scholarly journals Hyperparathyroidism in Hemodialyzed Patients – Relation to Melatonin and Reproductive Hormones Before and After Parathyroidectomy

10.5772/30800 ◽  
2012 ◽  
Author(s):  
Radmila Kancheva ◽  
Ivana Zofkova ◽  
Martin Hill ◽  
Sylvie Dusilova-Sulkova ◽  
Ludmila Kancheva ◽  
...  
Keyword(s):  
Reproductive Hormones ◽  
Before And After

Leuprolide acetate affects intestinal motility in female rats before and after ovariectomy

1992 ◽  
Vol 262 (1) ◽  
pp. G185-G190
Author(s):  
R. Khanna ◽  
R. M. Browne ◽  
A. D. Heiner ◽  
M. H. Clench ◽  
J. R. Mathias
Keyword(s):  
Gastrointestinal Motility ◽  
Low Dose ◽  
Reproductive Hormones ◽  
Leuprolide Acetate ◽  
Female Rats ◽  
Ovariectomized Rats ◽  
Gnrh Analogue ◽  
Fed State ◽  
Before And After ◽  
Intact Rats

Leuprolide acetate, a gonadotropin-releasing hormone (GnRH) analogue, is currently being proposed to control debilitating symptoms in women with functional bowel disease. Whether leuprolide alters gastrointestinal motility as part of its actions is unknown. This study was designed to assess, using myoelectric techniques in an animal model, the effects of leuprolide on potential mechanisms of neuromuscular function of small intestine. Female rats with (n = 6) or without (n = 8) bilateral ovariectomy were used to study jejunal motility before and after leuprolide therapy. Throughout the study, daily leuprolide dosages of 0.02, 0.2, or 0.4 micrograms/kg were injected into intact rats and 0.02, 0.2, 0.4, 1.0, or 2.5 micrograms/kg into ovariectomized rats. Recordings were made while the rats were fasted and postprandial and before and after leuprolide administration. Under control conditions, migrating myoelectric complexes (MMCs) were found in intact female rats, whether fasted or postprandial. After ovariectomy, postprandial controls and those treated with low-dose leuprolide (0.02, 0.2, and 0.4 micrograms) had typical fed-state patterns and no MMCs, but at 1.0 and 2.5 micrograms the fed state was inhibited and cycling MMCs occurred at a frequency similar to that of fasted controls. Reproductive hormones thus have a significant effect on gastrointestinal motility.

scholarly journals Clinical and Metabolic Effects of Alpha-Lipoic Acid Associated with Two Different Doses of Myo-Inositol in Women with Polycystic Ovary Syndrome

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Franca Fruzzetti ◽  
Elena Benelli ◽  
Tiziana Fidecicchi ◽  
Massimo Tonacchera
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Lipoic Acid ◽  
Polycystic Ovary ◽  
Insulin Response ◽  
Reproductive Hormones ◽  
Metabolic Effects ◽  
Metabolic Phenotype ◽  
Ovary Syndrome ◽  
Before And After ◽  
Different Doses

The aim of this retrospective study was to evaluate the effects of a treatment with α-lipoic acid (ALA) associated with two different doses of myo-inositol (MI) on clinical and metabolic features of women with polycystic ovary syndrome (PCOS). Eighty-eight women received the treatment, and 71 among them had complete clinical charts and were considered eligible for this study. All women were treated with 800 mg of ALA per day: 43 patients received 2000 mg of MI and 28 received 1000 mg of MI per day. Menstrual cyclicity, BMI, FSH, LH, estradiol, testosterone, androstenedione, fasting insulin, HOMA-IR, and insulin response to a 2 h OGTT were evaluated before and after 6 months of treatment. The presence of diabetic relatives (DRs) was investigated. Cycle regularity was improved in 71.2% of women. The improvement of menstrual cyclicity occurred regardless of the state of IR and the presence of DRs of the patients. Women with IR mainly showed a significant improvement of metabolic parameters, while those without IR had significant changes of reproductive hormones. Patients with DRs did not show significant changes after the treatment. 85.7% of women taking 2000 mg of MI reported a higher improvement of menstrual regularity than those taking 1000 mg of MI (50%; p<0.01). In conclusion, ALA + MI positively affects the menstrual regularity of women with PCOS, regardless of their metabolic phenotype, with a more evident effect with a higher dose of MI. This effect seems to be insulin independent. The presence of IR seems to be a predictor of responsivity to the treatment in terms of an improvement of the metabolic profile.

