The features of the accumulation of heavy metals in medicinal plant raw materials Tanacetum vulgare L. in the conditions of the Trans-Urals region of the Republic of Bashkortostan are discussed. The variation-statistical indices of the content of heavy metals in soils and in plants are calculated. Soils and plants have high coefficients of heavy metals variation, with the exception of manganese in the soil, which is characterized by moderate variability. An increased level of heavy metals mobile forms, such as Cu, Zn, Mn, Fe, Pb, Cd, has been detected in all soil samples. All selected samples had an elevated level of mobile forms. According to the degree of contamination, the studied soils were classified as permissible. In tansy plants, the concentration of trace elements-biophiles exceeded the norm in Fe 1.7–6.24, in Cd 1.3–1.7 times, and the concentrations of Cu, Zn, Mn, Pb in the aboveground and underground parts of the species remained within the normal range. It is revealed that the root system of Tanacetum vulgare L. contains higher values of the studied elements than the aerial parts. According to the intensity of absorption, the elements are arranged in the following sequence: Zn → Cd → Cu → Fe → Mn → Pb. According to the coefficient of biological accumulation in tansy, ordinary zinc and iron belong to the elements of weak accumulation, copper, manganese, lead, cadmium –to the elements of weak capture.