Composite Adenomatoid Tumor and Myelolipoma of Adrenal Gland: Report of 2 Cases

2008 ◽  
Vol 132 (2) ◽  
pp. 265-267
Author(s):  
Elizabeth R. Timonera ◽  
Maria Emilia Paiva ◽  
Jose Manuel Lopes ◽  
Catarina Eloy ◽  
Theodore van der Kwast ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Incidental Findings ◽  
Adrenal Glands ◽  
Adenomatoid Tumor

Abstract Adenomatoid tumor and myelolipoma are benign, hormonally inactive tumors that are often incidental findings in the adrenal glands. Myelolipoma is more common than adenomatoid tumor in this location but both are rare, and as yet, the pathogenesis of both remains unclear. We report 2 cases of composite adenomatoid tumor and myelolipoma, incidentally found in the adrenal gland on investigation for other diseases. To our knowledge, composite adenomatoid tumor and myelolipoma of adrenal gland has not been previously reported.

Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland

2017 ◽  
Vol 68 (9) ◽  
pp. 2014-2017
Author(s):  
Jelena Savici ◽  
Oana Maria Boldura ◽  
Cornel Balta ◽  
Diana Brezovan ◽  
Florin Muselin ◽  
...  
Keyword(s):  
Drinking Water ◽  
Adrenal Gland ◽  
Hexavalent Chromium ◽  
Structural Damage ◽  
Hypericum Perforatum ◽  
Adrenal Glands ◽  
Expression Level ◽  
Apoptotic Pathway ◽  
Hypericum Perforatum L ◽  
Induction Of Apoptosis

This study was carried out to test the possibility of hexavalent chromium administration through drinking water to induce the structural damage in rat�s adrenal glands and the possibility of Hypericum perforatum extract to faith against chromium aggression. Chromium induced cellular stress was determined by the expression level assessment of the Bcl2 genes family, known to modulate the apoptotic pathway. Obtained results showed that exposure to chromium altered adrenal glands morphology, by induction of apoptosis. When Hypericum perforatum extract was administered expression level of Bcl2 genes and histological lesions in adrenal glands were significantly reduced.

UTILIZATION OF [26-14C]CHOLESTEROL BY HUMAN FOETAL ADRENAL GLANDS IN VITRO

1978 ◽  
Vol 79 (3) ◽  
pp. 393-394 ◽  
Author(s):  
R. GUNASEGARAM ◽  
K. L. PEH ◽  
P. C. T. CHEW ◽  
S. M. M. KARIM ◽  
S. S. RATNAM
Keyword(s):  
Adrenal Gland ◽  
Steroid Hormones ◽  
Adrenal Glands ◽  
De Novo ◽  
Obstetrics And Gynaecology ◽  
Perfusion Studies

Department of Obstetrics and Gynaecology, University of Singapore, Kandang Kerbau Hospitalfor Women, Singapore 8, Republic of Singapore (Received 3 May 1978) From the previous studies of Bloch & Benirschke (1959, 1962) and Plotz, Kabara, Davis, LeRoy & Gould (1968) it appears that at mid-term, human foetal adrenal glands are capable of synthesizing C21- and C19-steroids de novo from acetate and cholesterol. Villee, Engel, Loring & Villee (1961), however, incubated slices and homogenates of foetal adrenal gland with [2-14C]acetate or [4-14C]cholesterol and could not demonstrate the incorporation of radioactivity into these steroids. Moreover, perfusion studies by three groups of investigators indicated only minute conversions of the same radioactive substrates into neutral steroids in the foetal adrenal glands (Solomon, Bird, Ling, Iwamiya & Young, 1967; Telegdy, Weeks, Archer, Wiqvist & Diczfalusy, 1970a; Telegdy, Weeks, Lerner, Stakemann & Diczfalusy, 1970b). It is widely believed that steroid hormones are normally synthesized from acetate via

scholarly journals Specificity of action of adrenocorticotrophin in vitro on ascorbate transport in rat adrenal glands

