Learning from ICH Q6B: Quality Control Ideas to Improve the Quality Standards of Chinese Herbal Slices

2019 ◽  
Vol 102 (3) ◽  
pp. 695-698
Author(s):  
Jieli Mo ◽  
Hainan Wang ◽  
Bo Yuan
Keyword(s):  
Quality Control ◽  
Quality Standards ◽  
Quality Standard ◽  
Standard System ◽  
International Conference ◽  
Biotechnological Products ◽  
Chinese Herbal

Abstract Learning from the ideas of the International Conference on Harmonization Q6B guideline in the quality control of biological and biotechnological products, it is proposed to improve the quality standard system and quality control of Chinese herbal slices, from reforming the mechanism of setting standards, improving the principles of quality standards, and clarifying the basis for setting the standards. The quality standard and quality control of Chinese herbal slices need to be improved through practical strategies with reasonable technology.

The Quality Standards Study of Hedyotis Diffusa

2014 ◽  
Vol 955-959 ◽  
pp. 826-829
Author(s):  
Yu Lian Xu ◽  
Song Xiang ◽  
Pu Guo ◽  
Lin Niu ◽  
Yun Lan Li ◽  
...  
Keyword(s):  
Quality Control ◽  
Thin Layer ◽  
Quality Standards ◽  
Quality Standard ◽  
Control Methods ◽  
Coumaric Acid ◽  
Content Determination ◽  
Hedyotis Diffusa

The research provided the reliable quality control methods for Hedyotis diffusa Willd, including identification (thin-layer identification), inspection (moisture, ash and extraction) and content determination. In thin-layer identification, samples showed same color spot as standard Hedyotis diffusa in same location; The moisture, ash, acid-insoluble ash and extraction of herb were respectively 5.9%~8.2%, 7.4%~13.4%, 1.2%~6.4% and 5.6%~11.7%. So we suggested that the moisture should lower than 13.0%, the ash should lower than 15.0% and the acid-insoluble ash should lower than 9.0% and the extraction should more than 5.0%. The content determination of p-coumaric acid ranges from 0.08 to 0.17 (%, g/g) and the suggested p-coumaric acid on the dried should not less than 0.06%. The suggestion could provide the reference to establish the quality standard of Hedyotis diffusa Willd.

Quality Control in the Production of Forest Planting Stock

1983 ◽  
Vol 59 (3) ◽  
pp. 132-138 ◽  
Author(s):  
A. N. Burdett
Keyword(s):  
Quality Control ◽  
Control System ◽  
Quality Standards ◽  
Quality Standard ◽  
Quality Control System ◽  
Sources Of Information ◽  
Phenotypic Characteristics ◽  
Stock Quality ◽  
Handling Practices ◽  
Definition Of

Plantation performance depends on the outcome of an interaction between the stock planted and its environment. Immediately after planting, it is the degree to which stock is pre-adapted to site conditions (i.e., its phenotype), rather than its genetic potential for adaptation to environment (i.e., its genotype) which has the greatest influence on performance. The purpose of a stock quality control system is to ensure that stock has phenotypic characteristics which adapt it to the planting site. Thus a prerequisite to the creation of an effective quality control system is the definition of stock quality standards which specify the phenotypic characteristics of stock adapted to the conditions of normal use. Physiological principles provide a basis for such standards but they must be refined through trial and error. Thus feedback on the performance of stock conforming to current standards is one key to the development of appropriate stock quality standards. Another is research to determine the causes of unsatisfactory performance. With these sources of information it is possible to modify stock standards or site treatments in a way that improves the cost-effectiveness of regeneration efforts. Culling, the traditional method of quality control, can reduce stock heterogenity, but it cannot transform poor stock into good. Often, therefore, the attainment of a desired quality standard requires an overall improvement in the quality of nursery output. The only practical way of doing this is to modify the nursery environment including cultural and handling practices.

