scholarly journals Medical care contact for infertility and related medication use during pregnancy – a European, cross-sectional web-based study

2021 ◽  
Vol 29 (1-2) ◽  
Author(s):  
Miljana Ilic ◽  
Hedvig Nordeng ◽  
Angela Lupattelli

Aims: The aim of the study was two-fold: i) to determine the prevalence of medical care contact for infertility in European countries; ii) to map overall and long-term/chronic medication use during pregnancy in women who sought medical care due to infertility.Methods: This is a sub-study of the Multinational Medication Use in Pregnancy Study, a cross-sectional, web-based study conducted from October 2011 to February 2012. We included 8097 participants from Europe who were pregnant or new mothers. We collected data on overall and long-term/chronic medication use, medical care seeking due to infertility, and whether women eventually conceived spontaneously or with the aid of infertility treatment.Results: Medical care contact for infertility was lower in Western Europe (prevalence estimate: 10.0-15.3%), compared with Northern (15.2-17.5%) or Eastern (17.4-20.9%), but Poland had the lowest estimate (8.0%). Overall, 660 (8.2%) women sought medical care due to infertility but conceived spontaneously; 548 (6.8%) conceived aided by fertility treatment, and 6889 (85.0%) women did not seek help. Use of any medication was comparable across the three groups (range 80.4-82.5%), but women seeking help for infertility (21.8-24.6%) took more often long-term/chronic medications than women who did not (14.8%).Conclusion: Medical care contacts for infertility varies greatly across European countries. Women who had medical contact due to infertility used more often chronic medications in pregnancy than women who did not, pointing to more co-morbidities and risk pregnancies.

BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e014934 ◽  
Author(s):  
Bich Thuy Truong ◽  
Angela Lupattelli ◽  
Petter Kristensen ◽  
Hedvig Nordeng

Background and objectiveA comparison of sick leave in pregnancy between countries is difficult as most studies have been conducted in single countries in Scandinavia. The objective of this study was to explore patterns of and reasons for sick leave during pregnancy on a multinational level, focusing on medication use but also differences in sick leave policies.Design and settingCross-sectional, web-based study in 12 European countries from October 2011 to February 2012. Data were collected via an electronic questionnaire.ParticipantsPregnant women and mothers of children under the age of 1 year.Primary outcome measureSick leave prevalence in pregnancy.ResultsOf 6686 women included, 3385 (50.6%) had been on sick leave during pregnancy. The rates of sick leave varied across countries, ranging from 31.7%–34.8% in Sweden and the UK to 62.4%–71.3% in Norway, Serbia, Croatia and Poland. The most common reasons for being on sick leave were pregnancy complications (26.5%); pain in the neck, back or pelvic girdle (16.2%); and nausea and vomiting (NVP, 16.0%). Women using medications for acute illnesses were more likely to be on sick leave than their non-medicated counterparts, while an opposite trend was observed for women with chronic disorders, where non-medicated women were more likely to be on sick leave. Women from countries with ‘low’ sick leave policies were less likely to have extensions of sick leaves compared with women from countries with ‘medium’ policies (adjusted OR 0.63, 95% CI 0.49 to 0.82).ConclusionThe rates of sick leave in pregnancy vary greatly across European countries. Women using medications were more likely to be on sick leave, especially for acute illnesses. The differences in sick leave patterns across countries only partially reflected differences in sick leave policies, which implies that sick leave in pregnancy is also affected by other national differences.


Author(s):  
Angela Lupattelli ◽  
Marta Picinardi ◽  
Anna Cantarutti ◽  
Hedvig Nordeng

