scholarly journals Prevalence of Anti-Red Cell Antibodies in Repeatedly Transfused Patients

2019 ◽  
Vol 14 (1) ◽  
pp. 73-77
Author(s):  
Masuma Ahmed Salsabil ◽  
Ashesh Kumar Chowdhury ◽  
Debashish Saha ◽  
Arif Ahmed Khan ◽  
Sazia Sultana
Keyword(s):  
Haemolytic Anaemia ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Red Cell ◽  
Cross Sectional ◽  
Transfusion Therapy ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio ◽  
Immune Haemolytic Anaemia

Introduction: The development of anti-RBC antibodies (alloantibodies and/or autoantibodies) can significantly complicate transfusion therapy, particularly in patients needed repeated transfusion. Objectives: To find out the prevalence of alloantibodies and autoantibodies in repeatedly transfused patients so that serious hazards due to immune reaction may be avoided. Materials and Methods: This descriptive cross-sectional study was carried out in Department of Immunology, BIRDEM and Armed Forces Institute of Pathology (AFIP) during the period of July 2015 to June 2016. Total 370 patients who had received at least five units of transfusions were enrolled in this study but known patients of auto immune haemolytic anaemia, patients in whom antibody was previously detected and pregnant women were excluded from the study. Blood grouping and Direct Anti-globulin Test (DAT) were performed with cell suspension using a poly-specific Coombs reagent. In cases of a positive DAT, further investigation using specific monoclonal reagents to detect IgG or a complement (C3d) was carried out. Serum was used to detect red cell alloantibodies using standard blood bank methods. Antibody identification was performed in antibody screening positive samples using red cell Identicells. Results: Maximum 132 (35.7%) patients were in the age group 1-10 years. The male-female ratio was 1.2:1. Among 370 total patients 290 were HHA and 80 were non-HHA. Antibody was detected in only 17(4.59%) patients. Among the Hereditary Haemolytic Anaemia (HHA) patients it was 11 (3.79%) but among the non-HHA patients it was 6(7.5%). Out of 8 auto-antibodies, 5 were anti IgG followed by 3 were anti C3d. Out of 14 alloantibodies, 4(28.6%) were anti E, 3(21.4%) were anti K and in 3(21.4%) cases specificity of alloantibody was not detected. Conclusion: Prevalence of anti-RBC antibodies was not so uncommon in multiple transfused patients. Journal of Armed Forces Medical College Bangladesh Vol.14(1) 2018: 73-77

scholarly journals Trend of ABO and Rh Blood Group among the Students of Community Based Medical College Bangladesh

2017 ◽  
Vol 6 (2) ◽  
pp. 12-14
Author(s):  
Nilufar Begum ◽  
Amdadul Haque ◽  
Fatema Akhter Tumpa
Keyword(s):  
Blood Group ◽  
Cross Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio ◽  
Group B ◽  
Safe Blood ◽  
Blood Grouping

This cross sectional study was done at department of Transfusion Medicine in Community Based Medical College (CBMCB) to know the Prevalence of ABO blood group and Rh group systems among the students selected for admission into CBMCB. Sample size was 555. Male female ratio was 67:33 with mean age was ±19 years. Maintaining aseptic precaution blood samples were collected by venepuncture with disposable syringe without anticoagulant. Antigen-antibody agglutination test was done in slide method for ABO and Rh(D) blood grouping by mixing individual blood sample with Anti A, Anti -B, Anti-D human antisera. Results were taken by visually and under microscope in low power. Blood group differs person to person due to genetically determined antigen. This study showed highest frequency of blood group B (33.5%) followed by O (32.5 %), A (23.37%) and AB (10.63%) in ABO system and In Rhesus system, frequency of Rh-positive was 97.12% and Rh-negative was 2.88%. Results were comparable with different foreign studies. Fair blood grouping assist the safe blood transfusion and reduce the morbidity and mortality considerably. CBMJ 2017 July: Vol. 06 No. 02 P: 12-14

scholarly journals Re-evaluation of Smear Negative Suspected Tuberculosis Patients by GeneXpert

2019 ◽  
Vol 13 (2) ◽  
pp. 3-6
Author(s):  
Md Fashiur Rahman ◽  
Md Jahangir Alam ◽  
Md Abu Sayeed Sarker ◽  
Md Abdul Alim ◽  
Yoshitsugu Matsumoto ◽  
...  
Keyword(s):  
Armed Forces ◽  
Laboratory Diagnosis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Sputum Microscopy ◽  
Suspected Tuberculosis ◽  
Effective Role ◽  
Smear Negative

