scholarly journals Diabetes Mellitus: Worst Comorbidity to have in COVID-19 Pandemic

2021 ◽  
pp. 948-955
Author(s):  
Kritarth Sengupta ◽  
Bharat S. Sudame
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Outcome ◽  
Diabetic Patient ◽  
Age Groups ◽  
Medical Attention ◽  
Diabetic Patients ◽  
Adverse Clinical Outcome ◽  
Bidirectional Relationship ◽  
The World ◽  
Novel Coronavirus

Background: Diabetic patients have shown the worst clinical manifestation of the COVID-19. They are at higher risk of being infected and producing severe clinical outcomes, challenging to manage. Also, the share of the diabetic patient among case fatalities is large. Summary: COVID-19 is a disease pandemic that has spread worldwide. All sections and age groups of people worldwide have been affected by the pandemic. Diabetes mellitus is the worst disease to have in OVID-19, as studies have shown some adverse clinical outcome that needs sophisticated medical attention. In lack of resources and overwhelmed infrastructure, the availability of these is tricky. Conclusion: More study is needed about the bidirectional relationship between COVID-19 and diabetes mellitus so that a clearer picture can be emerged out of the fogged situation. Diabetes is already grappling the world, which is suggested by increasing the number of diabetic patient’s number worldwide. Especially in COVID-19, it has become a challenge to contain the disease along with all these comorbidities. The immunosuppressive state brought about by various underlying medical conditions like diabetes mellitus is suitable ground for novel coronavirus to propagate itself.

Association and treatment of diabetes in patients affected by Covid-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1198-1201
Author(s):  
Syed Yasir Afaque
Keyword(s):  
Diabetes Mellitus ◽  
Prognostic Value ◽  
Heart Diseases ◽  
The Novel ◽  
The World ◽  
Treatment Of Diabetes ◽  
Coronavirus Infection ◽  
Composite Outcomes ◽  
Novel Coronavirus ◽  
The Impact

In December 2019, a unique coronavirus infection, SARS-CoV-2, was first identified in the province of Wuhan in China. Since then, it spread rapidly all over the world and has been responsible for a large number of morbidity and mortality among humans. According to a latest study, Diabetes mellitus, heart diseases, Hypertension etc. are being considered important risk factors for the development of this infection and is also associated with unfavorable outcomes in these patients. There is little evidence concerning the trail back of these patients possibly because of a small number of participants and people who experienced primary composite outcomes (such as admission in the ICU, usage of machine-driven ventilation or even fatality of these patients). Until now, there are no academic findings that have proven independent prognostic value of diabetes on death in the novel Coronavirus patients. However, there are several conjectures linking Diabetes with the impact as well as progression of COVID-19 in these patients. The aim of this review is to acknowledge about the association amongst Diabetes and the novel Coronavirus and the result of the infection in such patients.

BIDIRECTIONAL SCREENING FOR TUBERCULOSIS AND DIABETES MELLITUS IN A TERTIARY CARE HOSPITAL IN SOUTH INDIA

2021 ◽  
pp. 93-95
Author(s):  
Arun Babu.V ◽  
Deepak Kanna.K
Keyword(s):  
Diabetes Mellitus ◽  
Health Outcomes ◽  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Hiv Screening ◽  
Care Hospital ◽  
Tuberculosis Patients ◽  
Bidirectional Relationship

Screening for Tuberculosis in people with Diabetes and screening for Diabetes in people with Tuberculosis will allow earlier detection of co-morbidities, leading to better health outcomes. This study carried out in a tertiary care hospital in South India consisted of 500 Diabetic patients and 250 patients of Tuberculosis. In 250 Tuberculosis patients screened for DM, the overall prevalence of DM in TB patients was 24.8%,out of which 17.2 % already had Diabetes and 7.6% was the additional yield during screening. About 500 Diabetes cases screened for tuberculosis, 7.6% had symptoms suggestive of tuberculosis. On further evaluation of these subjects none of them revealed evidence for tuberculosis. There exists a bidirectional relationship between TB and diabetes, and they both impact the presentation of each other. This study highlights the need of routine screening for dysglycemia for all TB patients, especially at the time of diagnosis, similar to HIV screening.

