scholarly journals Variation spatiotemporelle de la cryptorchidie et de l’hypospadias au Québec : Une étude exploratoire

2013 ◽  
Vol 5 (3) ◽  
pp. 167
Author(s):  
Sophie Guertin ◽  
Karine-Sylvie Lemieux ◽  
Natalie Makhoulian ◽  
Sébastien Michaud ◽  
Rose-Marie Patry ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Congenital Anomalies ◽  
Environmental Contaminants ◽  
Live Births ◽  
Statistical Institute ◽  
Anomalies Congénitales ◽  
Increasing Trend ◽  
Potential Link ◽  
Système De Surveillance

Objectifs : La majorité des études effectuées au cours des dernièresdécennies ont mis en évidence une augmentation du nombre decas de cryptorchidie et d’hypospadias entre 1970 et 1990. De plus,l’importante variabilité géographique de ces anomalies est biendécrite. Cette étude vise à mesurer la prévalence à la naissancede la cryptorchidie et de l’hypospadias au Québec, à vérifier sices anomalies sont en augmentation et à en évaluer la répartitioninterrégionale.Méthode : Une étude épidémiologique descriptive a été réalisée àpartir du nombre de garçons de cinq ans et moins hospitalisés pourune cryptorchidie ou un hypospadias au Québec de 1989 à 2004selon les données du fichier administratif d’hospitalisation MEDÉCHO.Les données sur les naissances provenaient de l’Institut dela statistique du Québec.Résultats : La prévalence annuelle moyenne pour 1000 naissancesvivantes de sexe masculin est de 19,1 (IC à 95 % : 18,8-19,4) pourla cryptorchidie et 11,4 (IC à 95 % 11,1-11,6) pour l’hypospadiasau Québec. Au cours de la période étudiée, la prévalence de cryptorchidiea légèrement diminué, alors que celle de l’hypospadiasest demeurée stable. Comparativement à la province du Québec,des régions présentent une prévalence significativement différentede cryptorchidie et/ou d’hypospadias. .Conclusion : Au Québec, la prévalence de cryptorchidie est enlégère diminution alors que celle de l’hypospadias est stable.Des variations régionales significatives sont observables. D’autresétudes sont nécessaires afin d’évaluer l’hypothèse d’un lien avecles contaminants environnementaux en émergence. L’implantationd’un système de surveillance des anomalies congénitales permettraitune représentation plus valide de la situation.Objectives: Previous research has shown evidence of an increasein the number of cases of cryptorchidism and hypospadias between1970 and 1990. Geographical disparities of these anomalies arewidely described. This study aims to measure the prevalence ofcryptorchidism and hypospadias at birth in the province of Quebec,to investigate if there is an increasing trend and to assess the interregionaldistribution of these anomalies. Method: A descriptive epidemiological study was undertaken toinvestigate the number of newborn males up to five years of age,hospitalized for cryptorchidism or hypospadias in Quebec between1989 and 2004 based on data collected from MED-ECHO, a databasecompiling hospitalizations and used for administrative purposes.Birth rates were provided by the Statistical Institute of Quebec. Results: Mean yearly prevalence per 1000 male live births was19.1 (95% CI 18.8-19.4) for cryptorchidism and 11.4 (95% CI11.1-11.6) for hypospadias for the province of Quebec. Within theperiod of study, the prevalence of cryptorchidism decreased slightlywhile that of hypospadias remained stable. Significant variationsin prevalence were observed in some regions compared to theprovince, for both pathologies. Conclusion: In Quebec, the prevalence of cryptorchidism isdecreasing while that of hypospadias is stable. There is significantregional variation among the province. More studies are neededto assess the potential link with environmental contaminants asan emerging explanation. The implementation of an adequate surveillancesystem for congenital anomalies would allow for a moreaccurate representation of the situation.

scholarly journals Tetralogy of Fallot in infants less than one year old in the Valencia Region (Spain)

