scholarly journals Evaluation of Memory Complaints in People Living with HIV in Iran

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Malihe Sheibani ◽  
Nurallah Mohammadi ◽  
Hassan Joulaei ◽  
Zohre Foroozanfar

Background: Several studies have reported that many people living with HIV (PLHIV) complain of memory impairments. Objectives: This study aimed to investigate these complaints both subjectively and objectively. Patients and Methods: For this purpose, 50 PLHIV and 50 of their companions as the control group were selected by the convenience sampling method in Shiraz, Iran, and completed Ray's auditory-verbal learning test and the Patient’s Assessment of Own Functioning Inventory (PAOFI). Data were analyzed using a t-test in SPSS. Results: Our findings showed a significant difference between PLHIV and the control group in terms of subjective memory complaints and objective memory functions. Conclusions: The overall result of the study showed that PLHIV reported more subjective memory complaints and poorer objective memory functions than the control group, regardless of the stage of the disease.

2021 ◽  
Vol 18 ◽  
Author(s):  
Merav Papirovitz ◽  
Ariela Gigi

Background: Subjective memory complaints are a key component in mild cognitive impairment (MCI) diagnosis. However, studies that examined memory awareness among MCI participants have published contradictory results. One possible explanation for the inconsistent findings could be the disregard from the multidimensional structure of subjective memory. Objectives: The present study is directed at assessing subjective memory among healthy and MCI participants, referring to three main types of memory: episodic, semantic, and working memory. Method: Participants were 123 adults (aged 50-90). They were divided into two groups, the MCI group, and the control group, according to their objective cognitive performance in RAVL or Mo- CA tests. All participants filled a subjective memory questionnaire, assessing their awareness of episodic, semantic, and working memory. Results: MCI participants estimated their semantic memory as significantly lower in comparison to the estimation of the healthy controls. By contrast, MCI participants showed an overestimation of their episodic memory capabilities compared to the control group. No significant difference was found between groups (MCI and healthy controls) in evaluating their working memory. In addi- tion, for both groups, Pearson’s correlation revealed a significant negative correlation between age and semantic memory evaluation. Such correlation was not found for subjective episodic memory. Discussion: Findings suggest that while people with MCI exhibit poor awareness of their episodic and working memory capabilities, their awareness of their decrease in semantic memory is appar- ently intact. Therefore, it is suggested that when using the self-report criterion for MCI diagnosis, clinicians should consider the patient’s’ semantic memory complaints.


2013 ◽  
Vol 26 (3) ◽  
pp. 463-473 ◽  
Author(s):  
J. Lehrner ◽  
D. Moser ◽  
S. Klug ◽  
A. Gleiß ◽  
E. Auff ◽  
...  

ABSTRACTBackground:The goals of this study were to establish prevalence of subjective memory complaints (SMC) and depressive symptoms (DS) and their relation to cognitive functioning and cognitive status in an outpatient memory clinic cohort.Methods:Two hundred forty-eight cognitively healthy controls and 581 consecutive patients with cognitive complaints who fulfilled the inclusion criteria were included in the study.Results:A statistically significant difference (p < 0.001) between control group and patient group regarding mean SMC was detected. 7.7% of controls reported a considerable degree of SMC, whereas 35.8% of patients reported considerable SMC. Additionally, a statistically significant difference (p < 0.001) between controls and patient group regarding Beck depression score was detected. 16.6% of controls showed a clinical relevant degree of DS, whereas 48.5% of patients showed DS. An analysis of variance revealed a statistically significant difference across all four groups (control group, SCI group, naMCI group, aMCI group) (p < 0.001). Whereas 8% of controls reported a considerable degree of SMC, 34% of the SCI group, 31% of the naMCI group, and 54% of the aMCI group reported considerable SMC. A two-factor analysis of variance with the factors cognitive status (controls, SCI group, naMCI group, aMCI group) and depressive status (depressed vs. not depressed) and SMC as dependent variable revealed that both factors were significant (p < 0.001), whereas the interaction was not (p = 0.820).Conclusions:A large proportion of patients seeking help in a memory outpatient clinic report considerable SMC, with an increasing degree from cognitively healthy elderly to aMCI. Depressive status increases SMC consistently across groups with different cognitive status.


