scholarly journals CODON CONTEXT ANALYSIS OF METHANOCALDOCOCCUS JANNASCHII

2009 ◽  
Vol 1 (2) ◽  
pp. 65-69
Author(s):  
Verma DK ◽  
◽  
Gokhale MS
2018 ◽  
Vol 97 (1) ◽  
pp. 97-107 ◽  
Author(s):  
Prosenjit Paul ◽  
Arup Kumar Malakar ◽  
Supriyo Chakraborty

2010 ◽  
Vol 3 (3) ◽  
pp. 355-375 ◽  
Author(s):  
Michelle Billies

The work of the Welfare Warriors Research Collaborative (WWRC), a participatory action research (PAR) project that looks at how low income lesbian, gay, bisexual, transgender, and gender nonconforming (LG-BTGNC) people survive and resist violence and discrimination in New York City, raises the question of what it means to make conscientization, or critical consciousness, a core feature of PAR. Guishard's (2009) reconceptualization of conscientization as “moments of consciousness” provides a new way of looking at what seemed to be missing from WWRC's process and analysis. According to Guishard, rather than a singular awakening, critical consciousness emerges continually through interactions with others and the social context. Analysis of the WWRC's process demonstrates that PAR researchers doing “PAR deep” (Fine, 2008)—research in which community members share in all aspects of design, method, analysis and product development—should have an agenda for developing critical consciousness, just as they would have agendas for participation, for action, and for research.


2019 ◽  
Vol 14 (4) ◽  
pp. 323-332 ◽  
Author(s):  
Priya Narang ◽  
Mehak Dangi ◽  
Deepak Sharma ◽  
Alka Khichi ◽  
Anil Kumar Chhillar

Background: Chikungunya infection flare-ups have manifested in nations of Africa, Asia, and Europe including Indian and Pacific seas. It causes fever and different side effects include muscle torment, migraine, sickness, exhaustion and rash. It has turned into another, startling general medical issue in numerous tropical African and Asian countries and is presently being viewed as a genuine risk. No antiviral treatment or vaccine is yet available for this ailment. The current treatment is centered just on mitigating its side effects. Objective: The objective was to encourage the study on this viral pathogen, by the development of a database dedicated to Chikungunya Virus, that annotates and unifies the related data from various resources. associations while known disease-lncRNA associations are required only. Method: It undertook a consolidated approach for Chikungunya Virus genomic, proteomic, phylogenetics and therapeutic learning, involving the entire genome sequences and their annotation utilizing different in silico tools. Annotation included the information for CpG Island, usage bias, codon context and phylogenetic analysis at both the genome and proteome levels. Results: This database incorporates information of 41 strains of virus causing Chikungunya infection that can be accessed conveniently as well as downloaded effortlessly. Therapeutics section of this database contains data about B and T cell Epitopes, siRNAs and miRNAs that can be used as potential therapeutic targets. Conclusion: This database can be explored by specialists and established researchers around the world to assist their research on this non-treatable virus. It is a public database available from “www.chkv.in”.</P>


2020 ◽  
Author(s):  
Matteo Santon ◽  
Felix Deiss ◽  
Pierre‐Paul Bitton ◽  
Nico K. Michiels

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 427
Author(s):  
Amin Mirzaaghasi ◽  
Yunho Han ◽  
So-Hee Ahn ◽  
Chulhee Choi ◽  
Ji-Ho Park

Exosomes have attracted considerable attention as drug delivery vehicles because their biological properties can be utilized for selective delivery of therapeutic cargoes to disease sites. In this context, analysis of the in vivo behaviors of exosomes in a diseased state is required to maximize their therapeutic potential as drug delivery vehicles. In this study, we investigated biodistribution and pharmacokinetics of HEK293T cell-derived exosomes and PEGylated liposomes, their synthetic counterparts, into healthy and sepsis mice. We found that biodistribution and pharmacokinetics of exosomes were significantly affected by pathophysiological conditions of sepsis compared to those of liposomes. In the sepsis mice, a substantial number of exosomes were found in the lung after intravenous injection, and their prolonged blood residence was observed due to the liver dysfunction. However, liposomes did not show such sepsis-specific effects significantly. These results demonstrate that exosome-based therapeutics can be developed to manage sepsis and septic shock by virtue of their sepsis-specific in vivo behaviors.


Author(s):  
Mario Casillo ◽  
Francesco Colace ◽  
Dajana Conte ◽  
Marco Lombardi ◽  
Domenico Santaniello ◽  
...  

AbstractIn the Big Data era, every sector has adapted to technological development to service the vast amount of information available. In this way, each field has benefited from technological improvements over the years. The cultural and artistic field was no exception, and several studies contributed to the aim of the interaction between human beings and artistic-cultural heritage. In this scenario, systems able to analyze the current situation and recommend the right services play a crucial role. In particular, in the Recommender Systems field, Context-Awareness helps to improve the recommendations provided. This article aims to present a general overview of the introduction of Context analysis techniques in Recommender Systems and discuss some challenging applications to the Cultural Heritage field.


Land ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 490
Author(s):  
Yan-Feng He ◽  
Chie-Peng Chen ◽  
Rung-Jiun Chou ◽  
Hai-Feng Luo ◽  
Jin-Xiong Hou

Over generations, economic development has accelerated traditional settlements in Taiwan while losing traditional culture. In Hakka villages, this is manifested in the changes in defensive spaces, the ‘spirit of place,’ and land use. Although some progress has been made through research into related issues, a correlated view has been missing. To explore the connection between the ‘spirit of place’ and defensive spaces in Wugoushui, a traditional representative settlement in Taiwan, this paper probes three questions: What are the changes in defensive spaces? What are the changes in the spirit of place? What are the connections between them? Taking the sixteen criteria of secure defensive space as the theoretical foundation, through more than a year of structured observations and in-depth interviews with ten representative residents, and based on context analysis and site analysis of the information collected, this paper has concluded that, although the actual functionality of Wugoushui settlement’s spiritual, behavioural, and physical defences have disappeared, cultural characteristics related to the settlement traditions, including religious beliefs, trust, sense of belonging, street network, nodes, institutions, territory, and social networks, constitute a concrete manifestation of the defensive space and the spirit of place as of today. This research contributes to developing a theory of the relevance of the spirit of place to the defensive space of settlements from a sustainability perspective and improving the cultural preservation and land management of traditional settlements.


2020 ◽  
Vol 6 (1) ◽  
pp. 68-76 ◽  
Author(s):  
Lorena Pérez Macías ◽  
María del Mar Sánchez Ramos ◽  
Celia Rico

AbstractThe use of machine translation in the field of migrations seems to be very limited and, in view of the latest developments, it is only natural to explore its usefulness in the migratory context. In an attempt to introduce this technology into this particular area, this article reports on a qualitative study on translators’ perceptions towards machine translation and post-editing tasks. The findings of the study indicate that both are not widely developed within the migratory context and further work is required. Based on our findings, we believe that this study can contribute to opening the way for machine translation and post-editing tasks to be included into the field of migrations.


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