scholarly journals Photoacoustic lymphangiography before and after lymphaticovenular anastomosis

2021 ◽  
Vol 48 (3) ◽  
pp. 323-328
Author(s):  
Anna Oh ◽  
Hiroki Kajita ◽  
Eri Matoba ◽  
Keisuke Okabe ◽  
Hisashi Sakuma ◽  
...  

Background Lymphaticovenular anastomosis (LVA) is a minimally invasive surgical procedure used to treat lymphedema. Volumetric measurements and quality-of-life assessments are often performed to assess the effectiveness of LVA, but there is no method that provides information regarding postoperative morphological changes in lymphatic vessels and veins after LVA. Photoacoustic lymphangiography (PAL) is an optical imaging technique that visualizes the distribution of light-absorbing molecules, such as hemoglobin or indocyanine green (ICG), and provides three-dimensional images of superficial lymphatic vessels and the venous system simultaneously. In this study, we performed PAL in lymphedema patients before and after LVA and compared the images to evaluate the effect of LVA.Methods PAL was performed using the PAI-05 system in three patients (one man, two women) with lymphedema, including one primary case and two secondary cases, before LVA. ICG fluorescence lymphography was performed in all cases before PAL. Follow-up PAL was performed between 5 days and 5 months after LVA.Results PAL enabled the simultaneous visualization of clear lymphatic vessels that could not be accurately seen with ICG fluorescence lymphography and veins. We were also able to observe and analyze morphological changes such as the width and the number of lymphatic vessels and veins during the follow-up PAL after LVA.Conclusions By comparing preoperative and postoperative PAL images, it was possible to analyze the morphological changes in lymphatic vessels and veins that occurred after LVA. Our study suggests that PAL would be useful when assessing the effect of LVA surgery.


Author(s):  
Dheeraj Kumar Tyagi ◽  
Shivakumar .

Lifestyle disorders are one of the biggest threats for the population living unhealthy lifestyle. Sthoulya (Obesity) is one such disorder which creates lot of physical as well as mental disorder to the sufferer. Due to changing lifestyle, comforts and dietary habit lots of individuals changed their life totally. Obesity is a growing disease in developed and developing countries. Prevalence is drastically hike in past few years. Ayurveda, the science of life with which we can manage and control lots of lifestyle disorders. Focusing on dietary and lifestyle management along with treatment, we can overcome the hazards of obesity which is growing in a uncontrolled manner. The available data is based on the clinical findings only. Aim and objective: To assess the effect of “Guru Cha Atarpanam Chikitsa” in the management of Sthoulya. Setting: Swastharakshana evam Yoga, OPD and IPD, SDMCAH, Hassan. Method: Udwarthana, Parisheka, Shamana Aushadhis, Ahara, and Vihara was followed within the treatment duration and effect of treatment was assessed before and after treatment, advised for follow up. Results: The treatment adopted is effective in the management of Sthoulya and to improve the quality of life.



2014 ◽  
Vol 41 (1) ◽  
pp. 018-022 ◽  
Author(s):  
Wilson Cintra Júnior ◽  
Miguel Luiz Antonio Modolin ◽  
Rodrigo Itocazo Rocha ◽  
Thadeu Rangel Fernandes ◽  
Ariel Barreto Nogueira ◽  
...  

OBJECTIVE: to evaluate the importance of treatment of deformities caused by massive localized lymphedema (MLL) in the severely obese. METHODS: in a period of seven years, nine patients with morbid obesity and a mean age of 33 years underwent surgical resection of massive localized lymphedema with primary synthesis. This is a retrospective study on the surgical technique, complication rates and improved quality of life. RESULTS: all patients reported significant improvement after surgery, with greater range of motion, ambulation with ease and more effective hygiene. Histological analysis demonstrated the existence of a chronic inflammatory process marked by lymphomonocitary infiltrate and severe tissue edema. We observed foci of necrosis, formation of microabscesses, points of suppuration and local fibrosis organization, and pachydermia. The lymphatic vessels and some blood capillaries were increased, depicting a framework of linfangiectasias. CONCLUSION: surgical treatment of MLL proved to be important for improving patients' quality of life, functionally rehabilitating them and optimizing multidisciplinary follow-up of morbid obesity, with satisfactory surgical results and acceptable complication rates, demonstrating the importance of treatment and awareness about the disease.





2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Jia Wang ◽  
Zhiwei Li ◽  
Huankai Zhang ◽  
Ning Gao ◽  
Guoying Mu

Purpose. To analyze the keratectasia area (KEA) shown in corneal topography before and after corneal cross-linking (CXL) in patients with progressive keratoconus (KC) and figure out whether KEA is appropriate for evaluating the effect of CXL. Methods. A retrospective analysis was conducted in 34 eyes from 24 progressive KC patients who have underwent CXL from 2015 to 2017. Area with K-value more than 47D shown in the corneal topography was marked and identified as KEA. Keratometry (K1, K2, and Kmax), KEA, thinnest corneal thickness (TCT), and endothelial cell density (ECD) were evaluated preoperatively or at months 3, 6, and 12 postoperatively. The changes of KEA before and after operation were evaluated. The relation of KEA and other parameters, including Kmax and TCT, was analyzed. Results. Linear regression model revealed the KEA, Kmax, K1, and K2 decreased after CXL in model y = 0.9622 -0.02408 x (P<0.05), y = 0.9982 -0.003469 x(P<0.05), y = 0.9977 + -0.001347 x(P<0.05), y = 0.9992 + -0.001779 x(P<0.05) (y represents KEA, Kmax, K1, or K2; x represents time (month)). The KEA is significantly decreased in early stage (before month 3) (P<0.05); however, the Kmax, K1, and K2 have no significant decrease in early stage (P= 0.09, 0.19, 0.32). Conclusions. The KEA is more sensitive than K-value in describing the morphological changes of cornea after CXL, especially in early stage after treatment.



