scholarly journals Management of Blood Supply and Blood Demand to Ensure International Health Security

2021 ◽  
Author(s):  
Amar Ibrahim Omer Yahia
Keyword(s):  
Blood Transfusion ◽  
Blood Supply ◽  
Negative Impact ◽  
International Health ◽  
Healthcare Services ◽  
Health Security ◽  
Proper Management ◽  
Health Authorities ◽  
Safe Blood ◽  
Blood Shortage

Maintaining international health security requires proactive and reactive activities and actions to minimise the negative impact of any health event that threatens public health. Blood transfusion services are a critical part of healthcare services, and blood and blood products can neither be synthesized nor stored for a long period. So, proper management of blood supply and blood demand is mandatory to preserve adequate safe blood. A failure to manage blood inventory and the resulting blood shortage are considered national and international health security threats because maintaining an adequate supply of safe blood is lifesaving for many patients. Blood shortages lead to the failure of blood transfusion services that ends with the collapse of the health system and health insecurity if health authorities do not take immediate corrective action. An imbalance between blood supply and blood demand is not only a threat to health security, but also poses some of the greatest threats to the national and international economy and security. The perception of health issues as an international health security threat is associated with benefits through attracting political and decision-makers’ attention and support. The global health policies and international health regulations concerning the management of blood supply and blood demand should be implemented and updated regularly. The information provided by this chapter addresses the management of blood supply and blood demand as an international health security issue and provides guidance in planning for proper management of blood inventory to avoid a sudden blood shortage and its catastrophic consequences.

scholarly journals Incidence and Determinants of Transfusion-Transmissible Infections in Voluntary Blood Donors in Malawi, 2005-2015

2019 ◽  
Author(s):  
Constance Wose Kinge ◽  
Juliana Kagura ◽  
Bridon M’baya ◽  
Stephen Njolomole ◽  
Charles Chasela
Keyword(s):  
High Risk ◽  
Blood Transfusion ◽  
Blood Supply ◽  
Blood Donors ◽  
Significant Risk ◽  
Secondary Data ◽  
Significant Risk Factor ◽  
Sub Saharan Africa ◽  
Sub Saharan ◽  
Safe Blood

Abstract Background Blood transfusion has been associated with a high risk of transfusion-transmissible infections (TTIs). These infections pose great threats to the availability and safety of blood supply for transfusion, particularly in sub-Saharan Africa (SSA) where the burden of disease is alarmingly high. We describe the incidence and determinants of TTIs to help target interventions for safety and increased access to safe blood. Methods This was secondary data analysis of a cohort of blood donors from the Malawi Blood Transfusion Service (MBTS) who donated blood from 2005–2015. Incidence was obtained by dividing the number of new cases by the total person-years at risk and survival probabilities computed by Kaplan-Meier estimates. Logistic regressions were used for risk factors. Results We analysed data from 47,075 registered blood donors of which the majority were male (84%) with a median age of 22 years (IQR=18–22). Of the registered donors, 3,439 (7.31%) were infected with at least one TTI (HIV, HCV or HBV). HBV was the most common TTI with 2.63% (n=1,238), followed by HIV with 1.74% (n=818) and HCV with 1.28% (n=602). Overall, TTI incidence was 43.4 per 10,000. Donors aged 20–24 (OR= 2.15, 95% CI= 1.35–3.40), and 30–34 (OR= 2.68, 95% CI= 1.67–4.32), males (OR= 1.65; 95% CI= 1.47–1.85), and married donors (OR= 1.93; 95% CI= 1.38–2.69) had significantly higher odds of TTI in the multivariate logistic model. Infection with syphilis was a common significant risk factor for incident HIV (OR= 2.62, 95% CI= 1.57–4.38), HCV (OR= 2.03, 95% CI= 1.04–3.98), and HBV (OR= 1.71, 95% CI= 1.01–2.89). Conclusion The overall incidence of TTIs in the Malawian donor population is comparatively low. The incidence of HIV, HCV and HBV is high in males, the unemployed, donors living in the Central Region, involved in high-risk sexual behaviour, and co-infected with syphilis. HBV is most common among supposedly healthy donors, followed by HIV and HCV. TTI therefore, remains a cause for concern toward availability and safe blood supply. Implementation of strict and proper donor selection criteria and continuous screening for TTI indicators can help maximise safe blood supply and transfusion.

