TECHNOLOGY FOR OBTAINING PECTIN CONCENTRATE FROM ROSEHIP FRUITS

2021 ◽  
pp. 87-90
Author(s):  
М.Ж. Кизатова ◽  
Д.А. Абдуллаева
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Raw Material ◽  
Plant Raw Materials ◽  
Plant Raw Material ◽  
Pectin Substances

Статья посвящена важности пектиновых веществ, а также расширению сферы использования лекарственного растительного сырья. В качестве лекарственного растительного сырья представлены технологии получения пектинового экстракта из плодов шиповника, которые встречаются на территории Казахстана 25 видов. Применение пектина в медицине. The article is devoted to the importance of pectin substances, as well as to the expansion of the use of medicinal plant raw materials. As a medicinal plant raw material, technologies for obtaining pectin extract from rosehip fruits, which are found in 25 species on the territory of Kazakhstan, are presented. The use of pectin in medicine

scholarly journals Development of approaches to standardization of black walnut bark

2020 ◽  
Vol 20 (1-2) ◽  
pp. 131-136
Author(s):  
Natalya I. Zimenkina ◽  
Vladimir A. Kurkin
Keyword(s):  
Medicinal Plant ◽  
Quantitative Determination ◽  
Raw Materials ◽  
Juglans Regia ◽  
Black Walnut ◽  
Juglans Nigra ◽  
Raw Material ◽  
Plant Raw Materials ◽  
Plant Raw Material

Significance. Black Walnut (Juglans nigra L.) is a species of trees of the Walnut family (Juglandaceae). This plant of the genus Walnut (Juglans L.) has not been sufficiently studied unlike other species e.g. Juglans regia L. This medicinal plant raw material is quite perspective, its preparations have antimicrobial, general tonic effect. We can use its leaves, unripe fruit, and the bark. However they are not widely used in medicine. In order to introduce the plants of the Walnut genus to the State Pharmacopoeia of the Russian Federation (RF State Pharmacopoeia), it is necessary to conduct of pharmacognostic studies, to develop product specification file to confirm the identification and quality of medicinal plant raw materials. The aim of this study is to develop a method of quantitative determination of flavonoids in the bark of the black walnut (Juglans nigra L.). Materials and methods. Material of the study was black walnut bark, stocked during the sap flow period (April) in 2018. The bark was skived up to 15 cm long and 23 cm wide. The bark was air-dried with the protection from direct sun light. The end of the drying was checked by the brittleness of the bark. Results. The methods of the quantitative determination of flavonoids in walnut bark has been developed. We used the differential spectrophotometry taking into consideration state standard sample of rutin at the analytical wavelength of 416 nm. The error of a single determination with a confidence level of 95% is 1.20%. Conclusion. We used the developed technique and analyzed a number of samples of black walnut bark. The content of total flavonoids in the plant raw material is 5.13 0.02% (as calculated on rutin). The flavonoid content should be at least 4.0%.

scholarly journals Medicinal flora of the Middle Urals – a prospective source of obtaining medicines

2021 ◽  
Vol 10 (4) ◽  
pp. 32-36
Author(s):  
A. Yu. Turyshev ◽  
V. D. Belonogova ◽  
A. A. Orlova ◽  
K. O. Sidorov ◽  
A. Yu. Skornyakova
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Quantitative Assessment ◽  
Raw Materials ◽  
The State ◽  
Raw Material ◽  
Middle Urals ◽  
The Middle Urals ◽  
Plant Raw Materials ◽  
Medicinal Flora

