scholarly journals Plantar Fasciitis—A Comparison of Treatment with Intralesional Steroids versus Platelet-Rich Plasma

2017 ◽  
Vol 107 (6) ◽  
pp. 490-496 ◽  
Author(s):  
Carlos Acosta-Olivo ◽  
Jorge Elizondo-Rodriguez ◽  
Ricardo Lopez-Cavazos ◽  
Felix Vilchez-Cavazos ◽  
Mario Simental-Mendia ◽  
...  

Background: Many treatment options for plantar fasciitis currently exist, some with great success in pain relief. The objective of our study was to compare the use of intralesional steroids with platelet-rich plasma (PRP), using pain scales and functional evaluation, in patients with plantar fasciitis who did not respond to conservative treatment. Methods: A controlled, randomized, blinded clinical assay was performed. Patients were assigned to one of the two groups by selecting a sealed envelope. The steroid treatment group received 8 mg of dexamethasone plus 2 mL of lidocaine as a local anesthetic. The PRP treatment group received 3 mL of PRP activated with 0.45 mL of 10% calcium gluconate. All of the patients were evaluated at the beginning of the study, and at 2, 4, 8, 12, and 16 weeks post-treatment with the Visual Analog Scale (VAS), Foot and Ankle Disability Index (FADI), and American Orthopedic Foot and Ankle Society (AOFAS) scale. Results: The right foot was the most frequently affected foot (63%). The average age of the patients was 44.8 years (range, 24–61 years). All scales used (VAS, FADI and AOFAS) showed that the difference was not statistically significant between the two groups. Conclusions: We can conclude that the use of PRP is an effective treatment method for patients with plantar fasciitis who do not respond to conservative treatment because PRP demonstrates an efficacy equal to that of steroids. However, the cost and the time for preparation the PRP are two of the disadvantages of this treatment.

Author(s):  
Umit Yalcin

Background: Plantar fasciitis (PF) is one of the most common foot problems in adults. Conservative treatments are proportionally 90-95% successful. In this study, author aimed to compare the effectiveness of ozone therapy (OT) treatment of platelet rich plasma (PRP) injections in PF patients.Methods: In the study, which was made prospectively, patients were randomly divided into two groups. In the first group (n=20), patients were injected with PRP in 3 sessions at a one week intervals, and in the second group (n=22) OT was injected in the same way. Each patient was evaluated with visual pain score before as well as 1 month after treatment in terms of pain, whereas the foot function index (FFI) was evaluated with the score in terms of functionality.Results: In both groups, the 1st month VAS score and FFI score showed significant decrease (p<0.05) after treatment compared to before treatment. The decrease in VAS score and FFI score after treatment in the PRP group was significantly higher than the OT group (p˂0.05).Conclusions: As a result of this study, authors found that both PRP and OT were beneficial in terms of pain and functional level in the treatment of PF, but in patients who underwent PRP, authors found that there was more statistical improvement in terms of both parameters than patients who received OT. In light of the absence of a previous publication comparing these two treatment options in PF treatment, this study contributes to the literature.


2021 ◽  
pp. 6-8
Author(s):  
Abdul Hassan Khan ◽  
Prasanta Kumar Pujari ◽  
Bikramjit Gayen ◽  
Dipak Kumar Jha ◽  
Debarshi Jana

Background: Osteoarthritis (OA) knee is one of the most prevalent musculoskeletal disorders in elderly population. It has got various treatment options but most are unsatisfactory. In recent years Platelet-rich plasma (PRP) is emerged as a promising treatment modality and classied as “Orthobiologics”. PRPenhances tissue recovery, by catalysing the body's natural healing response and tissue repair process. Aim And Objectives:Tocompare the efcacies oftreatmentwithPRPinjectionandconservative treatmentwithNSAIDSandexercise inOAknee. Materials And Methods:This was a observational study in which comparisons of different outcomes were made on the efcacies of the treatments with PRPinjection and compared to conservative treatment with NSAIDS and exercise in OAknee. The study was conducted in the Department of Orthopedics in Ramkrishna Mission SevaPratisthan. Atotal number of 60 patients with power 80% were randomly selected from the patients with OA attended OPD during the period from June 2019 to June 2021. The patients were divided into two groups of 30 patients in each group. The patients of the one group were treated with intra-articular PRPinjection and the patients of another group were treated conservatively with NSAIDS and exercise. After the completion of treatment, the patients were followed-up for 1 year and the outcomes of the treatments were assessed by WOMAC (The Western Ontario and McMaster Universities Osteoarthritis Index) knee assessment scoring system. Results:At 1 year the completion of treatments it was found that both clinical and functional improvements of the patients were signicantly better than the initiation of treatments (p<0.0001). However, the improvements of the patients treated with PRPinjection were signicantly better than the patients treated conservatively with NSAIDS and exercise (p<0.001). Conclusion: From the results of the study it may be concluded that PRP injection is better than conservative treatment with NSAIDS and exercise to treat OAknee


