Contribution of Lp (a) to the Occurrence of Vascular Diseases : Correlation of Several Risk Factors Including Diabetes Mellitus

Abstract Purpose To analyze the clinical features and related risk factors in diabetic retinopathy (DR) and subclinical atherosclerosis, the micro- and macro-vascular diseases in newly diagnosed type 2 diabetes mellitus (T2DM). Methods A retrospective study of 435 cases of inpatients with newly diagnosed T2DM from 2013–2017, and compare the 2 types of T2DM related vascular complications. Results The macro- and microvascular complications are not rare at this stage. Subclinical atherosclerosis was found in 251 subjects (57.7%), which was higher than that of DR (13.1%). In addition, some cases of subclinical atherosclerosis co-existed with DR, suggesting that DR was related with subclinical atherosclerosis (r=0.098, P=0.041). Older age showed a significant association with both subclinical atherosclerosis and DR. Single factor analysis indicated that dyslipidemia was the common risk factor in DR and subclinical atherosclerosis. Conclusions It should be paid attention to the screening of both DR and subclinical atherosclerosis in each age group of newly diagnosed T2DM. Except for the control of blood glucose, the control of the dyslipidemia is important in the prevention and treatment of the micro- and macro-vascular diseases.

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Trends in vascular risk factors and medication use in patients with various manifestations of vascular diseases or type 2 diabetes mellitus from 1996 to 2007: the Second Manifestations of ARTerial disease study

European Journal of Cardiovascular Prevention & Rehabilitation ◽

10.1097/hjr.0b013e328336a0f8 ◽

2010 ◽

Vol 17 (6) ◽

pp. 628-636 ◽

Cited By ~ 9

Author(s):

Anne Vlek ◽

Frank Visseren ◽

Ale Algra ◽

Sabita Soedamah-Muthu ◽

Frans Moll ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Medication Use ◽

Vascular Diseases ◽

Arterial Disease ◽

Vascular Risk ◽

Disease Study

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Anticoagulation ant antiplatеlet therapy in patients with COVID-19 infection

Bulgarian Cardiology ◽

10.3897/bgcardio.27.e64222 ◽

2021 ◽

Vol 27 (3) ◽

pp. 24-29

Author(s):

Zheyna Cherneva ◽

Radostina Cherneva

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Endothelial Dysfunction ◽

Distress Syndrome ◽

Clinical Course ◽

Anticoagulation Therapy ◽

Vascular Diseases ◽

Cytokine Storm ◽

Thrombotic Complications ◽

Cardio Vascular

COVID-19 infection is characterized with hyperstimulated inﬂ ammatory response that affects lungs, cytokine storm and acute respiratory distress syndrome. Thrombotic complications are the leading reason for death in COVID-19 patients. Those of them with previous cardio-vascular diseases or risk factors – obesity, arterial hypertension, diabetes mellitus, advanced age are with higher risk for worse clinical outcome. Coagulopathy as well as thrombocytopathy and endothelial dysfunction are signiﬁ cant pathophysiological factors for the severe clinical course of the infection. Beside anticoagulation therapy, targetеd strategies regarding thrombocytopathy and endothelial dysfunction are necessary for the treatment of patients with COVID-19 infection.

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Metabolic syndrome as a prothrombogenic state

Obesity and metabolism ◽

10.14341/2071-8713-5239 ◽

2009 ◽

Vol 6 (3) ◽

pp. 3-9

Author(s):

M A Berkovskaya ◽

S A Butrova

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Type 2 Diabetes ◽

Metabolic Syndrome ◽

Type 2 Diabetes Mellitus ◽

Scientific Knowledge ◽

Vascular Diseases ◽

Prevalence Of Obesity ◽

Cardio Vascular

The prevalence of obesity has reached epidemic proportions nowadays. Abdominal obesity is the most unfavorable one, because of its association with the complex of markers and risk factors ofcardiovascular diseases and type 2 diabetes mellitus, which is called metabolic syndrome (MS). MS also increases risk of atherothrombosis because it is characterized by low fibrinolysis and prothrombogenic changes in coagulation and platelet hemostasis. The review highlights the mechanisms of hemostatic disturbances in MS, which eхends our scientific knowledge about pathogenesis of cardio vascular diseases

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