Introduction. Medicinal plant raw materials are one of the most important sources of herbal remedies used both for the prevention and treatment of a number of diseases [1, 2]. Even with the development of modern science and chemistry, medicinal plant raw materials are widely used in both folk and official medicine. The advantage of medicinal plants is their wide range of biological activity, low toxicity and the possibility of long-term use without significant side effects. Human economic activity has a noticeable negative effect on the condition of wild-growing plants: their stocks are decreasing, and some species disappear altogether. Today, given the high level of development of industry and agriculture, the procurement of raw materials for wild medicinal plants is not always possible. Information on the quantitative assessment of the raw material base of wild medicinal plants in the Middle Urals, the content of biologically active substances in medicinal plant raw materials is partially outdated, which determines the need for their systemic resource study and chemical-pharmacognostic study.Aim. Comprehensive assessment of the state of populations of wild medicinal plants in the Middle Urals.Materials and methods. Determination of stocks of raw materials of the studied species of medicinal plants was carried out on specific thickets according to the generally accepted method. The authenticity of the raw materials was established by a macroscopic method when collecting raw material samples. In the course of the study, samples of medicinal plant materials of 5 types were prepared. The determination and assessment of the main indicators of the good quality of medicinal plant raw materials (the content of active and extractive substances, moisture in the mass upon drying, total ash and ash insoluble in a 10% solution of hydrochloric acid) was carried out according to the methods and requirements of the State Pharmacopoeia of the Russian Federation XIV edition. In the raw materials Artemisiae absinthii herba and Leonuri herba, the amount of extractives was determined by the gravimetric method. The quantitative assessment of the content of essential oil in the samples of Origani vulgaris herba and Tanaceti vulgaris flores was carried out by the method of hydrodistillation. To determine the quantitative content of the sum of flavonoids in Hyperici herba, Artemisiae absinthii herba, Leonuri herba and the sum of flavonoids and phenolcarboxylic acids in Tanaceti vulgaris flores, a spectrophotometric method was used.Results and discussion. In the course of resource and phytochemical studies of representatives of the medicinal flora of the Middle Urals, a comprehensive assessment of the state of populations of wild medicinal plants – sources of medicinal plant raw materials (Origani vulgaris herba, Hyperici herba, Tanaceti vulgaris flores, Artemisiae absinthii herba and Leonuri herba) was carried out. The results are included in the electronic inventory of wild medicinal plants of the Middle Urals.Conclusion. The conducted complex of studies will allow updating information about the medicinal flora of the Middle Urals in order to use raw materials for the creation of medicines.

scholarly journals Investigation of Walnut Herbal Drug Raw Material

2019 ◽  
Vol 8 (4) ◽  
pp. 38-46
Author(s):  
N. V. Chebyshev ◽  
A. V. Strelyaeva ◽  
D. I. Lezhava ◽  
A. N. Luferov ◽  
N. V. Bobkova ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Juglans Regia ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Alcohol Extract ◽  
Plant Raw Materials ◽  
Active Substances

Introduction. Walnut (Juglans regia L.) is a medicinal plant containing a large number of biologically active substances. A number of authors propose to use walnut leaves as medicinal raw materials, in which juglone, flavonoids, tannins, ascorbic acid and other substances are identified. Currently, a standardization technique for this type of raw material has been developed and proposed. However, the medicinal plant walnut can be a source of other types of raw materials, such as milky-waxed walnuts, walnut bark, and walnut partitions. These types of medicinal raw materials contain a large number of biologically active substances and have a great potential for pharmacological activity. Therefore, the study with the subsequent standardization of medicinal plant material of walnut fruits in the stage of milk-wax ripeness and walnut bark is relevant.Aim. The aim of the study is to study the external signs, microscopy of raw walnut bark and walnut fruit in the stage of milky-wax ripeness and chemical composition of alcohol extract from these types of raw materials.Materials and methods. Chromato-mass spectrometry and TLC were used in the work.Results and discussion. When describing external signs and microscopy, diagnostic signs of both whole and crushed raw materials, and powder of walnut bark, and fruits of walnut in the stage of milky-wax ripeness were revealed. Alcohol extract obtained from medicinal plant raw materials walnut bark is a clear brown liquid. Alcohol extract obtained from medicinal plant raw materials of walnut fruit at the stage of milky-wax ripeness is a transparent, green-brown liquid with a fragrant odor.Conclusion. Gallic acid was identified by TLC in walnut bark. Chromato-mass spectrometry in alcohol extraction from the fruit of walnut in the stage of milky-wax maturity was able to identify 17 compounds belonging to different classes of biologically active substances. Sugars, flavonoids, coumarin phenolic compounds, organic acids were identified. In alcoholic extraction from the bark of a walnut, marker compounds have been determined, the combination of which makes it possible to quickly identify this type of raw material using chromatography-mass spectrometry. 

scholarly journals FLAVONOIDS FROM THE BUDS OF THE HORSE CHESTNUT (AESCULUS HIPPOCASTANUM L.)