Perbaikan Kualitas Produk Batu Bata Merah Dengan Metode Six Sigma-Dmaic (Studi Kasus Cv. Ghatan Fatahillah Karawang)

UNISTEK ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 6-10
Author(s):  
Egar Naufal Ari Satya ◽  
Wahyudin Wahyudin
Keyword(s):  
Quality Control ◽  
Customer Satisfaction ◽  
Six Sigma ◽  
Quality Standards ◽  
Research Results ◽  
Machine Performance ◽  
Fishbone Diagram ◽  
And Control ◽  
Dmaic Method

Abstrak. Dunia industri yang semakin berkembang akan mengakibatkan banyaknya persaingan. Perus-ahaan yang dapat bersaing adalah perusahaan yang dapat menjaga  kualitas produknya dengan baik sehingga dapat memenuhi kepuasan konsumen. Maka dari itu diperlukan pengendalian kualitas. Penelitian ini difokuskan pada penurunan cacat pada produk batu bata merah di CV. Ghatan Fatahillah dengan metode Six Sigma-DMAIC (Define, Measure, Analyze, Improve, dan Control). Dari hasil penelitian didapatkan DPMO sebesar 36.212 dengan nilai sigma 3,29. Jenis cacat yang paling sering terjadi pada batu bata merah yaitu pecah/patah yaitu sebesar 4.327 atau 59,81% dari total keseluruhan produk yang cacat.  Hasil dari tahap analyze dengan fishbone diagram, ditetapkan penyebab dari pecah/cacat, yaitu: pekerja kurang paham standar kualitas, tidak adanya pemeriksaan produk, pekerja kurang paham prosedur kerja, kinerja mesin tidak stabil, pekerja kurang teliti,  jumlah penggilingan tidak menentu, dan komposisi batu bata tidak menentu. Maka perlu dilakukan usulan perbaikan agar dapat mengurangi jumlah produk yang cacat pada batu bata merah. Kata kunci: DMAIC, DPMO, Pengendalian Kualitas, Six Sigma Abstract. The growing industrial world will result in a lot of competition. Companies that can compete are companies that can maintain the quality of their products well so that they can meet customer satisfaction. Therefore, quality control is needed. This research is focused on reducing defects in red brick products at CV. Ghatan Fatahillah with the Six Sigma-DMAIC method (Define, Measure, Analyze, Improve, and Control). From the research results obtained DPMO of 36,212 with a sigma value of 3.29. The type of defect that most often occurs in red bricks is broken / broken, which is 4,327 or 59.81% of the total defective products. The results of the Analyze stage with the fishbone diagram showed that the causes of breakage / defects were determined, namely: workers do not understand quality standards, lack of product inspection, workers do not understand work procedures, unstable machine performance, workers are not careful, the number of mills is erratic, and composition erratic bricks. So it is necessary to make improvement proposals in order to reduce the number of defective products in red bricks. Keywords: DMAIC, DPMO, Quality Control, Six Sigma

scholarly journals Analisis pengaruh V/C ratio lalu lintas kendaraan terhadap tingkat polusi udara berdasarkan volume lalu lintas kendaraan (studi di kawasan persimpangan Mall SKA Kota Pekanbaru)

Jurnal Zona ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 64-74
Author(s):  
Muhammad Yevizal ◽  
Aras Mulyadi ◽  
Ferry Fatnanta
Keyword(s):  
Quality Standards ◽  
Quality Standard ◽  
Observation Point ◽  
Pollutant Emissions ◽  
Noise Levels ◽  
The Road ◽  
Road Users ◽  
Bus Lane ◽  
On The Road ◽  
The City

