scholarly journals Role of Squash Cytology in Intraoperative Diagnosis of Meningioma

2021 ◽  
Author(s):  
Gowri Prakasam ◽  
K Karkuzhali ◽  
Veeraraghavan Gurusamy
Keyword(s):  
Tamil Nadu ◽  
Frozen Section ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Histopathological Diagnosis ◽  
Suspected Case ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Cost Effective Technique

Introduction: Primary Central Nervous System (CNS) tumours constitute less than 2% of overall cancers in adults and are the second most frequently encountered tumours in children. Meningiomas form 24-30% of primary intracranial tumours. Most intrinsic brain tumours are soft and gelatinous in consistency, smear preparation can readily made which gives excellent cytological details when compared to frozen section as the latter produces ice crystal artifacts. Aim: To assess the diagnostic utility of squash cytological evaluation of meningiomas and its comparison with final histopathological diagnosis. Materials and Methods: The cross-sectional study was done at Thanjavur Medical College, Thanjavur, Tamil Nadu, India for period of three years from January 2015 to December 2017. Total of 54 clinically diagnosed and radiologically suspected case of meningiomas were selected. Smears were prepared from the biopsy samples sent in normal saline and stained by Haematoxylin and Eosin (H&E) method. The cytological features were noted and matched with biopsy findings. Descriptive statistics were used to analyse the results. Results: Total of 54 squash smears with male to female ratio was 1:1.5. Maximum number of cases were seen between 41- 50 years followed by 51-60 years. Complete concordance was obtained in 51 cases (94.44%) and partial concordance was noted in a case due to underestimation of malignancy grade in squash cytology. Out of 54 cases, two cases were found to be discordant with final histopathological diagnosis. Conclusion: Intraoperative squash cytology is easy, rapid, reliable and cost-effective technique for neurosurgical consultation with fairly high accuracy in diagnosing meningiomas.

scholarly journals Evaluation of female pelvic mass - correlation of clinical and histopathological findings in female patients attending at Birat Medical College and Teaching Hospital, Morang, Nepal

2020 ◽  
Vol 4 (3) ◽  
pp. 845-849
Author(s):  
Seema Kumari Mishra ◽  
Roshan Pradhan ◽  
Hanoon P Pokharel
Keyword(s):  
Clinical Diagnosis ◽  
Teaching Hospital ◽  
Pelvic Mass ◽  
Exploratory Laparotomy ◽  
Cross Sectional Study ◽  
Histopathological Diagnosis ◽  
Female Pelvis ◽  
Cross Sectional ◽  
Medical College ◽  
Pelvic Masses

Introduction: The female pelvis is a quite complex anatomical region consisting of uro-genital system as its main part and other structures like blood vessels, gastrointestinal tracts, lymphatics, nerves and a part of musculoskeletal system. Thus, the differential diagnosis of pelvic masses may be of gynecological or non gynecological origin. Gynecological pelvic masses are uterine, ovarian or adnexal masses which may be benign or malignant. Objective: The objective of this study was to evaluate the type of various gynecological pelvic masses and to correlate the preoperative diagnosis with histopathological diagnosis. Methodology: This was a hospital based cross sectional study conducted on 107 patients from September 2018 to September 2019 at Birat Medical College and Teaching Hospital (BMCTH) with presenting complian of lump in the abdomen. These patients underwent clinical examination, routine and specific investigations along with ultrasonographic evaluation and tumour markers to reach a preoperative clinical diagnosis. Patients were admitted and preanesthetic consultation was done. Patients were taken for therapeutic or diagnostic laparoscopy or exploratory laparotomy and diagnosis were confirmed with histopathological diagnosis. Results: Total 107 patients were enrolled in the study with age ranging from 21 to ≥70 years and among them majority (42.1%) were in the age group of 41-50 years. The most common presenting complain of patients were lower abdominopelvic pain (58.87%). The most common clinical diagnosis was leiomyoma in 39.25% patients followed by adenomyosis in 24.29% patients. The most common histopathological diagnosis was fibroid uterus seen in 42.05% patients. There were 2 (1.86%) patients of ovarian malignancies and 1 (0.93%) patient of uterine malignancy.