2020 ◽  
pp. 123-129
Author(s):  
Vladimir Aleksandrovich Kurkin ◽  
Pavel Viktorovich Belov
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Uv Spectroscopy ◽  
Raw Material ◽  
Aesculus Hippocastanum ◽  
Horse Chestnut ◽  
Plant Raw Materials ◽  
Wide Range ◽  
New Type ◽  
First Time

The buds of horse chestnut (Aesculus hippocastanum L., Hippocastanaceae family) is a new promising species of medicinal plant raw material. The prospect of studying the buds of this plant is due to the content of flavonoids in them, which have a wide range of pharmacological effects. Flavonoids are interesting for their capillary-strengthening action, which allows them to be used in the treatment of chronic venous insufficiency. This fact is consistent with the practice of using drugs from other organs of horse chestnut (seeds, leaves) as venotonic and angioprotective drugs. In addition, flavonoids are also characterized by antioxidant, anti-inflammatory, antimicrobial and antifungal activity. The actuality of the study of horse chestnut buds as a new type of medicinal plant material is also supported by the need to develop of the new effective and safe drugs based on the raw materials of this plant. The aim of this study was to determine the flavonoid composition of the buds of Aesulus hippocastanum. In the course of the work from the buds of horse chestnut by the method of column chromatography on silica gel L 100/160 was for the first time there were isolated and characterized using 1H-NMR, 13C-NMR, UV spectroscopy and mass spectrometry the flavonoid compounds rhamnocitrin (7-O-methylkaempferol), and accompanying 7,4′-dimethylkaempferol. The dominant and diagnostic significant flavonoid for the horse chestnut buds is rhamnocitrin. The results indicate the prospects for further study of the buds of the horse chestnut as a new type of medicinal plant raw materials.

scholarly journals Pulsatilla alba: analytical review of spread, chemical composition, biological activity and medical application

2021 ◽  
pp. 10-14
Author(s):  
Anna Krvavych ◽  
Nataliia Reviakina ◽  
Lesia Zhurakhivska ◽  
Iryna Hubytska ◽  
Roksolana Konechna
Keyword(s):  
Chemical Composition ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Folk Medicine ◽  
Medical Application ◽  
Biologically Active ◽  
Raw Material ◽  
Sources Of Information ◽  
Scientific Publications ◽  
Plant Raw Materials

The object of analytical study is the medicinal plant Pulsatilla alba. This species is rare, the stocks of herbal raw materials are limited, and there are no Pulsatilla alba-based medicines on the Ukrainian market. The aim of study was to analyze and summarize data on the range, content of biologically active compounds and the spectrum of use in pharmacy and medicine Pulsatilla alba. Materials and methods. Literary and electronic sources of information on the distribution, chemical composition and pharmacological activity of Pulsatilla alba. Results. Pulsatilla alba is a plant of the Ranunculaceae family, characterized by a high content of biologically active organic compounds, namely organic acids, traces of alkaloids, vitamins, resinous and tannins, about 20 different macro-and micronutrients, essential oils, γ-lactones, triterpenoids, sterols, chelidonic acid, coumarins, as well as giving it protection status make it an interesting object for research. Analysis of scientific publications revealed that plants of the family Ranunculaceae, in particular, Pulsatilla alba contain a significant amount of biologically active substances, have numerous pharmacological activities, have long been used in folk medicine, and is a promising raw material for the production of phytopreparations. The volume of processing of medicinal plant raw materials in Ukraine in one year is from 5 to 6 thousand tons, the amount of raw materials for export reaches more than 3 thousand tons per year. About 1,000 tons of raw materials consumed in Ukraine are imported and 1,500 tons are domestically produced. Conclusions. Therefore, as populations of rare low-competitive species of the Ranunculaceae family are particularly endangered, displaced by tree, shrub and highly competitive trivial violent herbaceous species due to the widespread use of Pulsatilla alba in folk medicine as an antitumor, hypnotic, hypnotic, antifungal, antifungal research which should be continued

scholarly journals IDENTIFICATION OF PERMISSIBLE AREAS OF PREPARATION OF MEDICINAL VEGETABLE RAW MATERIALS NEAR TRANSPORT LINES

2020 ◽  
pp. 179-186
Author(s):  
Nina Alekseyevna Dyakova ◽  
Aleksey Ivanovich Slivkin ◽  
Yelena Yevgen'yevna Chupandina ◽  
Sergey Petrovich Gaponov
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Steppe Zone ◽  
Biologically Active ◽  
Raw Material ◽  
Traffic Load ◽  
Dust Particles ◽  
Forest Steppe ◽  
Plant Raw Materials ◽  
Vegetable Raw Materials