1970 ◽  
Vol 118 (2) ◽  
pp. 283-289 ◽  
Author(s):  
M. Clayman ◽  
D. Tsang ◽  
A. F. De Nicola ◽  
R. M. Johnstone
Keyword(s):  
Adrenal Gland ◽  
Transport System ◽  
Adrenal Glands ◽  
Ascorbate Transport

The inhibition of ascorbate transport by rat adrenal quarters in response to steroidogenesis in vitro was shown to be highly specific with respect to tissue, substrate and steroidogenic agent. The transport system in vitro is capable of net accumulation of ascorbate. The evidence is consistent with the conclusion that ascorbate `depletion' in the adrenal gland is due to a specific block by corticoids of the uptake of ascorbate.

scholarly journals EFFECT OF MOBILE PHONE RADIATION ON ADRENAL GLAND OF MALE ALBINO RATS

2020 ◽  
Vol 28 (1) ◽  
Author(s):  
Shalini Gupta ◽  
Shilpi Jain ◽  
Satyam Khare ◽  
Prateek Gautam
Keyword(s):  
Adrenal Gland ◽  
Mobile Phone ◽  
Radiation Exposure ◽  
Mobile Phones ◽  
Adrenal Glands ◽  
Cellular Level ◽  
Control Group ◽  
Albino Rats ◽  
Hormonal Changes ◽  
Mobile Phone Radiation

Introduction: The tremendous growth in telecommunication world has increased the number of mobile phone users to many folds. The benefits of cell phones are just half the picture. The other half may be a darker one. The main aim of this study is to observe the effect of electromagnetic radiation being emitted by mobile phones on adrenal gland microanatomy and the hormones released by the gland on male albino rats. Materials and methods: Forty-two male albino rats of Spargue-Dawley species were divided into two equal groups. The experimental group rats were exposed to mobile phone radiation operating at 900 MHz while the control group rats were not. At the end of every two months, seven rats were sacrificed to analyse histological and hormonal changes. Results: No changes were seen at the cellular level of the adrenal glands even after six months of radiation exposure. Hormonal assay showed a variation in the cortisol levels of the rats but the changes were within normal range. Conclusions: Lack of appreciable changes in the cellular morphology and hormonal levels even after six months of radiation exposure signify that the adrenal glands are not affected by exposure to mobile phones.

scholarly journals Ultrastructure of the adrenal gland of paca (Cuniculus paca, Linnaeus, 1766) in captivity

2021 ◽  
Vol 15 (3) ◽  
pp. 203-208
Author(s):  
Sérgio Pinter Garcia Filho ◽  
Leandro Luis Martins ◽  
Paulo Fernandes Marcusso ◽  
Tais Harumi de Castro Sasahara ◽  
Márcia Rita Fernandes Machado
Keyword(s):  
Electron Microscopy ◽  
Adrenal Gland ◽  
Adrenal Glands ◽  
Comparative Anatomy ◽  
The Body ◽  
Cortical Region ◽  
Lateral Incision ◽  
Transmission Electron ◽  
In Captivity ◽  
Microscopy Techniques

Lowland paca (Cuniculus paca, Linnaeus, 1766) is a medium-sized rodent that belongs to the Brazilian fauna. Yet little information on its morphology is found in the specialized literature. Thus, the objective of the work was to study the morphology of the adrenal gland of paca by means of microscopic ultrastructure analysis. The adrenal gland secretes specialized substances in the body which promote biological functions of great importance and will provide valuable information to studies in comparative anatomy. Two (2) adult lowland pacas were used, male and female. Soon after death, the animals were positioned in the supine position; their abdominal cavities were opened by pre-retro umbilical and lateral incision followed by folding of the abdominal walls to expose the glands. The adrenal glands were removed; fragments were collected, fixed and prepared for ultrastructure observations using scanning electron microscopy and transmission electron microscopy techniques. It was observed that the adrenal glands of the paca have divisions as well as the limits of the cortical and medullary region, as well as the subdivisions of the glomerulosa, fasciculated and reticulated areas of the cortical region as in other rodents. An ultrastructure of cells and their components also showed a lot of similarity to that already demonstrated in different rodents.

