To Validate The Use Of Trans Vaginal Sonography – A Non Invasive Tool As A Screening Method For Patients With Postmenopausal Bleeding

10.5580/2be3 ◽  
2012 ◽  
Vol 16 (2) ◽  
Keyword(s):  
Screening Method ◽  
Postmenopausal Bleeding ◽  
Non Invasive ◽  
Vaginal Sonography

A STUDY OF ENDOMETRIAL THICKNESS IN TRANS VAGINAL SONOGRAPHY IN RELATION WITH HISTOPATHOLOGY REPORT IN DILATION & CURRATAGE IN AUB WOMEN

2019 ◽  
pp. 1-2
Keyword(s):  
Comparative Study ◽  
Endometrial Thickness ◽  
P Value ◽  
First Line ◽  
Non Invasive ◽  
Dilation And Curettage ◽  
Study Results ◽  
Vaginal Sonography ◽  
In Trans

A study of of endometrial thickness on TVS in relation with histopathology report on dilation and curettage. AIM AND OBJECTIVE-To set a cut off limit of endometrial thickness on TVS for differtiating between normal and abnormal endometrium. MATERIAL AND METHOD-hospital based comparative study. RESULTS-TVS is non invasive ,simple first line procedure in AUB women. Mean endometrial thickness in normal endometrial group was 8.00±2.44 mm and in abnormal endometrial group was 15.16±33 mm.The difference was found highly significant (p value<.001)

A new accurate and non-invasive screening method for renovascular hypertension

1988 ◽  
Vol 6 (4) ◽  
pp. S458-460 ◽  
Author(s):  
Nobuo Handa ◽  
Ryuzo Fukanaga ◽  
Satoshi Ogawa ◽  
Masayasu Matsumoto ◽  
Kazufumi Kimura ◽  
...  
Keyword(s):  
Renovascular Hypertension ◽  
Screening Method ◽  
Non Invasive

The Continuing Development of Vibration Arthrometry as a Screening Method in Developmental Dysplasia of the Hip

1994 ◽  
Vol 4 (1) ◽  
pp. 41-49
Author(s):  
W. G. Kernohan ◽  
B. Trainor ◽  
P. Haugh ◽  
A. Johnston ◽  
I. Turner ◽  
...  
Keyword(s):  
Screening Method ◽  
Clinical Signs ◽  
Developmental Dysplasia ◽  
Non Invasive ◽  
Experienced Nurse ◽  
Diagnostic Modalities ◽  
Paediatric Orthopaedic ◽  
Further Development ◽  
Dysplasia Of The Hip ◽  
Vibration Arthrometry

As part of the continuing development of a non-invasive, objective screening method to achieve efficient early detection of developmental dysplasia of the hip (DDH), we determined the diagnostic sensitivity of an experienced nurse examiner and vibration arthrometry in the range of pathological anatomy of the disease. A cohort of 25 children were studied prior to commencement of their treatment. The hips were classified into four categories by an experienced paediatric orthopaedic surgeon with all diagnostic modalities available (“normal”, “stable but dysplastic”, “unstable and reducible” or “irreducible”). Of the 28 hips identified as abnormal, two hips were classified as stabledysplastic, 11 were unstable/reducible and 15 were irreducible hips. The experienced nurse examiner identified eight out of 11 unstable-reducible hips and reported clinical signs of abnormality in another 18 cases. Vibration arthrometry identified nine out of 11 unstable-reducible dislocations and detected abnormal signals from three irreducible hips. Vibration arthrometry may be of value in detecting abnormality in unstable-reducible and clicking hips. The low detection rate in the irreducible and dysplastic hips by vibration arthrometry was due to the absence of detectable vibration from mechanical events as the hips were manoeuvred. Examination by an experienced clinical examiner continues to be necessary if all degrees of mechanical abnormality in DDH are to be detected. Further development is required to achieve an objective non-invasive system of detecting all stages in the pathology of DDH.

Circulating tumor cell count from a blood sample for colorectal cancer (CRC) prevention: A 627-patient prospective study.

