scholarly journals Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea

2021 ◽  
Author(s):  
Shruthi Amalagondhi Manjunatha ◽  
Pradeep Addagadde Venkataramana ◽  
. Rajshekar ◽  
Srinivas Siddegowda
Keyword(s):  
Visual Acuity ◽  
Calotropis Procera ◽  
Corneal Oedema ◽  
Ocular Toxicity ◽  
Accidental Exposure ◽  
Calotropis Gigantea ◽  
Body Sensation ◽  
Department Of Ophthalmology ◽  
Ocular Morbidity ◽  
Common Sign

Introduction: Calotropis is a member of the milkweed or Asclepiadeae family. The latex of Calotropis gigantea (C gigantea) contains cardiac glycosides, fatty acids and calcium oxalate. The sap of Calotropis procera (C procera) produces acidic latex. Toxic effect of latex manifests after a few hours with diminution of vision due to corneal oedema with folds in Descemet’s membrane. Aim: To evaluate the ocular toxicity by the latex of calotropis procera and calotropis gigantea due to accidental exposure. Materials and Methods: This was a prospective observational study conducted for a duration of six months (September 2018 to February 2019) on 18 patients with alleged accidental exposure to calotropis latex. The patients were examined in the Department of Ophthalmology, Mandya Institute of Medical Sciences (MIMS), Mandya, Karnataka, India. After a thorough saline wash under topical anaesthesia, visual acuity was measured by using Snellen’s chart, then patients were subjected for slit lamp biomicroscopy examination, Intraocular Pressure (IOP) measurement and undilated fundus examination and the findings were noted. Demographic details like age and sex, activity at time of injury, mode of injury were noted and follow-up was done for a period of 30 days. Data were analysed using Epi info software and descriptive statistics like mean and percentage were calculated. Results: Total 18 patients reported with calotropis associated eye toxicity, among which 11 (61.1%) were of C gigantea and seven (38.9%) were of C procera. Out of total, seven (38.9%) were males and 11 (61.1%) females. A total of 14 (77.8%) patients presented within 24 hours of injury. Eleven (61.1%) patients had involvement of both the eyes. The main symptoms were burning, irritation, foreign body sensation and diminution of vision. Best Corrected Visual Acuity (BCVA) varied from 6/9 to 6/60. Corneal oedema or striate keratopathy was the most common sign. Corneal oedema resolved in one week in case of C procera with use of topical corticosteroids except in three cases of C gigantea which took two weeks. Conclusion: C procera and C gigantea causes significant corneal oedema and ocular morbidity. By simple health education and occupational precaution, we can prevent ocular morbidity.

scholarly journals Dry eye syndrome and cataract surgery

2019 ◽  
Vol 72 (3-4) ◽  
pp. 105-109
Author(s):  
Stefan Brunet ◽  
Vladimir Canadanovic ◽  
Nikola Babic ◽  
Aleksandar Miljkovic ◽  
Sandra Jovanovic ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Dry Eye Syndrome ◽  
Schirmer Test ◽  
Corrected Visual Acuity ◽  
Body Sensation ◽  
Eye Symptoms ◽  
Best Corrected Visual Acuity ◽  
Dry Eye Symptoms