Completion of the transportation problems in the city of Pekanbaru currently only looked at in terms of congestion, but not touching insights from environmental aspects such as performance air pollution and noise levels. This research was conducted at the observation point road ahead Repair Tambusai lord Eastern Daihatshu, road Tuanku Tambusai West Side Mall SKA, North Soekarno Hatta street front retail outlets, street front Soekarno Hatta South Hotel Ibis Pekanbaru. V / C Ratio highest in the afternoon rush hour on the road ahead Tambusai lord Stations Daihatsu ie 0.86 pelyanan road performance E. Quality Standard ambient NOx emissions do not exceed the threshold of ambient quality standards, the NOx emission = 281.76 mg/m3. Quality Standard ambient CO emissions do not exceed the threshold of ambient quality standards, namely emission = 7456.79 mg/m3, the noise level over the limit of noise that is 71.41 dB (A). To balance the load reduction in pollutant emissions and noise levels at the flyover plan with the plan of special bus lane traffic volume assumptions have to move 25% of the transfer of the road users of private vehicles and motorbikes switch to using mass public transport vehicles ie Trans Metro bus Pekanbaru.

scholarly journals Design of System for Determining Corn Seed Color Quality Standards using the Fuzzy Logic Method through the Localhost Network

2019 ◽  
Vol 8 (1) ◽  
pp. 62-70
Author(s):  
Reksa Nirvana Alam
Keyword(s):  
Fuzzy Logic ◽  
Seed Quality ◽  
Large Diameter ◽  
Quality Standards ◽  
Quality Standard ◽  
Seed Color ◽  
Accuracy Rate ◽  
Corn Seed ◽  
Color Sensor ◽  
Color Sensors

Control of quality standards is very important role in ensuring corn on the market. Corn seed quality standards are determined from the results of  classification process applied. So far, evaluation process of classification of corn seeds quality is still done manually which takes a long time and the quality of product is'nt evenly distributed. So, we need a tool to determine corn seeds quality to improve its quality. This study conducted color readings of corn seeds using  TCS230 color sensors and sorting  diameter of corn seeds using a small, medium, and large diameter sieve machine. The method for classifying quality standard of corn seed color uses fuzzy logic. The test was carried out by taking data from 3 TCS230 color sensors on each diameter of the sieve machine for corn seeds types used are BISI-2 and BIMA-19. The sensor accuracy is known by comparing data from sensor with data from Color Grab application. The reading results of BISI-2 on the color sensor-1 shows an accuracy rate of 0.3%, the color sensor-2 shows an accuracy rate of 0.72%, and the color sensor-3 shows an accuracy rate of 1.76%. For BIMA-19 corn seeds, the reading on color sensor-1 shows an accuracy of 1.11%, the color sensor-2 shows an accuracy of 24.6%, the color sensor-3 shows an accuracy of 1.10%. The results of fuzzy testing on BISI-2 and BIMA-19 showed that quality standard of maize seeds was good at medium and large diameters, while those on small diameters showed poor quality standards.

Analysis of Chemical Properties and Heavy Metals from Cisadane River, Tangerang, Indonesia

2021 ◽  
Vol 18 (1) ◽  
pp. 81-87
Author(s):  
Desy Rosarina ◽  
Ellysa Kusuma Laksanawati ◽  
Dewi Rosanti
Keyword(s):  
Heavy Metals ◽  
Water Quality ◽  
Chemical Properties ◽  
Data Retrieval ◽  
Quality Standards ◽  
Class Ii ◽  
Quality Standard ◽  
Water Quality Standards ◽  
Water Quality Standard ◽  
A Value

This paper explained heavy metals and chemical properties from the Cisadane River in Tangerang City. A survey method was used to determine the place for sampling the test material. Water measurement is carried out in situ and laboratory tests. Data retrieval was done by purposive sampling determining three observation stations, namely in the Taman Gajah Tunggal park area (station1), Babakan Cikokol residential area (station 2), and Karawaci paper mill area (station 3). The analysis was carried out exactly using analysis. Namely, analysis carried out in the laboratory. The parameters observed were COD, phosphate, DO, BOD, pH. Results of this study informed the water quality in the Cisadane City river did not meet Class II Water Quality Standards based on Government Regulation Number 82, the year 2001. The COD content only meets class II water quality standards at stations 1 and 3. BOD and phosphate content is high and exceeds class II water quality standards. Heavy metal content still meets the water quality standard threshold with a value of Cd less than 0.01 mg/L, Cu less than 0.02 mg/L, Pb less than 0.03mg/L, and Cr less than 0.05mg/L. Zn content exceeds the water quality standard threshold at station three and meets water quality standards at stations 1 and 2 with a value of less than 0.05mg/L.

