scholarly journals Influence of Smoking on the Location of Acute Myocardial Infarctions

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Rahel Alemu ◽  
Eileen E. Fuller ◽  
John F. Harper ◽  
Mark Feldman

Objective. To determine whether there is an association between smoking and the location of acute myocardial infarctions. Methods. Using a cohort from our hospital and published cohorts from Ireland, Uruguay, and Israel, we calculated odds of having an inferior wall as opposed to an anterior wall acute myocardial infarction among smokers and nonsmokers. Results. In our cohort, there was a higher proportion of smokers than nonsmokers in patients with inferior acute myocardial infarctions than in patients with anterior infarctions. This difference was also present in each of the other cohorts. Odds ratios for an inferior versus an anterior acute myocardial infarction among smokers ranged from 1.15 to 2.00 (median odds ratio, 1.32). When the cohorts were combined (), the pooled odds ratio for an inferior as opposed to an anterior acute myocardial infarction among smokers was 1.38 ( confidence interval, 1.20 to 1.58) (). Conclusions. Cigarette smoking increases the risk of inferior wall acute myocardial infarction more than the risk of anterior wall infarction. Smoking thus appears to adversely affect the right coronary arterial circulation to a greater extent than the left coronary arterial circulation by a mechanism not yet understood.

2013 ◽  
Vol 20 (03) ◽  
pp. 332-340
Author(s):  
ATIF SITWAT HAYAT ◽  
MUHAMMAD ADNAN BAWANY ◽  
JAWAD AHMED QADRI ◽  
Kiran Khalil

Background: Ischemic heart disease is the most common cause for complete heart block (CHB) and sudden death. Heartblocks may occur as complications of acute myocardial infarction (AMI) and are associated with increased mortality. The aim of thisstudy is to determine the frequency of complete heart block (CHB) in acute myocardial infarction at a tertiary care hospital. Place andduration: This study was conducted in Cardiology Department of Liaquat University of Medical and Health Sciences from 1st August2009 to 31st January 2010. Study Design: Cross sectional and descriptive study. Materials and Methods: ST segment elevation equal toor more than 1mm (0.1mv) in two of these leads II, III and aVF. Rise in serum creatinine kinase level (CPK Level) more than twice thenormal value along with CK-MB fraction more than 6% of CPK value. Patients with history of chest pain, shortness of breath, nausea,vomiting and unconsciousness were enrolled in the study. The cardiac enzymes tropinin T was also performed at bed side by venousblood sample. Results: Total of 87 patients were included, prevalence of heart blocks was 27.58%. Anterior wall MI was in 50(57.5%)patients. Of these, 13(54.2%) had complete heart block. Inferior wall MI was in 37(42.5%) cases, of these, 11(45.8%) were found withcomplete heart block. There was no significant difference between anterior wall MI and inferior wall MI with complete heart block (P value> 0.05). Mortality was 2.3% with anterior wall MI. Conclusions: Development of complete heart blocks has important prognosticsignificance. Complete heart block was frequent complication of myocardial infarction.


2019 ◽  
Vol 6 (3) ◽  
pp. 696
Author(s):  
Senthil Kumar Sampath ◽  
Vithiavathi Sivasubramanian ◽  
Satish Lakshminarayanan

Background: The electrocardiogram is the primary diagnostic tool to evaluate a patient with chest pain and suspected myocardial infarction. Anterior wall infarction due to occlusion of proximal LAD has worse prognosis compared to distal or branch vessel lesions. Diagnosis of anterior/inferior/posterior or lateral MI is based on patterns of ST deviation and risk assessment based on absolute magnitude of ST segment deviation or the width of QRS complexes. Although coronary angiography is the gold standard for determining the infarct related artery in acute myocardial infarction, ECG can be useful tool in identifying the culprit artery involved at the primary care.Methods: A prospective cross-sectional study was conducted in Aarupadai Veedu Medical College and Hospital. Standard 12 lead electrocardiograph were recorded for 50 patients at a speed of 25 mm/s and voltage of 10mm/mv. Patients who had acute inferior wall MI additional right pericardial leads were recorded (V3R and V4R). The recorded ECG was interpreted using the electrocardiographic algorithms of Zimet-baum PJ et al. An ST elevation or depression was considered significant only if it was >1mm.Results: The study result showed maximum specificity for LCx (100%) followed by RCA (92.67) and LAD (89.91). The sensitivity for identifying the culprit artery by ECG in acute myocardial infarction was 100% for both LAD and RCA coronary artery but 0% for LCx coronary artery. In case of LAD occlusion, the sensitivity is 100% for proximal LAD occlusion and 92.86%for distal LAD occlusion. The sensitivity and specificity for proximal and distal RCA is 100% and 80.43% respectively.Conclusions: ECG is an easily, widely available and non-invasive tool to localize the site of culprit artery in acute myocardial infarction.