Pathogens ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 24 ◽  
Author(s):  
François Peyron ◽  
Coralie L’ollivier ◽  
Laurent Mandelbrot ◽  
Martine Wallon ◽  
Renaud Piarroux ◽  
...  

Women infected with toxoplasmosis during pregnancy do not present symptoms in most cases, but the consequences of the congenital infection may be severe for the unborn child. Fetal damage can range from asymptomatic to severe neurological alterations to retinal lesions prone to potential flare up and relapses lifelong. Despite the possible severity of outcome, congenital toxoplasmosis (CT) is a neglected disease. There is no consensus regarding screening during pregnancy, prenatal/postnatal treatment or short or medium term follow-up. Since 1992, France has offered systematic serological testing to non-immune pregnant women, monthly until delivery. Any maternal infection is thus detected; moreover, diagnosis of congenital infection can be made at birth and follow-up can be provided. “Guidelines” drawn up by a multidisciplinary group are presented here, concerning treatment, before and after birth. The recommendations are based on the regular analysis of the literature and the results of the working group. The evaluation of the recommendations takes into account the robustness of the recommendation and the quality of the evidence.



2011 ◽  
Vol 15 (4) ◽  
pp. 185-195 ◽  
Author(s):  
Ingrid Djukanovic ◽  
Lars Brudin ◽  
Margaretha Hagberg ◽  
Bo Tillander ◽  
Maria Cöster


Author(s):  
Shaya MacDonald ◽  
Susan Korol ◽  
Todd Vassallo ◽  
Cathy MacDougall

The current study evaluated the effectiveness of a novel three-hour Guided Mindfulness Program on participants’ management of depression, anxiety and stress. The intervention included an educational component emphasizing the psychological value of mindfulness practice combined with a practical training component in mindfulness techniques. The Depression Anxiety Stress Scale was administered at three points in time before and after participation in the program. Additionally, semi-structured interviews were conducted to explore perceived quality of life, happiness, and stress 4 to 8 weeks following the program. All participants reported improvements in overall well-being and reported significant decreases in negative affect when comparing pre-program scores (baseline) to follow-up scores. Notably, qualitative interview results indicated that participants attributed most positive post-program results to informal mindfulness practice.



Author(s):  
Zhongjie Long ◽  
◽  
Kouki Nagamune ◽  
◽  

Arthroscopic surgery is a minimally invasive surgical procedure that is widely used on joints. However, conventional endoscope-based arthroscopic surgery does not provide stereoscopic information to the surgeon. To overcome this limitation, we have developed a modified endoscopic system that uses an optical fiber (1 mm diameter) for three-dimensional imaging of knee joints. Our endoscopic system is able to operate underwater in real time. It consists of a laser beam that is projected on the surface of the object to be imaged via an optical fiber. A prism is used to decrease the length and diameter of baseline and endoscope tube, respectively. The small diameter (8 mm) of our endoscope makes it extremely convenient for application in arthroscopic surgery. The feasibility of the proposed system has been demonstrated via experiments on synthetic knee joints.



2015 ◽  
Vol 22 (6) ◽  
pp. 1205-1211 ◽  
Author(s):  
Daniel J Vreeman ◽  
John Hook ◽  
Brian E Dixon

Abstract Objective To describe the perspectives of Regenstrief LOINC Mapping Assistant (RELMA) users before and after the deployment of Community Mapping features, characterize the usage of these new features, and analyze the quality of mappings submitted to the community mapping repository. Methods We evaluated Logical Observation Identifiers Names and Codes (LOINC) community members’ perceptions about new “wisdom of the crowd” information and how they used the new RELMA features. We conducted a pre-launch survey to capture users’ perceptions of the proposed functionality of these new features; monitored how the new features and data available via those features were accessed; conducted a follow-up survey about the use of RELMA with the Community Mapping features; and analyzed community mappings using automated methods to detect potential errors. Results Despite general satisfaction with RELMA, nearly 80% of 155 respondents to our pre-launch survey indicated that having information on how often other users had mapped to a particular LOINC term would be helpful. During the study period, 200 participants logged into the RELMA Community Mapping features an average of 610 times per month and viewed the mapping detail pages a total of 6686 times. Fifty respondents (25%) completed our post-launch survey, and those who accessed the Community Mapping features unanimously indicated that they were useful. Overall, 95.3% of the submitted mappings passed our automated validation checks. Conclusion When information about other institutions’ mappings was made available, study participants who accessed it agreed that it was useful and informed their mapping choices. Our findings suggest that a crowd-sourced repository of mappings is valuable to users who are mapping local terms to LOINC terms.



Sign in / Sign up

Export Citation Format

Share Document