scholarly journals Regulation of Blood and Blood products in India, USA and EU

2018 ◽  
Vol 6 (2) ◽  
pp. 72-84
Author(s):  
Swati Gupta ◽  
Harvinder Popli
Keyword(s):  
Blood Transfusion ◽  
Health Sector ◽  
Healthcare Services ◽  
Red Cross ◽  
Blood Products ◽  
The Past ◽  
Government Documents ◽  
Good Manufacturing Practices ◽  
Safe Blood ◽  
Developed Nations

Blood and blood products are precious commodity which gives life to another person. Though we have immense discoveries and invention in science and technology, yet we cannot make blood hence, human blood has no substitute. The availability of safe blood and blood products is essential for diverse modern healthcare services including some surgeries, treatments for cancer, chronic medical conditions, trauma care, organ transplantation, and childbirths that ultimately improve life for millions of patients who are need of transfusion annually. We do not have yet well-defined and stringent regulatory framework for blood products regulation. Frailty may arise from the inability of governments to enforce laws, regulations, and policies and personnel who may not aware or cannot follow quality assurance and/ or good manufacturing practices. While the health sector in developed nation has made outstanding accomplishments in the past few decades. The study sheds on the overview of blood transfusion system in India and other developed nations. There were a mix of methodologies, including literature review (government documents), interviews with key officials in Indian Red Cross Society and analysis of data was used. Results of analysis showed that there are several areas that need to be addressed as it potentially affect the timely availability of safe blood products, which calls for strengthening the planning and monitoring of blood transfusion services.

scholarly journals Prevalence of HIV in Blood Donors

1970 ◽  
Vol 6 (2) ◽  
pp. 93-97 ◽  
Author(s):  
B R Tiwari ◽  
S Karki ◽  
P. Ghimire ◽  
P. Yadav ◽  
M Rajkarnikar
Keyword(s):  
Blood Transfusion ◽  
Blood Supply ◽  
Blood Donors ◽  
Blood Donation ◽  
Cumulative Effect ◽  
Serum Samples ◽  
Total Blood ◽  
Hiv Seroprevalence ◽  
Blood Transfusion Service ◽  
Safe Blood

Background: Nepal is categorized as a country with ‘concentrated' epidemic of HIV Nepal Red Cross Society, Blood Transfusion Service has implemented considerable efforts to supply the safe blood and blood products according to the increasing demand. A trend analysis might prove valuable to understand the outcome and appropriately plan for further  improvements in providing safe blood supply. The study aimed to assess the trends of HIV seroprevalence over the six years in nationwide and in urbanized setting of Kathmandu Valley.Methods: This is a retrospective study conducted among Nepalese blood donors through the years 2001-2007. Serum samples were tested using third generation ELISA tests, strictly following the instructions of manufacturers. The donors' information was collected through the donor record register through the respective Blood Transfusion Services.Results: The overall seroprevalence of HIV among the total blood donors in nation wide and in Central Blood Transfusion Service (CBTS), Kathmandu through the six years of review (from 2001-2007) was 0.33% and 0.4% respectively. A significant decreasing trend in HIV seroprevalence was observed both in nationwide and in Central Blood Transfusion Service, Kathmandu (P< 0.001).Conclusion: The analysis of trends in HIV seroprevalence among blood donors through the year 2001- 2007 showed a significantly decreasing trend, probably due to the cumulative effect of increasing awareness of HIV and improved screening system for safe blood donation. However, an abrupt increase in demand of blood supply was associated with significant increase in seroprevalence in the year 2005/2006. Key words: Nepalese blood donors; Seroprevalence; Trends.doi: 10.3126/jnhrc.v6i2.2203Journal of  Nepal Health Research Council 2008 Oct;6(13): Page: 93-97 

scholarly journals Patient health engagement model: explaining citizens noncompliance and maladaptive behaviors

