scholarly journals Original article. Repeatability assessment of the New Numbers Contrast Sensitivity Chart

2014 ◽  
Vol 8 (3) ◽  
pp. 361-369
Author(s):  
Bharkbhum Khambhiphant ◽  
Sunee Chansangpetch ◽  
Wasee Tulvatana ◽  
Mathu Busayarat
Keyword(s):  
Contrast Sensitivity ◽  
Narrow Range ◽  
Primary Language ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Plot Analysis ◽  
Good Repeatability ◽  
The Mean ◽  
Mean Differences ◽  
The Right

Abstract Background: The validity and agreement of the New Numbers Contrast Sensitivity Chart with the original Mars chart have been found to be good. The two charts can be used interchangeably; however, evidence of the repeatability of the new chart remains to be sought. This study was to assess the repeatability of the New Numbers Contrast Sensitivity Chart. Objectives: We assessed the repeatability of the Numbers Contrast Sensitivity Chart. Methods: Two hundred subjects from the ophthalmic clinic of the King Chulalongkorn Memorial Hospital, who were able to communicate and read Arabic numerals were recruited. The contrast sensitivity (CS) scores were collected by reading the same Numbers Contrast Sensitivity Chart in the same environment with each eye and both eyes ten minutes apart. The repeatability of the CS score was assessed by Bland-Altman plot analysis. Results: The visual acuity of subjects with variety in diagnoses ranged from 20/480 to 20/20. The mean differences were -0.006, -0.008, -0.002 log CS and the coefficients of repeatability were 0.155, 0.141, and 0.093 for the right eye, left eye, and both eyes, respectively. The plots showed a narrow range of 95% limit of agreement, which were (+0.146, -0.159) in the right eye, (+0.130, -0.147) in the left eye, and (+0.089, -0.093) in both eyes. Conclusions: The New Numbers Contrast Sensitivity Chart has good repeatability. With proven good validity and repeatability, this easy and convenient numbers chart is beneficial for practical use in a clinical setting where English is not used as the primary language.

Effect of manual eyelid manipulation on intraocular pressure measurement by rebound tonometry

2018 ◽  
Vol 102 (11) ◽  
pp. 1515-1519 ◽  
Author(s):  
Sung Uk Baek ◽  
Ahnul Ha ◽  
Young Kook Kim ◽  
Jin Wook Jeoung ◽  
Ki Ho Park
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Mean Value ◽  
Applanation Tonometry ◽  
Palpebral Fissure ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Rebound Tonometry ◽  
The Mean

Background/aimsTo investigate the effect of eyelid manipulation on the measurement of intraocular pressure (IOP) using two different tonometries (rebound tonometry (RT) vs Goldmann applanation tonometry (GAT)).Methods103 patients with primary open-angle glaucoma were prospectively enrolled. For all of the patients, IOP measurements were performed in three different ways: (1) RT with lid manipulation (LM), (2) RT without LM and (3) GAT. The order of the three measurements was randomly selected. Additionally, the palpebral fissure height (PFH; elliptical space between upper and lower eyelids) was measured.ResultsThe mean value of IOP measured by GAT was 13.97±2.80 mm Hg, which was not significantly different from that by RT without LM (13.75±2.44 mm Hg; P=0.096), but which was significantly lower than that by RT with LM (15.21±2.91 mm Hg; P<0.001). On a Bland-Altman plot, RT with LM was overestimated relative to GAT (mean: −1.5) and RT without LM (mean: −1.2). Among the high IOPs (>20 mm Hg), interestingly, those measured by RT without LM were significantly lower than those measured by GAT (P<0.001). In the subgroup analysis of PFH, the smaller the PFH, the more exaggerated the IOP difference between GAT (P=0.014) and RT with LM (P<0.001).ConclusionRT-measured IOP was significantly exaggerated when manipulation was applied to the eyelid. This overall trend was more pronounced when PFH was small. GAT-measured IOP, meanwhile, showed a good correlation with IOP measured using RT without LM.

scholarly journals Correlation of Corneal Thickness Measurements Between Tono-pachymeter and Scheimpflug- Placido Topography

2021 ◽  
Vol 16 (2) ◽  
pp. 161-167
Author(s):  
Zeynep Eylül Ercan ◽  
Keyword(s):  
Corneal Thickness ◽  
Age Groups ◽  
Limits Of Agreement ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Significant Relationships ◽  
Plot Analysis ◽  
Group 2 ◽  
Thickness Measurements ◽  
Group 1