scholarly journals Prevalence of Anti-Red Cell Antibodies in Repeatedly Transfused Patients

2019 ◽  
Vol 14 (1) ◽  
pp. 73-77
Author(s):  
Masuma Ahmed Salsabil ◽  
Ashesh Kumar Chowdhury ◽  
Debashish Saha ◽  
Arif Ahmed Khan ◽  
Sazia Sultana
Keyword(s):  
Haemolytic Anaemia ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Red Cell ◽  
Cross Sectional ◽  
Transfusion Therapy ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio ◽  
Immune Haemolytic Anaemia

Introduction: The development of anti-RBC antibodies (alloantibodies and/or autoantibodies) can significantly complicate transfusion therapy, particularly in patients needed repeated transfusion. Objectives: To find out the prevalence of alloantibodies and autoantibodies in repeatedly transfused patients so that serious hazards due to immune reaction may be avoided. Materials and Methods: This descriptive cross-sectional study was carried out in Department of Immunology, BIRDEM and Armed Forces Institute of Pathology (AFIP) during the period of July 2015 to June 2016. Total 370 patients who had received at least five units of transfusions were enrolled in this study but known patients of auto immune haemolytic anaemia, patients in whom antibody was previously detected and pregnant women were excluded from the study. Blood grouping and Direct Anti-globulin Test (DAT) were performed with cell suspension using a poly-specific Coombs reagent. In cases of a positive DAT, further investigation using specific monoclonal reagents to detect IgG or a complement (C3d) was carried out. Serum was used to detect red cell alloantibodies using standard blood bank methods. Antibody identification was performed in antibody screening positive samples using red cell Identicells. Results: Maximum 132 (35.7%) patients were in the age group 1-10 years. The male-female ratio was 1.2:1. Among 370 total patients 290 were HHA and 80 were non-HHA. Antibody was detected in only 17(4.59%) patients. Among the Hereditary Haemolytic Anaemia (HHA) patients it was 11 (3.79%) but among the non-HHA patients it was 6(7.5%). Out of 8 auto-antibodies, 5 were anti IgG followed by 3 were anti C3d. Out of 14 alloantibodies, 4(28.6%) were anti E, 3(21.4%) were anti K and in 3(21.4%) cases specificity of alloantibody was not detected. Conclusion: Prevalence of anti-RBC antibodies was not so uncommon in multiple transfused patients. Journal of Armed Forces Medical College Bangladesh Vol.14(1) 2018: 73-77

scholarly journals Clinical Profile of Meningitis in Children

2018 ◽  
Vol 28 (1) ◽  
pp. 6-11
Author(s):  
MB Uddin ◽  
M Rahman ◽  
KI Jahan ◽  
S Yeasmin ◽  
F Rahman
Keyword(s):  
Aseptic Meningitis ◽  
Clinical Problem ◽  
Cross Sectional Study ◽  
Suspected Case ◽  
Pyogenic Meningitis ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Meningitis In Children ◽  
Untreated Individuals

