scholarly journals Evaluation of Cardiac Troponin Level Following Generalized Tonic-Clonic Seizure in Children; Cross-Sectional Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Yazdan Ghandi ◽  
Fakhreddin Sharitmadari ◽  
Danial Habibi ◽  
Saeid Sadrnia
Keyword(s):  
Cardiac Troponin ◽  
Troponin I ◽  
Cardiac Injury ◽  
Cross Sectional Study ◽  
Clonic Seizure ◽  
Cardiac Monitoring ◽  
Cardiac Damage ◽  
Cross Sectional ◽  
History Of ◽  
The Mean

Objectives: Cardiac troponin I (CTnI) is recognized as a proper marker for early detection of cardiac damage. Generalized tonic-clonic (GTC) seizures may lead to cardiac ischemia or myocardial injury associated with elevated CTnI. The present study aimed at evaluating the level of CTnI in children with status GTC seizures. Methods: 50 patients with GTC seizures and a normal cardiac function referred to Amirkabir Hospital, Arak, Iran were evaluated. The medical history of all patients was taken, and clinical examinations were performed. For all patients were performed Serum CTnI measurements, electroencephalography (EEG), electrocardiography (ECG), and echocardiography. Results: The patients’ mean age was 7.80 ± 4.01 years and 26 (52%) children were female (female: male ratio, 1.08). the mean duration of seizure was 31.54 ± 1.56 minutes. Abnormal EEG patterns were documented in 83 (86%) patients, while abnormal CT scan was not found in any of the patients. The mean level of CTnI was at the high end of the range in patients (57.02 ± 10.80 ng/mL). There was a positive correlation between serum CTnI and age (P = 0.001, R = 0.492). Also, the serum level of CTnI was significantly correlated with the onset of GTC seizure (R = 0.004, P = 0.001). Conclusion: The serum CTnI level exceeded the normal level in children with seizures. Therefore, cardiac monitoring of patients with status GTC seizures may be helpful in the ictal and postictal phases for evaluating cardiac injury, especially in children with risk factors for coronary diseases, such as Kawasaki disease, cardiomyopathy, or coronary anomalies.

scholarly journals Analysis of Cardiac Injury Biomarkers in COVID-19 Patients

2020 ◽  
Vol 15 (4) ◽  
Author(s):  
Salma Abdeladim ◽  
Sara Oualim ◽  
Amal Elouarradi ◽  
Ilham Bensahi ◽  
Rita Aniq Filali ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Troponin I ◽  
Cardiac Injury ◽  
Clinical Syndrome ◽  
Cardiac Troponin I ◽  
The Novel ◽  
Cardiac Damage ◽  
The Mean ◽  
Underlying Mechanisms ◽  
Novel Coronavirus

Background: Infection with the novel coronavirus, named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), producing a clinical syndrome known as COVID-19, is a budding infectious disease that first manifested in December 2019 in China and subsequently spread worldwide. Objectives: We performed an analysis of cardiac injury markers to determine their usefulness as predictors of severity and mortality Methods: In a retrospective study, we enrolled 73 patients with confirmed diagnoses of COVID-19, from March 21, 2020, to April 24, 2020. Serial tests of cardiac injury markers, including cardiac troponin I (cTnI), N‐terminal pro‐brain natriuretic peptide (NT‐proBNP), and Lactate dehydrogenase (LDH), were considered for the analysis of potential cardiac damage. Results: Among 149 patients with confirmed COVID-19, data from 73 patients were studied. Of them, 58 (79.46%) patients were discharged, and 15 (20.54 %) patients died. The mean age was 58.50 (14.66) years. Patients were classified into mild (39 cases), severe (17 cases), and critical (17 cases) groups. The peak cardiac troponin I level (0.11 ng/mL [IQR: 0.33–0.20]), peak NT-pro BNP level (5840.35 pg/mL [IQR: 1609.39 – 10071.32]), and peak LDH level (578.65 UI/l[IQR: 313.40 – 843.90]) were significantly higher in the critical group, and the three cardiac injury parameters were significantly higher in the death group, suggesting that they are significantly associated with a higher risk of in-hospital mortality. Conclusions: The understanding of cardiovascular system injury caused by SARS-CoV-2 and its underlying mechanisms is of great importance for the early clinical management of these patients and mortality reduction.

scholarly journals TO STUDY THE ONSET AND PROGRESSION OF AIRWAY ABNORMALITY IN TERMS OF ALTERATION IN PFT IN ASYMPTOMATIC SMOKERS.