Central corneal thickness (CCT) measurements are important for diagnosis, treatment, and surgery planning in ophthalmology. The purpose of this study was to see whether CCT measurements taken with Tono-pachymeter and Scheimpflug- Placido Topography had any significant differences. Tono-pachymeter and topography CCT measurements were taken (n=400). Inter-measurement agreement between them was determined using Bland-Altman Plot analysis. Age groups were also formed as group 1 (aged 18-50 years, 94 males, 106 females) and group 2 (age >51 years, 100 males, 100 females). Mean CCTs measured by Tonopachymeter and topography were 563.77 +±26.43 and 560.88 + 26.341 microns. Bland-Altman Plot analysis showed in total, 13 were above the upper limit and 5 were under the minimum limit of agreement with regression analysis showing no significant relationships (p=0.213). Group 1 had 7 above and 2 below from the limits of agreement. Group two had 9 above and 2 below from the limits of agreement. Both groups showed insignificant differences between devices (p=0.07 and p=0.86). Tono-pachymeter and Scheimpflug-Placido Topography give reliable CCT results within each other. However, since the limit of agreement ranges can still affect one-to-one patient evaluations, we recommend clinics that use these devices to not interchange measurements in practice.

scholarly journals Analysis of hard tissue facial symmetry after unilateral mandibular reconstruction

2021 ◽  
Vol 43 (1) ◽  
Author(s):  
Mohamad Saleh Khaghaninejad ◽  
Leila Khojastepour ◽  
Hanie Ahmadi ◽  
Saeid Tavanafar ◽  
Alireza Ebrahimi ◽  
...  
Keyword(s):  
Bilateral Symmetry ◽  
Asymmetry Index ◽  
Mandibular Reconstruction ◽  
Control Group ◽  
Study Group ◽  
The Mean ◽  
The Difference ◽  
Bilateral Differences ◽  
Mean Differences ◽  
The Right

Abstract Background This study aimed to determine how successful reconstruction of the mandible can recover the symmetry. Materials and methods All patients who underwent surgical treatment for unilateral mandibular reconstruction in 4 years were retrospectively examined. Bilateral differences of gonion (GO) positions were measured in 3 dimensions based on immediate postoperative computed tomography. The data collected was analyzed in 3 ways: First, the comparison of bilateral differences of GO in 3 dimensions. Second, the mean Asymmetry Index in control subjects was used to divide all cases into three groups: “Symmetry,” “Asymmetry,” and “Marked asymmetry.” Third, “maximum normal asymmetry” was calculated, and all cases were categorized as below and above maximum normal asymmetry. The difference between two gonial angles was used to determine the amount of asymmetry. Results Forty-seven patients and 47 normal adults were enrolled. The mean bilateral GO difference in the control group was higher than in the study group patients, but it was not statistically significant. The mean Asymmetry Index for the control group was not also significantly higher than the study cases. The study group was “Symmetric” in 78.7% of the cases whereas the control group in 91.4%, 19.1% of the study group and 8.5% of controls were “Asymmetric,” and 2.1% of study cases and 0% of controls were “Markedly Asymmetric.” Maximum normal asymmetry was 82.9% in the study group and 97.8% in the control group. The mean differences between the right and left gonial angles were higher in the study group, but it was not significant (P = 0.1). Conclusions Our study’s results showed that bilateral symmetry in mandibular reconstruction patients was satisfactory and similar to the normal individuals.

scholarly journals Frontal plane knee alignment among normal northern Nigerian adults: A radiographic study

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Abdullahi Suleiman Gwani ◽  
Eduitem Sunday Otong ◽  
Sani Abubakar Bello ◽  
Hamza Mustapha Ahmed ◽  
Dlama Zira Joseph ◽  
...  
Keyword(s):  
Frontal Plane ◽  
Equal Weight ◽  
Knee Alignment ◽  
Male Population ◽  
Female Population ◽  
Significant Difference ◽  
History Of ◽  
The Mean ◽  
Mean Differences ◽  
The Right

