scholarly journals The Prospect of Serum Magnesium and an Electrolyte Panel as an Adjuvant Cardiac Biomarker in the Management of Acute Myocardial Infarction

2013 ◽  
Author(s):  
Ramesh Ramasamy
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Serum Magnesium ◽  
Cardiac Biomarker

scholarly journals Correlations of Serum Magnesium and Potassium in Acute Myocardial Infarction, Chronic Ischemic Heart Disease and Normal Healthy Volunteers of Bangladesh

2013 ◽  
Vol 3 (2) ◽  
pp. 50-56
Author(s):  
MBK Choudhury ◽  
MM Hossain ◽  
M Akhtaruzzaman ◽  
MM Jamal Uddin ◽  
MS Rahman ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Healthy Volunteers ◽  
Serum Magnesium ◽  
Ischemic Heart ◽  
Diagnostic Tools ◽  
Strong Positive Correlation ◽  
Chronic Ischemic Heart Disease

Magnesium (Mg) and potassium (K) are the major intracellular cations whose presence in the serum are low, but minor changes of those may show a remarkable change in the various body functions specially in the heart. The study was designed to find out the correlation between serum Mg and K in acute myocardial infarction (AMI), chronic ischemic heart disease (CIHD) and normal healthy volunteers. It was carried out over a period of 18 months in the Department of Biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU) in collaboration with Department of Cardiology, Sir Salimullah Medical College & Mitford Hospital (SSMC & MH) and Atomic Energy Center, Dhaka. A total of 101 subjects were included in which 32 subjects were AMI, 34 CIHD and 35 normal healthy volunteers. Serum glucose and serum creatinine were estimated to exclude diabetes and renal dystrophies. Estimation of serum CK-MB and ECG tracing were done as diagnostic tools of AMI and to categories the subjects into various groups. Serum Mg was estimated by Atomic absorption spectrophotometer and serum K by Ion sensitive electrode. The present study shows that there is a strong positive correlation of serum Mg and K in AMI, CIHD and healthy control subjects (r = 0.566, p<0.01 level). So it is suggested to estimate and supplement both Mg and K in IHD patients for their better management. DOI: http://dx.doi.org/10.3329/bjmb.v3i2.13812 Bangladesh J Med Biochem 2010; 3(2): 50-56

scholarly journals A fluorescent biosensor for cardiac biomarker myoglobin detection based on carbon dots and deoxyribonuclease I-aided target recycling signal amplification

RSC Advances ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 4463-4468 ◽  
Author(s):  
Jishun Chen ◽  
Fengying Ran ◽  
Qinhua Chen ◽  
Dan Luo ◽  
Weidong Ma ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Carbon Dots ◽  
Signal Amplification ◽  
Cardiac Biomarker ◽  
Target Recycling ◽  
Fluorescent Biosensor ◽  
Deoxyribonuclease I

A sensitive biosensor has been developed to detect myoglobin (MB), which is an important cardiac biomarker and plays a major role in the diagnosis of acute myocardial infarction (AMI).

scholarly journals Trends in Cardiac Biomarker Testing in China for Patients with Acute Myocardial Infarction, 2001 to 2011: China PEACE-Retrospective AMI Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0122237 ◽  
Author(s):  
Lijuan Zhan ◽  
Frederick A. Masoudi ◽  
Xi Li ◽  
Shuang Hu ◽  
Arjun K. Venkatesh ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiac Biomarker ◽  
Biomarker Testing

scholarly journals Evaluation of the Efficiency of N-terminal Pro-B-type Natriuretic Peptide for Diagnosis of Acute Myocardial Infarction

2020 ◽  
Author(s):  
Abuagla M. Dafalla ◽  
Leena A. Dafalla ◽  
ShamsEldein M. Ahmed ◽  
Yousif A. Mohammed ◽  
Adam D. Abakar ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Natriuretic Peptide ◽  
Predictive Value ◽  
Troponin I ◽  
Venous Blood ◽  
Cardiac Biomarkers ◽  
Control Group ◽  
Heart Cell ◽  
Cardiac Biomarker