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
C Cavero Carbonell ◽  
L Barrachina Bonet ◽  
T Fernández Rojas ◽  
S Moreno Marro ◽  
L Páramo Rodríguez ◽  
...  
Keyword(s):  
Tetralogy Of Fallot ◽  
Congenital Anomalies ◽  
Population Based ◽  
Termination Of Pregnancy ◽  
Fetal Anomaly ◽  
Live Births ◽  
Epidemiologic Surveillance ◽  
Increasing Trend ◽  
The Difference ◽  
One Year

Abstract Background Tetralogy of Fallot (TF) is a rare disease characterized by the presence of 4 congenital heart defects (CHD). Objective: to describe the temporal trend and distribution of the TF in the Valencia Region (VR), in less than one year old, during the period 2007-2016. Methods Live births, stillbirths and termination of pregnancy due to fetal anomaly (TOPFA) between 2007-2016 with TF (code Q21.3 of the ICD10-BPA) were selected from the Congenital Anomalies (CA) population-based Registry of VR. The cases were confirmed through the review of clinical documentation. The prevalence of 10000 births with 95% confidence intervals (95%CI) was calculated for the period and for each year, and a descriptive analysis of sociodemographic and clinical variables was made. Results 146 cases were identified (45.2% male, 31.5% female and 23.3% unknown), 89.0% were simple pregnancies and 54.8% were diagnosed prenatally. The overall prevalence of TF was 3.0/10000 births (95%CI: 2.5-3.5), being 2015 the year with the highest prevalence (4.3/10000 births) and 2011 with the lowest (1.8/10000 births). These changes were mainly due to the increase and decrease in the number of TOPFA respectively. 74.7% were live births, 22.6% TOPFA and 2.7% stillbirths. The prevalence in live births was 2.2/10000 births (95%CI: 1.8-2.6) and in TOPFA it was 0.7/10000 births (95%CI: 0.4-0.9), identifying an increasing trend during the period in the last one. 11.0% of live births died during the first year of life. 45.9% of the cases had another CA associated with the TF, being CHD in 52.7% of cases. 66.4% of the mothers were over 30 years of age, being the most frequent those between 30-34 years (30.1%). Conclusions The prevalence obtained in the VR was lower than that of EUROCAT 3.5/10000 births (95%CI: 3.3-3.6) during the same period. EUROCAT has also identified the difference between the prevalence in live births (2.9 (95%CI: 2.8-3.0)) and TOPFA (0.5 (95%CI: 0.5-0.6)), and the increasing trend in the last one. Key messages The prevalence of Tetralogy of Fallot obtained in the VR was lower than that of EUROCAT (European network of population-based registries for the epidemiologic surveillance of congenital anomalies). EUROCAT has also identified the difference between the prevalence of Tetralogy of Fallot in live births and termination of pregnancy due to fetal anomaly, and the increasing trend in the last one.

Congenital Anomalies Among Singleton Live Births in a Tertiary Care Teaching Hospital

2011 ◽  
Vol 3 (11) ◽  
pp. 358-360
Author(s):  
Manikanta Reddy. V Manikanta Reddy. V ◽  
◽  
Senthil Kumar. S Senthil Kumar. S ◽  
Sanjeeva Reddy. N Sanjeeva Reddy. N
Keyword(s):  
Teaching Hospital ◽  
Congenital Anomalies ◽  
Tertiary Care ◽  
Tertiary Care Teaching Hospital ◽  
Live Births ◽  
Care Teaching

scholarly journals Major congenital anomalies at birth in Benghazi, Libyan Arab Jamahiriya, 1995

2000 ◽  
Vol 6 (1) ◽  
pp. 66-75
Author(s):  
R. Singh ◽  
O. Al Sudani
Keyword(s):  
Risk Factors ◽  
Central Nervous System ◽  
Congenital Anomalies ◽  
Perinatal Death ◽  
Multiple Congenital Anomalies ◽  
Live Births ◽  
Low Birth Weight Babies ◽  
The Central Nervous System ◽  
Associated Risk Factors ◽  
Over 40 Years