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Significant Difference ◽  
History Of ◽  
Young Smokers ◽  
The Mean ◽  
Group Ii

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers

scholarly journals Determinants of anemia among pregnant women: A hospital based cross sectional study

2019 ◽  
Vol 8 (9) ◽  
pp. 3609
Author(s):  
P. Kalpana ◽  
A. Kavitha
Keyword(s):  
Pregnant Women ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Hemoglobin Level ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lower Segment Cesarean Section ◽  
Menstrual History ◽  
History Of ◽  
The Mean

Background: The objective was to study the determinants of anemia among pregnant women. There is a negative effect on the health of the mother and as well as that of the child due to anemia in women with pregnancy. Death rate is more in women who are pregnant and having anemia. The objective of this study was to study the determinants of anemia among pregnant women.Methods: A hospital based cross sectional study was carried out among 40 pregnant women over a period of six months. Demographic data like age, residence, occupation etc was recorded. Obstetric data like gravida, parity, previous LSCS was also recorded. The data was presented as means and student’s t test was applied.Results: The mean age was 23.43±3.4 years. Majority were young between the ages of 19-22 years. Majority belonged to urban residents i.e. 57.5%. 20% of the subjects were found to be illiterate. Majority of the mothers were housewives i.e. 82.5%. Majority were multi-gravida i.e. 60%. Majority had no history of abortions in the past i.e. 75%. Out of total 19 repeat pregnancies, majority i.e. 84.2% had lower segment cesarean section. Majority reported that they had normal menstrual history. The mean hemoglobin level was found out to be 7.94 gm/dl. It was found that the mean hemoglobin level did not differ significantly across age, residence, education, occupation, gravidity, history of abortions, type of delivery but differed significantly by abnormal menstrual cycle.Conclusions: Mean hemoglobin level was more in women with normal menstrual history compared to those women with abnormal menstrual history and this difference was found out to be statistically significant. Hence abnormal menses should be promptly treated, hemoglobin assessed.

scholarly journals Factors influencing Fear of Falling in Community-Dwelling Older Adults in Singapore: A Cross-Sectional Study

2021 ◽  
Author(s):  
Jacqueline Giovanna De Roza ◽  
David Wei Liang Ng ◽  
Blessy Koottappal Mathew ◽  
Teena Jose ◽  
Ling Jia Goh ◽  
...  
Keyword(s):  
Older Adults ◽  
Fear Of Falling ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Clinical Factors ◽  
Cross Sectional ◽  
Frail Older Adults ◽  
History Of ◽  
The Mean ◽  
Community Dwelling Older Adults