Nation-wide information about medication use in pregnancy is lacking for Italy, and no study has so far investigated the prescribed medications which pregnant women deliberately avoid. In this study, we map medication use patterns in pregnancy, as well as the extent and type of prescribed medications which are purposely avoided by pregnant women in Italy. This is a sub-study within the “Multinational Medication Use in Pregnancy Study”—a cross-sectional, web-based study conducted in Italy from 7 November 2011 to 7 January 2012. Using an anonymous electronic questionnaire, we collected data from pregnant women and new mothers on medication use and deliberate avoidance during pregnancy and maternal characteristics. The sample included 926 women residing in Italy. The point prevalence of total medication use was 71.2%. Whereas 61.4% and 12.4% of women reported medication use for the treatment of short and longer-term illnesses, respectively, only 8.8% reported medication use for the treatment of both a short and a longer-term illness in pregnancy. We found no substantial differences in estimates across various geographical areas of Italy. Overall, 26.6% of women reported to have deliberately avoided a prescribed medication in pregnancy—most often nimesulide or ketoprofen, but also antibiotics. We conclude that prenatal exposure to medication is common among women in Italy, but estimates are lower than in other Western countries. Intentional avoidance of important medications by pregnant women raises concerns about the safeguarding of maternal–child health.


BMJ Open ◽  
2014 ◽  
Vol 4 (2) ◽  
pp. e004365 ◽  
Author(s):  
A Lupattelli ◽  
O Spigset ◽  
M J Twigg ◽  
K Zagorodnikova ◽  
A C Mårdby ◽  
...  

2017 ◽  
Vol 32 (4) ◽  
pp. 775-785 ◽  
Author(s):  
Kristel Paque ◽  
Monique Elseviers ◽  
Robert Vander Stichele ◽  
Koen Pardon ◽  
Marianne J Hjermstad ◽  
...  

Background: Information on medication use in the last months of life is limited. Aim: To describe which medications are prescribed and deprescribed in advanced cancer patients receiving palliative care in relation to time before death and to explore associations with demographic variables. Design: Prospective study, using case report forms for monthly data collection. Medication included cancer treatment and 19 therapeutic groups, grouped into four categories for: (1) cancer therapy, (2) specific cancer-related symptom relief, (3) other symptom relief and (4) long-term prevention. Data were analysed retrospectively using death as the index date. We compared medication use at 5, 4, 3, 2 and 1 month(s) before death by constructing five cross-sectional subsamples with medication use during that month. Paired analyses were done on a subsample of patients with at least two assessments before death. Setting/participants: We studied the medication use of 720 patients (mean age 67, 56% male) in 30 cancer centres representing 12 countries. Results: From 5 to 1 month(s) before death, cancer therapy decreased (55%–24%), most medications for symptom relief increased, for example, opioids (62%–81%) and sedatives (35%–46%), but medication for long-term prevention decreased (38%–27%). The prevalence of chemotherapy was 15.5% in the last month of life, with 9% of new courses started in the last 2 months. With higher age, chemotherapy and opioid use decreased. Conclusion: Medications for symptom relief increased in almost all medication groups. Deprescribing was found in heart medication/anti-hypertensives and cancer therapy, although use of the latter remained relatively high.


2020 ◽  
Vol 15 ◽  
Author(s):  
Esra’ Taybeh ◽  
Rawan Kokash ◽  
Ahmad Talhouni ◽  
Mervat Alsous

Background: Knowledge of medication use during pregnancy presents a concern to pharmacists upon graduation since they will be responsible for drug related inquiries and counselling pregnant women about their medications. The present study aimed to assess undergraduate senior pharmacy students’ knowledge about medication use during pregnancy in Jordan. Methods: A cross-sectional survey was conducted in Jordanian universities. A total of 409 senior pharmacy students participated in the study. Results: The results found that the majority of the students (60.6%) did not have enough instruction on medications during pregnancy through their undergraduate study. Overall, only 2.5% of the participating students were considered to have good knowledge about medicine use during pregnancy and accordingly the majority (52.6%) were not confident to recommend medicines for pregnant women in the future. In view of that, participating students suggested the addition of an obligatory course to the current curriculum. Students in public universities, Pharm.D. students, and those in their sixth year of study were more knowledgeable than others (P > 0.05). Conclusion: It was concluded that pharmacy students have low knowledge regarding medication use in pregnancy. The results call for a reassessment of the current pharmacy curriculum.


