Effects of endurance training on exhaustive exercise-induced oxidative stress markers

The effects of preexercise photobiomodulation therapy (PBMT) to enhance performance, accelerate recovery, and attenuate exercise-induced oxidative stress were still not fully investigated, especially in high-level athletes. The aim of this study was to evaluate the effects of PBMT (using infrared low-level laser therapy) applied before a progressive running test on functional aspects, muscle damage, and inflammatory and oxidative stress markers in high-level soccer players. A randomized, triple-blind, placebo-controlled crossover trial was performed. Twenty-two high-level male soccer players from the same team were recruited and treated with active PBMT and placebo. The order of interventions was randomized. Immediately after the application of active PBMT or placebo, the volunteers performed a standardized high-intensity progressive running test (ergospirometry test) until exhaustion. We analyzed rates of oxygen uptake (VO2 max), time until exhaustion, and aerobic and anaerobic threshold during the intense progressive running test. Creatine kinase (CK) and lactate dehydrogenase (LDH) activities, levels of interleukin-1β (IL-1-β), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α), levels of thiobarbituric acid (TBARS) and carbonylated proteins, and catalase (CAT) and superoxide dismutase (SOD) activities were measured before and five minutes after the end of the test. PBMT increased the VO2 max (both relative and absolute values—p<0.0467 and p<0.0013, respectively), time until exhaustion (p<0.0043), time (p<0.0007) and volume (p<0.0355) in which anaerobic threshold happened, and volume in which aerobic threshold happened (p<0.0068). Moreover, PBMT decreased CK (p<0.0001) and LDH (p<0.0001) activities. Regarding the cytokines, PBMT decreased only IL-6 (p<0.0001). Finally, PBMT decreased TBARS (p<0.0001) and carbonylated protein levels (p<0.01) and increased SOD (p<0.0001)and CAT (p<0.0001) activities. The findings of this study demonstrate that preexercise PBMT acts on different functional aspects and biochemical markers. Moreover, preexercise PBMT seems to play an important antioxidant effect, decreasing exercise-induced oxidative stress and consequently enhancing athletic performance and improving postexercise recovery. This trial is registered with Clinicaltrials.gov NCT03803956.

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Biochemical changes in oxidative stress markers following endurance training and consumption of purslane seed in rats with hydrogen peroxide-induced toxicity

Sport Sciences for Health ◽

10.1007/s11332-018-0501-y ◽

2018 ◽

Vol 15 (1) ◽

pp. 133-139 ◽

Cited By ~ 3

Author(s):

Rahman Soori ◽

Valiollah Shahedi ◽

Ali Akbarnejad ◽

Siroos Choobineh

Keyword(s):

Oxidative Stress ◽

Hydrogen Peroxide ◽

Endurance Training ◽

Biochemical Changes ◽

Oxidative Stress Markers ◽

Stress Markers ◽

Purslane Seed

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Circulating leukocyte heat shock protein 70 (HSP70) and oxidative stress markers in rats after a bout of exhaustive exercise

Stress ◽

10.1080/10253890600772211 ◽

2006 ◽

Vol 9 (2) ◽

pp. 107-115 ◽

Cited By ~ 16

Author(s):

J. M. F. Antunes-Neto ◽

M. H. Toyama ◽

E. M. Carneiro ◽

A. C. Boschero ◽

L. Pereira-da-Silva ◽

...

Keyword(s):

Oxidative Stress ◽

Heat Shock ◽

Heat Shock Protein ◽

Heat Shock Protein 70 ◽

Exhaustive Exercise ◽

Oxidative Stress Markers ◽

Stress Markers ◽

And Oxidative Stress

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Changes in Oxidative Stress Markers and Biological Markers of Muscle Injury with Aging at Rest and in Response to an Exhaustive Exercise

PLoS ONE ◽

10.1371/journal.pone.0090420 ◽

2014 ◽

Vol 9 (3) ◽

pp. e90420 ◽

Cited By ~ 45

Author(s):

Mohamed Amine Bouzid ◽

Omar Hammouda ◽

Regis Matran ◽

Sophie Robin ◽

Claudine Fabre

Keyword(s):

Oxidative Stress ◽

Biological Markers ◽

Muscle Injury ◽

Exhaustive Exercise ◽

Oxidative Stress Markers ◽

Stress Markers ◽

And Biological Markers

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Oxidative Stress Markers After a Race in Professional Cyclists

International Journal of Sport Nutrition and Exercise Metabolism ◽

10.1123/ijsnem.2014-0090 ◽

2015 ◽

Vol 25 (2) ◽

pp. 171-178 ◽

Cited By ~ 6

Author(s):

Alfredo Córdova ◽

Antoni Sureda ◽

María L. Albina ◽

Victoria Linares ◽

Montse Bellés ◽

...

