Spinal Myoclonus after Sub-Arachnoid Block

2021 ◽  
Vol 15 (12) ◽  
pp. 3353-3354
Author(s):  
Mamoona Shaikh ◽  
Jamil Ahmed ◽  
Kauser Shaikh ◽  
Shahid Khan ◽  
Ghulam Nabi Mmeon
Keyword(s):  
Magnesium Sulphate ◽  
Neuraxial Block ◽  
Spinal Myoclonus

Spinal myoclonus is a rare and less known sequel e after central neuraxial blocks and hereby we present a case of 68 yrs old lady undergoing removal of infected femur implant under sub-arachnoid block (SAB), developing myoclonus after the procedure ended but before regression of block. It was treated successfully with an infusion of lignocaine and magnesium sulphate. The patient was called in for follow-up after one week and had no any complains thereafter. Keywords: Spinal myoclonus, sub-arachnoid block, neuraxial block

Influence of maternal magnesium sulphate and ritodrine treatment on the neonate: a study with six-month follow-up

2007 ◽  
Vol 88 (10) ◽  
pp. 1142-1146 ◽  
Author(s):  
T Rantonen ◽  
U Ekblad ◽  
J Grönlund ◽  
H Rikalainen ◽  
I Välimäki ◽  
...  
Keyword(s):  
Magnesium Sulphate

scholarly journals Magnesium Sulphate Treated Severely Asphyxiated Neonates, Their Characteristic and Outcome

2019 ◽  
pp. 1-9
Author(s):  
Simon Pius ◽  
Mustapha Bello ◽  
Jose Pwavimbo Ambe ◽  
Machoko Yenti ◽  
Rhoda Genesis ◽  
...  
Keyword(s):  
Breast Feeding ◽  
Enteral Feeding ◽  
Magnesium Sulphate ◽  
Perinatal Asphyxia ◽  
Controlled Trial ◽  
Neonatal Morbidity ◽  
One Year ◽  
Almost All ◽  
Full Enteral Feeding

Introduction: Perinatal asphyxia is a common neonatal problem and contributes significantly to neonatal morbidity and mortality. Encephalopathy occurs in 50% to 60% of patients with severe perinatal asphyxia. Moderate hypoxic ischaemic encephalopathy (HIE), 10% to 20% die and 30% to 40% develop neurodeficits, whereas 50% of those with severe HIE die and almost all survivors develop neurodeficits. The systematic administration of magnesium sulphate (MgSO4) after perinatal asphyxia has shown effective resolution of neuronal injury.  We have conducted this study to validate the effect of MgSO4 in severely asphyxiated neonates, so as to utilize its benefits on ameliorating the outcome associated with severe perinatal asphyxia/HIE. Objective of the Study: To determine the characteristics and outcome of magnesium sulphate on neurological outcome in severe perinatal asphyxia Materials and Methods: A prospective interventional study of magnesium sulphate treatment of neonates with severe perinatal asphyxia conducted over one year period from 1st August 2017 to 31st July 2018. Results: Of the 52 neonates, male 34 while there 18 female giving a ratio of (M: F is 1:1.8).  There were 30 (57.7%) in-born and 22 (42.3%) out-born, the total asphyxia cases (30/144) giving the incidence of 20.8% among in born. About one half (55.8%) of the patients commenced MgSO4 therapy at < 6 hours after birth, while 30.6% and 16.6% commenced MgSO4 therapy at 6 - < 24 hours and > 24 hours after birth respectively. About one half (49.0%) commenced enteral feeding within 5 – 7 days while 36.7% and 14.3% commenced enteral feeding at 4 < days and at > 7 days respectively. Majority of the patients commenced full enteral feeding at either between 5 – 7 days or > 7 days while only 36.7% of the neonates commenced full enteral feeding before 5 days. Equally, primary outcome, fully recovered and initiation breast feeding. Conclusion: Of the fifty two patients managed, 5 (9.6%) died during the treatment period after 8th day of admission and at follow up, while 47 (90.4%) survived. Also greater 50% of the survivors commenced breast feeding within five days of admission and were clinical normal at follow up clinic. Whether this coincidental or a true effect of MgSo4, a future prospective randomized controlled trial may make the picture clearer

scholarly journals Neuroaxial anesthesia caused paraplegia: a case report

2021 ◽  
Author(s):  
Luis David Cortés-Badillo ◽  
Agustín Reyes-Gutiérrez ◽  
Óscar Gómez-Chaccón ◽  
Luis David Olivera-León ◽  
Elsy Daniela Olivera-León ◽  
...  
Keyword(s):  
Femur Fracture ◽  
Functional Limitation ◽  
Lower Limbs ◽  
Intravenous Sedation ◽  
Neuraxial Block ◽  
Epidural Fat ◽  
Disc Level ◽  
Suicide Plan ◽  
At Home

Patients who undergo; anesthesia, neuraxial analgesia, or some type of neuraxial blockage are exposed to multiple complications. 33-year-old male patient, suffers a femur fracture with a long oblique trace causing pain and functional limitation for movements. Surgical resolution is determined using neuraxial block at L2-L3 level, and intravenous sedation. During his postoperative follow-up, a decrease in strength was confirmed in the lower limbs with 0/5 on the Daniels scale, 100% sensitivity without sphincter control, steroids were prescribed along with magnetic resonance imaging and a neurosurgical evaluation was requested. The MRI shows bulging of the fibrous annulus that obliterates the epidural fat and makes contact with the thecal sac in the L5-S1 intervertebral disc level. The neurosurgery service prescribes rehabilitation sessions at home, electrostimulation and neuropathic medications. Patient was discharged with rehabilitation sessions at home and medical treatment. In his last consultation, an evaluation from the psychiatry department was requested for ideas of disability, hopelessness, fantasies of death without a suicide plan related to limitations and loss of functionality. Patient does not return to external follow-up, cannot be located.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

Brief summary of Kleť photographic search programme for minor planets

1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec
Keyword(s):  
Ccd Camera ◽  
Minor Planet ◽  
Minor Planets ◽  
Main Belt

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.