2017 ◽  
Vol 81 (1) ◽  
pp. 42-50 ◽  
Author(s):  
Helen Lynch ◽  
Maria Prellwitz ◽  
Christina Schulze ◽  
Alice H Moore

Introduction Play is viewed as an important occupation in childhood and consequently in children's occupational therapy. However, few studies have explored the place of play in therapy practice. This study aimed to contribute to this knowledge gap by exploring play in occupational therapy in three European countries. Method A cross-sectional survey of occupational therapists in Ireland, Sweden and Switzerland was conducted to examine the use of play with children under 12 years old. A web-based survey was distributed to 935 occupational therapists, resulting in 338 returned surveys (36%). Responses were analysed using descriptive statistics and content analysis. Results Results were organised into three themes: (1) demographics and practice context; (2) play education and (3) use of play in practice. Respondents reported that although they valued play as an occupation, their primary focus was on play as a means to achieving other goals. Lack of education on play (research, theory and interventions) and pressures in the workplace were identified as barriers to play-centred practice. Conclusion Findings indicate that there is a mismatch between therapists valuing play as an occupation and how play is utilised in therapy practice. There is a need to strengthen education and research on play occupation to strengthen play-centred practice.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Ilonka Kreitschmann-Andermahr ◽  
Sonja Siegel ◽  
Christa Gammel ◽  
Karen Campbell ◽  
Leslie Edwin ◽  
...  

Background. Cushing’s disease (CD) and Cushing’s syndrome (CS) are chronic illnesses, characterized by symptoms of prolonged hypercortisolism, which often changes to hypocortisolism after successful treatment. In view of the high disease burden of CD/CS patients and long-term impaired quality of life, the present survey was conducted to gain information about subjective illness distress and patients’ specific needs in terms of supportive measures beyond medical interventions. Patients and Methods. Cross-sectional questionnaire study including patients with CD treated in 2 German neurosurgical tertiary referral centers and CD/CS patient members of a US-based patient support group completed a survey inquiring about disease burden, coping strategies, and support needs. Additionally, the degree of interest in different offers, e.g., internet-based programs and seminars, was assessed. Results. 84 US and 71 German patients answered the questionnaire. Patients in both countries indicated to suffer from Cushing-related symptoms, reduced performance, and psychological problems. 48.8% US patients and 44.4% German patients stated that good medical care and competent doctors helped them the most in coping with the illness. US patients were more interested in support groups (p=0.035) and in courses on illness coping (p=0.008) than the German patients, who stated to prefer brochures (p=0.001). 89.3% of US patients would attend internet-based programs compared to 75.4% of German patients (p=0.040). There were no differences between groups for the preferred duration of and the willingness to pay for such a program, but US patients would travel longer distances to attend a support meeting (p=0.027). Conclusion. Patients in both countries need skilled physicians and long-term medical care in dealing with the effects of CD/CS, whereas other support needs differ between patients of both countries. The latter implies that not only disease-specific but also culture-specific training programs would need to be considered to satisfy the needs of patients in different countries.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
F Griffin ◽  
M Heelan ◽  
M Kumar

Abstract Introduction Protecting the wellbeing of staff in the NHS is becoming ever more critical as we progress through this pandemic. We sought to identify the impact of the pandemic and changes in working pattern on wellbeing of doctors in training in a teaching hospital. Method Cross sectional study, with primary data collection using a web-based survey. Questionnaire was designed to identify issues relating to the personal wellbeing before and since the onset of the pandemic (Nov 2019-Feb 2020 vs March 2020- June 2020). Trainees in all surgical specialities were invited to participate. Results Thirty-six doctors responded. Across the timepoints there was a marked increase in reports of the following: constant fatigue (+500%), headaches (250%), loss of motivation (+500%), loss of interest in hobbies/friends (+566%), anger (+500%), loss of focus (+320%) and heightened emotional state (+700%). Almost 70% reported difficulty sleeping in the preceding month, with only 50% feeling they received adequate rest between shifts. Feelings of ‘too tired to drive’ increased by 216% with accidents or near misses increasing by 500%. Use of alcohol as coping mechanism increased by 500%, and comfort eating rose by 244%. 50% considered leaving their post. Conclusions These findings are significant and point to a dangerous trend if left unchecked. The causes of these outcomes are multi-factorial; changes to working patterns, cancellation of leave, redeployment, and anxieties around career progression were noted. The long-term health implications on the workforce should not be overlooked. This requires a collective response and action by employers, training and regulatory bodies and government.


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