2015 ◽  
Vol 12 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Radha Bhattarai ◽  
Sergey Anatolevich Sayganov

Background and Aim: New-onset atrial fibrillationfrequently complicates acute myocardial infarction.The incidence ranges from 6 - 21% “1”.We aim todetermine the incidence of atrial fibrillation in thesetting of acute myocardial infarction.Methods: This was a single center prospective study,conducted in the coronary care unit of Saint-PetersburgPokrovskaya city hospital, Russia, during the period,June 2013 to June 2014. Sixty consecutive patientsof acute myocardial infarction with atrial fibrillationwere included in this study. Onset, duration, and modeof termination of atrial fibrillation, clinical factorsassociated with its presentation and its relation withpatient outcome were evaluated.Results: Among the 60 patients 33 (55%) had inferiorwall myocardial infarction and 27 (45%) patientshad anterior wall myocardial infarction. In patientswith inferior wall myocardial infarction the onsetof atrial fibrillation occurred within 24 hours in 30(91%) patients, after 24 hour in 3 (9%) patients. Theepisode lasted for less than 24 hours in 12 (36%), andmore than 24 hours in 21 (64%) patients. In anteriorwall myocardial infarction atrial fibrillation occurredwithin 24 hours in 2 (7%) patients, on the second dayin 25 (93%). The episode lasted less than 24 hoursin 3 (11%), 48 hours in (85%), 72 hours in 1 (4%)patients. There was a significant difference in theonset and duration of atrial fibrillation in relation tothe location of infarction (P < 0.0001). Anterior wallmyocardial infarction was associated with late onsetof atrial fibrillation, increased frequency of heartfailure and higher CCU mortality.Conclusion: The onset of atrial fibrillation in anteriorwall myocardial infarction occurred later and lastedlonger in comparison to inferior wall myocardialinfarction. Increased incidence of heart failure andhigher CCU mortality was associated with anteriorwall myocardial infarction.DOI: http://dx.doi.org/10.3126/njh.v12i1.12327 Nepalese Heart Journal Vol.12(1) 2015: 15-20


Author(s):  
Krupal Reddy ◽  
Sandip Patil ◽  
Harminder Singh

Anomalous coronary anomalies are technically challenging. We describe the case of a 48-year-old male who suffered an acute inferior wall myocardial infarction due to thrombotic total occlusion in an anomalous right coronary artery arising from the contralateral aortic sinus.


2018 ◽  
Vol 25 (10) ◽  
pp. 1031-1039 ◽  
Author(s):  
Gerhard Sulo ◽  
Jannicke Igland ◽  
Stein Emil Vollset ◽  
Marta Ebbing ◽  
Grace M Egeland ◽  
...  

Background We updated the information on trends of incident acute myocardial infarction in Norway, focusing on whether the observed trends during 2001–2009 continued throughout 2014. Methods All incident (first) acute myocardial infarctions in Norwegian residents age 25 years and older were identified in the Cardiovascular Disease in Norway 1994–2014 project. We analysed overall and age group-specific (25–64 years, 65–84 years and 85 + years) trends by gender using Poisson regression analyses and report the average annual changes in rates with their 95% confidence intervals. Results During 2001–2014, 221,684 incident acute myocardial infarctions (59.4% men) were identified. Hospitalised cases accounted for 79.9% of all incident acute myocardial infarctions. Overall, incident acute myocardial infarction rates declined on average 2.6% per year (incidence rate ratio 0.974, 95% confidence interval 0.972–0.977) in men and 2.8% per year (incidence rate ratio 0.972, 95% confidence interval 0.971–0.974) in women, contributed by declining rates of hospitalisations (1.8% and 1.9% per year in men and women, respectively) and deaths (6.0% and 5.8% per year in men and women, respectively). Declining rates were observed in all three age groups. The overall acute myocardial infarction incidence rates continued to decline from 2009 onwards, with a steeper decline compared to 2001–2009. During 2009–2014, gender-adjusted acute myocardial infarction incidence among adults age 25–44 years declined 5.3% per year, contributed mostly by declines in hospitalisation rates (5.1% per year). Conclusion Acute myocardial infarction incidence rates continued to decline after 2009 in Norway in both men and women. The decline started to involve individuals aged 25–44 years, marking a turning point in the previously reported stagnation of rates during 2001–2009.


2004 ◽  
Vol 3 (3) ◽  
pp. 61-62
Author(s):  
Y Verma ◽  
CM Singh ◽  
R Gupta ◽  
VK Sharma ◽  
G Singh ◽  
...  