Introduction. Dry eye syndrome has become a common problem after ocular surgeries with a significant impact on the quality of life. Many patients, who have undergone cataract surgery, postop?eratively developed dry eye symptoms. Dry eye syndrome is one of the risk factors associated with cataract surgery. Material and Methods. The prospective study included 80 patients. We recorded the self-reported dry eye symptoms, the values of Schirmer test, tear breakup time, and best corrected visual acuity preoperatively, as well as 7 days and 1 month after the surgery. Results. A total of 80 patients were included in the study, 45 (56.2%) females and 35 (43.8%) males. The mean age of patients was 61.5 years (SD ? 6.2, range 57 - 70 years). The best corrected visual acuity at the time of surgery was 0.4 or less in 70 patients (87.5%). Most patients reported a significant improvement in visual acuity after surgery; 68 (85%) eyes achieved a best corrected visual acuity of 0.5 or higher (median 0.7; range 0.5 - 1.0). The mean tear breaking time in cata?ract patients before surgery was 12.4 sec, 7 days after the surgery it was 8.2 sec (p < 0.05) and 1 moth after the surgery 11.1 sec. The majority of patients had mild (47.5%) and moderate (33.75%) Schirmer test values. Dry eye with wetting < 5 mm after 5 minutes was found in 16.2% of patients before cataract surgery; 7 days after the surgery (p < 0.05) it was found in 23.75% of patients and one month after surgery 11.1 sec. A foreign body sensation and watery eye were the most reported symptoms before cataract surgery. Seven days after the surgery foreign body sensation was present in 48.75% and watery eyes in 40% of patients. Conclusion. Significant increase in dry eye symptoms after cataract surgery was found with increasing age. Self reported dry eye problems are more common in patients with lower Schirmer test and best corrected visual acu?ity values before cataract surgery. Patients with concomitant dry eye disease require preoperative and postoperative treatment of dry eye to prevent aggravation of the existing symptoms that may affect the visual outcome after cataract surgery.

scholarly journals Hospital based study of demography and clinical picture of vernal keratoconjunctivitis

2017 ◽  
Vol 6 (1) ◽  
pp. 65 ◽  
Author(s):  
Maneesha Sethi ◽  
Ridham Nanda ◽  
Amarjeet Singh Bali ◽  
P. Sadhotra
Keyword(s):  
Mixed Type ◽  
Clinical Presentation ◽  
Signs And Symptoms ◽  
Vernal Keratoconjunctivitis ◽  
Female Ratio ◽  
Northern India ◽  
Department Of Ophthalmology ◽  
Male Female Ratio ◽  
History Of ◽  
Ocular Morbidity

Background: Vernal Keratoconjunctivitis (VKC) is common cause of ocular morbidity in children living in tropical countries. Its diagnosis is based on signs and symptoms of the disease. The study was undertaken to stress upon the demography and clinical presentation of VKC.Methods: Retrospective pre-formed proforma of 155 patients of VKC, who were detected at random in the out - patient department of ophthalmology, ASCOMS, Jammu from May 2016 to April 2017, were analyzed.Results: Mean age at presentation was 10.31 years +4.05. The Male: Female ratio was 4.96:1. Majority of patients reported in the month of May. Mixed type of VKC was predominant. Personal or family history of allergy was seen in 5.8% of patients. Itching (100%) was commonest symptom and palpaberal papillae were commonest sign seen in 78.70% of patients.Conclusions: Clinical pattern of VKC seen in hot and dry climate of Northern India is like that seen in other parts of country.

scholarly journals Macular edema after cataract surgery in eyes with and without pseudoexfoliation syndrome

2018 ◽  
Vol 29 (5) ◽  
pp. 504-509 ◽  
Author(s):  
Lotta Ilveskoski ◽  
Claudia Taipale ◽  
Emil J Holmström ◽  
Raimo Tuuminen
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Macular Edema ◽  
Pseudoexfoliation Syndrome ◽  
National Guidelines ◽  
Aqueous Flare ◽  
Corrected Visual Acuity ◽  
Department Of Ophthalmology ◽  
Anti Inflammatory ◽  
Best Corrected Visual Acuity