Studies have shown that knee alignment parameters differ among races. However, to our knowledge, radiographic frontal plane knee alignment has not been studied in normal northern Nigerian adults. The objective of this study was therefore to determine the frontal plane knee alignment in normal northern Nigerian adults. This study recruited a total of 59 consented subjects (44 males, 15 females). The entire subjects are without any history of lower extremity deformity. Anteroposterior radiographs of both knees with the patella positioned straight ahead were obtained from each participant while standing in a relaxed bipedal stance and placing equal weight on each limb. Alignment was assessed by measuring the tibiofemoral angle (TFA), distal femoral angle (DFA) and proximal tibial angle (PTA). The angles were measured with the aid of a universal plastic goniometre and a plastic ruler. Descriptive statistics of the alignment parameters, independent and paired t-test were computed. In the male population, the mean (standard deviation) obtained were 179.06 (3.87)o for the TFA, 85.94 (3.03 o for the DFA and 89.27 (3.26)o for the PTA. In the female population, the values were 179.53 (3.38)o for the TFA, 86.40 (2.97)o for the DFA and 89.27 (2.15)o for the PTA. No significant mean difference was observed between genders in all the parameters. The TFA does not show any significant difference between the right and left angle regardless of gender. However, significant mean differences were observed in the DFA and PTA of males and combined population. No significant difference was observed in the DFA and PTA of females. Accordingly, northern Nigerian adults may have varus knee alignment compared to other races. Thus, this pre-existing varus alignment should be taken into consideration during clinical examination, preoperative planning and postoperative evaluations of knee deformities in this population.

Reliability of Shoulder Symptom Recall after 1 Year in a Retrospective Application of the Oxford Shoulder Score

2012 ◽  
Vol 4 (4) ◽  
pp. 255-258
Author(s):  
Michael Held ◽  
Steve Roche ◽  
Basil Vrettos ◽  
Maritz Laubscher ◽  
Johan Walters
Keyword(s):  
Shoulder Function ◽  
Test Pair ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Individual Level ◽  
Oxford Shoulder Score ◽  
The Mean ◽  
One Year ◽  
The Individual ◽  
Shoulder Score

Background The accuracy of retrospective recall of shoulder symptoms has not been well documented. This prospective study assesses the ability of patients to recall their preoperative shoulder function one year after a surgical intervention, using the Oxford Shoulder Score (OSS). Methods 35 patients completed an OSS before undergoing shoulder surgery. One year later, patients were asked to recall their symptoms prior to their surgery. The recalled OSS of the patients as a group was compared to their preoperative score. The recall bias of each test pair was assessed with a Bland – Altman plot. Results On recall after a mean of 12.6 months, the mean OSS from the index assessment increased from 36.25 to 38.25 points. The mean difference of 2 points for the patients as a group was not significant (p = 0.14). The statistical limits of agreement of the Bland – Altman plot were set at +/-2 SD = 14.079 points. The plotted points showed fair correlation between each individual test pair. Conclusion The recall of symptoms of a large group of patients at 1 year after the index intervention appears to have a moderate correlation with the preoperative scoring. Although statistically acceptable, this limit of agreement is much larger than the 4.5-point difference, established to be clinically relevant in prior studies. The variation seen within the scores at the individual level suggests that these data cannot be used as a retrospective tool.

scholarly journals MRI follow-up for pancreatic intraductal papillary mucinous neoplasm: an ultrashort versus long protocol

2021 ◽  
Author(s):  
Katarina Johansson ◽  
Harri Mustonen ◽  
Heini Nieminen ◽  
Caj Haglund ◽  
Tiina E. Lehtimäki ◽  
...  
Keyword(s):  
Interobserver Agreement ◽  
Pancreatic Tumors ◽  
Altman Plot ◽  
Mean Values ◽  
Mean Size ◽  
The Mean ◽  
Mean Differences ◽  
Mural Nodules ◽  
Long Protocol

