scholarly journals Epidermal Cyst of the Breast Treated by Vacuum-Assisted Biopsy

2013 ◽  
Vol 98 (1) ◽  
pp. 65-69 ◽  
Author(s):  
Toshiyuki Yamaguchi ◽  
Norihiro Ojima ◽  
Masahiro Hayashi ◽  
Nobuo Komatsu ◽  
Shin-ichi Hashimoto ◽  
...  
Keyword(s):  
Left Breast ◽  
Epidermal Cyst ◽  
Outer Quadrant ◽  
Radiologic Findings ◽  
Biopsy Device ◽  
Stratified Squamous Epithelium ◽  
Waxy Material ◽  
Ultrasonographic Guidance ◽  
Real Time Ultrasonography ◽  
Firm Mass

Abstract A 38-year-old woman presented for evaluation of a firm mass (measuring 20 × 20 mm) in the upper outer quadrant of her left breast. On the basis of the clinical and radiologic findings, we diagnosed a benign breast tumor and scheduled removal by a hand-held vacuum-assisted biopsy device (VABD) under ultrasonographic guidance. Because the first specimen removed from the tumor was white, flaky, and waxy material, we strongly suspected that the lesion was an epidermal cyst. We continued VABD treatment until the tumor was invisible on real-time ultrasonography. Histologic examination demonstrated that the tumor was composed of mature stratified squamous epithelium and laminated layers of keratin, findings consistent with a diagnosis of epidermal cyst. These cysts rarely occur in the breast and are sometimes difficult to distinguish from breast cancer. To our knowledge, this is the first report of an epidermal cyst treated by VABD.

Adenoid Cystic Carcinoma of the Breast detected with Contrast-Enhanced Spectral Mammography: A Case Report

2020 ◽  
Vol 16 ◽  
Author(s):  
Yun-Chung Cheung ◽  
Shir-Hwa Ueng ◽  
Shu-Hang Ng ◽  
Wen-Lin Kuo
Keyword(s):  
Left Breast ◽  
Breast Cancers ◽  
Resonance Imaging ◽  
Carcinoma Of The Breast ◽  
Outer Quadrant ◽  
Additional Information ◽  
Adenoid Cystic ◽  
Modern Technique ◽  
Contrast Enhanced ◽  
Rim Enhancement

Background: Contrast-enhanced spectral mammogram (CESM) is a modern technique providing additional information to detect or diagnose the breast cancers. Introduction: We present a rare ACC of breast on CESM. Methods: A 49-year-old woman with surgicopathological proved ACC is reported with features on CESM, sonography and contrast-enhanced magnetic resonance imaging (CE-MRI). Results: Sonography revealed a 1.4 cm × 1.2 cm × 1 cm circumscribe round mass in the upper outer quadrant of the left breast that was diagnosed to fibroadenoma. The mammogram did not show any discernible mass, however the recombined subtracted images displayed a circumscribe mass with thin rim enhancement and enhanced internal patches that were resembling to CE-MRI. Finally, the mass was proved to ACC. Conclusion: CESM facilitates detection of an isodense cancer and provides the enhanced features for differential diagnosis. Resembling CE-MRI, CESM displayed rim enhancement and internal enhanced patches as diagnostic clues for this case of ACC.

Should a Woman Age 70 to 80 Years Receive Radiation After Breast-Conserving Surgery?

2013 ◽  
Vol 31 (19) ◽  
pp. 2377-2381 ◽  
Author(s):  
Jaroslaw T. Hepel ◽  
David E. Wazer
Keyword(s):  
Progesterone Receptor ◽  
Physical Examination ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Wide Local Excision ◽  
Core Biopsy ◽  
Left Breast ◽  
Outer Quadrant ◽  
Axillary Lymphadenopathy ◽  
Node Biopsy

Case 1: A 72-year-old woman presents with a palpable mass detected during yearly physical examination by her primary care physician. She has controlled hypertension and remains active, playing tennis three times a week. Physical examination reveals a 1.5 cm mass in the upper outer quadrant of the left breast with no palpable axillary lymphadenopathy. Diagnostic imaging reveals a suspicious mass, and core biopsy confirms invasive ductal carcinoma (IDC) that is estrogen receptor moderately positive (60%), progesterone receptor negative and Her2-neu that is not overexpressed. She undergoes a wide local excision and sentinel node biopsy. Pathology reveals a 1.5 cm IDC that is high grade without lymphovascular invasion (LVI). The margins are negative with the closest laterally at 2 mm. One sentinel node is negative for metastasis. Case 2: A 72-year-old woman presents with an abnormal screening mammogram that shows a small area of architectural distortion in the upper outer quadrant of the left breast ( Fig 1 ). She is a former smoker with mild chronic obstructive pulmonary disease and has mild to moderately symptomatic osteoarthritis managed with a nonsteroidal anti-inflammatory agent. She remains active and independent. Physical examination reveals neither palpable breast mass nor axillary lymphadenopathy. Diagnostic ultrasound confirms a 1.8 cm mass, and core biopsy reveals IDC that is estrogen and progesterone receptor strongly positive (> 90%) and Her2-neu that is not overexpressed. She undergoes a wide local excision and sentinel node biopsy. Pathology reveals a 1.9 cm IDC that is low grade. The margins are widely negative at > 5 mm and there is no LVI. One sentinel node is negative for metastasis.

