scholarly journals Post-extraction wound healing failure with long-term bone exposure related to sunitinib, a molecularly targeted drug

2014 ◽  
Vol 60 (8) ◽  
pp. 494-498
Author(s):  
Wataru KAKUGUCHI ◽  
Toyonori SUZUKI ◽  
Atsushi FUJITA ◽  
Kohei MATSUDA ◽  
Motoki YAHARA ◽  
...  
Keyword(s):  
Wound Healing ◽  
Targeted Drug ◽  
Molecularly Targeted Drug ◽  
Bone Exposure

Long-Term Cosmetic Benefit of Wound Healing by Betuline

2012 ◽  
Vol 29 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Hans-Robert Metelmann ◽  
Fred Podmelle ◽  
Peter D. Waite
Keyword(s):  
Wound Healing

scholarly journals A Case report-Ayurvedic Management of Dushta vrana

The Healer ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 123-125
Author(s):  
Pratigya Koju ◽  
Bijendra Shah ◽  
Shiva Mangal Prasad ◽  
Raj Kishor Shah
Keyword(s):  
Wound Healing ◽  
Malignant Disease ◽  
Signs And Symptoms ◽  
Lower Limbs ◽  
Local Factors ◽  
Healing Wound ◽  
Per Oral ◽  
Tissue Tension

            The break/loss/rupture of contuinity of body tissue or part of body is called Vrana(Wound). Normally wounds are healed by itself if kept clean.Contamination of bacteria, insufficient blood supply, tissue tension and radiation are the local factors for delay in wound healing. Whereas general factors include malnutrition, malignant disease,diabetes and long term consumption of steroids and cytotoxic drugs.[i]Acharya Shushruta mentioned 60 upakrama for management of Vrana. Acharya charaka classified vrana into 20 types among them dustha vrana is one of them.[ii]In the case 35 yr female presented at opd with complain of non healing wound since 6 months at bilateral lower limbs with signs and symptoms of slough,pus discharge and pain.Ayurvedic management was done for 30 days which cured all the sign and symptoms. Ayurvedic management includes prakshalana by panchavalkal kwath, nimba taila for local application and arogyabardini vati,mahamanjistha kwath and kaishor guggulu per oral. Conclusion: Dustha vrana can be treated by ayurvedic management like panchavalkal kwatha, nimba taila,Arogyavardini vati kaishor guggulu, mahamanjistha kwath.   [i] RAINS A.J.HARDING,  RITCHIE H DAVID in Bailey and Loves Short Practice of Surgery 19th Edition Chapter 1  pg 3 [ii] Acharya Bidhyadhar Shukla,Prof.Rabidutta Tripathi in Charak Samhita Uttarardha Reprinted 2010 chapter 25 pg606

scholarly journals PROSES PENYEMBUHAN LUKA ULKUS DIABETIKUM DENGAN METODE MODERN DRESSING DIKLINIK MAITIS EFRANS WOUND CARE

2018 ◽  
Vol 10 (2) ◽  
pp. 146-151
Author(s):  
Nadya Putri Nabila
Keyword(s):  
Diabetes Mellitus ◽  
Wound Healing ◽  
Wound Care ◽  
Healing Process ◽  
Case Study Research ◽  
World Population ◽  
Care Clinic ◽  
Diabetic Ulcer ◽  
Patients With Diabetes

Diabetes mellitus (DM) is one of the most common chronic diseases experienced by the world population and ranks fourth cause of death in developing countries. Long-term complications of diabetes mellitus one of them is diabetic ulcer (15%) and is the most cause (85%) of amputation in patients with diabetes mellitus. Currently, more than 5,000 modern types of dressings are reported to be available to treat wounds, especially diabetic ulcers. To know the process of wound healing diabetic ulcer was done with the design of case study research with a sample of 2 people and this study was conducted for 4 weeks. The study was conducted at the Maitis Efrans Wound Care clinic in Bengkulu City. The result was obtained that the assessment of diabetic ulcer wounds before modern wound care on the respondents was a total score of 54 and the respondents two total score of 50 were stated wound regeneration. The healing process of the responder's second ulcers progressed, the total score of one respondent was 30 and the respondent two was 28. Respondents. Progress on the two respondents stated better influenced by wound healing factor that is, age factor.

scholarly journals Short- and Long-Term Effects of IL-1 and TNF Antagonists on Periodontal Wound Healing

2004 ◽  
Vol 173 (5) ◽  
pp. 3514-3523 ◽  
Author(s):  
Xuemei Zhang ◽  
Malika Kohli ◽  
Qingde Zhou ◽  
Dana T. Graves ◽  
Salomon Amar
Keyword(s):  
Wound Healing ◽  
Long Term Effects ◽  
Tnf Antagonists ◽  
Short And Long Term ◽  
Periodontal Wound Healing

Nutrition

2019 ◽  
pp. 188-196
Author(s):  
George W. Williams
Keyword(s):  
Infectious Disease ◽  
Wound Healing ◽  
Critical Care ◽  
Nutritional Status ◽  
Respiratory Function ◽  
Surgical Patients ◽  
Nutritional Management ◽  
Equal Degree ◽  
Perioperative Nutrition