Introduction: Tuberculosis (TB) is one of the major public health problems. Sputum microscopy even today is considered as most important laboratory diagnosis of TB though its negative result does not exclude tuberculosis. Objective: To evaluate the smear negative suspected TB patients by GeneXpart. Materials and Methods: This descriptive cross-sectional study was conducted in Surya Kanto Hospital, Mymensingh from September 2014 to September 2016.  Total 300 suspected TB patients were selected and sputum microscopy was performed then re-evaluation of the smear negative cases was carried out by GeneXpert. Results: The mean age of the patients was 38.87 ± 13.78 years with a male to female ratio 2.1: 1 and 86% was in economically productive age of life. About 13.1% smear negative suspects were diagnosed as TB positive by GeneXpert. Conclusion: GeneXpert played effective role to re-evaluate the smear negative TB cases. So, GeneXpert may be recommended routinely for TB detection. Journal of Armed Forces Medical College Bangladesh Vol.13(2) 2017: 3-6

scholarly journals Professionalism among Intern Doctors of Different Medical College Hospitals in Bangladesh

2017 ◽  
Vol 7 (2) ◽  
pp. 17-22
Author(s):  
Syed Golam Samdani ◽  
Tahmina Begum
Keyword(s):  
Professional Competence ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Attitude And Practice ◽  
Significant Difference ◽  
Male Female Ratio ◽  
The Status

This descriptive cross-sectional study was conducted to explore the status of professionalism regarding knowledge, attitude and practice among intern doctors of different medical college Hospitals in Bangladesh. Study period was July 2015 June 2016.Sample size was 300 and convenient sampling technique was adopted. Study was carried out among all Bangladeshi intern doctors of 4 governments and 2 non-governments selected medical college Hospitals of Dhaka and outside Dhaka. Total 300 intern doctors responded to a self-administered questionnaire. Male female ratio was almost 1:1. Concept of professionalism and level of knowledge regarding its various aspects are not satisfactory in large extends. But attitude towards most of the major principles of professionalism are as much as positive like USA and UK physicians. However, regarding honesty with patients, one statement like physicians should disclose all significant medical errors to affected patients and/or guardians, only 36.9% agreed with this. Similarly, only 43% agreed the statement of re-certification examination to maintain professional competence. Regarding attitude and practice of major attributes & responsibilities of professionalism there is no significant difference (p>0.05) between male and female intern doctors working in different medical college hospitals; but regarding practice there is a significant difference (p<0.05) among intern doctors working in government and non-government hospitals. This study recommended that institutional agreement should be on a definition, setting expectations & curriculum framework regarding professionalism to increase scope of teaching & learning in our undergraduate & post-graduate students.Bangladesh Journal of Medical Education Vol.7(2) 2016: 17-22

scholarly journals Clinicopathological Study on Hypopharyngeal Carcinoma in Dhaka Medical College Hospital

2016 ◽  
Vol 21 (2) ◽  
pp. 85-89
Author(s):  
Md Nazmul Islam ◽  
Dipankar Lodh ◽  
Mohammad Mamun Siddiqui ◽  
AF Mohiuddin Khan ◽  
Kazi Meherunnesa
Keyword(s):  
Neck Surgery ◽  
Cross Sectional Study ◽  
Neck Mass ◽  
Medical College Hospital ◽  
Hypopharyngeal Carcinoma ◽  
College Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio

A Cross-Sectional Study was carried out from July 2006 to June 2007 at Department of Otolaryngology and Head-Neck Surgery of Dhaka Medical College Hospital, Dhaka. Data was collected from 150 patients with histologically diagnosed Hypopharyngeal carcinoma. Results of this study showed that hypopharyngeal carcinoma affects more in fifth (36.7%) and sixth (27.4%) decades of life. It was found that male were highly predominant to develop hypopharyngeal carcinoma and male female ratio was 9:1. People with lower educational level were found to be affected more by hypopharyngeal carcinoma. In this study 86 percent patients had history of smoking. Mean duration of smoking was 38.0±23.6 years. This study found that the key symptoms of hypopharyngeal carcinoma was dysphagia, pain and neck mass. In this study 83.5 percent patients presented with palpable lymph node and most (76.6%) of them were in level II. Pyriform fossa was found to be the commonest site (83.3%). In this study all malignancy in hypopharynx was histopathologically squamous cell carcinomaBangladesh J Otorhinolaryngol; October 2015; 21(2): 85-89

scholarly journals An Association of Serum ferritin and SGPT Level in Transfusion dependent Thalassaemia major Patients-A Cross Sectional Study