Heat acclimation and physical training adaptations of young women using different contraceptive hormones

2005 ◽  
Vol 288 (5) ◽  
pp. E868-E875 ◽  
Author(s):  
Lawrence E. Armstrong ◽  
Carl M. Maresh ◽  
NiCole R. Keith ◽  
Tabatha A. Elliott ◽  
Jaci L. VanHeest ◽  
...  
Keyword(s):  
Body Composition ◽  
Steroid Hormones ◽  
Physical Training ◽  
Heat Acclimation ◽  
Reproductive Hormones ◽  
Muscular Endurance ◽  
Training Adaptations ◽  
Physiological Processes ◽  
Significant Difference ◽  
Before And After

Although endogenous and exogenous steroid hormones affect numerous physiological processes, the interactions of reproductive hormones, chronic exercise training, and heat acclimation are unknown. This investigation evaluated the responses and adaptations of 36 inactive females [age 21 ± 3 (SD) yr] as they undertook a 7- to 8-wk program [heat acclimation and physical training (HAPT)] of indoor heat acclimation (90 min/day, 3 days/wk) and outdoor physical training (3 days/wk) while using either an oral estradiol-progestin contraceptive (ORAL, n = 15), a contraceptive injection of depot medroxyprogesterone acetate (DEPO, n = 7), or no contraceptive (EU-OV, n = 14; control). Standardized physical fitness and exercise-heat tolerance tests (36.5°C, 37% relative humidity), administered before and after HAPT, demonstrated that the three subject groups successfully ( P < 0.05) acclimated to heat (i.e., rectal temperature, heart rate) and improved muscular endurance (i.e., sit-ups, push-ups, 4.6-km run time) and body composition characteristics. The stress of HAPT did not disrupt the menstrual cycle length/phase characteristics, ovulation, or plasma hormone concentrations of EU-OV. No between-group differences ( P > 0.05) existed for rectal and skin temperatures or metabolic, cardiorespiratory, muscular endurance, or body composition variables. A significant difference post-HAPT in the onset temperature of local sweating, ORAL (37.2 ± 0.4°C) vs. DEPO (37.7 ± 0.2°C), suggested that steroid hormones influenced this adaptation. In summary, virtually all adaptations of ORAL and DEPO were similar to EU-OV, suggesting that exogenous reproductive hormones neither enhanced nor impaired the ability of women to complete 7–8 wk of strenuous physical training and heat acclimation.

Effects of testosterone and estradiol on cutaneous vasodilation during local warming in older men

2007 ◽  
Vol 293 (5) ◽  
pp. E1426-E1429 ◽  
Author(s):  
Lynn A. Sokolnicki ◽  
Sundeep Khosla ◽  
Nisha Charkoudian
Keyword(s):  
Vascular System ◽  
Hormone Treatment ◽  
Older Men ◽  
Reproductive Hormones ◽  
Doppler Flowmetry ◽  
Healthy Men ◽  
Vasodilator Response ◽  
Before And After ◽  
Local Warming ◽  
The Impact

Microvascular vasodilation in humans can become impaired with age, leading to cardiovascular diseases ranging from mild to life-threatening. Reproductive hormones may confer some protection on the vascular system in women; however, it is unclear whether the same is true in men. Our goal was to evaluate the impact of four hormonal conditions (testosterone only, estradiol only, testosterone and estradiol, no testosterone and no estradiol) on microvascular vasodilator responsiveness in the skin of older men. We hypothesized that in older healthy men estradiol promotes cutaneous microvascular dilation during local warming of the skin and that testosterone inhibits this dilation. We measured skin blood flow using laser Doppler flowmetry during 35 min of cutaneous local warming to 42°C in 52 healthy men (average age 67 ± 1 yr). Subjects were randomized to one of the four hormonal conditions and were studied before and after hormone treatments. The endothelium-dependent vasodilator response to local warming was not different among groups either before or after hormone treatment. For example, with testosterone-only treatment this vasodilator response was 220 ± 13 AU, and with estrogen only the response averaged 246 ± 12 AU ( P > 0.05). We conclude that, within the doses employed in the present study, testosterone and estradiol did not consistently alter cutaneous vasodilator responsiveness in healthy older men.