2020 ◽  
pp. 1-12
Author(s):  
Sarah M. Goldberg ◽  
Oscar L. Lopez ◽  
Ann D. Cohen ◽  
William E. Klunk ◽  
Howard A. Aizenstein ◽  
...  

ABSTRACT Objectives: This study investigated subjective memory complaints in older adults and the roles of setting, response bias, and personality. Design: Cognitively normal older adults from two settings completed questionnaires measuring memory complaints, response bias, and personality. Settings: (A) Neuroimaging study with community-based recruitment and (B) academic memory clinic. Participants: Cognitively normal older adults who (A) volunteer for research (N = 92) or (B) self-referred to a memory clinic (N = 20). Measurements: Neuropsychological evaluation and adjudication of normal cognitive status were done by the neuroimaging study or memory clinic. This study administered self-reports of subjective memory complaints, response bias, five-factor personality, and depressive symptoms. Primary group differences were examined with secondary sensitivity analyses to control for sex, age, and education differences. Results: There was no significant difference in over-reporting response bias between study settings. Under-reporting response bias was higher in volunteers. Cognitive complaints were associated with response bias for two cognitive complaint measures. Neuroticism was positively associated with over-reporting in evaluation-seekers and negatively associated with under-reporting in volunteers. The relationship was reversed for Extraversion. Under-reporting bias was positively correlated with Agreeableness and Conscientiousness in volunteers. Conclusion: Evaluation-seekers do not show bias toward over-reporting symptoms compared to volunteers. Under-reporting response bias may be important to consider when screening for memory impairment in non-help-seeking settings. The Memory Functioning Questionnaire was less sensitive to reporting biases. Over-reporting may be a facet of higher Neuroticism. Findings help elucidate psychological influences on self-perceived cognitive decline and help seeking in aging and may inform different strategies for assessment by setting.


2008 ◽  
Vol 2 (1) ◽  
pp. 42-45 ◽  
Author(s):  
Paulo Caramelli ◽  
Rogério Gomes Beato

Abstract Memory loss is a major complaint among the elderly population. However, the clinical significance of this symptom is variable and also controversial in the scientific literature. Objective: To compare the cognitive performance of two groups of healthy elderly, one group with and the other without, subjective memory complaints (SMC). Methods: Sixty cognitively intact elderly individuals (39 females and 21 males), aged 69.9±6.3 years and with educational level of 8.5±5.5 years, were included in the study. Participants were submitted to the Mini-Mental State Examination and to the Cornell depression scale in order to rule out global cognitive impairment and depression, respectively. Moreover, they answered the MAC-Q, a questionnaire devised to evaluate subjective impression of memory function. Subsequently, they were submitted to the digit span forward and backward, the Brief Cognitive Screening Battery, and to the Frontal Assessment Battery. Results: Twenty-seven individuals had MAC-Q scores <25 and thus were classified as not having SMC, while 33 had MAC-Q scores ³25 and were considered to have SMC. No differences for age, gender, education and MMSE scores were found between the two groups. The comparison between the performance of the groups of complainers and non-complainers on the different cognitive tests yielded no significant difference, although there was a trend toward non-complainers performing better on incidental memory. Conclusions: The presence of SMC was not associated to objective memory impairment or to other cognitive deficits in this group of elderly individuals.