Keyword(s):

Oxidative Stress ◽

Glutathione Peroxidase ◽

Peroxidase Activity ◽

Acute Exercise ◽

Oxidative Stress Markers ◽

Glutathione Peroxidase Activity ◽

Stress Markers ◽

Exercise Induced ◽

Induced Changes ◽

Plasma Malondialdehyde

The aim was to determine the levels and activities of the oxidative stress markers in erythrocytes, plasma, and urine after a flat cyclist stage. Eight voluntary male professional trained-cyclists participated in the study. Exercise significantly increased erythrocyte, leukocyte, platelet, and reticulocyte counts. The exercise induced significant increases in the erythrocyte activities of catalase (19.8%) and glutathione reductase (19.2%), while glutathione peroxidase activity decreased significantly (29.3%). Erythrocyte GSSG concentration was significantly increased after exercise (21.4%), whereas GSH was significantly diminished (20.4%). Erythrocyte malondialdehyde levels evidenced a significant decrease 3 h after finishing the stage (44.3%). Plasma malondialdehyde, GSH and GSSG levels significantly decreased after 3 hr recovery (26.8%, 48.6%, and 31.1%, respectively). The exercise significantly increased the F2-isoprostane concentration in urine from 359 ± 71 pg/mg creatinine to 686 ± 139 pg/mg creatinine. In conclusion, a flat cycling stage induced changes in oxidative stress markers in erythrocytes, plasma, and urine of professional cyclists. Urine F2-isoprostane is a more useful biomarker for assessing the effects of acute exercise than the traditional malondialdehyde measurement.

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Effects of Exercise Training under Hyperbaric Oxygen on Oxidative Stress Markers and Endurance Performance in Young Soccer Players: A Pilot Study

Journal of Nutrition and Metabolism ◽

10.1155/2016/5647407 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 4

Author(s):

Carlos Burgos ◽

Carlos Henríquez-Olguín ◽

David Cristóbal Andrade ◽

Rodrigo Ramírez-Campillo ◽

Oscar F. Araneda ◽

...

Keyword(s):

Oxidative Stress ◽

Antioxidant Capacity ◽

Endurance Training ◽

Hyperbaric Oxygen ◽

Endurance Performance ◽

Soccer Players ◽

Peak Power Output ◽

Oxidative Stress Markers ◽

Stress Markers ◽

Before And After

The aim of the present study was to determine the effects of three weeks of hyperbaric oxygen (HBO2) training on oxidative stress markers and endurance performance in young soccer players. Participants (18.6±1.6 years) were randomized into hyperbaric-hyperoxic (HH) training (n=6) and normobaric normoxic (NN) training (n=6) groups. Immediately before and after the 5th, 10th, and 15th training sessions, plasma oxidative stress markers (lipid hydroperoxides and uric acid), plasma antioxidant capacity (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid [TROLOX]), arterial blood gases, acid-base balance, bases excess (BE), and blood lactate analyses were performed. Before and after intervention, maximal oxygen uptake (VO2max) and peak power output (PPO) were determined. Neither HH nor NN experienced significant changes on oxidative stress markers or antioxidant capacity during intervention. VO2max and PPO were improved (moderate effect size) after HH training. The results suggest that HBO2 endurance training does not increase oxidative stress markers and improves endurance performance in young soccer players. Our findings warrant future investigation to corroborate that HBO2 endurance training could be a potential training approach for highly competitive young soccer players.

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Relation between oxidative stress markers and antioxidant endogenous defences during exhaustive exercise

Free Radical Research ◽

10.1080/10715760500177500 ◽

2005 ◽

Vol 39 (12) ◽

pp. 1317-1324 ◽

Cited By ~ 101

Author(s):

Antoni Sureda ◽

Pedro Tauler ◽

Antoni Aguiló ◽

Nuria Cases ◽

Emilia Fuentespina ◽

...

Keyword(s):

Oxidative Stress ◽

Exhaustive Exercise ◽

Oxidative Stress Markers ◽

Stress Markers

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l-Arginine supplementation improves antioxidant defenses through l-arginine/nitric oxide pathways in exercised rats

Journal of Applied Physiology ◽

10.1152/japplphysiol.00225.2013 ◽

2013 ◽

Vol 115 (8) ◽

pp. 1146-1155 ◽

Cited By ~ 21

Author(s):

Lingling Shan ◽

Bin Wang ◽

Guizhen Gao ◽

Wengen Cao ◽

Yunkun Zhang

Keyword(s):

Oxidative Stress ◽

Nitric Oxide ◽

Physical Exercise ◽

Endurance Training ◽

Antioxidant Defense ◽

Exhaustive Exercise ◽

Antioxidant Defenses ◽

Sedentary Control ◽

Antioxidant Defense Capacity ◽

Exercise Induced

l-Arginine (l-Arg) supplementation has been shown to enhance physical exercise capacity and delay onset of fatigue. This work investigated the potential beneficial mechanism(s) of l-Arg supplementation by examining its effect on the cellular oxidative and nitrosative stress pathways in the exercised rats. Forty-eight rats were randomly divided into six groups: sedentary control; sedentary control with l-Arg treatment; endurance training (daily swimming training for 8 wk) control; endurance training with l-Arg treatment; an exhaustive exercise (one time swimming to fatigue) control; and an exhaustive exercise with l-Arg treatment. l-Arg (500 mg/kg body wt) or saline was given to rats by intragastric administration 1 h before the endurance training and the exhaustive swimming test. Expression levels and activities of the l-Arg/nitric oxide (NO) pathway components and parameters of the oxidative stress and antioxidant defense capacity were investigated in l-Arg-treated and control rats. The result show that the l-Arg supplementation completely reversed the exercise-induced activation of NO synthase and superoxide dismutase, increased l-Arg transport capacity, and increased NO and anti-superoxide anion levels. These data demonstrate that l-Arg supplementation effectively reduces the exercise-induced imbalance between oxidative stress and antioxidant defense capacity, and this modulation is likely mediated through the l-Arg/NO pathways. The findings of this study improved our understanding of how l-Arg supplementation prevents elevations of reactive oxygen species and favorably enhances the antioxidant defense capacity during physical exercise.

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