scholarly journals Metastasis Relapse in Synovial Sarcoma of Parotid Gland Followed by Neuropathies and Tissue Damage: A Case Report

Author(s):  
Quratulain Babar ◽  
Emmanuel Ifeanyi Obeagu ◽  
Chikwendu Lawrence Udenze ◽  
Bart I. Ifionu ◽  
C. C. N. Vincent ◽  
...  

Synovial sarcomas are a heterogeneous group of tumors, accounting for 1-2% of adult cancers worldwide. Formation of synovial sarcoma after tissue and nerve injury, radiations induced neuropathies and latent metastasis is those events which are still controversial and need more research. In this report, we present the case of an 18-year-old female patient who developed synovial sarcoma followed by a punch to the face. MRI showed lobulated lesion of 4x3cm appreciated in left parotid space. In spite of Parotidectomy, radiotherapy and radiosurgery followed by MRI and CT-scan latent metastasis was raised in lungs which leads to demise of patient. There are numerous potential etiologic and neurological factors for the development of latent metastasis in synovial sarcoma. Here we will summarize all factors and its complications according to the current literature.

2021 ◽  
Vol 14 (3) ◽  
pp. e237099
Author(s):  
Daanesh Huned ◽  
Juinn Huar Kam ◽  
Lui Shiong Lee ◽  
Raj Vikesh Tiwari

Synovial sarcomas are most commonly localised in extremities, especially in the lower thigh and knee areas. Comprising less than 1% of all malignancies, retroperitoneal synovial sarcoma is very rare with primary synovial sarcoma of the kidney being even more infrequent and difficult to diagnose. We describe a case report of a renal synovial sarcoma in a young adult who was initially managed as a case of Wunderlich’s syndrome secondary to what was believed to be a ruptured renal angiomyolipoma. After biopsy confirmation, the patient was eventually managed with neo-adjuvant chemotherapy followed by a right radical nephrectomy and right hepatectomy. Despite its rarity, synovial sarcoma should be considered as differential diagnosis of a bleeding retroperitoneal soft tissue mass detected in young adults.


2019 ◽  
Vol 128 (1) ◽  
pp. e71-e72
Author(s):  
Dr. Yaser Alhazmi ◽  
Dr. Mark Burke ◽  
Dr. Thom Loree ◽  
Dr. Alfredo Aguirre ◽  
Dr. Chen Gao

2021 ◽  
Vol 97 (2) ◽  
pp. 56-60
Author(s):  
Nadezhda V. Krasnova ◽  
Geliya G. Gimalieva ◽  
Larisa G. Sinitsyna

Patient M., 23 years old, consulted a dermatologist with complaints of rashes on the face, which had bothered since childhood. On objective examination, skin lesions were widespread. A visual examination revealed spots of hypopigmentation, angiofibromas of the face, shagreen fate of the skin, periungual fibromas. She was diagnosed with tuberous sclerosis. Further examination revealed a neoplasm in the brain and right kidney, damage to the lungs, tubular bones, lymphadenopathy. The patient continues to be monitored by a neurologist and therapist. Based on the results of CT scan of the chest organs, an oncologist's consultation was scheduled to conduct an oncology search. Thus, with skin manifestations characteristic of this disease, it is necessary to conduct a comprehensive examination to identify concomitant pathology and early diagnosis of complications.


2003 ◽  
Vol 10 (7) ◽  
pp. 393-395 ◽  
Author(s):  
Linda SL Cheng ◽  
Gary MK Tse ◽  
Wilson WL Li ◽  
TW Lee ◽  
Anthony PC Yim

Synovial sarcomas are uncommon soft tissue tumours. Immunohistochemistry and cytogenetic techniques are essential for proper diagnosis and differentiation from other spindle cell neoplasms. A case of mediastinal synovial sarcoma is described, of which the unusual location, diagnosis and treatment form the basis of this report.


