scholarly journals Allelopathic effects of alkaloid fraction of Crotalaria retusa Linn on growth and some biochemical parameters of bean seedlings (Phaseolus vulgaris

2018 ◽  
Vol 10 (1) ◽  
pp. 1-9 ◽  
Author(s):  
M. Ogunsusi ◽  
A. O. Akinlalu ◽  
I. J. Komolafe ◽  
O. O. Oyedapo

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Heliton Patrick Cordovil Brígido ◽  
Everton Luiz Pompeu Varela ◽  
Antônio Rafael Quadros Gomes ◽  
Mirian Letícia Carmo Bastos ◽  
Andre de Oliveira Feitosa ◽  
...  

AbstractThis study investigated the acute and subacute toxicity of the ethanolic extract (EE) and alkaloid fraction (FA) from A. nitidum. The EE was obtained from trunk bark with ethanol, FA was obtained from the fractionation of EE. To test the acute toxicity, mice were divided into four groups, and the negative controls received water or aqueous solution of dimethyl sulfoxide, whereas the others received EE or FA (2000 mg/kg, orally, single dose). The same controls were used in the subacute trial. However, the animals were treated for 28 days, and the dose used was 1000 mg/kg per day of EE and FA. Daily clinical evaluations of the animals were performed. At the end of the experiment, hematological, biochemical, and histopathological assessments (liver, lung, heart, and kidney) were performed. In the acute and subacute toxicity studies, mice treated with EE and FA did not show any clinical changes, there were no changes in weight gain, hematological and biochemical parameters compared to the control groups (p > 0.05). In the histopathological examination, there was no abnormality in the organs of the treated animals. Therefore, EE and FA did not produce toxic effects in mice after acute and subacute treatment.



2017 ◽  
Vol 8 (5) ◽  
pp. 577-585 ◽  
Author(s):  
M. Zayed ◽  
S. Elkafafi ◽  
Amina Zedan ◽  
Sherifa Dawoud


2012 ◽  
Vol 51 (No. 4) ◽  
pp. 145-155 ◽  
Author(s):  
J. Psotova ◽  
R. Vecera ◽  
A. Zdarilova ◽  
E. Anzenbacherova ◽  
P. Kosina ◽  
...  

The subchronic safety of sanguiritrin, a mixture of sanguinarine (SA) and chelerythrine (CHE) quaternary benzo[c]phenanthridine alkaloids (QBA), obtained from Macleaya cordata was assessed. Rats were fed a&nbsp;diet containing 120 ppm sanguiritrin (100 ppm QBA) for 109 days. The feed consumption and the animal weight were monitored. The content of QBA in selected tissues and plasma was determined using HPLC. It was evidenced that 2% of QBA were absorbed through the GIT while 98% were excreted in the feces. In plasma, bilirubin, urea, creatinine, glomerular filtration, AST, ALT, GMT, ALP and total antioxidant capacity were determined. In liver, GSH level, lipoperoxidation products, SOD and GPx activities and total amount of cytochrome P450 were evaluated. Damage to nuclear DNA was assessed; a <sup>32</sup>P-postlabeling assay proved that no DNA-adducts were detected in nuclear and mitochrondrial DNA in liver. No adverse effects were observed on rat organism. QBA had no influence on the gut mucosal epithelium, liver tissue and any biochemical parameters tested. Oxidative stress was not manifested during the experiment.



Author(s):  
J.P.G. Rigon ◽  
S. Capuani ◽  
M.R. Cherubin ◽  
A.D. Wastowski ◽  
G.M. Rosa


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Hudson C. Laizer ◽  
Musa N. Chacha ◽  
Patrick A. Ndakidemi

Weeds with allelopathic effect have been reported to cause significant damage in agriculture particularly in smallholder farming systems. This study assessed the allelopathic effects of different concentrations of crude extract of a noxious weed Sphaeranthus suaveolens on seed germination and seedling growth of Phaseolus vulgaris and Oryza sativa by examining germination, seedling height, and total chlorophyll content after seven and fourteen days of crude extract treatment, respectively. Results showed that seed germination and seedling growth were significantly ( p < 0.001 ) decreased with increase in concentration of crude extract, signifying concentration dependency. Highest concentration (100%) of S. suaveolens crude extracts resulted in 90% and 100% inhibition of P. vulgaris and O. sativa seed germination, respectively. Chlorophyll content, fresh weight, and root and shoot length of both P. vulgaris and O. sativa were also significantly ( p < 0.001 ) affected by highest concentration (100%) of S. suaveolens crude extracts. Results from this study suggest that the extract of S. suaveolens contains water-soluble allelochemicals which significantly reduce growth and productivity of P. vulgaris and O. sativa.



Author(s):  
L. Ivashko ◽  
V. Dmytrik ◽  
Ya. Raetska

BIOCHEMICAL PARAMETERS OF THE RATS WITH ESOPHAGEUS BURN TREATED WITH AQUESOUS EXTRACT OF PHASEOLUS VULGARIS PODS



Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3346
Author(s):  
Sahbanathul Missiriya Jalal ◽  
Abdulrahman Abdulhadi Alsultan ◽  
Hala Hazam Alotaibi ◽  
Ester Mary ◽  
Abeer Abbas Ibrahim Alabdullatif

The study purpose was to investigate the effect of Phaseolus Vulgaris (PV) on urinary biochemical parameters among patients with kidney stones. We conducted a randomized controlled study among 60 patients with kidney stones (size < 10 mm) in the nephrology unit of both government and private hospitals, Al-Ahsa. Urinary volume, calcium, magnesium, potassium, oxalate, uric acid, and power of hydrogen (pH) were assessed before and after the intervention of giving 250 g of PV consumption as an extract thrice weekly (2.2 L to 2.5 L per week) for 6 weeks, which was compared with control. A ‘t’ test was used with the significance at 5%. Mean score of age was 44.5 ± 10.16 in PV group and 43.73 ± 9.79 in control. Four (13.3%) and two (6.7%) had family history of kidney stones. Body mass Index (BMI) mean was 26.44 ± 2.7 and 26.36 ± 2.65 in pre and post-test, respectively, which were significant (p = 0.01017). There were significant changes (p = 0.000) in urine volume from 1962 ± 152.8 to 2005 ± 148.8, calcium 205.4 ± 11.99 to 198.4 ± 12.52, potassium 44.07 ± 3.66 to 52.15 ± 4.37, oxalate 37.12 ± 5.38 to 33.02 ± 5.71, and uric acid 6.88 ± 0.7 to 6.31 ± 0.58. In conclusion, PV is effective management for the patients with kidney stones as it increases the urinary volume and enhances the elimination of small kidney stones.



2016 ◽  
Vol 05 (06) ◽  
pp. 548-551 ◽  
Author(s):  
M. Mroczek-Zdyrska ◽  
L. Tryniecki ◽  
K. Kornarzyński ◽  
S. Pietruszewski ◽  
M. Gagoś


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