Abstract BackgroundFalls in older adults is a common problem worldwide. Fear of falling (FoF) is a consequence of falls which has far-reaching implications including activity restriction, functional decline and reduced quality of life. This study aimed to determine the factors associated with FoF in a segment of Singapore’s community-dwelling older adults. MethodsThis descriptive cross-sectional study recruited a convenience sample of adults aged 65 and above from 4 primary care clinics from September 2020 to March 2021. Data were collected on demographic factors and clinical factors including history of falls and frailty as determined by the Clinical Frailty Scale (CFS). FoF was measured using the Short Falls Efficacy Scale–International (Short FES-I), cut-off score of 14 and above indicated high FoF. Logistic regression was used to determine predictors of high FoF.ResultsOut of 360 older adults, 78.1% were Chinese and 59.7% females. The mean age was 78.3 years and 76 (21.1%) had a history of falls in the past six months. Almost half (43.1%) were mildly to moderately frail and most (80.6%) had three or more chronic conditions. The mean FoF score was 15.5 (SD 5.97) and 60.8% reported high FoF. Logistic regression found that Malay ethnicity (OR = 5.81, 95% CI 1.77 – 19.13), use of walking aids (OR = 3.67, 95% CI = 1.54 – 8.77) and increasing frailty were significant predictors for high FoF. The odds of high FoF were significantly higher in pre frail older adults (OR = 6.87, 95% CI = 2.66 – 17.37), mildly frail older adults (OR =18.58, 95% CI = 4.88 – 70.34) and moderately frail older adults (OR = 144.78, 95% CI = 13.86 – 1512.60).ConclusionsFoF is a prevalent and compelling issue in community-dwelling older adults, particularly those with frailty. The demographic and clinical factors identified in this study will be helpful to develop targeted and tailored interventions for FoF.

scholarly journals Cardiovascular Diseases’ Awareness Among Women in Northern Jordan

2019 ◽  
Vol 11 (3) ◽  
pp. 102
Author(s):  
Abdulhakeem M Okour ◽  
Rami A Saadeh ◽  
Neda Redwan ◽  
Muhammad Faizal Bin A. Ghani
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Cross Sectional Study ◽  
Demographic Information ◽  
Cross Sectional ◽  
Related Risk ◽  
History Of ◽  
Treatment Plans ◽  
The Mean ◽  
Health Objectives

BACKGROUND: Women’s awareness of chronic diseases, including cardiovascular diseases, is the cornerstone in promoting women’s health. Objectives: To examine the relationship of awareness levels about cardiovascular diseases and their related risk factors with demographic information of Jordanian women. METHODS: A cross-sectional study of 18 years and older women. Scores of awareness were computed for each individual and were divided into 4 quartiles. Logistic regression analysis was used to examine the association of demographic information of participants with mean scores of quartiles. ANOVA analysis was used to compare the mean scores of quartiles. RESULTS: A total of 514 women completed the questionnaire, with a mean age of 35.46 (±12.53). Current smokers were 6.2%, and 34.6% had a family history of heart disease. The proportion of diabetes, hypertension, hypercholesterolemia, and overweight/obesity were 15.6%, 19.3%, 14.4%, & 21.6% respectively. The mean score for awareness was 12.87 (+ 3.26). Women who had lower income and who were at younger age were more likely to score low in awareness. CONCLUSION: Women illustrated a fair level of awareness of CVD and its related risk factors. Increasing women awareness of CVD through educational programs, targeted toward women at risk, assists in disease prevention and help to improve treatment plans.

scholarly journals THE EPIDEMIOLOGICAL PATTERN OF FACTORS ASSOCIATED WITH ISCHEMIC STROKE IN PATIENTS UNDER 50 YEARS OF AGE: A CROSS-SECTIONAL STUDY

2021 ◽  
Vol 11 (3) ◽  
pp. 9-13
Author(s):  
Nourollah Ramroodi ◽  
Seyed Mehdi Hashemi ◽  
Mehrdad Ramroudi
Keyword(s):  
Blood Pressure ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
History Of ◽  
Epidemiological Pattern ◽  
The Mean

Objective: The aim of the present study was to investigate the epidemiological pattern of factors associated with ischemic stroke among patients under 50 years old. Methods: The present cross-sectional study was performed on 197 Stroke patients. Individuals with confirmed ischemic stroke based on of CT scan were included in the study. Demographic information included age, sex, history of smoking, place of residence, season of disease incidence, history of contraceptive use in women, history of hypertension, having high blood pressure at the onset of diabetes, hyperlipidemia, heart disease and patient weight. Finally, the collected data was analyzed using SPSS ver. 22. Results: The mean age of participants was 40.18 years. The mean weight, height, body mass index (BMI) were 79.83, 168.63, and 28.12, respectively. A total of 60.4% of the participants were male and 39.6% were female. Moreover, 66.9% were urban residents, 38.6% had complications in winter, 67% were smokers, and 50% used contraceptives. The history of hypertension, diabetes, hyperlipidemia, and heart disease was seen in 69%, 49.7, 66%, and 73.6% of cases, respectively. Also, 53.8% of patients had high blood pressure upon admission. Conclusion: The present study showed that a history of heart disease and a history of hypertension in the past and nicotine use are very common in people with stroke. Considering the above mentioned epidemiological factors, it is recommended to prioritize the mentioned factors when identifying new cases

