Frequency of Dry Eye in Glaucoma Patients Using Topical Anti-Glaucoma Therapy

2021 ◽  
Vol 15 (10) ◽  
pp. 2606-2608
Author(s):  
Nesr Farooq ◽  
Hafiz Waqar Ahmad Ghauri ◽  
Asad Zaman Khan ◽  
Abdul Bari Kakar ◽  
Muhammad Amin ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Observational Study ◽  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Glaucoma Medication ◽  
Glaucoma Therapy ◽  
Department Of Ophthalmology ◽  
Time Test ◽  
Break Up

Aim: To determine the prevalence of dry eye in glaucoma patients using topical anti-glaucoma therapy. Study Design: Descriptive observational study Place and duration of study: Department of Ophthalmology, Shalimar Medical & Dental College Lahore from 1st November 2020 to 30th April 2021. Methodology: Ninety patients of both genders were enrolled. Detailed demographics of enrolled cases age, sex and body mass index were recorded after taking informed written consent. Patients using topical anti-glaucoma therapy for more than 8 months and having symptoms of stinging and burning sensations itching, watering, irritation, due to regular use of topical antiglaucoma drugs were presented. Basal Schrimer’s test and tear film break-up time test was used to measure the frequency of dry eye syndrome as mild, moderate and severe. Results: There were 60 (66.7%) females and 30 (33.3%) patients were males. Mean age of the patients were 45.61±7.66 years with mean BMI 26.24±8.71 kg/m2. We found that 40 (44.4%) patients had burning and stinging sensations, itching found in 21 (23.3%), dry eye sensations were found in 16 (17.8%) patients and watering and irritation found in 13 (14.4%) .According to tear film break-up time test 20 (22.2%) cases did not show dry eye syndrome and 19 (21.1%) patients were normal in Basal Schrimer’s test. Conclusion: Use of topical anti-glaucoma medication resulted in dry eye syndrome as well as a decrease in the tear film's stability. Keywords: Anti-glaucoma therapy, Basal Schrimer`s test, Tear film break-up time, Anti-glaucoma therapy, Dry eye syndrome

scholarly journals Dry Eye Syndrome in Glaucomatous Patients using Topical Anti-Glaucoma Therapy

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Nabila Zulfiqar ◽  
Muhammad Sufyan Aneeq Ansari ◽  
Khurram Nafees ◽  
Rabia Nawaz ◽  
Manzra Shaheen
Keyword(s):  
Observational Study ◽  
Study Design ◽  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Film Stability ◽  
Glaucoma Therapy ◽  
Tear Film Stability ◽  
Time Test ◽  
Break Up

Purpose:  To determine the frequency of Dry eye in Glaucoma patients using topical anti-glaucoma therapy. Study Design:  Descriptive Observational study. Place and Duration of Study:  Study was conducted in outpatient department of Fatima Memorial Hospital Shadman, Lahore, from October 2016 to February 2017. Material & Methods:  In this study, 61 diagnosed cases of glaucoma were included. Patients with significant dermatological problems that may be associated with dry eye such as rosacea and blepharitis were excluded from the study. The individuals were assessed by consultant Ophthalmologist for Dry eye syndrome having symptoms of stinging and burning sensations itching, watering, irritation, due to regular use of topical anti-glaucoma drugs. A written consent was taken from every patient before the test. The ocular surfaces of the patients were evaluated using Tear film break-up time test and Basal Schrimer’s test. Patients having TBUT less than 11 seconds were categorized as having dry eye. The degree of dryness was categorized as mild, moderate and sever Dry eye. Results:  Among 61 patients of glaucoma using topical anti-glaucoma therapy, 22 (36.1%) were male and 39 (63.9%) were female. Mean age of the patients was 50.76 ± 15.67 years. On the basis of Tear film Break-up time test, 49 (81%) patients had Tear Break-up time less than 10 seconds and 12 (19%) patients were normal. On the basis of Schrimer`s test 51 (83.66%) patients had Dry eye. Conclusion:  Topical use of anti-glaucoma therapy affects tear film stability and its functions leading to Dry eye syndrome.