2017 ◽  
Vol 8 (1) ◽  
pp. 170-173
Author(s):  
Farida Parvin ◽  
Bepasha Naznin ◽  
Tanzila Tabib Chowdhury ◽  
AFM Ashik Imran ◽  
MST Laizuman Nahar ◽  
...  
Keyword(s):  
Serum Ferritin ◽  
Cross Sectional Study ◽  
Study Data ◽  
Thalassaemia Major ◽  
Sectional Study ◽  
Cross Sectional ◽  
Transfusion Therapy ◽  
Female Ratio ◽  
Medical College ◽  
Excess Iron

Background : The Thalassaemia is an inherited haemoglobulin disorder causes hemolytic anemia which usually requires life-long blood transfusion therapy. Therefore transfusion dependent thalassaemia major patients suffer from the effect of deposition of excess iron in the liver, heart and endocrine glands.Objective : The aim of present study was to find out the association of serum ferritin and SGPT in transfusion dependent thalassaemia major patient.Methodology : This cross sectional study was carried out in Day care unit (DCU) of Transfusion Medicine department, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, during January 2014 to December 2014. Total of 110 clinically diagnosed Thalassaemia major (TM) between (5-35 years) cases of either sex from the above mentioned department attending the DCU were selected purposively for this study. Data were collected on clinical examination findings, laboratory investigations, ABO and Rh Blood Group, Serum ferritin and SGPT (Serum glutamic pyruvic transaminase) after taking informed consent.Results : The following observations and results were obtained in this study. The mean age was found 17.15±8.77 years with range from 5 to 35 years and male to female ratio was 1.2:1 (male 59 and female 51). Sixty eight (68.0%) patients came from rural area, 43.6% patients were student, 77.3% patients had completed primary education, 57.3% of the patients came from middle class family and 72.7% patients were unmarried. About 46.4% of the patients had moderate anaemia, 28.2% had jaundice, 79.1% had hepatomegaly, 82.7% had splenomegaly and 30.9% had complication due to iron overload. Mean haemoglobulin (Hb%) was found 6.65±1.63 gm/dl, mean serum ferritin was found 3785±17637 ?g/L and mean SGPT was found 134.8±77.94 U/L. There was a significant positive correlation (r=0.259; p=0.006) between serum ferritin and SGPT.Conclusion : Considering the study result it can be concluded that there is a positive significant correlation between serum ferritin with SGPT level.Northern International Medical College Journal Vol.8(1) July 2016: 170-173

scholarly journals Risk Factors, Pattern and Outcome of Motorcycle-associated Head Injury in Sokoto: An Analysis of 184 Cases

2021 ◽  
Author(s):  
Henry Olayere Obanife ◽  
Nasiru Jinjiri Ismail ◽  
Ali Lasseini ◽  
Bello B. Shehu ◽  
Ega J. Otorkpa
Keyword(s):  
Developing Countries ◽  
Head Injury ◽  
Road Traffic ◽  
Negative Impact ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Incidence And Mortality ◽  
Male Female Ratio ◽  
Significant Negative Impact

Abstract Background Road traffic accident (RTA) is the eighth leading cause of death worldwide. Motorcycle-associated head injury is the leading cause of road traffic associated morbidity and mortality in developing countries. Even though the incidence and mortality of head injury from motor cycle crash is on the increase in developing countries, especially in the African continent, most of the studies published in the literature on this subject matter took place in the developed Western countries. Methods This is a retrospective cross-sectional study of data from patients managed in our institution between December 2014 and November 2016. Results One hundred and eighty-four patients were analyzed. None of the patients used safety helmet for protection. The mean age was 27.6 ± 17.2 years with male female ratio of 6.7:1. Lone crash by cyclists and collisions accounted for 66.8% and 33.1% of the cases, respectively. Passengers and riders comprised 75% of the patients, while 25% were vulnerable pedestrians. The most frequently abused substance by the patients was tramadol (65.52%). Severe head injury and pupillary abnormality were found in 23.9% and 45.5% of the patients, respectively. Cranial CT scan showed abnormalities in 40.2% of the patients. Surgery was done in 28.3% of the patients with mortality rate of 20.7%. Conclusions The use of motorcycle as a mean of transportation has caused significant negative impact on the society. Young people, who constitute the workforce, are majorly affected, and this invariably leads to a serious economic burden on the concerned families and communities.