2019 ◽  
Vol 37 (4_suppl) ◽  
pp. 485-485 ◽  
Author(s):  
Wen-Sy Tsai ◽  
Drew Watson ◽  
Ying Chang ◽  
Ben Hsieh ◽  
Hung-Jen Shao ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Logistic Regression ◽  
Prospective Study ◽  
Compliance Rate ◽  
Screening Method ◽  
Unmet Need ◽  
Detection Methods ◽  
P Value ◽  
Non Invasive ◽  
Adenoma Detection

485 Background: Up to 25% of patients with adenomas progress to having colorectal cancer. If detected early, adenomas can be removed with a diagnostic colonoscopy procedure, preventing cancer. Invasive colonoscopy is the only screening method with the sensitivity to accurately detect adenomas, but has a low compliance rate of 38% for screening. Available non-invasive tests (including stool-based multi-analyte tests) have very limited sensitivity for adenomas. Hence, there is an unmet need for a non-invasive test for adenoma detection. Methods: IRB-approved prospective study was conducted in 627 subjects 50 years or older- recommended for routine CRC screening- 405 subjects had adenoma or CRC, confirmed by colonoscopy with tumor biopsy. Two mL peripheral blood was processed using the CellMax biomimetic platform (CMx), which uses a microfluidic biochip to enumerate circulating tumor cells (CTCs). Nominal logistic regression was used to assess performance while proportional odds logistic regression and Cuzick’s trend test were used to determine association of CTC counts with cancer stage. Results: An increase in CTC count was significantly correlated with an increase in disease burden (Cuzick’s Test p-value < 0.0001). Furthermore, there was a significant association between CTC counts and stages of adenoma-carcinoma progression (Likelihood ratio p-value < 0.0001). The CTC enumeration was able to differentiate between healthy and diseased patients (adenoma + cancer). Conclusions: To the best of our knowledge, these are the first reported results for a blood test that has high accuracy for adenoma detection, and truly enables colorectal cancer prevention. This test can be administered in the primary care setting and drive high compliance.[Table: see text]

scholarly journals Screening method for diagnosis of pharyngolaryngeal reflux

2021 ◽  
Vol 23 (3) ◽  
pp. 236-239
Author(s):  
Marina A. Ryabova ◽  
◽  
Natalia A. Shumilova ◽  
Liubov V. Georgieva ◽  
Artem V. Tishkov ◽  
...  
Keyword(s):  
Roc Analysis ◽  
Ph Monitoring ◽  
Screening Method ◽  
Control Group ◽  
Study Group ◽  
Upper Respiratory Tract ◽  
Non Invasive ◽  
Patient Complaints ◽  
Invasive Method ◽  
Upper Respiratory

Pharyngolaryngeal reflux (PLR) can cause the upper respiratory tract pathology. To diagnose PLR based on complaints is rather difficult, due to the absence of typical manifestations of reflux syndrome in some cases of the disease. The use of daily impedance pH monitoring of the esophagus is not always possible due to the invasiveness and unavailability of the method. The aim of the study was to develop an affordable non-invasive method for diagnosing PLR. The study group consisted of 48 patients with PLR proven by the results of impedance pH-monitoring. The control group consisted of 20 healthy patients. The “Pharyngolaryngeal reflux index” questionnaire was developed based on the analysis of patient complaints. The questionnaire was assessed using ROC analysis. Patients who scored 5.5 points according to the results of the questionnaire with a probability of 93.2% have PLR. Thus, a method for the diagnosis of PLR has been developed, including the simultaneous comparison of the laryngoscopic signs of PLR with the highest diagnostic sensitivity (hyperemia, edema, maceration of the interarytenoid mucosa) and “Pharyngolaryngeal reflux index” questionnaire results, which allows diagnosing of PLR.

scholarly journals A STUDY OF ENDOMETRIAL THICKNESS IN TRANS VAGINAL SONOGRAPHY IN RELATION WITH HISTOPATHOLOGY REPORT IN DILATION & CURRATAGE IN AUB WOMEN

2019 ◽  
pp. 1-2
Author(s):  
Mool Chand Khichar ◽  
Bajarang Lal Rar
Keyword(s):  
Comparative Study ◽  
Endometrial Thickness ◽  
P Value ◽  
First Line ◽  
Non Invasive ◽  
Dilation And Curettage ◽  
Study Results ◽  
Vaginal Sonography ◽  
In Trans

