(s):  
Differential Diagnosis ◽  
Postmenopausal Woman ◽  
Malignant Melanoma ◽  
Uterine Cervix ◽  
Poor Prognosis ◽  
Vaginal Bleeding ◽  
Blue Nevus ◽  
Unusual Combination ◽  
Abnormal Vaginal Bleeding ◽  
Immunohistochemical Studies

Malignant melanoma (MM) and blue nevi of the uterine cervix are an extremely rare neoplasm, probably derived from embryologic migration of melanocytes from the neural crest. MM displays aggressive behavior with a poor prognosis. We report the case of a 76-year-old postmenopausal woman abnormal vaginal bleeding. She underwent a hysterectomy and bilateral salpingo-oophorectomy with paraaortic-iliac lymphadenectomy. Histopathological and immunohistochemical studies were consistent with the diagnosis of MM and blue nevi in the uterine cervix. Although it is extremely rare, this case suggests that MM of the uterine cervix should be considered in the differential diagnosis of undifferentiated neoplasm. Early diagnosis is essential in order to warrant a better prognosis, although there are no cases of cure described.

Macroglossia combined with lymphangioma: a case report

2004 ◽  
Vol 27 (2) ◽  
pp. 167-169 ◽  
Author(s):  
Marcio Guelmann ◽  
Joseph Katz
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Dental Care ◽  
Clinical Presentation ◽  
Traumatic Injury ◽  
Diagnosis And Treatment ◽  
White Female ◽  
Severe Bleeding ◽  
Incisional Biopsy ◽  
Review Of The Literature

A four year old white female with a clinical presentation of macroglossia is described. Speech disturbances and occasional episodes of traumatic injury to the tongue with severe bleeding brought the patient to seek dental care. Lymphangioma was diagnosed after incisional biopsy. The differential diagnosis of tongue enlargement in children is discussed including review of the literature relevant to the diagnosis and treatment of lymphangioma.

scholarly journals Metastatic Jaw Swelling as the Manifestation of Leiomyosarcoma of Uterus- A Case Report

1970 ◽  
Vol 29 (2) ◽  
pp. 96-98
Author(s):  
MM Hassan ◽  
M Ahmed ◽  
RA Bhuiyan ◽  
MM Rahman ◽  
ME Mahmud
Keyword(s):  
Case Report ◽  
Poor Prognosis ◽  
Hard Palate ◽  
Soft Tissues ◽  
Palliative Chemotherapy ◽  
Metastatic Tumor ◽  
Incisional Biopsy ◽  
The Right ◽  
Molar Region ◽  
Oral Metastasis

Metastatic tumor in oral region is uncommon and may occur in the oral soft tissues or in the Jaw bone. Because of their rarity, metastasis in oral cavity are challenging to diagnose and treat. Oral metastasis is associated with poor prognosis. This case report is of a 45 year old female with a small pedunculated swelling on the left side of the hard palate in the molar region for 30 days. Incisional biopsy revealed metastatic leiomyosarcoma with possible primaries in the uterus. Metastasis in the right lung and liver was also diagnosed. Palliative chemotherapy was started but the patient died after two weeks of diagnosis after receiving the first cycle of chemotherapy. DOI: http://dx.doi.org/10.3329/jbcps.v29i2.7954 (J Bangladesh Coll Phys Surg 2011; 29: 96-98)

scholarly journals Atypical Carcinoid Neuroendocrine Tumor of the Ureter: A Case Report and Literature Review

2018 ◽  
Vol 04 (04) ◽  
pp. e171-e175 ◽  
Author(s):  
Huay Yuen ◽  
Gerald Rix ◽  
Soumadri Sen ◽  
Venkata Kusuma
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Neuroendocrine Tumor ◽  
Neuroendocrine Tumors ◽  
Poor Prognosis ◽  
Postoperative Outcome ◽  
Postoperative Outcomes ◽  
Atypical Carcinoid ◽  
Poorly Differentiated

AbstractNeuroendocrine tumors (NETs) of the ureter are rare, with less than 40 cases described in the literature. A majority of tumors described are poorly differentiated tumors with a poor prognosis. We present the case of a moderately differentiated atypical carcinoid NET of the ureter with a good postoperative outcome. A literature review was also performed to identify similar cases to compare their management and postoperative outcomes.

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