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
G Graffigna ◽  
S Barello ◽  
L Palamenghi ◽  
M Savarese ◽  
G Castellini
Keyword(s):  
Healthcare Services ◽  
Cross Sectional Study ◽  
Health Prevention ◽  
Prevention Measures ◽  
Cross Sectional ◽  
Health Authorities ◽  
Patient Health ◽  
Public Health Authorities ◽  
High Level ◽  
Restrictive Measures

Abstract Background At the end of February 2020 a new case was diagnosed with COVID-19 in north Italy, suddenly followed by new cases. Italian health authorities decided to enforce restrictive measures. Northern areas of Italy were identified as “red areas” to slow down the epidemic and its impact on the healthcare system. From this perspective, the COVID-19 epidemic in Italy constitutes a testing ground for the assessment of the ability of consumers to cope with this health risk. Methods A cross-sectional study on a representative sample of 1000 Italian citizens was conducted over the period 27 February- 5 March exploring the following hypotheses: 1) less engaged individuals are more concerned for the health emergency and feel more vulnerable; 2) less engaged have higher probability to develop negative attitudes and dysfunctional behaviors. Results only the 16% the interviewees presented a high level of engagement. Lower levels of engagement were measured in the southern parts of Italy (not yet touched by the epidemics at the time of data collection). People with lowers levels of engagement reported higher fears for the contagion and sense of vulnerability. Furthermore, they showed the lower levels of trust in the Public Health Authorities, in medical research and in vaccines. Finally, they appeared more dismissive in their preventive behaviors and more disorganized in the fruition of the healthcare services. Conclusions A psychological analysis of processes of attitudinal and role change in the direction of becoming more engaged in health prevention is worthy in order to forecast potential dysfunctional reactions to restrictive health prevention measures and to orient personalized education initiatives to consumers with different level of engagement. Key messages Profiling based on the levels of health engagement is important in order to plan more effective healthcare measures during epidemics. Targeted educational initiatives should take into account citizens' engagement profiles.

scholarly journals Posttraumatic Stress Disorder and Adjustment Disorder in Lithuanian Healthcare in 2018–2020: A Nation-Wide Cohort Study of the Effects of COVID-19 Pandemic

Healthcare ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1422
Author(s):  
Evaldas Kazlauskas ◽  
Odeta Gelezelyte ◽  
Auguste Nomeikaite ◽  
Paulina Zelviene
Keyword(s):  
Mental Health ◽  
Posttraumatic Stress Disorder ◽  
Mental Disorders ◽  
Posttraumatic Stress ◽  
Large Scale ◽  
Stress Disorder ◽  
Negative Impact ◽  
Adjustment Disorder ◽  
Healthcare Services ◽  
National Healthcare

Multiple empirical studies have revealed significant pandemic effects of COVID-19 on mental health in various populations. This study aimed to analyze the incidences of posttraumatic stress disorder (PTSD) and adjustment disorder (AjD) in national healthcare in 2018–2020 in one of the European countries—Lithuania—and estimate the effect of the COVID-19 pandemic on PTSD and AjD incidences in 2020. The national healthcare registry was used for estimations of diagnosis of PTSD, AjD, and major depressive disorder (MD). The study revealed that stress-related disorders PTSD and AjD are diagnosed rarely, resulting in a considerable gap between the expected prevalence and incidences of these diagnoses in healthcare in Lithuania. Moreover, a significant decline in mental disorders incidence in healthcare in 2020, in comparison to 2018 and 2019, was found, revealing that the COVID-19 pandemic had a negative impact on access to healthcare services and increased barriers for mental disorders treatment. The study indicates that major developments in building up knowledge about the effects of trauma and life stressors on mental health are needed in Lithuania and other countries to increase awareness about stress-related disorders and improve care for trauma survivors, in particular in the context of the pandemics or other large-scale disasters.