scholarly journals PENGARUH EMISI DEBU SEMEN TERHADAP STATUS TEAR FILM MASYARAKAT DI SEKITAR PABRIK PT. SEMEN PADANG

2018 ◽  
Vol 6 (3) ◽  
pp. 654
Author(s):  
Muhammad Syauqie ◽  
Ardizal Rahman ◽  
Getry Sukmawati
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Cross Sectional Study ◽  
Dry Eye Syndrome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Break Up

Permukaan okular rentan terhadap efek iritatif dari debu semen tersebut karena epitel konyungtiva dan kornea hanya dilapisi oleh lapisan tipis tear film. Paparan debu semen jangka panjang menyebabkan terjadinya inflamasi subklinis kronik yang dapat mempengaruhi transdiferensiasi epitel konyungtiva dan densitas sel goblet yang kemudian dapat menyebabkan timbulnya gejala dry eye syndrome. Tujuan penelitian ini adalah menilai status tear film pada masyarakat  yang  terpapar  emisi  debu  semen  dibandingkan  dengan  masyarakat  yang  tidak  terpapar.  Penelitian ini berupa analytic cross sectional study pada dua populasi yaitu kelompok terpapar dan tidak terpapar emisi debu pabrik semen. Semua sampel penelitian dari dua populasi menjalani pemeriksaan pH tear film, Schirmer, Ferning dan Tear Break Up Time (TBUT). Hasil studi mendapatkan peningkatan nilai pH tear film yang bermakna pada penduduk di kelompok terpapar dengan p=0.001. Terdapat juga penurunan kualitas Ferning yang bermakna pada penduduk di kelompok terpapar yang didominasi tipe III dengan p=0.005 dan 0.029. Sedangkan hasil pemeriksaan Schirmer dan TBUT masih dalam batas normal dan tidak terdapat perbedaan yang bermakna antara kedua kelompok. Simpulan studi ini ialah erdapat peningkatan rerata nilai pH tear film dan penurunan kualitas lapisan musin tear film yang bermakna pada masyarakat yang terpapar emisi debu semen namun tidak didapatkan peningkatan kejadian dry eye yang bermakna.

scholarly journals DRY EYE SYNDROME

2009 ◽  
Vol 16 (01) ◽  
pp. 145-148
Author(s):  
TAHIR MUMTAZ MALIK ◽  
SYED ABID HASSAN NAQVI ◽  
MUHAMMAD SHAHID
Keyword(s):  
Study Design ◽  
Dry Eye ◽  
Rose Bengal ◽  
Tear Film ◽  
Descriptive Study ◽  
Dry Eye Syndrome ◽  
Adult Patients ◽  
Military Hospital ◽  
Break Up ◽  
Eye Clinic

Objective: To determine the frequency of dry eye syndrome in adult patients. Study Design: A descriptive study. Setting:Eye Department Military Hospital Rawalpindi. Period: From June 2004 to December 2004. Patients and methods: A total of hundredpatients were randomly selected from the daily OPD at eye department, MH Rawalpindi. They were tested for the presence of dry eyesyndrome by Rose Bengal staining, Schirmer tear strip measurements and Tear film break up time. Results: A total of 67 males and 33females were recruited. Out of these 10 males and 6 females were found to be having dry eye syndrome. Mean patient age was34.3±1.3years (range 20-60 years). Conclusion: The frequency of dry eye syndrome in adult patients attending the eye clinic of MilitaryHospital Rawalpindi is 16%.

scholarly journals PENGARUH EMISI DEBU SEMEN TERHADAP PERMUKAAN OKULAR PADA MASYARAKAT DI SEKITAR PABRIK PT. SEMEN PADANG

2020 ◽  
Vol 43 (2) ◽  
pp. 112
Author(s):  
Muhammad Syauqie
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Cross Sectional Study ◽  
Dry Eye Syndrome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Break Up