scholarly journals Prevalence and Associated Factors of Hypertension among Civil Servants Working in Arba Minch Town, South Ethiopia

2016 ◽  
Vol 5 (4) ◽  
pp. 375
Author(s):  
Aschenaki Kalssa ◽  
Gistane Ayele ◽  
Alemu Tamiso ◽  
Tadele Girum
Keyword(s):  
Cross Sectional Study ◽  
Civil Servants ◽  
Global Public Health ◽  
Cross Sectional ◽  
History Of ◽  
Public Health Challenge ◽  
Family History Of Hypertension ◽  
The Mean ◽  
Study Participants ◽  
Structured Questionnaire

Despite Hypertension is a global public health challenge and a leading modifiable risk factor for cardiovascular disease and death attention was not given in developing countries. Therefore measuring the prevalence and identifying predictors of Hypertension is very important. Institution based cross sectional study design was employed from March–April, 2016 by taking 319 randomly selected civil servants working in in Arba Minch town. Data was collected using structured questionnaire and standardized instruments for physical examination by 5 trained nurses. SPSS version 20 was used for data analysis. Bi-variable and Multivariate logistic regression was employed for analysis of risk factors. The mean SBP and DBP of study participants were 120.87 + 14.15 mmHg and 80.28 + 8.8 mmHg, respectively. The prevalence of hypertension was found to be 27.8% (95% CI = 22.9-32.7%). Civil servants of age 50 years and above [AOR = 13.3], age 40-49 years [AOR = 5], age 30-39 years [AOR = 3.5], abdominal obesity [AOR=12.2], general obesity [AOR = 4.2], stress status [AOR = 12.3], current alcohol drink [AOR = 3.3], ex-drinker [AOR = 8.9] and family history of hypertension [AOR = 5.6] were found to be significantly associated with hypertension. The prevalence indicates that it is hidden epidemic in this population; therefore for screening and risk reduction program are needed.

scholarly journals Prevalence and Associated Factors of Hypertension among Civil Servants Working in Arba Minch Town, South Ethiopia

2016 ◽  
Vol 5 (4) ◽  
pp. 375
Author(s):  
Aschenaki Kalssa ◽  
Gistane Ayele ◽  
Alemu Tamiso ◽  
Tadele Girum
Keyword(s):  
Cross Sectional Study ◽  
Civil Servants ◽  
Global Public Health ◽  
Cross Sectional ◽  
History Of ◽  
Public Health Challenge ◽  
Family History Of Hypertension ◽  
The Mean ◽  
Study Participants ◽  
Structured Questionnaire

Despite Hypertension is a global public health challenge and a leading modifiable risk factor for cardiovascular disease and death attention was not given in developing countries. Therefore measuring the prevalence and identifying predictors of Hypertension is very important. Institution based cross sectional study design was employed from March–April, 2016 by taking 319 randomly selected civil servants working in in Arba Minch town. Data was collected using structured questionnaire and standardized instruments for physical examination by 5 trained nurses. SPSS version 20 was used for data analysis. Bi-variable and Multivariate logistic regression was employed for analysis of risk factors. The mean SBP and DBP of study participants were 120.87 <span style="text-decoration: underline;">+</span> 14.15 mmHg and 80.28 <span style="text-decoration: underline;">+</span> 8.8 mmHg, respectively. The prevalence of hypertension was found to be 27.8% <br /> (95% CI = 22.9-32.7%). Civil servants of age 50 years and above <br /> [AOR = 13.3], age 40-49 years [AOR = 5], age 30-39 years [AOR = 3.5], abdominal obesity [AOR=12.2], general obesity [AOR = 4.2], stress status [AOR = 12.3], current alcohol drink [AOR = 3.3], ex-drinker [AOR = 8.9] and family history of hypertension [AOR = 5.6] were found to be significantly associated with hypertension. The prevalence indicates that it is hidden epidemic in this population; therefore for screening and risk reduction program are needed.