Intranuclear Crystals in Regenerating Canine Kidneys

1973 ◽  
Vol 31 ◽  
pp. 412-413
Author(s):  
D.G. Osborne ◽  
L.J. McCormack ◽  
M.O. Magnusson ◽  
W.S. Kiser
Keyword(s):  
Epithelial Cell ◽  
Epithelial Cells ◽  
Tubular Epithelial Cell ◽  
Tubular Epithelial Cells ◽  
Cell Nuclei ◽  
Crystalline Structures ◽  
Small Crystals ◽  
Membrane Bound

During a project in which regenerative changes were studied in autotransplanted canine kidneys, intranuclear crystals were seen in a small number of tubular epithelial cells. These crystalline structures were seen in the control specimens and also in regenerating specimens; the main differences being in size and number of them. The control specimens showed a few tubular epithelial cell nuclei almost completely occupied by large crystals that were not membrane bound. Subsequent follow-up biopsies of the same kidneys contained similar intranuclear crystals but of a much smaller size. Some of these nuclei contained several small crystals. The small crystals occurred at one week following transplantation and were seen even four weeks following transplantation. As time passed, the small crystals appeared to fuse to form larger crystals.

Electron Microscopy of Human Gallstones

1971 ◽  
Vol 29 ◽  
pp. 296-297
Author(s):  
C. Wolpers ◽  
R. Blaschke
Keyword(s):  
Electron Microscopy ◽  
Room Temperature ◽  
Bile Pigment ◽  
X Ray Diffraction ◽  
Triclinic Crystal System ◽  
X Ray ◽  
Follow Up Study ◽  
Infra Red ◽  
Main Components

Scanning microscopy was used to study the surface of human gallstones and the surface of fractures. The specimens were obtained by operation, washed with water, dried at room temperature and shadowcasted with carbon and aluminum. Most of the specimens belong to patients from a series of X-ray follow-up study, examined during the last twenty years. So it was possible to evaluate approximately the age of these gallstones and to get information on the intensity of growing and solving.Cholesterol, a group of bile pigment substances and different salts of calcium, are the main components of human gallstones. By X-ray diffraction technique, infra-red spectroscopy and by chemical analysis it was demonstrated that all three components can be found in any gallstone. In the presence of water cholesterol crystallizes in pane-like plates of the triclinic crystal system.

Articulatory Intervention for the Visually Impaired

1979 ◽  
Vol 10 (3) ◽  
pp. 139-144
Author(s):  
Cheri L. Florance ◽  
Judith O’Keefe
Keyword(s):  
High School ◽  
High School Students ◽  
Behavior Change ◽  
Visually Impaired ◽  
School Students ◽  
Handicapped Children ◽  
Paired Stimuli ◽  
Visually Handicapped ◽  
Parent Program

A modification of the Paired-Stimuli Parent Program (Florance, 1977) was adapted for the treatment of articulatory errors of visually handicapped children. Blind high school students served as clinical aides. A discussion of treatment methodology, and the results of administrating the program to 32 children, including a two-year follow-up evaluation to measure permanence of behavior change, is presented.

What Does Evidence-Based Practice Mean to You? A Follow-Up Study Examining School-Based Speech-Language Pathologists' Perspectives on Evidence-Based Practice

2020 ◽  
Vol 29 (2) ◽  
pp. 688-704
Author(s):  
Katrina Fulcher-Rood ◽  
Anny Castilla-Earls ◽  
Jeff Higginbotham
Keyword(s):  
Clinical Practice ◽  
Research Evidence ◽  
Evidence Based Practice ◽  
Evidence Based ◽  
Clinical Expertise ◽  
Speech Language Pathologists ◽  
School Based ◽  
Research Findings ◽  
Ebp Implementation

Purpose The current investigation is a follow-up from a previous study examining child language diagnostic decision making in school-based speech-language pathologists (SLPs). The purpose of this study was to examine the SLPs' perspectives regarding the use of evidence-based practice (EBP) in their clinical work. Method Semistructured phone interviews were conducted with 25 school-based SLPs who previously participated in an earlier study by Fulcher-Rood et al. 2018). SLPs were asked questions regarding their definition of EBP, the value of research evidence, contexts in which they implement scientific literature in clinical practice, and the barriers to implementing EBP. Results SLPs' definitions of EBP differed from current definitions, in that SLPs only included the use of research findings. SLPs seem to discuss EBP as it relates to treatment and not assessment. Reported barriers to EBP implementation were insufficient time, limited funding, and restrictions from their employment setting. SLPs found it difficult to translate research findings to clinical practice. SLPs implemented external research evidence when they did not have enough clinical expertise regarding a specific client or when they needed scientific evidence to support a strategy they used. Conclusions SLPs appear to use EBP for specific reasons and not for every clinical decision they make. In addition, SLPs rely on EBP for treatment decisions and not for assessment decisions. Educational systems potentially present other challenges that need to be considered for EBP implementation. Considerations for implementation science and the research-to-practice gap are discussed.

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