scholarly journals Effects of Air Pollution on Human Health and Costs: Current Situation in São Paulo, Brazil

2020 ◽  
Vol 12 (12) ◽  
pp. 4875 ◽  
Author(s):  
José Carlos Curvelo Santana ◽  
Amanda Carvalho Miranda ◽  
Charles Lincoln Kenji Yamamura ◽  
Silvério Catureba da Silva Filho ◽  
Elias Basile Tambourgi ◽  
...  
Keyword(s):  
Air Quality ◽  
Respiratory Diseases ◽  
Hospital Costs ◽  
Quality Standards ◽  
Quality Standard ◽  
Sao Paulo ◽  
Pollutant Emissions ◽  
São Paulo ◽  
Positive Correlation ◽  
Diesel Vehicles

This study focused on verifying whether the emission of air pollutants in São Paulo increases the costs and number of hospitalizations for respiratory diseases in Brazil. Data on pollutant emissions, hospitalizations, and hospital costs were collected from 2008 to 2017 and correlated with air quality standards. The results showed that the concentration of particulate matter increased each year during the study period and was highly correlated with hospitalizations due to respiratory diseases. Ozone (O3) was within the quality standard throughout the study period but registered an increase in the mean and a positive correlation with hospitalizations due to respiratory diseases. The carbon monoxide (CO), sulfur dioxide (SO2), and nitrogen dioxide (NO2) levels were within the quality standards throughout the study period with a decrease in the last years studied, but showed a positive correlation with hospitalizations due to respiratory diseases. The pollutant emissions and hospitalizations due to respiratory diseases had an inverse relationship with the monthly rainfall curve for São Paulo, which indicates that rainfall tended to reduce pollutant emissions and consequently hospitalizations due to inhalation of these pollutants. Because costs are directly associated with hospitalizations, both increased during the study period—302,000 hospitalizations at an average cost of 368 USD resulted in a total cost of 111 million USD. To reduce these costs, Brazil should implement stricter policies to improve the air quality of its major cities and develop a viable alternative to diesel vehicles.

scholarly journals A Complex Network Method in Criticality Evaluation of Air Quality Standards

2019 ◽  
Vol 11 (14) ◽  
pp. 3920 ◽  
Author(s):  
Yongchang Wei ◽  
Lei Chen ◽  
Yu Qi ◽  
Can Wang ◽  
Fei Li ◽  
...  
Keyword(s):  
Air Quality ◽  
Complex Network ◽  
Technological Development ◽  
Citation Network ◽  
Quality Standards ◽  
Quality Standard ◽  
Entropy Weight ◽  
Air Quality Standards ◽  
Structural Problems ◽  
Network Method

In recent years, poor air quality has brought serious threats to public health and sustainable development. The air quality standard is an effective prerequisite to ensure the quality of the air. The citation relationships between air quality standards at a certain time point, which reflect technological development and knowledge transition, form a complex network. In this study, an integrated multi-criteria decision making method is proposed to measure the criticality of standards based on a dynamic citation network model. In particular, the Entropy Weight (EW) method is used to set the weights of each node measurement to avoid subjectiveness, while the TOPSIS method is employed to measure the criticality for each air quality standard. A case study based on the data of 444 of China’s national air quality standards reveals that the complex network method facilitates the identification of critical standards effectively. In addition, we found that there exist some structural problems in China’s air quality standard system: the connectivity between standards is insufficient; critical standards are lacking; and the critical standards change over time following the issue of national policies. Finally, policy suggestions are recommended on strengthening inter-standard citation, attaching importance to the revision of critical standards, and the dynamics of critical standards.

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