scholarly journals Prevalence of HIV in Blood Donors

1970 ◽  
Vol 6 (2) ◽  
pp. 93-97 ◽  
Author(s):  
B R Tiwari ◽  
S Karki ◽  
P. Ghimire ◽  
P. Yadav ◽  
M Rajkarnikar
Keyword(s):  
Blood Transfusion ◽  
Blood Supply ◽  
Blood Donors ◽  
Blood Donation ◽  
Cumulative Effect ◽  
Serum Samples ◽  
Total Blood ◽  
Hiv Seroprevalence ◽  
Blood Transfusion Service ◽  
Safe Blood

Background: Nepal is categorized as a country with ‘concentrated' epidemic of HIV Nepal Red Cross Society, Blood Transfusion Service has implemented considerable efforts to supply the safe blood and blood products according to the increasing demand. A trend analysis might prove valuable to understand the outcome and appropriately plan for further  improvements in providing safe blood supply. The study aimed to assess the trends of HIV seroprevalence over the six years in nationwide and in urbanized setting of Kathmandu Valley.Methods: This is a retrospective study conducted among Nepalese blood donors through the years 2001-2007. Serum samples were tested using third generation ELISA tests, strictly following the instructions of manufacturers. The donors' information was collected through the donor record register through the respective Blood Transfusion Services.Results: The overall seroprevalence of HIV among the total blood donors in nation wide and in Central Blood Transfusion Service (CBTS), Kathmandu through the six years of review (from 2001-2007) was 0.33% and 0.4% respectively. A significant decreasing trend in HIV seroprevalence was observed both in nationwide and in Central Blood Transfusion Service, Kathmandu (P< 0.001).Conclusion: The analysis of trends in HIV seroprevalence among blood donors through the year 2001- 2007 showed a significantly decreasing trend, probably due to the cumulative effect of increasing awareness of HIV and improved screening system for safe blood donation. However, an abrupt increase in demand of blood supply was associated with significant increase in seroprevalence in the year 2005/2006. Key words: Nepalese blood donors; Seroprevalence; Trends.doi: 10.3126/jnhrc.v6i2.2203Journal of  Nepal Health Research Council 2008 Oct;6(13): Page: 93-97 

RETROSPECTIVE STUDY OF PREVALENCE OF HIV IN BLOOD DONORS AT A.D.GORWALA BLOOD BANK

2021 ◽  
pp. 42-43
Author(s):  
Neha Patel ◽  
Sanjay Chaudhari ◽  
Sonal Chitroda
Keyword(s):  
Retrospective Study ◽  
Blood Transfusion ◽  
Hiv Infection ◽  
Blood Donors ◽  
Blood Donation ◽  
Cumulative Effect ◽  
Blood Bank ◽  
Hiv Seroprevalence ◽  
Safe Blood ◽  
Anti Hiv

Background: India has the second highest HIV population in the world with about 2.5-3.0 million cases. Blood transfusion saves millions of lives worldwide each year but Blood transfusion is an important mode of transmission of infections to recipients and at the same time it is also associated with large number of complications including transfusion-transmissible infections (TTIs). Aims & objective: to study the prevalence of HIVin blood donors of A.D.Gorwala Blood bank From January 2005 To December 2010. Methods: A retrospective study was conducted among blood donors through the years 2005-2010. Sera from blood donors were tested for the detection of Anti HIV by using third generation ELISA tests, strictly following the instruction of manufacturers. The donor information was collected through the donor registers from A.D. Gorwala Blood Bank. Result: From the total of 28,371 screened blood samples collected, the prevalence of HIV in blood donors in the blood bank was 0.23% in the ve consecutive years but the trend of HIV infection has decreased from 2005(0.31%) to 2010 (0.04%). The age groups18-30 has the highest prevalence and the age group 51-60 was the lowest prevalence of HIV infection. The Prevalence of HIV among male (0.18%) was higher than in female donors (0.05%). The trend of HIVinfection was decreasing for both male and female blood donors. Conclusion: The analysis of HIV seroprevalence among blood donors through the year 2005- 2010 showed a signicantly decreasing trend, probably due to the cumulative effect of increasing awareness of HIVand improved screening system for safe blood donation.