Arrythmias after Acute myocardial infarction (AMI) have a prognostic value, in addition to the morbidity it involves. To evaluate the significance of arrythmias 50 patients of AMI (37-Male, 13-Female) in the age group of 35-72 years were studies, Out of these 50 cases, 48% (n=24) had anterior wall myocardial infarction, 30% (n-15) had inferior wall myocardial infarction, 22% (n=11) had interior+Right Ventricular wall myocardial infarction. Thrombolysis was done in 56% (n=28) patients fulfilling inclusion criteria. Left ventricular ejection fraction (LVEF) of less than 50% was present in 24% (n=12) patients. 50% patients (n=25) experienced “In hospital arrythmias” and 28% (n=7) patients had cardiac events in 6 months follow up. In the group without “In hospital arrythmias" 60% (n-15) developed follow up events. Out of 12 patients with LVEF of less than 50% (n=12), 8 patients (66%) developed “In Hospital arrythmias” and 10 patients (83%) developed subsequent morbid cardiac events.


2020 ◽  
pp. 1-3
Author(s):  
Harita M. Patel ◽  
Hitarth Joshi

BACKGROUND: Incidence of Arrhythmia in first week of Acute myocardial infarction. AIM To study the incidence of arrhythmias in the first week of Acute Myocardial Infarction (AMI) with respect to type of arrhythmia, age distribution, sex and location of infarction, various risk factors in a patient population from western India and to evaluate its prognostic value and relation of complications with incidence of arrhythmias. METHOD : Hundred cases of AMI with arrhythmia admitted in ICCU of G K GENERAL HOSPITAL – GAIMS , BHUJ were taken in the study. RESULT: • Among 100 cases, maximum incidence (40%) was found in 6th decade. Incidence of a rrhythmias was higher in males (81%) than females (19%). Anterior wall infarcts (61%) were more common than inferior wall (36%). Ventricular Premature Contraction (VPC) was the commonest arrhythmia is anterior wall MI (45.9%) and in inferior wall MI (19.4%). CONCLUSION : • Hence, in one of the largest study of this kind in a patient population of Western India, we established VPC’s as the most common arrhythmia in AMI patients. Older patients (sixth decade) and males are affected more commonly. Ventricular tachycardia is more fatal in acute inferior wall MI.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
J A Fuentes Mendoza ◽  
O A Mondaca Garcia ◽  
N G Espinola Zavaleta

Abstract Introduction Cardiac rupture has been one of the most frequent fatal complications of acute myocardial infarction in cases series reported since 1977. However, in exceptional cases, the rupture of the left ventricle is contained by the pericardium and by fibrous tissue, forming a pseudoaneurysm, which is characterized by the absence of myocardial tissue in its wall and a relatively narrow neck between the ventricle and the ventricular chamber. Although there is no estimated time for rupture, it is well established that the risk of rupture is 30 to 40% and mortality up to 10%. Pseudoaneurysm is a rarer entity than rupture and is usually diagnosed incidentally by imaging methods in up to 48% of cases. The most frequent imaging method for their diagnosis is 2D echocardiography, followed by cardiac catheterization and finally cardiac magnetic resonance. The most frequent location of the pseudoaneurysm secondary to acute myocardial infarction is the inferior wall and the posterolateral wall of the left ventricle. Case Report We present 72-year-old male patient with a history of type 2 diabetes and smoking, who started symptoms with sudden onset of oppressive chest pain of 20 minutes duration, he did not attend medical attention. A month later, he went for a valuation with a first-contact physician, who referred him to our institution with a diagnosis of acute myocardial infarction without reperfusion therapy. At the initial assessment, it was found asymptomatic, in the resting ECG was found QS pattern with reversal of the T wave in leads DII, DIII and AVF. Cardiac SPECT was performed and showed an inferior transmural infarction, which extended as non-transmural to the inferolateral and inferoseptal walls, without ischemia. (Img. 1 and 2). A 2D and 3D transthoracic echocardiogram was performed, in which akinesia of the inferoseptal and apical walls was documented, as well as a saccular pseudoaneurysm of 5.6 X 4.7 cm in the basal and middle segment of the inferior and inferolateral walls, with an entrance orifice. 2.6 X 2.4 cm, as well as pericardial effusion. (Fig. 3 and 4). Coronary angiography was performed, demonstrating chronic total occlusion of the right coronary in its proximal segment and ostial obstruction of the left anterior descending. Cardiac magnetic resonance revealed inferior infarction and the presence of a pseudoaneurysm with lamellar thrombus was corroborated. (Img. 5). The patient was taken to surgical treatment, by reconstruction of the left ventricle with the Dor technique and CABG of the right coronary artery and the anterior descending artery. Receives medical treatment and a 1-month follow-up is in class I of the NYHA. Conclusion It is a clinical case about a potentially fatal complication of acute myocardial infarction, which in our case was detected incidentally since the patient had remained asymptomatic, there lies the importance of obtaining an accurate diagnosis in order to impact on the patient survival. Abstract P262 Figure. Pseudoaneurysm multi-modality images


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