A study of of endometrial thickness on TVS in relation with histopathology report on dilation and curettage. AIM AND OBJECTIVE-To set a cut off limit of endometrial thickness on TVS for differtiating between normal and abnormal endometrium. MATERIAL AND METHOD-hospital based comparative study. RESULTS-TVS is non invasive ,simple first line procedure in AUB women. Mean endometrial thickness in normal endometrial group was 8.00±2.44 mm and in abnormal endometrial group was 15.16±33 mm.The difference was found highly significant (p value<.001)

scholarly journals Sepsis-Associated Brain Dysfunction: A Review of Current Literature

2020 ◽  
Vol 17 (16) ◽  
pp. 5852
Author(s):  
Piotr F. Czempik ◽  
Michał P. Pluta ◽  
Łukasz J. Krzych
Keyword(s):  
Imaging Techniques ◽  
Screening Method ◽  
Specific Treatment ◽  
Brain Dysfunction ◽  
Non Invasive ◽  
Clinical Neurological Examination ◽  
Electrographic Seizures ◽  
The Moment ◽  
And Function ◽  
The Brain

Sepsis-associated brain dysfunction (SABD) may be the most common type of encephalopathy in critically ill patients. SABD develops in up to 70% of septic patients and represents the most frequent organ insufficiency associated with sepsis. It presents with a plethora of acute neurological features and may have several serious long-term psychiatric consequences. SABD might cause various pathological changes in the brain through numerous mechanisms. Clinical neurological examination is the basic screening method for SABD, although it may be challenging in subjects receiving with opioids and sedative agents. As electrographic seizures and periodic discharges might be present in 20% of septic patients, screening with electroencephalography (EEG) might be useful. Several imaging techniques have been suggested for non-invasive assessment of structure and function of the brain in SABD patients; however, their usefulness is rather limited. Although several experimental therapies have been postulated, at the moment, no specific treatment exists. Clinicians should focus on preventive measures and optimal management of sepsis. This review discusses epidemiology, clinical presentation, pathology, pathophysiology, diagnosis, management, and prevention of SABD.

scholarly journals Performance of a MethyLight assay for methylated SFRP2 DNA detection in colorectal cancer tissue and serum

2019 ◽  
Vol 34 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Hui Li ◽  
Zhenzhen Wang ◽  
Guodong Zhao ◽  
Yong Ma ◽  
Ying Chen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Colorectal Cancer Screening ◽  
Limit Of Detection ◽  
Methylation Status ◽  
Screening Method ◽  
Cancer Tissue ◽  
Non Invasive ◽  
Cancer Tissues ◽  
Methylight Assay

Background: Colorectal cancer is one of the five most common cancers in China, and its incidence is steadily increasing. An accurate and non-invasive screening method is needed to increase the population uptake of colorectal cancer screening. Secreted frizzled-related protein 2 ( SFRP2) has been found to be hypermethylated in most colorectal cancer patients, and it may fulfill the role of a non-invasive biomarker for colorectal cancer screening. Methods: Methylation status of SFRP2 was examined in 17 cancer tissues and paired adjacent paracancer tissues by a new SFRP2 MethyLight assay, which was also used to test the serum of 62 patients with colorectal cancer and 55 normal individuals. Results: The limit of detection of the SFRP2 MethyLight assay was about 200 pg per reaction. The SFRP2 methylation level was higher in 94.1% colorectal cancer tissues than in paired adjacent paracancer tissues ( P<0.001). The sensitivity and specificity of SFRP2 for detecting colorectal cancer in serum were 69.4% (95% confidence interval (CI) 56.2, 80.1%) and 87.3% (95% CI 74.9, 94.3%), respectively. Conclusion: SFRP2 methylation in serum has the potential to be a non-invasive biomarker for colorectal cancer screening.

The sensitivity and specificity of vaginal sonography in detecting endometrial abnormalities in women with postmenopausal bleeding

1996 ◽  
Vol 24 (2) ◽  
pp. 79-82 ◽  
Author(s):  
Igal Wolman ◽  
Joseph Sagi ◽  
Shimon Ginat ◽  
Ariel J. Jaffa ◽  
Joseph Hartoov ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Postmenopausal Bleeding ◽  
Vaginal Sonography
Sign in / Sign up

Export Citation Format

Share Document