A Peculiar Form of Breast Fat Necrosis Simulating Hyaline Ring Granuloma (So-called Pulse Granuloma): A Rare Complication of Hyperparathyroidism

2017 ◽  
Vol 26 (1) ◽  
pp. 52-55 ◽  
Author(s):  
Maria García-Martos ◽  
Angel Panizo-Santos
Keyword(s):  
Rare Complication ◽  
Degenerative Change ◽  
Malignant Lesion ◽  
Left Breast ◽  
Histopathological Study ◽  
Imaging Features ◽  
Fat Necrosis ◽  
Outer Quadrant ◽  
Peculiar Form ◽  
History Of

Pulse granuloma is a rare, foreign body inflammatory reaction that occurs mainly in the oral cavity. It is exceedingly rare elsewhere, with only isolated cases described in the literature. We report the case of a 79-year-old woman with a history of normocalcemic hyperparathyroidism who presented to our hospital with a painful 4-cm lump in the upper quadrants—upper outer quadrant of her left breast. The clinical and radiological (BIRADS-5) findings were indicative of a malignant lesion. However, core needle biopsy revealed features simulating hyaline ring granuloma (pulse granuloma-like). A definitive diagnosis of lipomembranous fat necrosis was made by identifying its characteristic histomorphology. Histopathological study is essential to establish an exact diagnosis since clinical and imaging features may mimic breast carcinoma. To our knowledge, this is the first reported case of a hyaline ring granuloma-like in the breast, which may represent a peculiar form of degenerative change of lipomembranous fat necrosis.

scholarly journals The Role of Postmastectomy Radiotherapy in Locally Advanced Breast Cancer After Pathological Complete Response to Neoadjuvant Chemotherapy

ONCOLOGY ◽  
2021 ◽  
pp. 139-143
Author(s):  
Christian Haydeé Flores-Balcázar ◽  
Francisco Javier Castro-Alonso ◽  
Tania Patricia Hernández-Barragán ◽  
Jesús Delgado-de la Mora ◽  
Antonio Daidone ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Neoadjuvant Treatment ◽  
Left Breast ◽  
Tumor Board ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Outer Quadrant ◽  
Normal Morphology ◽  
Axillary Nodes

A previously healthy woman, aged 32 years, presented to the oncology clinic with a 6-month history of left-breast tumor, mastalgia, and swollen axillary nodes. Physical examination was relevant for a 6-cm palpable mass in the upper outer quadrant of the left breast and an ipsilateral 2-cm, nonfixed axillary lymph node. Mammography showed a 1-cm mass in the upper outer quadrant, a 5.2-cm mass in the lower outer quadrant, and enlarged pathologic lymph nodes (BI-RADS category 5 disease). Breast ultrasound revealed 3 axillary lymph nodes with cortical thickening and loss of normal morphology (the largest with a 2.6-cm length in the long axis) (Figure 1A-B). The breast's core biopsy revealed a grade 3 apocrine invasive carcinoma with lymphovascular invasion; immunohistochemistry testing showed HER2-negative, hormone receptor-negative disease (estrogen receptor, 0%; progesterone receptor, 0%; HER2-negative, Ki67, 50%) (Figure 2A-B). A fine-needle aspiration biopsy of the axillary lymph nodes showed invasive breast carcinoma as well. Bone scintigraphy and a chest/abdomen CT scan ruled out metastatic disease. Upon initial diagnosis, clinical stage was deemed as cT3N1M0 (American Joint Committee on Cancer 8th edition: anatomic stage IIIA, clinical prognostic stage IIIC). After a multidisciplinary tumor board discussion, the patient underwent neoadjuvant chemotherapy with weekly paclitaxel, followed by 4 cycles of dosedense doxorubicin plus cyclophosphamide. After completing neoadjuvant treatment, clinical examination was relevant for a residual 1-cm palpable left breast mass and no palpable axillary nodes. Mammography and breast ultrasound showed a 77% partial response in the primary tumors, and axillary nodes with normal morphology and size (Figure 1C-D). Due to multicentric tumor disease, breast-conserving surgery would not confer satisfactory cosmetic results on her, and a modifi ed radical mastectomy with intraoperative sentinel lymph node biopsy (and second-stage breast reconstruction) was planned. However, during surgery, the surgeons failed to identify the mapped lymph node, and level I-III axillary lymph node dissection was performed. The pathology report described complete pathological response: Miller and Payne criteria grade 5 response with the absence of malignant cells within the mastectomy specimen and in 24 lymph nodes (Figure 2C-E). Pathological staging after neoadjuvant treatment concluded ypT0N0M0 disease. Subsequent treatment for this patient was discussed in another tumor board.