scholarly journals Blood Transfusion Service and Hospital Blood Rotation: The Implications on Transfusion Safety in Nigeria

2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
High Rate ◽  
Blood Transfusion Service ◽  
First Time

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.

scholarly journals Incidence and Determinants of Transfusion-Transmissible Infections in Voluntary Blood Donors in Malawi, 2005-2015

2019 ◽  
Author(s):  
Constance Wose Kinge ◽  
Juliana Kagura ◽  
Bridon M’baya ◽  
Stephen Njolomole ◽  
Charles Chasela
Keyword(s):  
High Risk ◽  
Blood Transfusion ◽  
Blood Supply ◽  
Blood Donors ◽  
Significant Risk ◽  
Secondary Data ◽  
Significant Risk Factor ◽  
Sub Saharan Africa ◽  
Sub Saharan ◽  
Safe Blood

Abstract Background Blood transfusion has been associated with a high risk of transfusion-transmissible infections (TTIs). These infections pose great threats to the availability and safety of blood supply for transfusion, particularly in sub-Saharan Africa (SSA) where the burden of disease is alarmingly high. We describe the incidence and determinants of TTIs to help target interventions for safety and increased access to safe blood. Methods This was secondary data analysis of a cohort of blood donors from the Malawi Blood Transfusion Service (MBTS) who donated blood from 2005–2015. Incidence was obtained by dividing the number of new cases by the total person-years at risk and survival probabilities computed by Kaplan-Meier estimates. Logistic regressions were used for risk factors. Results We analysed data from 47,075 registered blood donors of which the majority were male (84%) with a median age of 22 years (IQR=18–22). Of the registered donors, 3,439 (7.31%) were infected with at least one TTI (HIV, HCV or HBV). HBV was the most common TTI with 2.63% (n=1,238), followed by HIV with 1.74% (n=818) and HCV with 1.28% (n=602). Overall, TTI incidence was 43.4 per 10,000. Donors aged 20–24 (OR= 2.15, 95% CI= 1.35–3.40), and 30–34 (OR= 2.68, 95% CI= 1.67–4.32), males (OR= 1.65; 95% CI= 1.47–1.85), and married donors (OR= 1.93; 95% CI= 1.38–2.69) had significantly higher odds of TTI in the multivariate logistic model. Infection with syphilis was a common significant risk factor for incident HIV (OR= 2.62, 95% CI= 1.57–4.38), HCV (OR= 2.03, 95% CI= 1.04–3.98), and HBV (OR= 1.71, 95% CI= 1.01–2.89). Conclusion The overall incidence of TTIs in the Malawian donor population is comparatively low. The incidence of HIV, HCV and HBV is high in males, the unemployed, donors living in the Central Region, involved in high-risk sexual behaviour, and co-infected with syphilis. HBV is most common among supposedly healthy donors, followed by HIV and HCV. TTI therefore, remains a cause for concern toward availability and safe blood supply. Implementation of strict and proper donor selection criteria and continuous screening for TTI indicators can help maximise safe blood supply and transfusion.

scholarly journals Blood Transfusion Service and Hospital Blood Rotation: The Implications on Transfusion Safety in Nigeria

2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
High Rate ◽  
Blood Transfusion Service ◽  
First Time

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.

scholarly journals Analysis of Blood Donor Deferral in a Tertiary Care Hospital

2020 ◽  
Vol 10 (2) ◽  
pp. 373-376
Author(s):  
Farida Parvin ◽  
Daanish Arefin Biswas ◽  
Bepasha Naznin ◽  
Tamanna Afroz ◽  
Mohammad Ali ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Medical Officer ◽  
Uncontrolled Hypertension ◽  
Care Hospital ◽  
Safe Blood ◽  
Donor Deferral