Abstract Purpose To evaluate whether an ultrashort-protocol (USP) MRI including only T2-weighted HASTE axial and 3D MRCP SPACE sequences adequately measures the largest diameter of the largest cyst and the main pancreatic duct (MPD) and identifies worrisome features (WF) and high-risk stigmata (HRS) when compared to longer protocols (LP, long protocol; SP, short protocol; S-LP, short or long protocol). We also calculated reductions in costs associated with USP. Methods This retrospective study included 183 IPMN patients. Two radiologists compared two imaging sets (USP versus S-LP) per patient, comparing the mean values of the largest cyst and MPD and agreement regarding the presence or absence of cystic or MPD mural nodules and solid pancreatic tumors. The interobserver agreement for cystic mural nodules and WF/HRS was evaluated, using the Bland-Altman plot and Cohen’s Kappa. Results A total of 112 IPMN patients were evaluated. For detecting cysts or MPD nodules, WF/HRS, and solid pancreatic tumors, USP and S-LP coincided in 94.9%, 99.1%, 92.4%, and 99.1% of cases, respectively. Both USP and S-LP identified all true cystic mural nodules. The mean size of the largest cyst and MPD was 19.48/19.67 mm and 3.24/3.33 mm using USP versus S-LP, while the mean differences for USP versus S-LP were 0.19 mm and 0.08 mm. The USP cost was 39% of LP cost and 77% of SP. Interobserver agreement was moderate to strong. Conclusions For IPMN surveillance, an ultrashort-protocol MRI provides nearly identical information to the more expensive longer protocols. Graphical abstract

Cervical length at 31–34 weeks of gestation: transvaginal vs. transperineal ultrasonographic approach

2019 ◽  
Vol 47 (8) ◽  
pp. 817-821 ◽  
Author(s):  
Ioannis Tsakiridis ◽  
Themistoklis Dagklis ◽  
Apostolos Mamopoulos ◽  
Angeliki Gerede ◽  
Apostolos Athanasiadis
Keyword(s):  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Close Correlation ◽  
Cervical Length ◽  
Tolerance Interval ◽  
Pearson Correlation Coefficient ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Paired Samples ◽  
The Mean

Abstract Objectives To investigate the correlation between transperineal (TP) and transvaginal (TV) ultrasonography in the measurement of cervical length (CL) in the third trimester of pregnancy. Methods In this prospective study, CL measurements were conducted in women between 31 and 34 weeks of gestation by both the TP and TV approaches. A comparison of the measurements was made between the two techniques. The Pearson correlation coefficient, the paired samples t-test and Bland-Altman plot were used. Results In total, 240 women participated in the study. The CL was successfully measured transvaginally in all cases and transperineally in 229 (95.4%) of the cases. The mean TV CL was 32.8 ± 8.2 mm and the mean TP CL was 32.5 ± 8.1 mm. In the 229 cases with paired measurements, the Pearson correlation coefficient was 0.964. No significant differences in mean CL were identified between the two methods (t = 1.805; P = 0.072). In the Bland-Altman plot, the difference between the paired means was 0.26 mm and the 95% tolerance interval for any given paired observation (TV CL–TP CL) was −4.05 to 4.57 mm. Conclusion The findings of this study suggest that at 31–34 weeks of gestation the cervix can be visualized adequately by both the TV and TP sonography in about 95% of cases. The TP CL measurements demonstrate a close correlation with the TV measurements. TP ultrasound is a feasible alternative, especially in cases where the use of the vaginal transducer should be minimized or is not acceptable by women.

Level of agreement between sPRO and Kubios software in the analysis of R-R intervals obtained by a chest strap

2021 ◽  
pp. 175433712110311
Author(s):  
José Pino-Ortega ◽  
Markel Rico-González ◽  
Petrus Gantois ◽  
Fabio Y Nakamura
Keyword(s):  
Time Domain ◽  
Time Course ◽  
Intraclass Correlation ◽  
Systematic Bias ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Software Packages ◽  
The Mean ◽  
Improved Performance ◽  
Level Of Agreement

Heart rate variability (HRV) is becoming one of the most commonly used tools for tracking the time course of training adaptation/maladaptation of athletes and setting optimal training loads, leading to improved performance. The aim of this study was to compare Realtrack Systems manufacturer software (sPRO) with the Kubios HRV Standard. R-R intervals were recorded from 48 athletes using a chest strap synchronized to WIMU PRO™ device for 10 min to analyze time-domain HRV indices, located between the scapulae. Time-domain HRV indices analyzed included the square root of the mean squared differences of successive R-R intervals (RMSSD), standard deviation of normal R-R intervals (SDNN), and percentage of adjacent R-R intervals that differ from each other by more than 50 ms (pNN50). The intraclass correlation test and Bland-Altman plot were used to verify the agreement between the sPRO and the Kubios HRV Standard software for examining time-domain HRV indices. The intraclass correlation coefficient showed high values of agreement of R-R intervals and time-domain HRV indices between the two software options (RMSSD, SDNN, and pNN50; ICC > 0.951). The Bland-Altman plot showed low bias for all the HRV indices analyzed (bias = −0.11 to −1.08). In addition, no systematic bias was found between the residual of the mean difference and the average values of the two software packages ( p > 0.05). Therefore, both software options can be used interchangeably for analyzing time-domain HRV records.