Industri semen diketahui menghasilkan polutan udara yang berbahaya bagi kesehatan yang dapat berupa debu dan memiliki tingkat toksisitas yang paling tinggi dibanding polutan udara lainnya. Paparan debu semen jangka panjang menyebabkan terjadinya inflamasi subklinis kronik yang dapat mempengaruhi transdiferensiasi epitel konyungtiva dan densitas sel goblet yang kemudian dapat menyebabkan timbulnya gejala dry eye syndrome. Penelitian ini berupa analytic cross sectional study pada dua populasi yaitu kelompok terpapar dan tidak terpapar emisi debu pabrik semen. Semua sampel penelitian dari dua populasi menjalani pemeriksaan pH tear film, Schirmer, Ferning dan tear break up time.Terdapat peningkatan nilai pH tear film yang bermakna pada penduduk di kelompok terpapar Terdapat juga penurunan kualitas Ferning yang bermakna pada penduduk di kelompok terpapar yang didominasi tipe III. Sedangkan hasil pemeriksaan Schirmer dan TBUT masih dalam batas normal dan tidak terdapat perbedaan yang bermakna antara kedua kelompok. Pada pemeriksaan sitologi impresi pada kelompok terpapar didapatkan densitas sel goblet yang masih dalam batas normal dan juga tidak didapatkan metaplasia pada sel epitel konjungtiva. Terdapat peningkatan rerata nilai pH tear film dan penurunan kualitas lapisan musin tear film yang bermakna pada masyarakat yang terpapar emisi debu semen namun tidak disertai kerusakan permukaan okular dan peningkatan kejadian dry eye yang bermakna.

scholarly journals Association of dry eye syndrome with oral Isotretinoin therapy for severe nodulocystic acne and recalcitrant acne vulgaris

2015 ◽  
Vol 2 (1) ◽  
pp. 12-16
Author(s):  
Amit Amatya ◽  
Ranjana Sharma ◽  
Dharmendra Kumar Karn ◽  
Raju Kaiti
Keyword(s):  
Dry Eye ◽  
Acne Vulgaris ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Mean Values ◽  
Oral Isotretinoin ◽  
The Mean ◽  
Break Up ◽  
Isotretinoin Therapy

Introduction: Oral isotretinoin was registered in Nepal almost three decades later its first introduction in USA. It remains the most clinically effective medication for acne. Dry eye syndrome is a ‘certain’ adverse effect of oral isotretinoin therapy which can be validated by tear film break up time and Schirmer I tests.Methods: Fifty patients aged above 12 years presenting to dermatology outpatient department of Dhulikhel Hospital with severe nodulocystic acne or recalcitrant acne vulgaris not responding to three months of systemic antibiotics along with topical agents were included. Tear film break up time and Schirmer I tests before, at 45 and 90 days, and one month after taking oral isotretinoin were performed to study association of dry eye syndrome due to oral isotretinoin.Results: Both eyes of fifty selected patients were sampled. Baseline mean tear film break up time of 12.37±4.17 sec decreased to 9.69±3.70 sec, 9.09±3.77 sec and 10.67±3.50 sec at 45 and 90 days and on follow up, respectively. Likewise, baseline mean Schirmer I value of 16.68±8.73 mm decreased to 12.26±7.64 mm, 11.49±8.07 mm and 11.76±8.11 mm respectively at 45 and 90 days and on follow up. The differences between the mean values were analyzed using paired samples T test and all were statistically significant except between the mean Schirmer values at 90 days and on follow up.Conclusions: Abnormal mean tear break up time at 45 and 90 days in this study suggests that dry eye syndrome was caused by oral isotretinoin during acne therapy but tends to revert to normal on cessation.Journal of Patan Academy of Health Sciences, Vol. 2, No. 1, 2015. page:12-16

scholarly journals A CLINICAL AND ANALYTICAL STUDY OF CORRELATION BETWEEN DRY EYE SYNDROME AND REFRACTIVE ERROR IN YOUNG ADULT PATIENTS ATTENDING OPHTHALMOLOGY DEPARTMENT, MBS HOSPITAL KOTA.