Introduction: Selection of proper donor according to stringent selection criteria is the prerequisite for safe blood transfusion practice. It is widely known that a large number of blood donors are deferred for different reasons. Objective: The aim of present study is to evaluate the incidence and different reasons of blood donor deferral in atertiary care hospital. Methodology: This retrospective cross-sectional study was carried out in Transfusion Medicine and Clinical Haematology Department of BIRDEM General Hospital, Dhaka, during the period from July 2016 to June 2017.The blood donor of either sex attending the mentioned department were selected purposively and categorized into four groups according to their age for this study. Donors were selected and deferred by medical officer according to national guideline. Deferred blood donors were recorded in register book and were analyzed retrospectively. Results: In current study, 1152 blood donor (8.8%) were deferred attending for allogeneic blood donation during the study period. Out of 13082 registered blood donor 11961were male (91.43%) and 1121 were female (8.57%) and deferral rate was 2.37 times more in female. Majority of the deferred donors (55.38%) were under the age of 40 where 26.82% were in between 40-49 years and 17.8% were in the range of 50 years and above. Age range of highest deferred donors (32.20%) was between 30-39 years. The number of temporary and permanent deferral were 836 (72.57 %) and 316 (27.43%) respectively. Anaemia (33.01%), underweight (21.53%) and hypotension (17.34%) were the most common reason of temporary deferral. Chronic uncontrolled hypertension (42.4%), donors with medication (16.77%) and asthma (15.18%) was the most common cause of permanent deferral. Conclusion: The deferral rate was low and most of the deferred donors were young adult. Temporary deferred donors were higher than permanent deferred donors. The most common reasons for temporary deferral were anemia, underweight and hypotension. Permanent deferral causes were chronic uncontrolled hypertension, donors on medication for various reason and asthma. Donors should be informed with a clear message on their deferral status. It is important to determine the rate and causes of donor deferral for the safety of blood transfusion and to guide the recruitment efforts for safe blood transfusion and to avoid the permanent loss of blood donors. Northern International Medical College Journal Vol.10 (2) Jan 2019: 373-376

Blood Transfusion Service and Hospital Blood Rotation: The Implications on Transfusion Safety in Nigeria

2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
High Rate ◽  
Blood Transfusion Service ◽  
First Time

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.

scholarly journals ANALYSIS OF PRE-DONATION DEFERRAL REASONS AMONGST BLOOD DONORS IN VADODARA, GUJARAT.

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Dr. Jhalak Patel ◽  
Dr. Milind Dighe ◽  
Dr. Farzana Kothari ◽  
Dr. Rahul Rajvanshi
Keyword(s):  
Blood Transfusion ◽  
Blood Donor ◽  
Health Care Policy ◽  
Blood Donors ◽  
Blood Donation ◽  
Blood Bank ◽  
Age Group ◽  
Donor Pool ◽  
Gender Based ◽  
Safe Blood

Background: Blood transfusion saves lives and improves health, but many patients requiring transfusion do not have timely access to safe blood. Providing safe and adequate blood should be an integral part of every country’s national health care policy and infrastructure. Aim: The main aim of the study was to analyze the reasons for pre-donation deferral amongst blood donors attending our blood bank and outdoor camp organized by our blood bank and to evaluate and categorize the reasons into temporary and permanent deferral. Materials and methods: It is a Record based Retrospective Study conducted in Department of Immunohematology and blood transfusion over a period of two years from July 2015 to July 2017. The reasons of deferral were analyzed after classification into following categories, namely, temporary- permanent deferral, in-house –camp blood donors, gender-based (male -female), and various age group categories. Results: A total of 30,022 prospective blood donors registered for blood donation out of which 2241 blood donors were deferred (7.46%) with low hemoglobin level, medication and hypertension as top three causes. The majority of deferral was seen in 18-25 years of age group which mainly comprises the youth population. The female donors were rejected eight times the male donors. Conclusion: The knowledge of the deferral incidences and their causes in a particular region helps in deciding the magnitude and the direction of the blood donor recruitment efforts. This knowl­edge also helps in calculating the eligible and the potential blood donor pool. Keywords: Blood Donors, Pre-Donation, Deferral, Temporary, Permanent.