2021 ◽  
Vol 11 (44) ◽  
pp. 174-180
Author(s):  
Ionut Tanase ◽  
Mihaela Neagu ◽  
George Dascalescu

Abstract BACKGROUND. Synovial sarcomas of the soft tissue are a particular type of sarcomas that rarely appear in the head and neck region. CASE REPORT AND COMMENTS. We present the case of a 27-year-old patient diagnosed in 2017 with soft palate biphasic synovial sarcoma who presented with recurrent microepistaxis, nasal obstruction, left cephalalgia and aural fullness in the left ear. The clinical examination showed a tumor with approximately 4/6 cm in diameter, covered with sero-sanguinolent secretions, pulsating in nature, completely obstructing the left choana. The surgical treatment consisted of complete removal of the tumor under endoscopic guidance with electrocauterization of the insertion area, without further postoperative radiotherapy. The histopathological aspect was suggestive for pleomorphic sarcoma, poorly differentiated, confirming the local recurrence of the tumor. The patient also presented lung metastasis from undifferentiated malignant tumor. CONCLUSION. The particularity of this case is represented by the extremely rare occurrence of synovial sarcoma in the head and neck region, especially at the level of the soft palate. Complete resection of the tumor with negative margins represent the mainstay of treatment, associated with adjuvant radiotherapy, with an important role in improving disease-specific survival.


2018 ◽  
Vol 8 (32) ◽  
pp. 237-240
Author(s):  
Andra Virlan ◽  
Nicoleta Schileru ◽  
Amalia Neagu ◽  
Claudiu Manea

Abstract A 40-year-old female patient presented to our clinic for bilateral nasal obstruction, anteroposterior mucopurulent rhinorrhea, recurrent micro-epistaxis, anosmia, left otodynia, fever and sweating. The ENT findings and CT scan detected a septal tumor with predominant extension in the left nostril, with erosive character of the osteo-cartilaginous septal structure, without sinusal involvement and left lateralcervical adenopathy. Resection of the entire septal tumor formation was performed. The histopathological outcome revealed non-Hodgkin’s small-type NK/T extranodal nasal-type lymphoma – immunohistochemical tests confirmed histogenesis.


2017 ◽  
Vol 31 (3) ◽  
pp. 302-305
Author(s):  
Vuk Aleksic ◽  
Milan Spaic ◽  
Miljan Mihajlovic ◽  
Marko Samardzic ◽  
Igor Popovic ◽  
...  

Abstract Meningiomas are common benign intracranial tumors. However, intracranial meningiomas with extracranial extension are exceedingly rare lesions with only a few reported cases in the literature. We report a case of an 86 years old female patient presented with enlarging mass over left parietal region for last 3 years. Besides cosmetic, she had no complaints. Head CT scan with bone window showed a large tumor consisting of intracranial and extracranial part, suggestive for meningioma. Patient was operated, and both parts of tumor were removed. Taking into account surgery indication and patient’s age, bone flap was returned. The postoperative course was uneventful and patient fully recovered. In the case of epicranial tumor attached to the underlying bone, meningioma should be excluded.


2020 ◽  
Vol 7 (3) ◽  
pp. 110-113
Author(s):  
Alexandru Nicolae Vlăescu ◽  
Elena Ioniță ◽  
Andreea Nicoleta Vlăescu ◽  
Florin Anghelina ◽  
Iulică Ioniță ◽  
...  

Laryngeal synovial sarcoma is an extremely rare mesenchymal tumor. During the past four decades, literature findings revealed under 40 cases with this localization. We are bringing forward the case of a 70-year-old male patient who was referred to the ENT Clinic as a respiratory emergency – a tumor obstructing the laryngeal glottis, for which an emergency tracheotomy was initially performed, followed by a CT scan and a biopsy under general anesthesia through suspension videolaringoscopy. The histopathological report was suggestive of a biphasic synovial sarcoma. A multidisciplinary team set the surgical indication for total laryngectomy followed by chemo-radiotherapy. Long-term follow-up is mandatory for recurrence prevention. Patient has checked in for follow-up every 3 months over the past 2 years, with no macroscopic signs of tumoral relapse.


2020 ◽  
Vol 10 (2) ◽  
pp. 206-207
Author(s):  
Md Nematullah ◽  
Keshav Sharma ◽  
Rajveer Singh ◽  
Ranjeet Kumar

Nephrotic syndrome (NS) is the most commonly encountered glomerular diseases in the child. One of the major problems in this disorder is hyper coagulopathy and increased risk of thrombosis. The cause of thrombosis is related to an imbalance of coagulation and anticoagulation factors. A 3-year-old female patient admitted in the pediatric ward with chief complaints is swelling over the face, hand, and legs from 10-12 days and mild pain in the abdomen 2-3 episode. While there are several more common causes of abdominal pain in children with nephrotic syndrome. This study reports that swelling over the face, hand, and legs. If Patients can take proper medication they can decrease the edema and improve their condition. Keywords: Nephrotic syndrome, Anasarca, Edema


Sign in / Sign up

Export Citation Format

Share Document