scholarly journals Role of Squash Cytology in Intraoperative Diagnosis of Meningioma

2021 ◽  
Author(s):  
Gowri Prakasam ◽  
K Karkuzhali ◽  
Veeraraghavan Gurusamy
Keyword(s):  
Tamil Nadu ◽  
Frozen Section ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Histopathological Diagnosis ◽  
Suspected Case ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Cost Effective Technique

Introduction: Primary Central Nervous System (CNS) tumours constitute less than 2% of overall cancers in adults and are the second most frequently encountered tumours in children. Meningiomas form 24-30% of primary intracranial tumours. Most intrinsic brain tumours are soft and gelatinous in consistency, smear preparation can readily made which gives excellent cytological details when compared to frozen section as the latter produces ice crystal artifacts. Aim: To assess the diagnostic utility of squash cytological evaluation of meningiomas and its comparison with final histopathological diagnosis. Materials and Methods: The cross-sectional study was done at Thanjavur Medical College, Thanjavur, Tamil Nadu, India for period of three years from January 2015 to December 2017. Total of 54 clinically diagnosed and radiologically suspected case of meningiomas were selected. Smears were prepared from the biopsy samples sent in normal saline and stained by Haematoxylin and Eosin (H&E) method. The cytological features were noted and matched with biopsy findings. Descriptive statistics were used to analyse the results. Results: Total of 54 squash smears with male to female ratio was 1:1.5. Maximum number of cases were seen between 41- 50 years followed by 51-60 years. Complete concordance was obtained in 51 cases (94.44%) and partial concordance was noted in a case due to underestimation of malignancy grade in squash cytology. Out of 54 cases, two cases were found to be discordant with final histopathological diagnosis. Conclusion: Intraoperative squash cytology is easy, rapid, reliable and cost-effective technique for neurosurgical consultation with fairly high accuracy in diagnosing meningiomas.

scholarly journals Prevalence of Metabolic Syndrome among Border Guard Bangladesh Personnel

2020 ◽  
Vol 14 (2) ◽  
pp. 97-100
Author(s):  
Md Abdul Wahab ◽  
Md Mustafizur Rahman ◽  
Md Abdur Razzak ◽  
Md Habibur Rahman ◽  
Mimi Parvin ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
International Diabetes Federation ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Age Group ◽  
Metabolic Abnormalities ◽  
Sectional Study ◽  
Ethnic Population ◽  
Cross Sectional ◽  
Medical College

Introduction: Metabolic syndrome (MetS) is a multifaceted syndrome comprises a cluster of metabolic abnormalities including hypertension, central obesity, insulin resistance, dyslipidemia, and is strongly associated with developing diabetes mellitus and cardiovascular diseases. Prevalence of MetS differs in different ethnic population by using different definition. Objectives: To determine the prevalence of the MetS and its component risk factors among Border Guard Bangladesh (BGB) personnel working in Chattagram Hill Tract (CHT). Materials & Methods: This descriptive cross-sectional study was conducted from October 2016 to February 2018 among 1455 male BGB personnel aged between 40 to 59 years and working in CHT of Bangladesh. Study subjects were selected at BGB hospital, Guimara, Khagrachari. The new International Diabetes Federation (IDF) guidelines were used to identify MetS. Detail history, clinical examination, anthropometry and blood pressure (BP) were measured and fasting plasma glucose (FPG) and lipid profile were assessed. Results: Among the 1455 respondents’ BMI, waist circumference, systolic and diastolic BP were found more than normal in 34.1, 37.7, 16.4% and 12.3% respectively. Biochemical parameters including FPG, TC, TG, and LDL-C was raised in 28.7%, 49.8%, 52.2% and 37.7% of respondents respectively. HDL-C was found decreased in 26.9% respondents. Age wise prevalence of MetS for age group 40-44, 45-49, 50-54 and 55- 59 years were found 21.3%, 21.7%, 24.1% and 26.1% of the respondents respectively. The overall prevalence of MetS was found 22.4%. Conclusion: The prevalence of the MetS in BGB personnel was found 22.4%. Appropriate measure should be taken to lower the MetS cases. Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 97-100