scholarly journals Pure Mucinous Breast Carcinoma with Micropapillary Pattern (MUMPC): A Case Report

2019 ◽  
Vol 12 (2) ◽  
pp. 554-559
Author(s):  
Yuka Asano ◽  
Shinichiro Kashiwagi ◽  
Mizuki Nagamori ◽  
Sayaka Tanaka ◽  
Yuko Kuwae ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Left Breast ◽  
World Health ◽  
Histopathological Diagnosis ◽  
Axillary Lymph ◽  
Invasive Micropapillary Carcinoma ◽  
Outer Quadrant ◽  
Atypical Cells ◽  
Micropapillary Pattern ◽  
Mucinous Breast Carcinoma

Pure mucinous breast carcinoma with micropapillary pattern (MUMPC) was proposed as a new histopathological variant of pure mucinous carcinoma (PMC) with tumor cells forming a micropapillary architecture. The Classification of Tumours of the Breast by the World Health Organization, however, does not differentiate MUMPC as a distinct subtype. There is currently no consensus whether tumors that exhibit these features are classified as PMC or invasive micropapillary carcinoma (IMPC) with associated mucin production. A 45-year-old woman was examined for a tumor in her left breast. Upon physical examination, an elastic hard mass of around 5 cm along with accompanying skin flare and ulceration was palpated in the upper outer quadrant of the left breast. Mammary ultrasonography revealed a clearly marginated hypoechoic tumor of 55.0 × 46.9 × 37.0 mm in size in the upper outer quadrant of the left breast. A vacuum-assisted biopsy (VAB) was performed in the same site and histopathological diagnosis of PMC was made. Contrast-enhanced magnetic resonance imaging (MRI) showed a T1W1 low-intensity signal and a T2W1 high-intensity signal at the primary focus, ring enhancement of the tumor margin, and stranding enhancement inside the tumor. A preoperative diagnosis of left breast cancer (PMC), cT4bN1M0, stage IIIB, luminal B-like was made. We performed a simple mastectomy with axillary lymph node dissection. A 55.0 × 48.1 × 37.1 mm tumor with the gelatinous cut surface was excised. Histopathological examination of the excised specimen revealed mucin lake formation in the tumor containing clusters of atypical cells. The atypical cells showed swollen, irregular nuclei and a papillary growth pattern that lead to the diagnosis of MUMPC.

scholarly journals Study of Breast Lump by FNAC and Distribution of Disease Pattern: A Study of 275 Cases in Bangabandhu Sheikh Mujib Medical University

2008 ◽  
Vol 11 (Number 2) ◽  
pp. 3-8
Author(s):  
A H M O Farooque ◽  
A J E N Rahman ◽  
S Akhter ◽  
S Begum
Keyword(s):  
Duct Cell ◽  
Left Breast ◽  
Benign Disease ◽  
Breast Lump ◽  
Outer Quadrant ◽  
Fine Needle ◽  
Fibrocystic Change ◽  
Disease Pattern ◽  
A Prospective Study ◽  
Medical University

A prospective study of breast lump by FNAC was carried out in Bangabandlut Sheikh Mr Medical University, Dhaka during the period of 15 October 2002 to 17 July 2003 W evaluate the ',mum of disease pattern. A total of 275 patients with breast lump uuderwent fine needle aspirftion cytology (FNAC) examinatiae. Out of 275 lumps examined. 145 (52.5%) wem in the if breast, of which 74 (2690%) were located in the upper outer quadrant. The cytological diagnoses were benign in 213 (77.45%) cases, malign., in 32 (//.63%) cases, suspicions in 2 (072%) cases and unsatisfOctoly in 28 (10.18%) cases. Of the benign disease. the most common lesions were.fibroadenoma 102 (47.5%)followed by fibrocystic change 64 (30.04%1 Of the malignant cases. most common breast carcinoma was duct cell carcinoma 30 (93.75%1 The incidence of built benign and malignant diseases were more in left breast and.frequent in tipper and outer quadrant.