The purpose of the work is to study the permissible distance for the collection of medicinal plant raw materials near transport highways of different degrees of loading. The study was carried out in the Voronezh region on the example of eight different types of medicinal vegetable raw materials (Herring grass bitter, avian mountain grass, five-foot desert grass, plain thousand-year-old grass, double-ground nettle leaves, large planter leaves, common pajma flowers, core lip flowers) Collected in time of procurement along and at different distance from roads and railways of different degree of load in different natural zones, regulated by normative documentation. In the analyzed samples, the content of standardized biologically active substances, as well as heavy metals, pesticides, radionuclides, was previously estimated and full compliance with pharmacopoeia requirements was shown. In this work, the analysis was carried out on the level of ash insoluble in hydrochloric acid in the medicinal plant raw material, which makes it possible to estimate contamination of the raw material with dust particles. On the basis of the obtained data using the mathematical simulation method, the permissible distances from the transport lines, which can be recommended for the collection of safe medicinal plant raw materials, have been identified: Distance from major roads and highways loaded by road in forest natural zone conditions – at least 230 m, in forest steppe zone conditions – at least 300 m, in steppe zone conditions devoid of wood and shrub vegetation, – Not less than 660 m, near non-high-speed roads characterized by low traffic load – not less than 160 m, near railway lines – not less than 130 m. The obtained results can be recommended for safe collection of medicinal vegetable raw materials.

scholarly journals Pharmacognostic and pharmacological study of liquid extract of Crataegus Submollis Sarg. Flowers

2020 ◽  
Vol 19 (5-6) ◽  
pp. 160-164
Author(s):  
Ilnur Kh. Shaikhutdinov ◽  
Tatyana V. Morozova ◽  
Vladimir A. Kurkin ◽  
Elena N. Zaitceva ◽  
Olga E. Pravdivtseva ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Pharmacological Study ◽  
Antidepressant Activity ◽  
Raw Material ◽  
Intragastric Administration ◽  
Total Flavonoids ◽  
Cardiotonic Agents ◽  
Plant Raw Materials ◽  
Liquid Extract

The flowers and fruits of various species of the hawthorn genus (Crataegus L.) are widely used in domestic and foreign medical practice as cardiotonic agents. A perspective species for collecting of the raw material is Crataegus submollis Sarg. It was determined that 70% ethanol is an optimal extragent for the extraction of flavonoids from Crataegus submollis Sarg. flowers. The content of the total flavonoids in terms of hyperoside in the liquid extract of Crataegus submollis Sarg. flowers is 0,24 0,01%. It was established that liquid extract of Crataegus submollis Sarg. with using of 70% ethanol in case of a single intragastric administration in the dose of 100 l/kg shows significant antidepressant activity. Crataegus submollis Sarg. flowers are the perspective medicinal plant raw materials.

scholarly journals Powder from chickling vetch valves in the production of functional biscuits

2020 ◽  
Vol 222 ◽  
pp. 03008
Author(s):  
A.S. Jaboeva ◽  
Z.S. Dumanisheva ◽  
A.Ch. Toguzaeva ◽  
A.A. Shiritov ◽  
A.D. Thaitlov
Keyword(s):  
Quality Indicators ◽  
Functional Food ◽  
Food Production ◽  
Raw Materials ◽  
Raw Material ◽  
Plant Raw Materials ◽  
Physico Chemical ◽  
New Type ◽  
The Rich ◽  
Pectin Substances

Currently, it is necessary to search for non-traditional sources of plant raw materials characterized by a high content of indigestible polysaccharides having a beneficial effect on human body functions. One of the rich sources of high-molecular carbohydrates is the chickling vetch valves. The use of a new type of raw material in food production will expand the range of functional food products. The technology of powder from chickling vetch valves is developed, its organoleptic quality indicators are determined and the period of storage in warehouse premises is set. Based on the results of the study of the chemical composition of the powder, it was found that it is a valuable source of fiber, lignin, hemicellulose and pectin substances. It was found that when the powder is introduced into the recipe of biscuits in the amount of 1.1-2.2 % by weight of flour, the best organoleptic and physico-chemical quality indicators of finished products are achieved. It was found that when consuming 100 g of the developed products, the human body’s need for dietary fiber is met by 18.3-23.2 %.