scholarly journals Value of Radiomics Features From Adrenal Gland and Periadrenal Fat in CT Images for Predicting COVID-19 Prognosis

2021 ◽  
Author(s):  
Mudan zhang ◽  
Xuntao Yin ◽  
Wuchao Li ◽  
Yan Zha ◽  
Xianchun Zeng ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Adrenal Glands ◽  
Endocrine System ◽  
Ct Images ◽  
Threshold Probability ◽  
Test Set ◽  
Clinical Model ◽  
Disease Prognosis ◽  
Independent Test ◽  
Test Sets

Abstract Background: Endocrine system plays an important role in infectious disease prognosis. Our goal is to assess the value of radiomics features extracted from adrenal gland and periadrenal fat CT images in predicting disease prognosis in patients with COVID-19. Methods: A total of 1,325 patients (765 moderate and 560 severe patients) from three centers were enrolled in the retrospective study. We proposed a 3D cascade V-Net to automatically segment adrenal glands in onset CT images. Periadrenal fat areas were obtained using inflation operations. Then, the radiomics features were automatically extracted. Five models were established to predict the disease prognosis in patients with COVID-19: a clinical model (CM), three radiomics models (adrenal gland model [AM], periadrenal fat model [PM], fusion of adrenal gland and periadrenal fat model [FM]), and a radiomics nomogram model (RN).Data from one center (1,183 patients) were utilized as training and validation sets. The remaining two (36 and 106 patients) were used as 2 independent test sets to evaluate the models’ performance. Results: The auto-segmentation framework achieved an average dice of 0.79 in the test set. CM, AM, PM, FM, and RN obtained AUCs of 0.716, 0.755, 0.796, 0.828, and 0.825, respectively in the training set, and the mean AUCs of 0.754, 0.709, 0.672, 0.706 and 0.778 for 2 independent test sets. Decision curve analysis showed that if the threshold probability was more than 0.3, 0.5, and 0.1 in the validation set, the independent-test set 1 and the independent-test set 2 could gain more net benefits using RN than FM and CM, respectively. Conclusion: Radiomics features extracted from CT images of adrenal glands and periadrenal fat are related to disease prognosis in patients with COVID-19 and have great potential for predicting its severity.

scholarly journals A Case Report of Adenomatoid Tumor of the Adrenal Gland Mimicking an Adrenal Metastasis from Sigmoid Colon Cancer

2010 ◽  
Vol 43 (4) ◽  
pp. 472-478
Author(s):  
Akio Shiomi ◽  
Yusuke Kinugasa ◽  
Syuji Saito ◽  
Yousuke Hashimoto ◽  
Hiroyuki Tomioka ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Case Report ◽  
Adrenal Gland ◽  
Sigmoid Colon ◽  
Adrenal Metastasis ◽  
Sigmoid Colon Cancer ◽  
Adenomatoid Tumor

scholarly journals Morphological features of primary cultures of adrenal cells of neonatal animals of different species

2019 ◽  
Keyword(s):  
Adrenal Gland ◽  
Cell Cultures ◽  
Adrenal Glands ◽  
Primary Cultures ◽  
Cell Monolayer ◽  
Calf Serum ◽  
Morphological Features ◽  
Primary Cell ◽  
Endocrine Gland ◽  
Primary Cell Cultures