Background:The purpose of the study was to identify macular edema after cataract surgery in eyes with and without pseudoexfoliation syndrome. The study was a post-hoc analysis of a randomized, double-blind, prospective single-center study. Patients were enrolled between January 2016 and October 2016 as per the national guidelines for the management of cataract in the Department of Ophthalmology, Kymenlaakso Central Hospital, Kotka, Finland.Methods:One hundred and fifty-six eyes of 149 patients undergoing routine cataract surgery. Postoperatively anti-inflammatory medication was either dexamethasone (N = 78) or diclofenac (N = 78). Spectral domain optical coherence tomography imaging and laser flare meter measurement of the anterior chamber were conducted before surgery and at the control visit 28 days postoperatively.Results:Baseline variables were comparable between eyes with pseudoexfoliation syndrome (N = 32) and those without (N = 124), except for intraocular pressure ( P = 0.002) and glaucoma medication ( P < 0.001). In patients having pseudoexfoliation syndrome, central retinal thickness increase (mean ± standard error of the mean) was 63.3 ± 35.5 μm for dexamethasone and 17.6 ± 5.8 μm for diclofenac, compared to 28.9 ± 8.0 μm ( P = NS) and 6.9 ± 1.3 μm ( P = 0.014) in eyes without pseudoexfoliation syndrome, respectively. Aqueous flare at 28 days was 25.8 ± 5.4 pu/ms for patients with pseudoexfoliation syndrome and 18.3 ± 1.8 pu/ms for those without ( P = 0.030). Best corrected visual acuity gain and best corrected visual acuity at 28 days were less in patients having pseudoexfoliation syndrome compared to those without (0.39 ± 0.07 vs 0.59 ± 0.03 decimals, P = 0.007; and 0.77 ± 0.06 vs 0.92 ± 0.03 decimals, P = 0.008, respectively).Conclusion:Eyes with pseudoexfoliation syndrome may be predisposed to an increased aqueous flare and macular edema after cataract surgery. This study outlines the need to determine the optimal anti-inflammatory medication after cataract surgery in patients with pseudoexfoliation syndrome.

scholarly journals Feasibility of using patient-reported outcome measures with visually impaired children/young people attending paediatric ophthalmology clinics

2020 ◽  
pp. archdischild-2020-318991
Author(s):  
Alexandra O Robertson ◽  
Valerija Tadić ◽  
Mario Cortina-Borja ◽  
Jugnoo Rahi
Keyword(s):  
Visual Acuity ◽  
Outcome Measures ◽  
Patient Reported Outcome Measures ◽  
Young Person ◽  
Patient Reported Outcome ◽  
Department Of Ophthalmology ◽  
Patient Reported ◽  
Paper And Pencil ◽  
Paediatric Ophthalmology ◽  
At Home

ABSTRACTObjectiveTo explore feasibility of using child/young person patient-reported outcome measures (PROMs) routinely in practice, using vision-specific instruments and paediatric ophthalmology as the exemplar.MethodsParticipants comprised patients aged 8–17 years, with visual impairment or low vision (visual acuity of the logarithm of the minimum angle of resolution (logMAR) worse than 0.3 in the better eye), attending the Department of Ophthalmology at Great Ormond Street Hospital, London, UK. All participants completed age-appropriate PROMs before attending their outpatient appointment. Half were randomly assigned to completion at home, with the choice of paper-and-pencil or electronic format. The other half were invited to complete PROMs during their hospital appointment, and randomly assigned to completion format. All participants completed a face-to-face survey exploring their attitudes and preferences. Analysis comprised survival analysis, and direct comparisons of proportions, with complementary qualitative data analysis.Results93 patients participated. 48 (98%) completing PROMs at home chose the paper-and-pencil format. Completion at home took longer than at hospital (median=20, vs 14 min, p<0.001). Visual acuity was associated with completion time (p=0.007) and missing data (p=0.03). Overall, 52 (60%) reported a preference for completion at home but there was no clear preference for format (37 (43%) preferred either format).ConclusionPROM completion at home ahead of hospital appointments may be preferable for collecting complete, high-quality datasets. Despite equipoise on preference for format, the majority of those completing at home chose the traditional paper-and-pencil format, despite impaired sight. These findings should inform implementation of child/young person PROMs into routine practice.

