GH Deficiency in a Dalmatian Puppy with Megaesophagus

2013 ◽  
Vol 49 (6) ◽  
pp. 407-411 ◽  
Author(s):  
Kyu-Deok Cho ◽  
Ji-Houn Kang ◽  
Sung-Jun Noh ◽  
Dongwoo Chang ◽  
Ki-Jeong Na ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Physical Examination ◽  
Growth Retardation ◽  
Gh Deficiency ◽  
Clinical Manifestations ◽  
Pituitary Dwarfism

An 8 wk old female Dalmatian weighing .56 kg presented with growth retardation. The puppy exhibited no abnormalities during physical examination other than significantly reduced growth compared with her littermates. Endocrine results suggested pituitary dwarfism. Two wk later, the puppy returned due to the onset of megaesophagus, but the puppy unfortunately died the following morning. This case report describes the diagnosis of dwarfism in a Dalmatian puppy that was caused by growth hormone (GH) deficiency and describes its early clinical manifestations.

scholarly journals Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Franco Ferrante ◽  
Sergio Blasi ◽  
Rolando Crippa ◽  
Francesca Angiero
Keyword(s):  
Growth Hormone ◽  
Surgical Intervention ◽  
Trauma Surgery ◽  
Clinical Manifestations ◽  
Review Of The Literature ◽  
Dental Anomalies ◽  
Prosthetic Rehabilitation ◽  
Pituitary Dwarfism ◽  
Dental Abnormalities ◽  
Destructive Processes

Hypopituitarism is a disorder caused by a reduced level of trophic hormones that may be consequent on different destructive processes. The clinical manifestations depend on the type of hormone involved. A deficiency of growth hormone (GH) in children causes the lack of growth known as pituitary dwarfism. The case is reported of a patient with pituitary dwarfism, multiple dental anomalies, functional prosthetic problems, and a revision of the literature. She was subjected to prosthetic rehabilitation without surgical intervention, using zirconium substructures, thus eliminating the potential complications that may require trauma surgery. The therapeutic approach adopted led to excellent results and restored an aesthetic smile.

scholarly journals A case of urticaria multiforme with unusual presentation

2019 ◽  
Vol 6 (6) ◽  
pp. 1946
Author(s):  
Mohammad S. Alkhowailed
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Erythema Multiforme ◽  
Case History ◽  
Diagnostic Tests ◽  
Clinical Manifestations ◽  
Unusual Presentation ◽  
Effective Management ◽  
Urticarial Vasculitis ◽  
Wide Range

Urticaria multiforme is a condition which manifests as acute, polycyclic, annular oedematous pink plaques with an ecchymosis hue that is associated with acral edema. The condition is often misdiagnosed as erythema multiforme, serum-sickness-like reactions, or urticarial vasculitis. Author present a case of acute annular urticaria in a 3-year-old girl who presented with unusual clinical manifestations of the condition. Through this case report, Author aim to emphasize the wide range of morphologic manifestations that can be seen in urticaria multiforme. This can assist pediatric physicians to differentiate urticaria multiforme from other clinical dermatologic conditions and prevent misdiagnosis. A detailed case history and physical examination, along with relevant diagnostic tests can enable prompt and effective management of the condition.

Growth retardation in hypothyroidism and growth hormone deficieny : A case report

2021 ◽  
Author(s):  
Rihab Laamouri ◽  
Imen Rojbi ◽  
Chayma Besrour ◽  
Marwa Majdoub ◽  
Youssef Lakhoua ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Growth Retardation

Vascular Malformation of Hypothalamus: A Cause of Isolated Growth Hormone Deficiency

PEDIATRICS ◽  
1980 ◽  
Vol 66 (2) ◽  
pp. 306-309
Author(s):  
J. D. Russell ◽  
P. H. Wise ◽  
H. G. Rischbieth
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Birth Weight ◽  
Vascular Malformation ◽  
Adelaide Hospital ◽  
Birth Trauma ◽  
Hormone Deficiency ◽  
Royal Adelaide Hospital ◽  
Pituitary Dwarfism ◽  
History Of

The etiology of pituitary dwarfism is varied.1 The majority of cases are idiopathic (with an observed increase in history of birth trauma), and approximately one third are associated with radiologic changes of craniopharyngioma or pituitary tumor. A number are associated with midline embryonal defects, histiocytosis, basilar meningitis, and sarcoidosis. An increasingly reported cause is craniospinal irradiation for oncologic disease. An unusual, and previously unreported, cause is described. CASE REPORT A male child, born Aug 8, 1961, was investigated at the Royal Adelaide Hospital for shortness of stature. He was the second of four siblings; gestation and delivery were normal with a birth weight of 2.6 kg.