Meningitis is an emergency clinical problem in pediatrics. The mortality from meningitis is close to 100% in untreated individuals and can still be up to 40% in children who received appropriate antibiotic therapy in developing countries. A cross sectional study was done to address the common presentation of meningitis among the children. The study was conducted in the Pediatric unit of Rajshahi Medical College Hospital from March 2008 to July 2009. A total of 130 suspected case of meningitis patients were included in the study. Among them 102 were diagnosed as meningitis of 66 children with pyogenic meningitis, 36 children with aseptic meningitis and 28 children without meningitis were taken as non meningitis group. This study showed that all patients (100%) had fever. 97 (95.10%) had symptom of convulsion. Vomiting was present in 62 (60.78%), excessive cry or irritability present in 50(49%) cases. This study expressed that 75 (73.53%) patients had bulged fontanel. Neck rigidity was present in 67 (65.69%). Only 32.35% had kernig’s sign positive and 17.65% present with Brudginsky’s sign positive. The infancy was the most vulnerable age for pyogenic meningitis. H. influenzae were the leading pathogen (24.24%) in infancy followed by S. pneumoniae (21.21%). The result shows that among 66 pyogenic meningitis, 26 (39.39%) were completely cured and 24 (36.37%) were cured with sequelae. Out of 36 aseptic meningitis 27 (75.00%) were completely cure.TAJ 2015; 28(1): 6-11

scholarly journals Dermatophytes in Skin, Nail and Hair among the Patients Attending Out Patient Department

2019 ◽  
Vol 16 (41) ◽  
pp. 434-437 ◽  
Author(s):  
Beena Jha ◽  
Sabina Bhattarai ◽  
Jyotshna Sapkota ◽  
Manisha Sharma ◽  
Chandra Prakash Bhatt
Keyword(s):  
Laboratory Diagnosis ◽  
Cross Sectional Study ◽  
Age Group ◽  
Aetiological Agent ◽  
Cross Sectional ◽  
Female Ratio ◽  
Direct Microscopy ◽  
Male Predominance ◽  
Medical College ◽  
Patient Department

Background: Dermatophytosis are the most common types of cutaneous fungal infection seen in human and animals affecting skin, hair and nails caused by dermatophytes. The diagnosis of dermatophytes is based on the clinical observation and laboratory diagnosis by direct microscopic examination and fungal cultures. The present study is undertaken to isolate different type of dermatophytes causing fungal infection.Methods: A prospective cross-sectional study design was used in a total of 90 clinically suspected cases of dermatophytic infection attending the out patient department of Kathmandu Medical College and Teaching hospital (KMCTH). Skin scraping, hair and nail samples were collected from the patients and were processed by direct microscopy and culture using standard protocol. Dermatophytes were identified based on the microscopic arrangement of microconidia and macroconidia.Results: Dermatophytosis was more common in the age group of 21-40 years and was more predominant among male with male to female ratio of 1.7: 1. Among the total clinically suspected cases of dermatophytosis, 53 were positive in direct microscopy and only a total of 20 were positive by culture. Most common clinical type observed in our study was Tinea corporis(25%) followed by Tinea cruris. Trichophyton rubrum(50%) was the commonest aetiological agent in majority of clinical types followed by Trychophyton mentagrophytes(35%). Conclusions: The study highlighted T. corporis followed by T. cruris and T. unguim as the most common clinical pattern of dermatophytosis with a male predominance and 21-40 years being the most affected age group. T. rubram was the most common aetiological agent causing dermatophytosis.Keywords: Dermatophytes; dermatophytosis; epidermophyton; tinea; trychophyton.

scholarly journals A cross-sectional study on determinants of immunization coverage in urban area Chidambaram, Tamil Nadu

2021 ◽  
Vol 8 (5) ◽  
pp. 2309
Author(s):  
D. P. Lakshmi Priya ◽  
P. Kalyani ◽  
B. Sindhu Bala
Keyword(s):  
Tamil Nadu ◽  
Immunization Coverage ◽  
Cost Effective ◽  
Healthcare Facility ◽  
Cross Sectional Study ◽  
Child Health Services ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Number Of Children