scholarly journals Treatment of Chalazian: a Comparative Cross-sectional Study

2019 ◽  
Vol 1 (1) ◽  
pp. 5-9
Author(s):  
Binita Bhattarai ◽  
Koshal Shrestha ◽  
Sushila Patel ◽  
Laxmi Devi Manandhar ◽  
Rosy Karki ◽  
...  
Keyword(s):  
Triamcinolone Acetonide ◽  
Complete Resolution ◽  
Cross Sectional Study ◽  
Meibomian Gland ◽  
Intralesional Injection ◽  
Cross Sectional ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Eye Symptoms

Background: Chalazion is a common eyelid disease caused by plugged meibomian glands and chronic lipogranulomatous inflammation. It can affect individuals of all ages and may cause local eye symptoms such as irritation and inflammation and cosmetic disfigurement. There are mainly three methods of treating chalazion: Intralesional Triamcinolone Acetonide (0.1-0.3 ml of 40mg/ml), Incision and Curettage and Conservative Treatment (hot compression +lid hygiene + antibiotic ointment) to the affected eyelid. To comparing which method is the best this study has been carried out Methodology: Patients with chalazion presenting to OPD from 15 March to 15 July 2017 were included in the study. They underwent any of the three procedures according to their choice. Follow up visit was done at two weeks to determine effectiveness in terms of reduction of size or complete resolution of the chalazion. Results: Out of 112 patients enrolled in study 65(58%) were females and 47(42%) were male with a male: female ratio of (0.7:1). The mean age of involvement was 25.7years (SD 10.3). At 2 weeks follow up there was complete resolution in incision and curettage (I and C) group 77 %( 41/53) and in Triamcinolone Acetonide (TA) injection group 63 %( 20/32). Pearsons correlations showed that I and C were superior to any other forms of intervention for any size of chalazion followed by intralesional injection of TA. Conclusion: Among the three methods, Incision and Curettage remained the best choice for treatment of chalazion followed by triamcinolone acetonide injection but may need multiple injections. Keywords: Chalazion, Intralesional Triamcinolone, Incision and Curettage, Meibomian Gland

The Social Capital among Elderly Population of Chandigarh: Cross Sectional Study

Healthline ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 29-36
Author(s):  
Kiranjit Kaur ◽  
Naveen Krishan Goel ◽  
Manoj Kumar Sharma ◽  
Navpreet Singh ◽  
Mamta Bishnoi ◽  
...  
Keyword(s):  
Social Capital ◽  
Elderly Population ◽  
Social Trust ◽  
Cross Sectional Study ◽  
Elderly Subjects ◽  
Cross Sectional ◽  
Female Ratio ◽  
The Social ◽  
Male Female Ratio ◽  
The Status

Introduction: Social capital is defined as social cohesion among communities. This refers to processes between people which establish network, social trust and co-operation and mutual benefit. The present study was conducted to know the status of social capital among elderly population of Chandigarh city, India. Methods: The study was conducted from January to April 2017. The study was community based using convenience sampling. A total of 300 elderly subjects were selected for interview from the electoral rolls. The survey instrument was modified Onyx and Bullen scale consisting of 30 items with responses on likert scale from 1-4. Results: Mean age of respondents was 66.47 years. Male: Female ratio was 1.4:1. 45.7% owned their residence whereas 54.3% lived as tenants. Social capital score of majorities of elderly was good (63.7%) followed by average (19.3%).Highest mean scores were received for questions namely: would you help someone if their vehicle breaks down (3.03±0.69), do you agree to helping yourself when you help others (3.15±0.78) and have you visited your neighborhood in the past week (3.01±0.82). Poorest scorewere received for questions: while on shopping, are likely to run into friends (1.11±0.53) and have you done a favor for a sick neighbor in last 6 months (1.33±0.53). Conclusion: Social capital status among elderly of Chandigarh city was good andhigher scores were seenamong males. Highest mean scores were seen in factor 4 (proactivity in social context) and lowest among family and factor 5 (friend’s connections).

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