The adrenal gland is an endocrine gland, which in the process of organogenesis is formed from ecto- and mesoderm derivatives. The mechanisms that make cell types of different origins unite, migration routes, and cell interactions are still not fully understood. One of the tools for studying these mechanisms is the primary cell culture obtained from the adrenal gland. The aim of our work was to compare the morphological features of primary cell cultures of model animals belonging to different orders – pigs, rabbits and mice in vitro under various cultivation conditions (growth surface pattern, presence of growth factors), as well as developing methodological approaches for obtaining and maintaining primary cultures of adrenal cell of neonatal animals. Cultivation was performed under standard conditions of temperature and humidity, carbon dioxide concentration, on culture surfaces with normal and reduced adhesiveness in a nutrient medium DMEM enriched with 10% fetal calf serum (FTS) or growth supplements B-27 and FGF. It was established that cell cultures of adrenal neonatal rabbits and piglets that were cultured under conditions of normal adhesion and using FCS had a heterogeneous composition, and were presented as a monolayer consisting of cells of several morphological types, and multicellular spheroids (MS). When cultivated on the surface with reduced adhesive properties in cultures of adrenal glands of piglets and rabbits, a cell monolayer was not formed, but flotation MCs were formed. After transferring MCs of both species to the adhesive culture surface on day 14, cell eviction, their migration from the MCs and formation of a monolayer are observed. Similar stages in the development of primary cell cultures derived from rabbits and piglets suggest the existence of a universal cellular composition in the neonatal adrenal glands of these species and allow applying the same approaches to the primary cultures derived from them. Unlike other studied species, monolayer and MS formation does not occur in cell cultures of mouse neonatal adrenal glands. Cultures consist of single attached and floating cells and small cell aggregates.

THE EFFECT OF ADRENOCORTICOTROPHIN ON THE NUCLEIC ACID METABOLISM OF THE RAT ADRENAL GLAND

1965 ◽  
Vol 32 (3) ◽  
pp. 303-312 ◽  
Author(s):  
R. C. IMRIE ◽  
T. R. RAMAIAH ◽  
F. ANTONI ◽  
W. C. HUTCHISON
Keyword(s):  
Nucleic Acid ◽  
Adrenal Gland ◽  
Dna Content ◽  
Adrenal Glands ◽  
Acid Metabolism ◽  
Female Rats ◽  
Nucleic Acid Metabolism ◽  
Prolonged Administration ◽  
Total Rna ◽  
Rna And Dna

SUMMARY Treatment of female rats with adrenocorticotrophin (ACTH) increased the RNA content of the adrenal glands progressively during a period of 3 days, the DNA content increased only after prolonged administration. By contrast, ACTH caused a decrease in the uptake of [32P]orthophosphate into the total RNA of the gland and into most of the RNA fractions of the subcellular components. A method of analysis for RNA and DNA based on the Schmidt-Thannhauser procedure has been evolved which eliminates extraction of nucleic acid by lipid solvents.

The Endocrine System: Adrenal Glands

2017 ◽  
Author(s):  
Abbas Al-Kurd ◽  
Haggi Mazeh
Keyword(s):  
Adrenal Gland ◽  
Key Words ◽  
Patient Group ◽  
Clinical Relevance ◽  
Perioperative Management ◽  
Adrenal Glands ◽  
Preoperative Evaluation ◽  
Endocrine System ◽  
Anatomy And Physiology ◽  
Complicated Patient

The adrenal glands represent an essential component of the endocrine system, and their failure can have catastrophic consequences to several aspects of bodily homeostasis. Each adrenal gland can be divided into two different endocrine components, the cortex and the medulla, each with distinct functions. This in-depth review of normal adrenal embryology, anatomy, and physiology also emphasizes the clinical relevance of various irregularities in adrenal functioning. Every surgeon attempting to manage adrenal diseases is expected to be familiar with the detailed pathophysiology of these conditions because such an understanding is essential for sound preoperative evaluation and perioperative management of this potentially complicated patient group.  This review contains 4 figures, 1 table, and 70 references. Key words: adrenal, adrenal glands, adrenal pathophysiology, adrenal physiology, anatomy of adrenal glands, cortex, embryology, endocrine system, medulla

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