scholarly journals Diabetes mellitus and periodontal diseases: A two way relationship

2021 ◽  
Vol 6 (2) ◽  
pp. 43-56
Author(s):  
Gowhar Nazir ◽  
◽  
Josee Amin ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Systemic Effect ◽  
Diabetic Patients ◽  
Periodontal Infection ◽  
Bidirectional Relationship ◽  
Patients With Diabetes ◽  
Global Health Care

Diabetes mellitus and periodontits are both highly prevalent chronic inflammatory diseases. Both diseases share the same risk factors and are a significant global health care burden adversely affecting the quality of life. Evidence from various studies have demonstrated that diabetes is a major risk factor for periodontal disease and is associated with increased incidence, prevalence and severity of periodontal disease. Hyperglycemia associated with diabetes mellitus results in an increased host immunoinflammatory response which adversely affects the periodontal health. Conversely, periodontits is associated with poor metabolic control in patients with diabetes and increased development of diabetic complications suggesting a bidirectional relationship between the two diseases. Periodontal infection via bacteremia exerts a wide systemic effect by contributing to chronic systemic inflammatory burden worsening diabetic state by increasing insulin resistance. Moreover, studies have demonstrated an improvement in glycemic control following periodontal therapy in prediabetic and diabetic patients with periodontitis.

scholarly journals Pengaruh Ekstrak Undur-undur (Myrmeleon sp) terhadap Glukosa Darah dan Hematokrit pada Tikus Diabetes

2020 ◽  
Vol 9 (2) ◽  
pp. 209
Author(s):  
Djap Hadi Susanto ◽  
Ronald Winardi Kartika ◽  
Pamela Hendra Heng ◽  
Adit Widodo Santoso ◽  
Maria VB Lopulalan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Rats ◽  
Diabetic Patients ◽  
Randomized Experiment ◽  
Traditional Methods ◽  
Major Health ◽  
The People ◽  
The World ◽  
Diabetes Mellitus Treatment ◽  
Methods Of Treatment

Diabetes Mellitus (DM) is one of the major health problems in the world and Indonesia. The prevalence is more increasing and also shows the trend of events is shifting to young age. Diabetes mellitus treatment requires high costs and also a lifetime. Most of the people of Indonesia still use traditional methods of treatment, especially herbs from various biological substances that are available in the environment. Undur-undur (myrmeleon sp.) is believed to have the effect of anti-hyperglycemia, and also anti-viscosity. The aim of this study was to determine anti-hyperglycemia and anti-viscosity of myrmeleon sp. extract in diabetic rats. The design of study is randomized experiment. Diabetic rats were induced by streptozocin 100mg/ kg BW intraperitoneal. Fifty rats were divided into 2 groups administered by Myrmeleon sp. extract dose 0,01ml/ 200 gram BW (100%) and 0,005ml/ 200 gram BW (50%). Myrmeleon sp. shows the effect of anti-hyperglycemic and anti-viscosity in diabetic rats. There was a difference between 50% and 100% doses. The effect of anti-hyperglycemia and anti-viscosity occurs after the second day. Conclusion: the extract of myrmeleon sp. could be considered as one of the traditional treatments of diabetic patients.

scholarly journals The Role of HbA1c in Severity and Mortality Rate of ST Segment Elevation Myocardial Infarction for Hospitalized Libyan Non-Diabetic Patients

2019 ◽  
Vol 12 (3) ◽  
Author(s):  
Hanan KG Altalhi
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Hospital Mortality ◽  
Diabetic Patient ◽  
Hba1c Level ◽  
Diabetic Patients ◽  
St Segment Elevation ◽  
Hospital Patients ◽  
History Of ◽  
Group 2