2010 ◽  
Vol 4 (1) ◽  
pp. 54-57 ◽  
Author(s):  
Ana Cristina Procópio de Oliveira Aguiar ◽  
Miriam Ikeda Ribeiro ◽  
Alessandro Ferrari Jacinto

Abstract Prevalence of subjective memory complaints (SMC) in elderly community dwellers (ECD) ranges from 25 to 50%. Some controversy exists over the association between SMC and cognitive status. Objective: We investigated whether a correlation in cognitive performance existed between two different groups according to SMC. Methods: The Mini Mental State Examination (MMSE) and Dementia Rating Scale-Mattis (DRS-Mattis) were applied to two groups: ECD (n=14) with SMC and residents (n=14) of a long-term care facility (LTCF) without SMC. Results: The median age in the ECD group was 81.0 years, and in the LTCF group was 75.0 years. There was a statistically significant difference (p=0.048) between these groups regarding age. Concerning schooling (1-8 or ³9 years), there was no statistically significant difference between the groups (p=0.638). No statistically significant difference between the two groups was found for scores on the cognitive tests. Conclusion: SMC might be related to extrinsic factors other than insipient cognitive decline.


Jurnal NERS ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. 183
Author(s):  
Untung Sujianto

Introduction: HIV patients often experience psychological and physical disorders which greatly affect the adherence of people living with HIV/AIDS (PLWHA). This study aimed to assess the effects of aerobic exercise on the levels of depression and CD4 cell count of HIV patients.Methods: This study used a pre-post quasi-experimental design with a control group. The sampling technique was consecutive sampling, with a total sample of 52 HIV respondents. Depression level was measured using the Beck Depression Inventory (BDI), while CD4 count was measured using the Pyma analyser. The aerobic exercise intervention was given three times a week with a duration of 20-30 minutes each for four weeks. The collected data were analysed using a paired sample t-test and an independent sample t-test.Results: The results showed a significant difference in the mean value of depression before and after the intervention of aerobic exercise (M =25.15 and M=22.46, respectively) with p = 0.001. Similarly, there was a significant difference in the mean of CD4 counts between the control group (M=303.38) and the intervention group (M=305.38) after the intervention with p = 0.031.Conclusion: Aerobic exercise is effective in reducing depression levels and increasing CD4 counts in HIV patients. Immune system cells circulate more rapidly and there is a boost in the production of macrophages, cells that can attack bacteria.


2019 ◽  
Vol 34 (6) ◽  
pp. 911-911
Author(s):  
H VanLandingham ◽  
L Alasantro ◽  
G Wagner ◽  
J Rosen

Abstract Objective A weak relationship exists between subjective memory complaints and performance on objective measures of learning and memory. A memory catastrophizing scale may explain this relationship. Our objective is to preliminarily explore a scale which assesses catastrophizing. Method The sample consisted of 46 patients (21 normal profiles, 25 mild cognitive impairment; mean age 56.1 ± 15.4) in a community-based neurology clinic. Each patient completed a clinical interview and comprehensive neuropsychological battery. The California Verbal Learning Test II (CVLT-II) was used to assess memory; the Beck Depression Inventory and Beck Anxiety Inventory were used to assess depressive and anxiety symptoms; a novel Memory Catastrophizing Scale (MCS) was used to assess subjective memory. Results A reliability analysis revealed internal consistency throughout the MCS (Cronbach’s alpha = .958). A bivariate correlation revealed that memory catastrophizing was significantly positively correlated with depressive (r = 0.623, p < 0.01) and anxiety (r = 0.433, p < 0.01) symptomology. Bivariate correlations demonstrated significant positive correlations between subjective memory complaints and memory (CVLT-II SDFR r = 0.502, p < .05; SDCR r = 0.434, p = 0.05; LDCR r = 0.512, p < .05) only among NP patients. The mean MCS score was 26 (±17), with a median of 17, a skewness of 0.40 and kurtosis of -0.77. Conclusion Our results support past research suggesting that there is a weak relationship between subjective and objective memory performances. Catastrophizing as a concept may explain the relationship between mood and performance on testing, especially amongst individuals without a known neurological pathology seeking treatment at a community-based neurological clinic.


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