Study on Prescribing Pattern of Fixed Dose Combinations of Antibiotics in a Post-operative Surgical Ward of Tertiary Care Teaching Hospital, India

Author(s):  
R. Velvizhy ◽  
J. Johan Pandian
Author(s):  
Rushi N. Pandya ◽  
Maulik M. Patel ◽  
Varsha J. Patel

Background: Drug use study identifies the problems that arise from prescription and highlights the current approaches to the rational use of drugs. The objective of the study was to assess drug use pattern in patients diagnosed of acute otitis media in tertiary care teaching hospital.Methods: This prospective observational study was carried in the Otorhinolaryngology department of a tertiary care teaching hospital over a period of twelve months. The data collected for patients with acute otitis media included the patient's demographic details and the drugs prescribed. Data were analysed for drug use pattern and cost per prescription and assessment of rationality of prescription.Results: Total 153 patients were analysed, 100 (65.35%) belonged to male patients and 53 (34.65%) belonged to female patients. Children less than 2years age were the most diagnosed with AOM 47.71%, the major diagnostic symptoms were earache (58.16%) and fever (54.90%) and signs were congestion (52.94%) and discharge (43.13%). In a total 153 prescriptions (469 drugs), 33.68% were antimicrobials, followed by mineral supplements (23.67%). Average number of drugs per prescription was found to be 3.0. Most common antibiotic prescribed was amoxicillin (with or without clavulanate) in 142 (92.81%) patients. Paracetamol alone or in fixed dose combination with antihistaminics were prescribed in 131 patients. Average cost per prescription was 87.74(±35.67) Indian rupees. Seventeen (11.11%) prescriptions were rational in all the aspects based on standard guidelines.Conclusions: The present study showed that paracetamol and amoxicillin with or without clavulanate were mostly commonly prescribed in children with AOM. Irrational prescribing was seen in maximum number of cases.


Author(s):  
Rajesh Venkataraman ◽  
Madan Rayamajhi ◽  
Shahinur Islam ◽  
Nanjunda N

 Objectives: The objectives of the study were to study the prescribing pattern on psychotropic agents at psychiatric department at rural tertiary care teaching hospital, B.G. Nagara.Methods: A prospective and observational study was conducted among psychiatric department (either sex) after considering inclusion and exclusion criteria for the period of 6 months and a total of 300 prescriptions were analyzed.Results: A total of 300 psychiatric patients were enrolled, male 170 (56.67%) patients predominated over females 130 (43.33%) patients. Majority of participants were under age group of 31–40 years (28.6%), illiterate (75%), unemployed (52%), and married (84%). Prevalence of mood disorder 109 (36.33%) was high followed by substance used and addictive disorder 53 (17.67%), schizophrenia 46 (15.33%), and psychosomatic medicine 22 (7.33%). Antidepressant (28.59%) was the commonly prescribed group followed by benzodiazepines (14.81%), anticholinergic (7.18%), and anticonvulsants (7.18%). Tricyclic antidepressants drugs amitriptyline (53.44%) was most frequently prescribed an antidepressant. An average number of drugs per prescription was 2.32 out of which 16.91% of drugs were prescribed by their generic name.Conclusion: Selective serotonin reuptake inhibitors (SSRIs) were the most common group, and escitalopram was the most common medication used among the SSRIs. Majority of the drugs were prescribed from essential drug list. This study advocated an overall rational utilization of psychotropic drugs with fewer deviations due to the socioeconomic status of patients and prescription practices of healthcare providers and need to improve prescribing habits to ensure rational use.


Author(s):  
Jeetendra M. Singh ◽  
Tushar C. Baheti ◽  
Rakesh Verma

Background: The present study was designed to assess awareness regarding rational drug therapy and fixed dose combinations (FDC) amongst interns and II MBBS students in a tertiary-care teaching hospital in Maharashtra, India.Methods: This cross-sectional, questionnaire-based study containing MCQ and analytical questions on rational drug therapy, fixed dose combinations and role of Pharmacist in dispensing correct drug to the patients was carried out in both interns (n=80) and II MBBS students (n=100). The completed questionnaires were then collected and analysed statistically for responses.Results: Mean average score obtained by II MBBS students (score - 36.66marks) was significantly better than interns (score- 20marks) which probably may be due to pharmacology teaching they were undergoing. II MBBS students were found to be better informed as compared to the interns (p<0.05) on questions related to rational drug therapy. On the questions related to rationality of FDC in Yes/No type, interns and II MBBS students were found to be equally informed (p>0.05). However, on question related to justification of FDC, interns were found to be better informed as compared to the II MBBS students (p<0.05). On single question pertaining to role of pharmacist, interns were found to be better informed than II MBBS students possibly due to their better understanding of patient-pharmacist relationship.Conclusions: Our study highlights the significance regarding knowledge of rational drug therapy and fixed dose combination (both rational and irrational), both rational and irrational, amongst both interns and II MBBS students while identifying the possible areas of interventions to make them rational clinicians.


Author(s):  
Mohammed Sarfaraz ◽  
A. S. Archana ◽  
Bhavana Kalwa ◽  
Monish Abraham Mathew ◽  
Shilpa Anna Kuriakose ◽  
...  

Background: Anemia is a major public health problem in India affecting people in all age groups with major consequences for human health as well as economic development. Hence the study aims to assess prescribing pattern of physicians in anemia and to create awareness among in-patients in a tertiary care teaching hospital.Methods: A prospective and observational study was carried out in 180 in-patients admitted to General Medicine department in a tertiary care teaching hospital diagnosed with anemia for 6 months. Data was collected from case sheets of patients and assessed for prescribing pattern and direct interview was conducted with patients using standardized KAP questionnaire on anemia.Results: Among 180 in-patients, 126 patients (70%) were females and 54 patients (30%) were males. As part of the therapy, folic acid with vitamin combinations (37 prescriptions) followed by elemental iron with folic acid combinations (32 prescriptions) were most prescribed drugs. KAP questions were scored appropriately and compared with hemoglobin levels. Knowledge level of patients was not significantly correlated (i.e., p=0.254) with their haemoglobin levels. There was a highly significant positive correlation (i.e., p=0.006) between attitude scores of patients and haemoglobin levels. A significant positive correlation (i.e., p=0.001) was found between practice scores of patients and hemoglobin levels.Conclusions: This study clearly showed that prescribing pattern of drugs in anemia patients’ needs to be continuously evaluated. To address the issue of anemia, the patient’s awareness should be enhanced.


Background: Drug use is a tricky task comprises of prescriber, dispenser and the patient. It is influenced by factors such as prescribing experience, drug cost, availability, dispenser knowledge and patient cultural belief. Objective: Current study aim is to assess the drug prescribing pattern in the inpatient ward of the surgery department at tertiary care teaching hospital using WHO prescribing indicators. Material and Methods: A prospective observational study was carried out after the approval from the institutional ethical committee for a period of six months from February 2019 to July 2019. Data were collected, evaluated and represented using descriptive statics and graph wherever applicable. Result: Total of 190 prescriptions were collected and analyzed using WHO prescribing indicators. An average number of the drug was 5.23%. The percentage of the drug from essential medicine list, generic name and Injectables prescribed was 46.93%, 17.68% and 53.16% respectively. Conclusion: Labelling status of prescribing was not according to standards of WHO prescribing indicators and needs special attention. Such study plays a crucial role in the institution level and helps in preparation of evidence-based modules for rational use of drugs.


Sign in / Sign up

Export Citation Format

Share Document