Background: The severity of coronary artery disease (CAD) is directly related to the quality of glucose control in diabetic patient. Additionally, diabetes is associated with increased mortality following acute myocardial infarction compared to general population. Objectives: To evaluate the association of HbA1c level and severity of CAD, and outcome of non-diabetic patient with STEMI in our hospital. Patients and Methods: 60 consecutives non-diabetic patient with acute ST elevation myocardial infarction were treated with thrombolytic therapy included in the present prospective study. Blood glucose and HbA1c level of all patients were measured within 3 hours of admission. Patient were divided in to 3 groups according to HbA1c level: with cut-off 6.5% as diagnostic criteria of diabetes mellitus according to (American diabetes association) group (1) 6.5%, group (2) 6.5 to 8.5%, group (3) 8.5% and above. In hospital. mortality and morbidities of acute STEMI were compared between groups. Results: The mean age was 63±15 year and mean body mass index was 26. 6±6 kg/m², 24 patients (40%) had history of hypertension, 27 patients (45%) of dyslipidemia, 36 patients (60%) were smoker. We found 45 patients with HbA1c ≤ 6 5%, 5 patients with HbA1c 6.5 -8.5 %, 10 patients with HbA1c ≥ 8.5%. There was strong correlation between admission of HbA1c and admission glucose level (P< 0.001). Infarct size as measured by peak creatinin kinase, was not correlated with HbA1c level. Conclusions: HbA1c is an important risk marker in the absence of history of diabetes mellitus in patients with AMI. The optimal management in these patients may contribute in decrease hospital mortality.

scholarly journals Prevalence of diabetes mellitus in rural population of Mullana, district Ambala, Haryana, India

2018 ◽  
Vol 6 (4) ◽  
pp. 1248
Author(s):  
Nitesh Pradhan ◽  
Abhishek Sachdeva ◽  
Tushar Goel ◽  
Sahil Arora ◽  
Shekhar Barua
Keyword(s):  
Diabetes Mellitus ◽  
Health Care Providers ◽  
Rural Population ◽  
Age Groups ◽  
International Diabetes Federation ◽  
Developed Countries ◽  
Care Providers ◽  
High Prevalence ◽  
The World ◽  
Prevalence Of Diabetes Mellitus

Background: Diabetes mellitus (DM) is a major cause of avoidable blindness in developing and developed countries. The International Diabetes Federation (IDF)’s Diabetes Atlas reports that India has the highest number of people with diabetes (nearly 25%) in the world, and hence considered to be the “Diabetes Capital of the World”.Methods: This is a hospital record based study was planned to estimate the prevalence of Diabetes Mellitus in various age groups in rural population of Mullana, District Ambala(Haryana).Results: Out of 1050 patients screened 50 were found to be having Diabetes mellitus (DM) 1000 were non-diabetic i.e. prevalence of Diabetes mellitus (DM) was found to be 4.76%. Out of 362 males screened 22 were suffering from Diabetes mellitus (DM) i.e. prevalence of 6.07%. Whereas out of 688 females screened 28 were suffering from Diabetes mellitus (DM) i.e. prevalence of 4.06%. Prevalence of Diabetes mellitus (DM) in males was found to be maximum in age group of more than 70 years i.e. 6.97% as compare to female i.e.5.29%.Conclusions: Thus, the current study recorded high prevalence of Diabetes mellitus (DM) among rural population which should be a cause of concern for health care providers. 

scholarly journals COVID-19 MOST AFFECTED AGE GROUPS AND LETHALITY IN EUROPE

2020 ◽  
Vol 2 (SP1) ◽  
pp. 179-184
Keyword(s):  
Age Groups ◽  
Case Fatality ◽  
Prevention Measures ◽  
Global Epidemic ◽  
Number Of Patients ◽  
The World ◽  
The Mean ◽  
Novel Coronavirus ◽  
Very High ◽  
Age Of Death