A study was conducted to investigate the magnitude, nature and associated risk factors of major congenital anomalies [MCAs]at birth in Benghazi, Libyan Arab Jamahiriya in 1995. The incidence of MCAs was 7.4 per 1000 live births and 9.3 per 1000 total births. The rate was higher in summer, in babies born to mothers over 40 years and low-birth-weight babies or those born preterm or post-term. In 56.1% of cases there were multiple congenital anomalies and > two-thirds of the major congenital anomalies were chromosomal, musculoskeletal or of the central nervous system. The incidence of perinatal death in births with MCAs was 49.1% compared with 2.7% for all births

scholarly journals Sulfonamide Use During the First Trimester of Pregnancy and Risk of Selected Congenital Anomalies Among Live Births

2016 ◽  
Vol 3 (3) ◽  
pp. 202-203
Author(s):  
Craig Hansen ◽  
Susan E Adrade ◽  
Heather Freiman ◽  
Sascha Dublin ◽  
Katie Haffenreffer ◽  
...  
Keyword(s):  
Congenital Anomalies ◽  
First Trimester ◽  
Live Births ◽  
First Trimester Of Pregnancy

Urinary Tract Anomalies in Neonates With Spontaneous Pneumothorax and/or Pneumomediastinum

PEDIATRICS ◽  
1977 ◽  
Vol 59 (6) ◽  
pp. 1048-1049
Author(s):  
Bassam N. Bashour ◽  
J. Williamson Balfe
Keyword(s):  
Urinary Tract ◽  
Congenital Anomalies ◽  
Spontaneous Pneumothorax ◽  
Clinical Population ◽  
Live Births ◽  
Apparent Association ◽  
Urinary Tract Anomalies

Spontaneous pneumothorax is reportedly occurring in 0.05% to 1% of all live births.1,2 Pediatricians have long been aware of the apparent association between spontaneous pneumothorax, with or without pneumomediastinum, and congenital anomalies of the urinary tract. However, reports of the incidence of this relationship have been inconclusive, based on small numbers of infants.3-5 We therefore sought to determine this incidence in a large clinical population. METHODS We reviewed the records of all 6,236 infants admitted to the neonatology unit during 1961-1967 and selected all cases of spontaneous pneumothorax or pneumomediastinum or both (lung rupture) and of congenital urinary tract anomalies.

Down Syndrome

2013 ◽  
Author(s):  
Erica P Lin ◽  
James P Spaeth
Keyword(s):  
Down Syndrome ◽  
General Anesthesia ◽  
Surgical Procedures ◽  
Perioperative Care ◽  
Congenital Anomalies ◽  
Trisomy 21 ◽  
Live Births

Trisomy 21, or Down syndrome, is the most common human chromosomal syndrome, with an overall incidence of 1:700 live births. Because of its association with other congenital anomalies, children with this syndrome often present for surgical procedures that require general anesthesia. Anesthesiologists caring for these patients must be familiar with the implications of Down syndrome on perioperative care.

Complex Congenital Heart Defect, Heterotaxy, Imperforate Anus, and Other Congenital Anomalies in a 27-Week Infant: A Case Study

2014 ◽  
Vol 33 (4) ◽  
pp. 199-203 ◽  
Author(s):  
Angela Koerner
Keyword(s):  
Congenital Anomalies ◽  
Intraventricular Hemorrhage ◽  
Congenital Heart ◽  
Surgical Intervention ◽  
First Year ◽  
Risk Of Infection ◽  
Cardiac Defects ◽  
Live Births ◽  
First Year Of Life

According to multiple researchers and studies, congenital heart disease (CHD) occurs in approximately 4.8–12.0 of 1,000 live births in the general population, and 2.4 per 1,000 cases are serious enough to require surgery or cardiac catheterization in the first year of life.1 Historically, it has been assumed that the earlier the gestational age with CHD, the poorer the outcome; however, with continued improvements in neonatal care, this hypothesis should be looked at more closely. This case illustrates the challenges associated with prematurity, complex cardiac defects, intraventricular hemorrhage (IVH), and other congenital anomalies that increase the risk of infection and/or surgical intervention. It will discuss the hospital course of a twin, born at 27 weeks gestation, who was found to have all of these diagnoses, yet, despite the complexity of his case, he had a predominantly uncomplicated hospital course.

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