Background: Immunization is one of the cost effective measures preventing approximately 2 to 3 million deaths in young children every year. Inspite of the progress in vaccination coverage challenges still remain for underserved and inaccessible children. It is therefore essential to evaluate the immunization coverage at periodic intervals and improve coverage in vulnerable areas.Methods: A cross-sectional study was conducted among 152 children aged 12 to 42 months in urban Chidambaram from September to October 2018. We collected details regarding immunization from vaccination card or mother’s recall. A pretested semi-structured proforma was used to collect sociodemographic variables. Data were collected, compiled and tabulated using microsoft excel and analyzed using SPSS 20.0 version.Results: Complete immunization coverage was 80.3% and 19.7% were partially immunized. Lack of awareness is the major reason for failure of full immunization (63.3%). Immunization coverage was higher when parents studied up to higher secondary or graduates (mother 91.3%, father 87.5%, p value 0.01), father do skilled jobs (91.9%, p value 0.02), among first birth ordered children (88.3%, p value 0.01), children born in healthcare facility and among mothers who received antenatal care during pregnancy (80.8% each, p value 0.04).Conclusions: Lack of awareness, parents’ literacy and occupation, place of birth, antenatal services and number of children in the family are important determinants of immunisation coverage. Apart from strengthening of infrastructure for better delivery of mother and child health services other issues also need to be addressed for better immunization practices.

scholarly journals JUNK FOOD ADDICTION AMONG MEDICAL STUDENTS IN RAWALPINDI- A KAP STUDY

2020 ◽  
Vol 4 (2) ◽  
pp. 1-7
Author(s):  
Nosheen Zaidi ◽  
Najma Javed
Keyword(s):  
Food Addiction ◽  
Cross Sectional Study ◽  
Male Students ◽  
Dietary Habit ◽  
Junk Food ◽  
Healthy Foods ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Public Health Strategies

Use of high calorie junk foods has increased dramatically in the recent past, leading to many social and health problems. Pakistan is facing the same situation. It is therefore, a strong need to develop public health strategies targeting to reduce intake of junk food. Study was conducted over period of 9 months (from January to August 2013) among students of Foundation University Medical College. It was a cross sectional study. A total of 445 students were selected. Response rate was 85.5%. Male to female ratio was 1: 1.7. The percentage of girls was more because there are more female students as compared to male students in every class. Age ranged from 17-29 years with mean of 21 years. The percentage of Boarders to Non-boarders was 41% (182) and 59% (262) respectively.38% (169) of students take junk food daily while 39% (174) on weekly basis. Majority 169 (38%) students prefer home deliveries; while 111 students (25%) prefer to dine in. However 37% like to take food with them. Knowledge about non communicable diseases was quite good however the term ‘junk food’ was not accurately defined by all students. Around 200 (23%) of students spend Rs. 1000 for buying junk food weekly, while 142 (32%) spend more than 1000 rupees.191 (43%) of the students have experienced an increase in junk food frequency since they are living in hostel, 174 (39%) have no idea or didn’t notice any change whereas 80 (8%) had no change in their dietary habit despite of being living in hostel. On consuming junk food, 209 (47%) of the students have a pleasant feeling while majority 249 (56%) have no elevation of mood following junk food. Most (231, 52%) of the students said that they are not addicted to junk food. Junk food is quickly replacing the traditional home made and healthy foods. Health Education sessions regarding risks and hazards associated with junk food consumption must be done regularly in schools/ colleges to prevent junk food epidemic especially among youth.

scholarly journals An Orthopedic-, Surgical-, and Epidemiological-Based Investigation of Leprosy, in the Tamil Nadu State of India

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Jason Samona ◽  
Scott Samona ◽  
Cameron Samona ◽  
S. Gopalakrishnan ◽  
P. Shekhar ◽  
...  
Keyword(s):  
Tamil Nadu ◽  
Treatment Options ◽  
College Teaching ◽  
Past Research ◽  
Epidemiological Survey ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Tamil Nadu State ◽  
Data Points