Introduction: The outbreak of a novel coronavirus disease (COVID-19; previously known as 2019-nCoV) was the beginning of one of the largest and most critical COVID-19 clusters in the world since late December 2019. Despite intensive prevention measures, the epidemic tends to propagate and the number of patients infected is growing. The case-fatality incidence was very high and is driven by very elderly people. Methods: in this study, we collected data from the (Covidgraph.com) database as the number of infection cases in the world reached 2736188 infections and the number of recovery cases reached 751805 and the number of deaths reached 191423.Results: it turns out that the virus infects older people and the older a person is, the higher the chance of infection with the virus. Results from this analysis the mean age of death is 78 years. Data from 106,399 cases and 12,550 deaths in Italy, to 2 April. In Spain, they are based on 7 April, 88,144 cases, and 3,479 deaths. There were less than 80 deaths in patients younger than 50 years of age. Conclusion: Coronavirus is a global epidemic, and it's hard to control, and it's not enough to prevent people from spreading the virus. The age groups most vulnerable to lethality are shown in this paper, in Italy, the virus destroys people over 75 years of age, In Spain, however, the virus destroys people aged over 85 Taking into account numerous comorbidities, including psychiatric, cerebrovascular, endocrine, metabolic, and respiratory disorders.

scholarly journals The prevalence of type 1 diabetes mellitus among adolescents and adults in Lithuania during 1991–2004

Medicina ◽  
2007 ◽  
Vol 43 (3) ◽  
pp. 242 ◽  
Author(s):  
Rytas Ostrauskas
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Age Groups ◽  
Diabetic Patients ◽  
Female Age ◽  
Adolescents And Adults ◽  
The Mean ◽  
Type 1 Diabetic Patients

Objective. The goal of this study was to summarize the data on the prevalence of type 1 diabetes mellitus among Lithuanian population aged more than 15 years. Material and methods. The data on patients aged more than 16 years were collected with the help of general practitioners, endocrinologists, and physicians-internists working in the diabetes care in all towns and regions of Lithuania. The data on patients aged 14 to 16 years were obtained from the National Register of Diabetes Mellitus in Childhood in Lithuania. Results. In Lithuania, on December 31, 1991, there were 2179 adolescent and adult patients with type 1 diabetes mellitus or 75.21 per 100 000 inhabitants of the same age group (95% Poisson CI 72.12–78.43), and at the end of 2004 – 3996 or 140.69 (95% Poisson CI 136.40– 145.12), respectively. During a 14-year period, the mean increase in the number of type 1 diabetic patients was 144.85±23.32 persons per year or 4.66±1.17% or 4.04±1.19 cases per 100 000 population (for males 85.54±10.82 or 5.06±1.02% or 6.81±1.57/100 000 and for females 54.23±9.05 or 3.93±0.86% or 3.56±1.05/100 000). Regression-based linear trends showed that the prevalence of type 1 diabetes mellitus among population aged more than 15 years had a tendency to increase. The prevalence rates of type 1 diabetes mellitus among adolescent and adult subjects, adjusted for Lithuanian male and female age groups, were 80.64/100 000 and 70.23/100 000 in 1991 (P<0.05) and 166.52 and 117.63 in 2004 (P<0.05), respectively. Conclusions. The prevalence of type 1 diabetes mellitus among Lithuanian females aged more than 15 years was lower than among males. The register provides the possibility of highly precise collection of the data on patients from various medical care units in Lithuania.

scholarly journals Focal crisis originating from movement in a hyperglycemic nonketotic patient

1991 ◽  
Vol 49 (2) ◽  
pp. 222-224
Author(s):  
J. Adamo Jr. ◽  
F. Forti
Keyword(s):  
Diabetes Mellitus ◽  
Case Report ◽  
Diabetic Patient ◽  
Serum Levels ◽  
Passive Movement ◽  
Diabetic Patients ◽  
Rare Type ◽  
Initial Manifestation ◽  
The Right

Case report of a long term diabetic patient with partial motor crises originating from passive movement of the right arm. This is a rare type of crisis when compared to spontaneous partial crisis in diabetic patients. Partial crises are often the initial manifestation of diabetes mellitus (about 19% of the cases reported). As in those cases registered in the literature, crisis control in this case was obtained by normalization of glycose serum levels. Possible mechanisms involved in the pathogenesis are discussed.

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