Nutrition is the second of two principal concepts (the first being infectious disease) in critical care not heavily emphasized in core anesthesiology training for reasons that are obvious. Optimal nutritional management is imperative to achieve positive outcomes in surgical patients. Wound healing, mobilization, and respiratory function are all particularly affected by nutritional status, and the optimal application assessment of nutrition directly affects surgical patients in the long term. Clinically, many physicians may take nutrition for granted and potentially conclude that it is not acutely important. Following consuming this content, the reader will be better equipped to educate their colleagues on the optimal assessment and application of perioperative nutrition. This chapter provides clinically useful and examination-oriented substrate to an equal degree, while being optimally digestible by the reader (no pun intended).

scholarly journals Effect of small molecular weight soybean protein-derived peptide supplementation on attenuating burn injury-induced inflammation and accelerating wound healing in a rat model

RSC Advances ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 1247-1259 ◽  
Author(s):  
Fen Zhao ◽  
Wei Liu ◽  
Yonghui Yu ◽  
Xinqi Liu ◽  
Huinan Yin ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Wound Healing ◽  
Rat Model ◽  
Burn Injury ◽  
Soybean Protein ◽  
Burn Injuries ◽  
Small Molecular Weight

The populations most afflicted by burn injuries have limited abilities to support the significant specialized requirements and costs for acute and long-term burn injury care.

Investigation of Wound Healing after Paranasal Sinus Surgery with Time Lapse Video—A Pilot Study

1996 ◽  
Vol 10 (4) ◽  
pp. 235-238 ◽  
Author(s):  
Rainer Weber ◽  
Rainer Keerl ◽  
Andreas Huppmann ◽  
Bernhard Schick ◽  
Wolfgang Draf
Keyword(s):  
Wound Healing ◽  
Paranasal Sinus ◽  
Time Lapse ◽  
Sinus Surgery ◽  
Computer Assisted ◽  
Surgical Trauma ◽  
Topical Steroids ◽  
Whole Process ◽  
Paranasal Sinus Surgery

We describe a new method of documentation of the dynamics of the nature of wound healing after endonasal paranasal sinus surgery. This was not possible until now and is achieved by the computer-assisted interpolation known as morphing. We evaluated six patients with chronic polypoid sinusitis of similar extent who underwent 12 complete endonasal micro-endoscopic pansinus operations. It is difficult to describe the overlapping and meshing phases sufficiently in words. They are much more easily understood by looking at the whole process in its natural dynamic on a video screen. Wound healing after complete endonasal pansinus operation lasts over 6 months. Scar remodelling has not yet finished at this time. The following measures are recommended for decreasing postoperative granulations, edema, and swelling: minimizing the surgical trauma, long-term packing with an occlusive, nonadherent material (rubber finger packing), and topical steroids (Budesonide).

Serum iron levels as new predictive factor in FOLFOX/FOLFIRI with or without molecularly targeted drug therapy.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e14004-e14004
Author(s):  
Takumi Ochiai ◽  
Kazuhiko Nishimura ◽  
Tomoo Watanabe ◽  
Masayuki Kitajima ◽  
Akinori Nakatani ◽  
...  
Keyword(s):  
Drug Therapy ◽  
Predictive Factor ◽  
Serum Iron ◽  
Rank Test ◽  
Targeted Drugs ◽  
Number Of Patients ◽  
Rate Of Increase ◽  
Increase Rate ◽  
Targeted Drug ◽  
Molecularly Targeted Drug

e14004 Background: An increase in serum iron levels after administration of various anticancer drugs was reported (Follezou et al, NEOPLASMA 1985). We have also reported an increase in serum iron levels during FOLFOX and FOLFIRI therapies (ASCO 2009: #e15110) and a correlation between prognosis and transition of serum iron levels in advanced colorectal cancer (CRC) patients (ASCO 2011: #e14141). The aim of this cohort study was to evaluate the correlation between prognosis and serum iron levels in advanced CRC patients treated with FOLFOX/FOLFIRI ± molecularly targeted drugs. Methods: Serum iron levels were measured before and at 48 hr after treatment (FOLFOX/FOLFIRI ± molecularly targeted drugs) in 69 advanced CRC patients, all of whom died between December 2005 and December 2011. No patients were treated with radiotherapy. Taking the median rate of increase in serum iron levels as the cut-off value in each therapy, the patients were categorized into cohort I (increase rate over cut-off value in at least one therapy) and cohort II (increase rate under the cut-off value in all therapies). Prognosis was evaluated between the two cohorts using the Kaplan-Meier method and the log rank test. Results: No significant bias in patient characteristics was observed between the two cohorts. Serum iron levels transiently increased after treatment (p<0.001), then returning to baseline within 2 weeks. Median survival time (MST) in cohort I (n: 41) and cohort II (n: 28) was 430 and 377 days, respectively. The MST was significantly better in cohort I (p=0.0496). No significant differences were observed in the frequency of chemotherapies or number of patients treated with molecularly targeted drugs between the two cohorts. Conclusions: Cohort I showed a statistically significant better prognosis. The results suggest that serum iron levels could be used as a new predictive factor in FOLFOX/FOLFIRI ± molecularly targeted drug therapy. In Cohort II patients, molecularly targeted drugs should be used positively for further improvement in prognosis.

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