scholarly journals A multicenter study of interocular symmetry of corneal biometrics in Chinese myopic patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Guihua Xu ◽  
Yijun Hu ◽  
Shanqing Zhu ◽  
Yunxiang Guo ◽  
Lu Xiong ◽  
...  
Keyword(s):  
Corneal Thickness ◽  
Intraclass Correlation ◽  
Corneal Astigmatism ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Corneal Volume ◽  
Corneal Asphericity ◽  
The Right ◽  
Spearman’S Correlation ◽  
Corneal Diameter

AbstractIt is essential to know the normal range of the interocular symmetry of the cornea (ISC) for keratoconus diagnosis and corneal substitutes design. In the present study we investigated the interocular symmetry of corneal biometrics in 6,644 Chinese myopic patients from multiple ophthalmic centers. Corneal biometrics of both eyes were exported from the Pentacam instrument. Interocular symmetry of the corneal biometrics was analyzed by Spearman’s correlation test, intraclass correlation coefficient (ICC) analysis and Bland–Altman plot. Significantly strong interocular correlations were found in anterior and posterior corneal curvatures, corneal diameter, corneal thickness, corneal volume, corneal eccentricity, and corneal asphericity (r = 0.87–0.98, all P < 0.001). Moderate interocular correlations were observed in whole corneal astigmatism (r = 0.78) and posterior corneal astigmatism (r = 0.73). ICC between the right and left eyes was 0.94–0.98 for anterior and posterior corneal curvatures, corneal diameter, corneal thickness and corneal volume, 0.80–0.88 for corneal eccentricity and asphericity, and 0.73–0.79 for corneal astigmatism (all P < 0.001). Bland–Altman plot showed that the 95% limit of agreement between both eyes was narrow and symmetric in most of the corneal biometrics, suggesting strong interocular agreements in these corneal biometrics. In conclusion, significant interocular symmetry of corneal biometrics is observed in Chinese myopia patients. Extra attention should be paid to patients with interocular corneal asymmetry.

scholarly journals A Head-to-head Comparison of the EQ-5D-3L Index Scores Derived from the Two EQ-5D-3L Value Sets for China

2022 ◽  
Author(s):  
Ruo-Yu Zhang ◽  
Wei Wang ◽  
Hui-Jun Zhou ◽  
Jianwei Xuan ◽  
Nan Luo ◽  
...  
Keyword(s):  
Index Score ◽  
Altman Plot ◽  
Health States ◽  
Minimum Important Difference ◽  
Absolute Level ◽  
Bland Altman Plot ◽  
Health Gains ◽  
The Mean ◽  
Two Indices ◽  
Value Sets

Abstract Background: Two EQ-5D-3L (3L) value sets (developed in 2014 and 2018) co-exist in China. The study examined the level of agreement between index scores for all the 243 health states derived from them at both absolute and relative levels and compared the responsiveness of the two indices. Methods: Intraclass correlations coefficient (ICC) and Bland-Altman plot were adopted to assess the degree of agreement between the two indices at the absolute level. Health gains for 29,403 possible transitions between pairs of 3L health states were calculated to assess the agreement at the relative level. Their responsiveness for the transitions was assessed using Cohen effect size.Results：The mean (standard deviation, SD) value was 0.427 (0.206) and 0.649 (0.189) for the 3L2014 and 3L2018 index scores, respectively. Although the ICC value showed good agreement (i.e., 0.896), 88.9% (216/243) of the points were beyond the minimum important difference limit according to the Bland-Altman plot. The mean health gains for the 29,403 health transitions was 0.234 (3L2014 index score) and 0.216 (3L2018 index score). The two indices predicted consistent transitions in 23,720 (80.7%) of 29,403 pairs. For the consistent pairs, Cohen effective size value was 1.05 (3L2014 index score) or 1.06 (3L2018 index score); and the 3L2014 index score only yielded 0.007 more utility gains. However, the results based on the two measures varied substantially according to the direction and magnitude of health change. Conclusion：The 3L2014 and 3L2018 index scores are not interchangeable. The choice between them is likely to influence QALYs estimations.

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