Development of antibodies against growth hormone (GH) during rhGH therapy in a girl with idiopathic GH deficiency: a case report

2013 ◽  
Vol 26 (7-8) ◽  
Author(s):  
Cristina Meazza ◽  
Michael Schaab ◽  
Sara Pagani ◽  
Valeria Calcaterra ◽  
Elena Bozzola ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Gh Deficiency ◽  
Rhgh Therapy

scholarly journals Leprosy Mimicking as Rheumatoid Arthritis: A Case Report

2021 ◽  
Vol 9 (C) ◽  
pp. 277-279
Author(s):  
Made Edwin Sridana ◽  
Pande Ketut Kurniari ◽  
Gede Kambayana
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Physical Examination ◽  
Peripheral Nerves ◽  
Clinical Manifestations ◽  
Mycobacterium Leprae ◽  
History Taking ◽  
Blood Tests ◽  
The Face ◽  
Bilateral Distribution

Leprosy is a chronic granulomatous infection caused by Mycobacterium leprae, which mainly damages the skin and peripheral nerves, and can also infect joints and bones. Clinical manifestations are complex, varied, and often underdiagnosed. The clinical manifestations vary and are called "the great imitator". musculoskeletal features are common in leprosy but infrequently reported. A case of borderline lepromatous (BL) type leprosy was initially suspected as rheumatoid arthritis in a 20-year-old Balinese male who complained of pain and swelling in small joints, accompanied by lesions in the form of multiple erythema macules, round-shaped geography, indistinct boundaries, with bilateral distribution is almost symmetrical in the face, thoracoabdominal, and extremity regions. The diagnosis of BL type leprosy is based on history taking, physical examination, and investigations in the form of Ziehl-Neelsen stain and blood tests.

Microdeletion in the IGF-1 receptor gene of a patient with short stature and obesity: a case report

2021 ◽  
Vol 34 (2) ◽  
pp. 255-259
Author(s):  
Jong Seo Yoon ◽  
Il Tae Hwang
Keyword(s):  
Growth Hormone ◽  
Short Stature ◽  
Growth Retardation ◽  
Receptor Gene ◽  
Recombinant Human Growth Hormone ◽  
Elevated Serum ◽  
Clinical Manifestations ◽  
Postnatal Growth ◽  
Hormone Deficiency ◽  
Rhgh Treatment

Abstract Objectives Defects in the IGF-1 receptor gene (IGF1R) induce IGF-1 resistance, characterized by intrauterine and postnatal growth retardation, normal or elevated serum IGF-1 levels, and feeding problems. Obesity, idiopathic growth hormone deficiency (IGHD), bone age advancement, and serum IGF-1 level in the lower half of the reference range are very rare clinical features in patients with IGF1R defects. Case presentation In this study, we report the atypical clinical manifestations of IGF1R defects. Short stature girl born small for gestational age were initially diagnosed with IGHD. No catch-up growth was achieved despite sufficiently elevated IGF-1 levels after recombinant human growth hormone (rhGH) treatment. Single nucleotide polymorphism microarray analysis finally confirmed terminal deletion of 15q26.2q26.3 in the subject. Conclusion Intrauterine growth retardation, postnatal growth failure, and IGF-1 resistance during rhGH treatment are homologous features exhibited by affected patients, and may be predictive of IGF1R defects.

scholarly journals HIPERTIROIDISMEE GRAVES DISEASE:CASE REPORT

2020 ◽  
Vol 6 (1) ◽  
pp. 30-35
Author(s):  
Putri Rahayu Srikandi
Keyword(s):  
Case Report ◽  
Thyroid Hormone ◽  
Thyroid Gland ◽  
Physical Examination ◽  
Clinical Condition ◽  
Laboratory Tests ◽  
Clinical Manifestations ◽  
Antithyroid Drugs ◽  
Graves Disease ◽  
Thyroid Hormone Levels

AbstractAbstrak:Hipertiroid adalah kondisi klinis yang disebabkan peningkatan sintesis dan sekresi hormone oleh kelenjar tiroid, sedangkan tirotoksikosis mengacu pada manifestasi klinis.  Penyakit graves merupakan penyebab hipertiroid yang paling sering ditemukan sekitar 60-80% dari semua kasus tirotoksikosis di seluruh dunia. Pada laporan kasus ini akan dibahas pasien Ny. NMS berusia 56 tahun datang dengan keluhan dada berdebar-debar yang dirasakan sejak 3 minggu yang lalu dan pada pemeriksaan fisik didapatkan adanya pembesaran kelenjar tiroid dan indeks Wayne pada kasus ini didapatkan  21. Pada pemeriksaan laboratorium didapatkan kadar Tyroid Stimulating Hormone (TSH) 0,005 uIU/ml, , dan free Tiroksin (fT4) 7,77mg/dl. Penatalaksanaan pada kasus ini yaitu pasien diberikan tyrozol  3x10 mg sehari dan propanolol 3x10mg. Kata kunci: graves, hipertiroidism, tirotoksikosis AbstractHipertiroidisme is a clinical condition caused by increased synthesis and secretion of hormones by the thyroid gland. Thyrotoxicosis is defined as clinical manifestations related to increased thyroid hormone levels. Graves' disease (GD) persists as the most frequently encountered etiology of hipertiroidisme causing approximately 60-80% of all cases of thyrotoxicosis worldwide. In this case report we will discuss woman patient Mrs.NMS aged 56 years with complaints of palpitations felt since three weeks ago and physical examination found enlargement of the thyroid gland and Wayne index in this case obtained 21. In laboratory tests found levels of TSH 0.005 uIU/ml and T4 7.77 mg/dl. Principle in the treatment of hipertiroidisme is suppressing the production of thyroid hormone by using antithyroid drugs. Management in this case that the patient is given 3x10 mg Thyrozol and propranolol 3x10 mg. Keywords: graves, hipertiroidisme, thyrotoxicosis

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