2020 ◽  
pp. 1-4
Author(s):  
Jaishree Singh ◽  
Parneet Jat ◽  
Ashok Meena
Keyword(s):  
Young Adult ◽  
Dry Eye ◽  
Rose Bengal ◽  
Tear Film ◽  
Cross Sectional Study ◽  
Dry Eye Syndrome ◽  
P Value ◽  
Refractive Errors ◽  
Cross Sectional ◽  
Department Of Ophthalmology

Objectives:- This study aims to add new information about the DES in young adult by examining the correlation between dry eye syndrome and refractive errors. Methods: In this cross sectional study, a total of 200 participants in the age range of 18 to 35 years and who were free of ocular surface disease, were taken from the patients attending outpatient Department of Ophthalmology, MBS Hospital Kota. Refraction was defined by the spherical equivalent (SE) as the following: 74 emmetropic eyes (±0.50 SE), 76 myopic eyes (≤−0.75 SE), and 50 hyperopic eyes (≥+0.75SE). All participants underwent full ophthalmic examinations assessing their refractive status and dryness level including tear film break up time, Rose Bengal staining and schirmer test. Results: Prevalence of dry eye syndrome was 25.5% in this age group. In our study the prevalence of dry eye was 22.97%, 31.57%, and 20.00% in emmetropes, myopes, and hypermetropes, respectively (p value =0.28) and compared to emmetropes , prevalence of dry eye was higher in those with refractive errors (22.97% and 26.98% respectively). Mean Tear breakup time in seconds showed shorter time in eyes of myopic and hyperopic individuals compared to emmetropia. Mean Rose Bengal staining score showed less in emmetropic individuals compared to myopic and hyperopic. Conclusion: The current results succeeded to demonstrate a correlation between refractive errors and dryness level.

scholarly journals A comparison of the occurence of dry eye between arthritic and non-arthritic subjects

2013 ◽  
Vol 72 (1) ◽  
Author(s):  
E. Oghre ◽  
O. M. Amiebenomo
Keyword(s):  
Rheumatoid Arthritis ◽  
Dry Eye ◽  
Tear Film ◽  
T Test ◽  
Significant Difference ◽  
Eye Symptoms ◽  
Time Test ◽  
Break Up ◽  
Age Range ◽  
Breakup Time

Various studies have reported that dry eye is a common occurrence in patients with rheumatoid arthritis but not much has been done to determine its occurrence in other forms of arthritis. Thisstudy was designed to compare the symptoms of dry eye, tear film breakup time and tear production respectively in arthritic and non-arthritic subjects and also between rheumatoid arthritic patients and patients with other forms of arthritis. A total of 106 subjects within the age range of 41-90 years were included. Fifty-nine were non-arthritic with mean age and standard deviation (SD) of 58.2 ± 11.9 years, while 47 had arthritis with mean age and SD of 63.4 ± 13.3 years. Of the 47 arthritic patients 34 had osteoarthritis, 10 had rheumatoid arthritis, two had ankylosing spondylitis and one had gout. Subjects were evaluated using a McMonnies and Ho Dry Eye Questionnaire, invasive tear break-up-time test, Schirmer I test and fluorescein staining. The percentage of subjects with dry eyesymptoms in both the arthritic and non-arthritic groups was quite small (<10%) however, there was a statistically significant difference in dry eye symptoms between both groups (Mann-Whitney: U = 1035.5, p = 0.025) even though both groups were largely asymptomatic. There was no significant difference in tear breakup time (Mann-Whitney:  U = 175,  p  > 0.05), or tear quantity respectively (Unpaired  t-test: p > 0.05) between both groups. Also, there was no statistically significant difference in symptoms of dry eye, tear break up time, or tear quantity respectively between rheumatoid arthritis and other forms of arthritis (Unpaired t-test: p > 0.05). In conclusion, the occurrence of dry eye is largely independent of the presence of arthritis even though arthritic subjects may be slightly more symptomatic and the presence of dry eye is independent of the form of arthritis.  (S Afr Optom 2013 72(1) 34-40)

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