No other research paper has ever been written about leprosy in this manner. The orthopedic and surgical implications, as well as the functional debility caused by the disease, have not been previously explained by past research as they have in such a comprehensive manner in this paper. The results of this study have regional and global implications as they pertain to disease pathology, risk factor recognition/disease prevention, and treatment. This paper is a unique, in that it also serves as a combination of a review of the current medical literature, as well as an epidemiological survey of the disease in a region of the world which has never been researched in the past. Clinical data points to the possibility of a new strain of the disease. This information is of significance because it effects prevention and improved treatment of the disease, which leads to devastating sequela. This was a cross-sectional study involving subjects diagnosed with leprosy in the Chengalpet region of the Kancheepuram District, of the Tamil Nadu state of India. The study was performed at the Tamil Nadu Medical College Teaching Hospital and Research Center. This study included various physical examinations, observation and survey of lesions, questionnaires in regard the debilitating orthopedic and medical effects of the disease, as well as treatment options.

scholarly journals Comparison of early appendectomy versus conservative management for appendicular lump at Tertiary Care Hospital.

2020 ◽  
Vol 27 (09) ◽  
pp. 1818-1822
Author(s):  
Zulfiqar Ali Imtiaz Memon ◽  
Mashooque Ali Khowaja ◽  
Inayat Ali Zardari ◽  
Altaf Hussain Ghumro ◽  
Farkhanda Jabeen Dahri ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Wound Dehiscence ◽  
Cross Sectional Study ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Negative Results ◽  
Clinical Presentations

Objectives: The purpose is to compare two options of management of appendicular lump in order to sort out the better one for the benefit and betterment of populace. Study Design: Cross Sectional study. Setting: Peoples Medical College Hospital Nawabshah. Period: 2016 August to August 2018. Material & Methods: Total 50 patients of appendicular lump were included in this research. All patients were divided into 2 groups. Group 1 included those patients undergoing emergency appendectomy. They were admitted, optimized and the required treatment was initiated. Results: Of total 50, 30(60%) were male and 20(40%) were females. Age was between 14 to 51 years. All patients presented with different clinical presentations. Pain in RIF was in 42(84%) patients whereas 47(94%) patients presented with lump in RIF. 20(40%) patients were operated for appendectomy in emergency and 5(10%) patients for right hemi-colectomy. Histopathological diagnosis was inflammation in 24(48%) patients and 1(2%) resulted in cecal tumor. Infected wound was found in 15 (30%) patients, hematoma in 3 (6%), wound dehiscence in 1(2%) and also cecal fistula in 1 (2%). Conclusion: Conservative treatment is better option to treat appendicular lump with least negative results.

scholarly journals Trend of ABO and Rh Blood Group among the Students of Community Based Medical College Bangladesh

2017 ◽  
Vol 6 (2) ◽  
pp. 12-14
Author(s):  
Nilufar Begum ◽  
Amdadul Haque ◽  
Fatema Akhter Tumpa
Keyword(s):  
Blood Group ◽  
Cross Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio ◽  
Group B ◽  
Safe Blood ◽  
Blood Grouping

This cross sectional study was done at department of Transfusion Medicine in Community Based Medical College (CBMCB) to know the Prevalence of ABO blood group and Rh group systems among the students selected for admission into CBMCB. Sample size was 555. Male female ratio was 67:33 with mean age was ±19 years. Maintaining aseptic precaution blood samples were collected by venepuncture with disposable syringe without anticoagulant. Antigen-antibody agglutination test was done in slide method for ABO and Rh(D) blood grouping by mixing individual blood sample with Anti A, Anti -B, Anti-D human antisera. Results were taken by visually and under microscope in low power. Blood group differs person to person due to genetically determined antigen. This study showed highest frequency of blood group B (33.5%) followed by O (32.5 %), A (23.37%) and AB (10.63%) in ABO system and In Rhesus system, frequency of Rh-positive was 97.12% and Rh-negative was 2.88%. Results were comparable with different foreign studies. Fair blood grouping assist the safe blood transfusion and reduce the morbidity and mortality considerably. CBMJ 2017 July: Vol. 06 No. 02 P: 12-14

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