SEMEN QUALITY AND REPRODUCTIVE HORMONES BEFORE AND AFTER ORCHIECTOMY IN MEN WITH TESTICULAR CANCER

1999 ◽  
pp. 822-826 ◽  
Author(s):  
PETER MEIDAHL PETERSEN ◽  
NIELS E. SKAKKEBAEK ◽  
MIKAEL RORTH ◽  
ALEKSANDER GIWERCMAN
Keyword(s):  
Testicular Cancer ◽  
Semen Quality ◽  
Reproductive Hormones ◽  
Before And After

SEMEN QUALITY AND REPRODUCTIVE HORMONES BEFORE AND AFTER ORCHIECTOMY IN MEN WITH TESTICULAR CANCER

1999 ◽  
Vol 161 (3) ◽  
pp. 822-826 ◽  
Author(s):  
PETER MEIDAHL PETERSEN ◽  
NIELS E. SKAKKEBAEK ◽  
MIKAEL RORTH ◽  
ALEKSANDER GIWERCMAN
Keyword(s):  
Testicular Cancer ◽  
Semen Quality ◽  
Reproductive Hormones ◽  
Before And After

scholarly journals The Effects of Short-Term Nutritional Stimulus Before and After the Luteolysis on Metabolic Status, Reproductive Hormones and Ovarian Activity in Goats

2009 ◽  
Vol 55 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Satoko HARUNA ◽  
Takenobu KUROIWA ◽  
Wengeng LU ◽  
Jahid ZABULI ◽  
Tomomi TANAKA ◽  
...  
Keyword(s):  
Reproductive Hormones ◽  
Metabolic Status ◽  
Ovarian Activity ◽  
Short Term ◽  
Before And After

scholarly journals Reproductive Hormonal Evaluation Of Female Mice After Treatment With Pentoxifylline

2009 ◽  
Vol 33 (2) ◽  
Author(s):  
Salema. L. Hassan
Keyword(s):  
Tap Water ◽  
Reproductive Organs ◽  
Reproductive Hormones ◽  
The Body ◽  
Control Group ◽  
Biochemical Tests ◽  
Body Weights ◽  
Before And After ◽  
Total Body ◽  
Hormonal Evaluation

The aim of this study was the assessment of pentoxifylline (PTX) effects on female reproductivehormones as well the body and reproductive organs. Sixty white mice with approximately same ages(eight) weeks and body weights were randomly divided into (six.) equal groups 10 mice for each group.Group 1: Received tap water along the period of experiment and considered as a control group. Animalsof group 2,3,4,5 and 6 were treated with 16 mg (PTX) / Kg B.W. daily for 2,4,6,8 and 10 weeksrespectively. Before and after treatment all animals were weighed, and blood samples were taken forfollicle stimulating hormone (FSH), lutenizing hormone (LH) and Estradiol (E2) hormones analysis.After post – Mortem examination reproductive organs were excised and weighed. The experimentrevealed that PTX administration caused increase in total body and reproductive organs weights.Concerning the biochemical tests results revealed elevation in concentration of FSH, LH and E2hormones especially significant (P<0.001) in treated groups of (8 and 10 wks duration). Compairedwith another animal groups conclusion. Administration of PTX in low dose for 10 weeks has asignificant effect on reproductive hormones. This will influence reproduction and litter size manifestedafter mating with untreated males.

Deformation Replication

1970 ◽  
Vol 28 ◽  
pp. 280-281
Author(s):  
J. Temple Black
Keyword(s):  
Cutting Speed ◽  
Machining Process ◽  
Depth Of Cut ◽  
Rake Face ◽  
Orthogonal Machining ◽  
Aluminum Chips ◽  
Before And After ◽  
Materials Used ◽  
Glass Knife ◽  
Very High

Tool materials used in ultramicrotomy are glass, developed by Latta and Hartmann (1) and diamond, introduced by Fernandez-Moran (2). While diamonds produce more good sections per knife edge than glass, they are expensive; require careful mounting and handling; and are time consuming to clean before and after usage, purchase from vendors (3-6 months waiting time), and regrind. Glass offers an easily accessible, inexpensive material ($0.04 per knife) with very high compressive strength (3) that can be employed in microtomy of metals (4) as well as biological materials. When the orthogonal machining process is being studied, glass offers additional advantages. Sections of metal or plastic can be dried down on the rake face, coated with Au-Pd, and examined directly in the SEM with no additional handling (5). Figure 1 shows aluminum chips microtomed with a 75° glass knife at a cutting speed of 1 mm/sec with a depth of cut of 1000 Å lying on the rake face of the knife.

Sign in / Sign up

Export Citation Format

Share Document