A study of blood donor motivation in South Africa

2018 ◽  
pp. 158-163
Author(s):  
Richard M. Titmuss
Keyword(s):  
South Africa ◽  
Blood Transfusion ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Interview Data ◽  
Donor Motivation ◽  
Manual Worker ◽  
Blood Transfusion Service ◽  
Bantu Population

This chapter looks at a study of blood donor motivation in South Africa, which was commissioned by the Natal Blood Transfusion Service and carried out in Durban. Much of the fieldwork was done by six trained Bantu graduates which helps to explain the perceptive nature of some of the interview data elicited from poor and semi-literate Bantu workers. The study shows that the Bantu donor is statistically rare. They come mainly from institutional groups such as factories and schools and tend to be younger, better educated, and with higher incomes than the average Bantu adult in Durban. The concepts of blood held by the average manual worker Bantu closely link blood with health and are unfavourable to blood donation. Moreover, in the Bantu population at large there is widespread ignorance about, and fear of, blood donation. A marked characteristic of the Bantu blood donors is that they tend to give blood only once or twice.

scholarly journals Seroprevalence and trends of transfusion transmitted infections in blood donors of rural tertiary care hospital blood bank: a 3 year retrospective study in Chamba (HP)

2018 ◽  
Vol 5 (6) ◽  
pp. 2453
Author(s):  
Ishan Arora ◽  
Shairoly Singh ◽  
Shireen Singh
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Blood Bank ◽  
Care Hospital ◽  
Total Blood ◽  
Medical College ◽  
Disease Pattern ◽  
Donor Population

Background: Timely transfusion of blood saves millions of lives, but unsafe transfusion practices puts millions of people at risk of transfusion transmissible infections (TTIs). Blood transfusion carries the risk of transfusion-transmissible infections including human immunodeficiency virus (HIVI&II), hepatitis B virus (HBV), hepatitis C virus (HCV), malaria and syphilis. With every unit of blood there are 1% chances of transfusion associated diseases.Methods: This study was conducted over a period of 3 years (1stJanuary 2015-31st December 2017) at hospital blood bank of Pt. Jawaharlal Nehru Government Medical College, Chamba (H.P). The study was conducted on both voluntary and replacement blood donors who came to our blood bank and voluntary blood donation camps in and around Chamba. Statistical analysis used. Collected data was analyzed using appropriate statistical softwares such as EPI-INFO and MS-Excel.Results: In our study, we observed a total of 2616 donors over a period of 3 years. In the present study, 847 (32.37%) were voluntary donors and 1769 (67.62%) were replacement donors. Out of 2616 blood samples, 8 were HBsAg positive, 1 HCV positive.Conclusions: Our study shows that the number of blood donors is increasing every year. In our study, the seroprevalence of HBsAg was 0.3% and Hep C was 0.03% in total blood donors. The knowledge of current infectious disease pattern and trends in donor population can help in planning of future blood transfusion related health challenges. 

Seroprevalence of the hepatitis E virus antibodies among blood donors in the Qassim region, Saudi Arabia

2021 ◽  
Author(s):  
Bader Y Alhatlani ◽  
Waleed A Aljabr ◽  
Mohammed S Almarzouqi ◽  
Sami M Alhatlani ◽  
Rayan N Alzunaydi ◽  
...  
Keyword(s):  
Public Health ◽  
Saudi Arabia ◽  
Blood Transfusion ◽  
Hepatitis E Virus ◽  
Blood Donors ◽  
Indirect Elisa ◽  
Hepatitis E ◽  
Public Health Issue ◽  
Serum Samples ◽  
Major Public Health Issue

Aim: Hepatitis E virus (HEV) transmission through blood transfusion is a major public health issue worldwide. We aimed to determine the seroprevalence of HEV in blood donors in the Qassim region of Saudi Arabia. Materials & methods: Serum samples (n = 1078) were collected from volunteer blood donors and tested for the presence of anti-HEV IgG and IgM by indirect ELISA. Results: The seroprevalence of anti-HEV IgG among the blood donors was 5.7% overall. Anti-HEV IgG and IgM seropositivity were significantly higher in non-Saudi donors than in Saudi donors (22.1 vs 3 and 7.8 vs 0.2% for anti-HEV IgG and IgM, respectively). Conclusion: The seroprevalence of HEV among blood donors in the Qassim region was lower than previous estimates for other regions of the country and neighboring countries.

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