Background: Cardiac diseases are one of the major causes of death worldwide with increasing incidence rate per year, particularly in developing countries such as Sudan owing to urbanization and changing lifestyle. Myocardial infarction is a consequence of the imbalance between the heart blood supply and the required heart cell; this disorder leads to necrosis of myocardium and may cause death. It could be diagnosed by at least two of the following criteria: chest pain, electrocardiography (ECG) elevation, and levels on cardiac biomarkers. This study aimed to evaluate the efficiency of N-terminal pro-B-type natriuretic peptide (NTproBNP) for the diagnosis of acute myocardial infarction (AMI).  Methods: This analytical case–control hospital-based study was conducted on a total of 70 individuals, of which 40 participants were suspected of or diagnosed with AMI, while 30 healthy subjects  were included as a control group. Three ml of venous blood were collected in lithium heparin containers. Troponin I (TnI) as a cardiac biomarker was measured by TOSOH AIA-360, while the NTproBNP level was detected using I-Chroma II. Personal and clinical data were collected directly from each participant using a predesigned questionnaire. Results: A significant increase in the TnI level (mean: 13.13 ± 18.9 ng/ml) and NTproBNP (mean: 5756.5 ± 8378.2 pg/mL) in AMI patients were detected when compared with control mean (0.02 ± 0.00 ng/ml and 57.8 ± 42.32 pg/mL, respectively). Conclusions: NTproBNP gave a high sensitivity (87.5%), specificity (100%), positive predictive value (100%), and negative predictive value (85.7%) in the diagnosis of AMI when compared with another cardiac biomarker such as TnI. Keywords: acute myocardial infarction, NTproBNP, troponin I, Medani Heart Center, Sudan

scholarly journals Comparison of Serum Magnesium and Potassium in Acute Myocardial Infarction and Chronic Ischemic Heart Disease

2012 ◽  
Vol 17 (1) ◽  
pp. 33-36
Author(s):  
MBK Choudhury ◽  
MS Rahman ◽  
MM Hassan ◽  
R Begum ◽  
N Hoque ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Serum Magnesium ◽  
Serum Glucose ◽  
Ischemic Heart ◽  
Cardiac Complications ◽  
Chronic Ischemic Heart Disease ◽  
Group I

The comparative study has been designed to estimate serum magnesium (Mg) and potassium (K) in patients with acute myocardial infarction (AMI) and chronic ischemic heart disease (CIHD). A total 61 subjects were selected and were divided as group-I (30 subjects of AMI) and group-II (31 subjects of CIHD). Laboratory investigations were done for estimation of serum glucose and serum creatinine to exclude the diabetes mellitus and renal disease. Serum Mg was estimated by atomic absorption spectrophotometer and serum K by ion selective electrode. This study showed that Mg and K level in serum is significantly lower in patients with AMI than that of CIHD subjects. Findings of the study suggested that significantly reduced serum level of Mg and K persists in AMI than those of CIHD, which may be the cause of further cardiac complications. So it may be recommended for estimation and supplementation of Mg and K in both the cases of AMI and CIHD patients for better management. DOI: http://dx.doi.org/10.3329/jdnmch.v17i1.12190 J. Dhaka National Med. Coll. Hos. 2011; 17 (01): 33-36

scholarly journals ACUTE MYOCARDIAL INFARCTION;

2018 ◽  
Vol 21 (02) ◽  
pp. 258-263
Author(s):  
Mukhtiar Hussain Jaffery ◽  
Khalida Shaikh ◽  
Ghulam Hussain Baloch ◽  
Syed Zulfiquar Ali Shah
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Serum Magnesium ◽  
Diabetic Patients ◽  
Inferior Wall ◽  
Female Population ◽  
Male And Female ◽  
Case Series Study ◽  
Acute Mi ◽  
The Mean

Objective: This descriptive case series study evaluates the frequency ofhypomagnesemia in patients with acute myocardial infarction. Patients and methods: Thismultidisciplinary conducted at Liaquat University Hospital Hyderabad and a private hospitalHyderabad from May 2010 to October 2010. All patients diagnosed as acute myocardialinfarction were further evaluated for type of myocardial infarction and serum magnesium level.Results: Out of 100 diabetic patients, 77 were males and 23 patients were females. The meanage and standard deviation of patients of male and female was 54.78 ± 8.82 (SD) and 53.64 ±10.82 (SD), respectively. The mean ± SD for serum magnesium in overall subjects was 1.24±0.48. Regarding the type of AMI inferior wall in 22 (29%), lateral wall in 17 (22%), anteroseptal in12 (16%), anterolateral -V1 in 07(09%), right ventricular in 10 (13%) and posterior wall in 07 (09%).The mean duration of acute MI in male and female population was 8.71±6.73 hours and17.70±14.57 hours (p<0.01) where as the mean duration of acute MI in hypomagnesemic andnormomagnesemic patient was 5.16±2.49 hours and 26.60±8.27 (p = 0.02) respectively. Themean serum magnesium level in male as well as female population was 1.32 ±0.21 mg/dl and1.46± 0.53 mg/dl p = 0.05, respectively. Regarding the hypomagnesemia in male and femalepopulation was 34(75.6%) and 16(53.3%) p=0.04, respectively. The hypomagnesemia was morepredominant in inferior 18(36.0%) and lateral 16 (32.0%) wall MI. Conclusions: Thehypomagnesemia was observed in patients with acute myocardial infarction with statisticalsignificance

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