Comparison of real-world treatment outcomes of femtosecond laser-assisted cataract surgery and phacoemulsification cataract surgery: A retrospective, observational study from an outpatient clinic in France

2020 ◽  
pp. 112067212092576
Author(s):  
Philippe Charles Crozafon ◽  
Christine Bouchet ◽  
Monia Zignani ◽  
Ray Griner ◽  
Samuel D Foster ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Multiple Comparisons ◽  
Posterior Capsule Opacification ◽  
Dissipated Energy ◽  
Corneal Oedema ◽  
Corrected Distance Visual Acuity ◽  
Cumulative Dissipated Energy ◽  
Phacoemulsification Cataract Surgery

Purpose: This study compared real-world safety and efficacy outcomes of cataract surgery performed with LenSx femtosecond laser-assisted cataract surgery or manual phacoemulsification cataract surgery procedures. Methods: A retrospective observational study used data from anonymised electronic medical records to compare mean cumulative dissipated energy, the proportion of eyes reaching emmetropia, mean change in best-corrected distance visual acuity and the proportion of eyes with post-surgical complications, including corneal oedema and posterior capsule opacification. Results were adjusted for multiple comparisons for primary and secondary objectives. Results: Data from 811 phacoemulsification cataract surgery and 496 femtosecond laser-assisted cataract surgery procedures were analysed. Mean cumulative dissipated energy was significantly lower for femtosecond laser-assisted cataract surgery (6.5 percent-seconds) than for phacoemulsification cataract surgery (14.3 percent-seconds; p < 0.0001) procedures. More femtosecond laser-assisted cataract surgery (81.2%) procedures achieved emmetropia (⩽ 0.5 dioptre) than did phacoemulsification cataract surgery (73.5%) procedures, although this difference was not statistically significant. Mean change in best-corrected distance visual acuity and the proportion of eyes with corneal oedema, posterior capsule opacification or other complications were not significantly different between cohorts when adjusted for multiple comparisons. Conclusions: In this single-centre, single-surgeon retrospective electronic medical record database study using divide and conquer technique, femtosecond laser-assisted cataract surgery was associated with significantly lower cumulative dissipated energy when compared to manual phacoemulsification cataract surgery. This supports the hypothesis that femtosecond laser-assisted cataract surgery involves less mechanical trauma, which might lead to more consistent refractive and safety outcomes than manual phacoemulsification cataract surgery, though such outcomes were found to be comparable in this study.

Retinopathy Associated with Adjuvant Interferon in a Patient with Malignant Melanoma: A Case Report and Review of the Literature

2019 ◽  
pp. 1-7
Author(s):  
Mahmut Dogan
Keyword(s):  
Multiple Sclerosis ◽  
Visual Acuity ◽  
Side Effects ◽  
Vision Loss ◽  
Interferon Treatment ◽  
Ocular Toxicity ◽  
Review Of The Literature ◽  
Immune Mediated ◽  
Adjuvant Interferon

Interferons are kinds of proteins with immuneregulatory, antiviral and anti-proliferative functions. Interferons are widely used worldwide for the treatment of many diseases including cancer, hepatit C and immune mediated disease such as multiple sclerosis. Long-term use of interferons have some side effects. However, interferons have ophthalmologic side effects. Ocular toxicity may occur at any time during treatment. There is no association between the dose or duration of interferon treatment and ocular toxicity. Although visual acuity returns to normal in most patients when interferon is discontinued, vision loss may be permanent.

Keratoconic Bi-aspheric Contact Lenses

2016 ◽  
Vol 5 (3) ◽  
pp. 132-138
Author(s):  
Ariela Gordon-Shaag ◽  
Philip Fine ◽  
Liat Gantz ◽  
Arige Gideon-Abousaid ◽  
Gad Serero
Keyword(s):  
Visual Acuity ◽  
Contact Lenses ◽  
Case Series ◽  
Visual Stability ◽  
Wavefront Aberrations ◽  
Body Sensation ◽  
Quality Of Vision ◽  
Base Curve ◽  
Aspheric Lenses