scholarly journals Are presbyopes willing to pay for spectacles? A Cross-sectional study’’

2019 ◽  
Author(s):  
Haile Woretaw Alemu ◽  
Anthony Carlson
Keyword(s):  
Willingness To Pay ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Monthly Income ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
History Of ◽  
The Mean ◽  
South Gondar

Abstract Objective Cross-sectional study design were used to assess willingness to pay for spectacles among south Gondar presbyopic population.Results Of the total 322 people participating in the study, only 53.4% (172) were experienced by spectacles users. The median gross monthly income of participants was US$ 75.0 (ranged US$ 7.1 - 321.4) and the mean amount of money willing to pay for a pair of spectacles was US$ 17.9 (ranged US$ 1.1-107.1). Participants who were willing to pay US$ 12.5 for a pair of spectacles from a government optical accounted for 63.0% (95% CI: 57.8-68.3), while those willing to pay the minimum international pair of spectacle price US$ 5.6 were accounted 73.9% (95% CI: 68.9-79.2%) and spectacle from local private optical price US$ 17.8 accounted 46.6% (95% CI: 40.4-52.2). Multivariate logistic regression analysis indicated factors such as age (P=0.049), occupation (0.001), monthly income (0.001) and history of the previous spectacle wear (0.005) to be significantly associated with willingness to pay for a pair of spectacles. Public willingness to pay for a pair of spectacle has to be supported with the accessible provision of spectacles to increase spectacle coverage among presbyopic individuals.

scholarly journals Risk Factors of Esophageal Bleeding in Children with Various Etiologies of Liver Cirrhosis – A Single-Center Report from Iran

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Seyed Mohsen Dehghani ◽  
Zeinab Rashidinia ◽  
Iraj Shahramian ◽  
Ali Bazi ◽  
Amir Saeed ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Clinical Importance ◽  
Cross Sectional Study ◽  
Meld Score ◽  
Cross Sectional ◽  
Esophageal Bleeding ◽  
Significant Difference ◽  
History Of ◽  
The Mean

Abstract Esophageal bleeding is a common complication in patients with liver cirrhosis. In thee present study, our aim was to divulge major factors predicting esophageal bleeding in Iranian children with liver cirrhosis. This was a cross-sectional study including 101 children < 18 years old referred to the Pediatric Endoscopy Unit of Nemazee Teaching Hospital of Shiraz from 2014 until 2016. Children with esophageal varices were included. The patients were divided into two groups including those with and without history of esophageal bleeding. Statistical methods were performed in SPSS 16 software. There were 49 boys and 52 girls. The mean age was 7.74±5.26 years old. A history of esophageal bleeding was observed in 53 (52.4%). In univariate analyses, significant relationships were found between esophageal bleeding and varices size (P=0.001), Child-Pugh score (P=0.01), age of bleeding initiation (P<0.001), serum creatinine (P=0.01), and serum sodium (P=0.002). There was no statistically significant difference in the mean of PELD/MELD score among children with (12.34±12) and without (14.61±17.51) history of esophageal bleeding (P=0.5). Among various etiologies of cirrhosis, a significant association was observed between autoimmune hepatitis and the history of esophageal bleeding (P=0.01). Regarding the clinical importance of esophageal bleedings in children with liver cirrhosis, it is recommended to further divulge the risk factors pre-disposing to this event.

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