2014 ◽  
Vol 3 (1) ◽  
pp. 14-18
Author(s):  
Timuçin Baykul ◽  
Müge Çina Aksoy ◽  
Gülperi Koçer ◽  
Gülsün Yildirim ◽  
Doğan Dolanmaz

ABSTRACT Objectives Developmental odontogenic jaw cysts are generally connected with impacted or unerupted teeth. The conservative treatment options of these types of cysts will be presented. Study design In this study 17 cases operated in Süleyman Demirel and Selcuk Universities Faculty of Dentistry were included. The data of the cases were documented with respect to age, sex, localization, symptoms, presence of unerupted teeth on panoramic radiographs. The cysts were treated with marsupialization with an obturator made of acrylic resin in nine patients and a tube drain in eight patients to keep the window open. Results and conclusion Marsupialization was evaluated as extremely effective in 15 patients, the cysts completely disappeared and the permanent teeth were erupted, in two patients the cysts disappeared but the teeth were not erupted. Enucleation, marsupialization or their combination are the conventional treatment options of the jaw cysts. Large cysts may localize nearby the important anatomical structures or may involve unerupted permanent teeth. These kind of cysts may be treated with marsupialization in order to protect these anatomical structures or to allow the eruption of the permanent teeth. Marsupialization should be considered as an effective conservative treatment method of the jaw cysts during mixed dentition in the childhood. How to cite this article Aksoy MÇ, Koçer G, Yildirim G, Baykul T, Dolanmaz D. Conservative Treatment of Dentigerous Cysts in Childhood. Int J Experiment Dent Sci 2014;3(1):14-18.


2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 185-185
Author(s):  
Ryosuke Umino ◽  
Yu Ohkura ◽  
Masaki Ueno ◽  
Harushi Udagawa

Abstract Background Management of postoperative chylothorax generally involves nutritional regimens as well as pharmacological and surgical therapies, but a clear consensus has yet to be reached. The aim of this study was to clarify the usefulness of an etilefrine regimen to broaden the medical treatment options for postoperative chylothorax after esophagectomy with resection of the thoracic duct. Methods A total of 371 consecutive patients with esophageal cancer were identified from a prospectively constructed database at the Department of Gastroenterological Surgery, Toranomon Hospital between January 2011 and February 2017. They were patients with squamous cell carcinoma or adenocarcinoma of the esophagus including Siewert type I, II tumor of the esophagogastric junction who underwent subtotal esophagectomy. Of these 371 patients, 19 patients who were diagnosed with chylothorax as a postoperative complication were enrolled in this study. Results Conservative treatment achieved cure in 16 patients among 19 patients. The duration of chylothorax tended to be longer in the no-etilefrine group (n = 5) than in the etilefrine group (n = 11) (27.8 vs. 11.6 days; P = 0.078). The 14 patients among 19 patients was resected the thoracic duct. Etilefrine was used in 12 of these 14 patients. Among these 12 patients, 3 required surgical treatment and the remaining 9 patients were cured with conservative treatment. The duration of chylothorax was shorter in the conservative treatment group than in the surgical treatment group (11.9 vs. 36.3 days; P = 0.052). And also, with the use of etilefrine as adjuvant therapy, cure was achieved in 9 patients (75%) without surgical intervention. Conclusion The findings of this study suggest the effectiveness of etilefrine in patients with chylothorax following esophagectomy. The drug was effective even in post-TDR chylothorax, an often intractable condition that is difficult to treat conservatively. However, when the effectiveness of etilefrine regimen is unexpectedly poor, it is important to switch from drug therapy to surgical treatment in the early stage of this complication. Disclosure All authors have declared no conflicts of interest.


2020 ◽  
pp. 036354652093729
Author(s):  
Erik Hohmann ◽  
Kevin Tetsworth ◽  
Vaida Glatt