scholarly journals Changes in analytical characteristics of pectic substances when freezing berries

2021 ◽  
Vol 285 ◽  
pp. 03016
Author(s):  
Irina Sobol ◽  
Ludmila Rodionova ◽  
Ludmila Donchenko ◽  
Albina Varyvoda
Keyword(s):  
Positive Impact ◽  
Raw Materials ◽  
The Body ◽  
Raw Material ◽  
Black Currant ◽  
Plant Raw Materials ◽  
Radioactive Nuclides ◽  
Complexing Ability ◽  
And Storage ◽  
Pectin Substances

Pectin substances are valuable components of plant cells. They have properties that allow them to be used in various industries - water retaining, gel-forming and complexing abilities. The most important property that has a positive impact on human health is the complexing ability. It is the property of pectin substances to bind heavy and toxic metals, radioactive nuclides, free radicals and other toxins in insoluble complexes and remove them from the human body. Due to their complexing ability pectin substances are used in medicines aimed at reducing cholesterol in the body, prolonging the effect of drugs, reducing the body’s allergic reactions to various substances. This property depends on the analytical characteristics of pectin substances and may vary depending on the type of raw material and the method of its processing. Currently, freezing is commonly used to preserve various types of fruits and berries, especially perishable ones. There are data in the literature about changes of pectin substances in various plant raw materials, but there are not enough data about changes of analytical characteristics of pectin substances during freezing and storage and their influence on the complexing ability. The article presents a study of the analytical characteristics of pectin substances contained in red and black currant berries during the process of their freezing and storage at low temperatures. Studies on their influence on the change in the complexing ability are presented.

scholarly journals AMINO ACID, FATTY ACID AND VITAMIN COMPOSITION OF ROSA CANINA L.

2021 ◽  
Vol 447 (3) ◽  
pp. 39-43
Author(s):  
Y.S. Ikhsanov ◽  
K.M. Kusainova ◽  
G.Y. Tasmagambetova ◽  
N.T. Andasova ◽  
Y.A. Litvinenko
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Biologically Active ◽  
Raw Material ◽  
The Arctic ◽  
Distribution Area ◽  
Rosa Canina ◽  
Plant Raw Materials ◽  
Soxhlet Apparatus ◽  
The Republic

The genus rose hips, or rose (Rosa L.), belongs to the Rosaceae family. It has many cultural forms, bred under the general name Rose. Now, more than 400 species of rose hips known. Usually these are erect shrubs, less often lianas, sometimes-low tree-like forms or almost herbaceous plants. Rosehip is common in the temperate and subtropical zones of the Northern Hemisphere, it can often found in the mountainous regions of the tropical belt. Some types of rose hips distributed from the Arctic Circle in the north to Ethiopia in the south. On the American continent - from Canada to Mexico. The most favorable conditions for Rosehip are in the Mediterranean region. Several species of the genus Rosehip have a wide distribution area. Kazakhstan possesses significant resources of medicinal plant raw materials. Among the most priority representatives of the wild flora are species of the wild rose genus - Rosa L. as the most valuable medicinal plant. In total, 21 species of wild rose grow in the republic, including 5 in Central Kazakhstan: R. glabrifolia - w. naked, R. laxa Retz. - w. loose, R. acicularis Lindl. - (w. Spiny), R. majalis Herrm. (R. cinnamomea L.) - w. May (w. cinnamon) and R. pimpinellifolia L. (R. spinosissima L.) - w. femoral. Kazakh species of the genus Rosa L Rosehip fruits distinguished by a high content of biologically active substances and are widely used in medicine. Plant raw materials collected in the southern region of the Republic of Kazakhstan (Almaty region). The crushed air-dry raw material was extracted with hexane and chloroform in a raw material-reagent ratio (1:10) in a Soxhlet apparatus. Plants of the genus Rosa are rich in vitamins A, C, E and group B, and also contain sugars, flavonoids, saponins, phytosterols, glycosides, tannins, organic acids, amygdalin, essential oils. Thus, rosehip is a promising raw material for the creation of domestic medicines. This article examines the study of the quantitative composition of amino acids and vitamins in the fruits of the species of the genus Rosa widespread in Kazakhstan in the supercritical extract, isolated and the fruits of the Rosa canina plant, in order to establish the possibility of using and with the subsequent cultivation of the selected species.

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