scholarly journals Persuasion Tactics in the Implementation of Large-Scale EHR Suites in Public Healthcare

2021 ◽  
Author(s):  
Gunnar Ellingsen ◽  
Bente Christensen ◽  
Morten Hertzum
Keyword(s):  
Large Scale ◽  
Healthcare Services ◽  
Governance Structure ◽  
Public Healthcare ◽  
Technical Literature ◽  
Health Authorities ◽  
To Come ◽  
Regional Health Authorities ◽  
Entrepreneurial Role ◽  
The U.S

Large-scale electronic health record (EHR) suites have the potential to cover a broad range of use needs across various healthcare domains. However, a challenge that must be solved is the distributed governance structure of public healthcare: Regional health authorities regulate hospitals, municipalities are responsible for first-line healthcare services, and general practitioners (GPs) have an independent entrepreneurial role. In such settings, EHR program owners cannot enforce municipalities and GPs to come on board. Thus, we examine what tactics owners of large-scale EHR suite programs apply to persuade municipalities to participate, how strongly these tactics are enforced, and the consequences. Empirically, we focus on the Health Platform program in Central Norway where the goal is to implement the U.S. Epic EHR suite in 2022. Theoretically, the paper is positioned in the socio-technical literature.

scholarly journals Haemovigilance: New approach for safe Blood transfusion

2019 ◽  
Vol 7 (4) ◽  
pp. 1-7
Author(s):  
Sravya Sree ◽  
Pasikhanti Shailaja
Keyword(s):  
Blood Transfusion ◽  
Adverse Reactions ◽  
Uttar Pradesh ◽  
Primary Objective ◽  
Family Welfare ◽  
Blood Collection ◽  
Blood Products ◽  
Preventive Actions ◽  
Potential Risks ◽  
Safe Blood

Haemovigilance is an urgent need of the country to identify and prevent occurrence or recurrence of transfusion related adverse reactions, thereby to increase the safety and quality of blood transfusion and blood products administration. Haemovigilance is an organised scheme of monitoring, identifying, reporting, investigating and analysing adverse events and reactions pertinent to transfusion and manufacturing blood products. Thus the information collected will facilitate corrective and preventive actions to minimise the potential risks associated with blood collection, processing and transfusion to patients. Indian Pharmacopoeia Commission has started a Haemovigilance Program of India (HvPI) in 2012 under its Pharmacovigilance Program of India (PvPI) in collaboration with National Institute of Biologicals (NIB), Noida, Uttar Pradesh, under Ministry of Health and Family welfare, Government of India with a primary objective to track adverse reactions/events and incidences associated with blood transfusion and blood product administration. The main objective of this article is to brief (s) about the system which monitors each and every step of transfusion reaction.

Communicable Diseases, Health Security, and Human Rights

2020 ◽  
pp. 221-242
Author(s):  
Sharifah Sekalala ◽  
John Harrington
Keyword(s):  
Human Rights ◽  
Disease Control ◽  
Communicable Disease ◽  
International Health ◽  
Early Response ◽  
Communicable Diseases ◽  
Essential Medicines ◽  
Health Security ◽  
Globalizing World ◽  
The Right

This chapter examines the influence of human rights in the quest to control communicable diseases. Communicable diseases are emerging and spreading faster than ever before, with devastating consequences for the most vulnerable in a rapidly globalizing world. Human rights have come to frame infectious disease control, beginning in the early response to AIDS and expanding from the stigmatization of marginalized populations to include the provision of essential medicines. Human rights claims have correspondingly expanded, arising out of norms of non-discrimination, consent, and privacy and now including the right to health. As individual rights compete with state authority, the World Health Organization’s (WHO’s) International Health Regulations (2005) aim to guide states in a rights-based response to communicable disease. However, as seen in recent Ebola outbreaks, human rights have lost priority to health security as the dominant frame for health policy, and this securitization of communicable disease control may undermine the gains of human rights, risking the future of global health.

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