ABSTRACT Aim This observational clinical case series examined patients with keratoconus (KC) fit with keratoconic bi-aspheric (KBA) lenses to assess visual acuity (VA), wavefront aberrations, physiological fitting, subjective comfort, and manufacturer's fitting guidelines. Materials and methods Seven adult patients (11 eyes, four females, mean age: 34.15 ± 14.12) with nipple cones from the Hadassah Academic College contact lens clinic (Jerusalem, Israel) were fit with KBA lenses by modifying the initial base curve (BC) to obtain an acceptable physiological fit. The uncorrected and corrected distance (D) and near (N) Snellen VA and the ocular wavefront measurements, and responses to a self-administered five-point scale questionnaire were compared after 2 weeks of wear using paired two-tailed t-test or Mann-Whitney U test, as appropriate. Results Visual acuity and total root mean square (RMS) improved significantly with the lenses (DVAuncorrected = 0.04 ± 0.02, DVAcorrected = 0.66 ± 0. 22, NVAuncorrected = 0.34 ± 0.30, NVAcorrected = 0.95 ± 0.12). Subjects reported an average of 7.0 ± 2.7 hours of wear daily, with good scores in visual stability, satisfaction with VA and quality of vision, improvement of mood and quality of life, and low scores in foreign body sensation, pain, red eye, and itching during wear, and difficulty with lens removal. An average of two BC modifications from the diagnostic lens were necessary (0.16 mm steeper in nine eyes, 0.27 mm flatter in two eyes). Conclusion Keratoconic bi-aspheric lenses can provide 7 hours of comfortable wear, significantly improved VA and total RMS aberrations, alongside subjective satisfaction. Base curve modifications can be reduced by fitting a diagnostic lens 0.75 mm steeper than the flattest keratometry reading. How to cite this article Gantz L, Gordon-Shaag A, Gideon-Abousaid A, Serero G, Fine P. Keratoconic Bi-aspheric Contact Lenses. Int J Kerat Ect Cor Dis 2016;5(3):132-138.

Surgical management of pterygium in a rural hospital using bare sclera versus conjunctival autograft technique

2017 ◽  
Vol 5 (5) ◽  
pp. 2076
Author(s):  
Dinesh P. ◽  
Sundip Shenoy ◽  
Nidhi Pandey ◽  
Pavan Kumar Reddy D.
Keyword(s):  
Visual Acuity ◽  
Connective Tissue ◽  
Medical Sciences ◽  
Visual Axis ◽  
Recurrence Rates ◽  
Conjunctival Autograft ◽  
Corrected Visual Acuity ◽  
Department Of Ophthalmology ◽  
Best Corrected Visual Acuity ◽  
Conjunctival Autografting

Background: Pterygium is defined as a triangular fibrovascular subepithelial ingrowth of degenerative bulbar conjunctival tissue over limbus onto the cornea. Commonly seen among farmers, fishermen, stone cutters and welders. Both blue and ultraviolet light have been implicated in its causation. Histologically the true Pterygium shows elastotic degeneration of the subconjunctival connective tissue. Pterygium warrant treatment when they encroach the visual axis, induces significant astigmatism or become cosmetically bothersome. My present study was undertaken to evaluate the efficacy, safety and recurrence rates of conjunctival autograft and bare sclera techniques in treatment of progressive true pterygium in a rural hospital.Methods: The prospective study was done in the Department of Ophthalmology, Adichunchanagiri Institute of Medical Sciences, B.G Nagara, Mandya District, Karnataka, India. The study was conducted for a period of 18 months. About 70 patients who presented with progressive pterygium were included in the study.Results: In our study pterygium recurred in 10 cases (14.28%), among which pterygium recurred in 8 cases (22.85 %) using bare sclera technique and in 2 patients (5.71%) using conjunctival autograft technique, best corrected visual acuity remained stable in 37 cases (52.85 %), improved in 33 cases (47.14 %) and worsened in none (0%) of the cases.Conclusions: Conjunctival autografting is a safe and effective procedure in the management of pterygium. The recurrence rate following limbal conjunctival autografting is significantly lower than that following primary conjunctival closure by bare sclera technique.

Sign in / Sign up

Export Citation Format

Share Document