scholarly journals Breast Leiomyosarcoma: A Systematic Review and Recommendations for Management

2019 ◽  
Vol 104 (5-6) ◽  
pp. 196-202
Author(s):  
Mohammed Iyoob Mohammed Ilyas ◽  
Sharique Nazir ◽  
Philip Q. Xiao
Keyword(s):  
Systematic Review ◽  
Core Biopsy ◽  
Residual Tumor ◽  
Left Breast ◽  
Excision Biopsy ◽  
Skin Involvement ◽  
Breast Parenchyma ◽  
Outer Quadrant ◽  
Simple Mastectomy

Background Leiomyosarcomas of breast are very rare tumors, with only 54 cases reported in the literature to date. Methods We report a case of leiomyosarcoma in a 52-year-old woman who presented with a painless left breast mass in the upper outer quadrant of her left breast. It measured about 6 cm in diameter and was located within the breast parenchyma with no skin involvement. Mammogram was suggestive of BI-RADS IV lesion, and core biopsy of the lesion was inconclusive. Results Histopathology and immunohistochemistry of the excision biopsy of the mass confirmed the diagnosis of leiomyosarcoma approaching the specimen margins. The patient underwent simple mastectomy, which did not reveal any residual tumor or additional lesions. Follow-up for a year after her mastectomy did not show any local or systemic recurrence. Conclusions We reviewed the literature and summarize our findings as recommendations for management of leiomyosarcoma of breast.

scholarly journals Dermatofibrosarcoma protuberans of the breast: A case report of a rare breast tumour

2021 ◽  
Vol 11 (2) ◽  
pp. 112-116
Author(s):  
CD Emegoakor ◽  
HC Nzeako ◽  
MI Nwosu ◽  
ME Chiemeka ◽  
FE Menkiti
Keyword(s):  
Dermatofibrosarcoma Protuberans ◽  
Breast Tumour ◽  
Left Breast ◽  
Resection Margins ◽  
Case Presentation ◽  
Malignant Breast ◽  
Similar Appearance ◽  
Slow Growing ◽  
Firm Mass

Introduction: Dermatofibrosarcoma protuberans (DFSP) is an intermediate and slow-growing sarcoma, arising most commonly in the trunk and extremities and rarely in the breast. It may be recurrent, but metastasis is rare. Excision with good resection margins reduces the rate of recurrence. Case Presentation: A 28-year-old lady presented with a painless lump in the left breast of 16 years duration. Examination revealed an ulcerated firm mass, well defined, with perilesional nodules on the skin of the breast. Wedge biopsy favoured Borderline Phylloides Tumour over DFSP. Patient was offered mastectomy and the histology of the specimen confirmed Fibrosarcomatous DFSP. Conclusion: This stresses the importance of histology in diagnosing a rare breast tumour. This is very important because it may show similar appearance to other benign and malignant breast lesions, which makes clear the role of pathological investigation to make a definitive diagnosis.

scholarly journals Tubercular Breast Lesion A Great Mimicker of Carcinoma Breast

2013 ◽  
Vol 3 (1) ◽  
pp. 99-102 ◽  
Author(s):  
BNK Kumar ◽  
Bhargav Pandya ◽  
D Das ◽  
PN Sheeramulu
Keyword(s):  
Breast Carcinoma ◽  
Rare Disease ◽  
Female Patient ◽  
Breast Lesion ◽  
Left Breast ◽  
Breast Abscess ◽  
Outer Quadrant ◽  
Carcinoma Breast ◽  
Breast Tuberculosis ◽  
Multiparous Women

Breast tuberculosis is uncommon entity with confusing clinical, radiological and even microbiological presentation which is often misdiagnosed as breast carcinoma or breast abscess.1 A 28 year old female patient presented with a swelling in outer quadrant of left breast which resembled carcinoma of breast but on ultrasound a hypoechoic lesion was noted which turned out to be tuberculosis on histopathology.Conclusion: Breast tuberculosis (TB) is a rare disease typically affecting young lactating multiparous women and can present either as an abscess or as a unilateral, painless breast mass which can easily be confused with carcinoma.2, 3 Nepalese Journal of Radiology / Vol.3 / No.1 / Issue 4 / Jan-June, 2013 / 99-102 DOI: http://dx.doi.org/10.3126/njr.v3i1.8822

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