Background: Plantar fasciitis is a common cause of heel pain. Corticosteroid injections are commonly used and proven to be effective, and lately platelet-rich plasma (PRP) has been used with mixed results. Purpose: To perform a systematic review and meta-analysis comparing intralesional injections of PRP and steroid infiltration. Study Design: Systematic review and meta-analysis. Methods: A systematic review of Medline, Embase, Scopus, and Google Scholar including all level 1 and 2 studies from 2010 to 2019 was perfomed. American Orthopaedic Foot and Ankle Society and visual analog scale for pain scores were used as outcome variables. Publication bias and risk of bias was assessed with the Cochrane Collaboration tools. The Grading of Recommendations, Assessment, Development and Evaluations system was used to assess the quality of the body of evidence. Heterogeneity was assessed with χ2 and I2 statistics. Results: Fifteen studies were included in the analysis. Nine studies had a high risk of bias. There was 1 study with high quality, 9 with moderate, 2 studies with low, and 3 with very low quality. The pooled estimate for the American Orthopaedic Foot and Ankle Society score demonstrated nonsignificant differences at 1 month ( P = .4) and 3 months ( P = .076). At 6 months ( P = .009) and 12 months ( P = .009), it indicated significant differences in favor of PRP. The pooled estimate for visual analog scale demonstrated nonsignificant differences at 1 month ( P = .653). At 3 months ( P = .0001), 6 months ( P = .002), and 12 months ( P = .019), it yielded significant differences in favor of PRP. Conclusion: The results of this systematic review and meta-analysis suggest that PRP is superior to corticosteroid injections for pain control at 3 months and lasts up to 1 year. In the short term, there is no advantage of corticosteroid infiltration. However, the low study quality, high risk of bias, and different protocols for PRP preparation reduce the internal and external validity of these findings, and these results must be viewed with caution.


2021 ◽  
Vol 10 (19) ◽  
pp. 4561
Author(s):  
Sergio Tejero ◽  
Estefanía Prada-Chamorro ◽  
David González-Martín ◽  
Antonio García-Guirao ◽  
Ahmed Galhoum ◽  
...  

Despite the disabling nature of ankle osteoarthritis (OA), there is poor scientific evidence for a conservative treatment compared to the hip and knee OA. In this regard, most of the treatment options in use are not based on clinical studies of the ankle, and they are extracted from evidence obtained from clinical studies of other lower limb joints. However, this does not seem to be a good idea, since the aetiology of ankle OA is quite different from that of the hip or knee. Nonpharmacological and pharmacological treatments such as nonsteroidal anti-inflammatory drugs, hyaluronic acid, corticosteroid, platelet-rich plasma injection and mesenchymal stem cells injections have been reported. However, further research is required in this field to obtain a specific clinical practice guideline for the conservative treatment of ankle OA.


1996 ◽  
Vol 5 (4) ◽  
pp. 305-320 ◽  
Author(s):  
Bradley K. Kaya

Plantar fasciitis is a common sports injury that typically presents as heel pain. The purpose of this paper is to review the literature on plantar fasciitis, with emphasis on etiologic factors and current conservative management. A combination of anatomical and biomechanicai factors, repetitive forces, and training errors can predispose an athlete to plantar fasciitis. Most people with plantar fasciitis improve with conservative treatment. Treatment should initially be aimed at decreasing pain and inflammation through rest, modification of activity, medication, orthotics, and physical therapy. Identification of predisposing factors for each athlete is necessary to effectively treat the athlete and return him or her to sports activity. Although many treatment options are suggested in the literature, few have been studied for use with plantar fasciitis. Further research is needed to determine the effectiveness of conservative methods to manage plantar fasciitis.


2006 ◽  
Vol 53 (2) ◽  
pp. 71-79 ◽  
Author(s):  
Johann Pfeifer

Patients with intractable chronic constipation should be evaluated with physiologic tests after structural disorders and extracolonic causes have been excluded. Conservative treatment options should be tried excessively. If surgery is indicated subtotal colectomy with IRA is the treatment method of choice. However, segmental resection may be a good option for isolated megasigmoid, sigmoidocele or recurrent sigmoid volvulus. In general patients with GID should not be offered any surgical options because of their anticipated poor results. Moreover, patients with psychiatric disorders should be actively discouraged from resection as they tend to have poorer prognosis. Patients must be counseled that preoperative pain and/or bloating will likely persist even if surgery normalizes bowel frequency. Patients with associated problems may be better served by having a stoma without resection as both a therapeutic maneuver and a diagnostic trial. Colectomy is no option to treat pain and/or abdominal bloating.


GYNECOLOGY ◽  
2019 ◽  
Vol 21 (4) ◽  
pp. 24-26
Author(s):  
Gennady Y Yarin ◽  
Inna A Vilgelmi ◽  
Evgeny V Liuft

Background. Pelvic organ prolapse is one of the most common women's diseases worldwide. Genital prolapse incidence among women over 50 is on average 41%. There are variety methods for genital prolapse treatment; they are divided into surgical and non-surgical ones. One of the conservative treatment methods is a use of pessaries. According to different studies an efficacy of pessary therapy is approximately 60%. Aim to estimate a safety and efficacy of genital prolapse conservative treatment with a cube pessary on the basis on standardized questionnaires. Outcomes and methods. In ANO “NRITO Clinic” Urology and Gynecology Center 26 women with various degree genital prolapse were treated with pessary within the period from August 2015 to March 2016. Efficacy of pessaries use, patient satisfaction with this treatment method and complications rate were estimated. Results. Urogynecological cube pessary use in a treatment of various types of genital prolapse is quite an effective method (p


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